MP:0000030 | abnormal tympanic ring morphology | "malformed bony ring at the ear canal to which the tympanic membrane is attached" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:23837] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Tcfap2a-cre)1Will/0 Genetic Background: involves: 129X1/SvJ * C57BL/6
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MP:0000040 | absent middle ear ossicles | "missing small bones of the tympanic cavity" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:1776] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Tcfap2a-cre)1Will/0 Genetic Background: involves: 129X1/SvJ * C57BL/6
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MP:0000066 | osteoporosis | "reduction in bone mass or atrophy of skeletal tissue; may lead to skeletal fragility" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:57315] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Ctsktm1(cre)Ska/Ctsk+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrlj * CBA/JNCrlj
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1+,Ctsktm1(cre)Ska/Ctsk+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrlj * CBA/JNCrlj
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Lyz2tm1(cre)Ifo/Lyz2+ Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1+,Lyz2tm1(cre)Ifo/Lyz2+ Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1+,Tg(Tek-cre)1Ywa/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1+,Ppargtm1.1(tTA)Jmgr/Pparg+,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0000067 | osteopetrosis | "excessive formation of dense trabecular bone and excessive calcified cartilage formation; may lead to anemia and extramedullary hematopoiesis " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MeSH:National Library of Medicine - Medical Subject Headings, 2003] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1+,Tg(Tek-cre)1Ywa/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Ppargtm1.1(tTA)Jmgr/Pparg+,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Ppargtm1.1(tTA)Jmgr/Pparg+,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
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MP:0000073 | absent craniofacial bones | "missing skeletal elements comprising the cranium and face" [J:35802] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,H2afvTg(Wnt1-cre)11Rth/? Genetic Background: involves: 129/Sv * C57BL/6 * CBA
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MP:0000074 | abnormal neurocranium morphology | "malformed bones of the skull enclosing the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:55583] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Tcfap2a-cre)1Will/0 Genetic Background: involves: 129X1/SvJ * C57BL/6
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MP:0000087 | absent mandible | "missing the lower bony framework of the mouth where the inferior teeth are held" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Tcfap2a-cre)1Will/0 Genetic Background: involves: 129X1/SvJ * C57BL/6
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+,H2afvTg(Wnt1-cre)11Rth/0 Genetic Background: involves: 129 * C57BL/6 * CBA/J
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MP:0000111 | cleft palate | "congenital fissure of the tissues normally uniting to form the palate" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840] |
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Allelic Composition: Axin1tm3Cos/Axin1tm4Cos Genetic Background: involves: 129S6/SvEvTac * FVB/N
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1tm1Mmt,Osr2tm5(cre)Jian/Osr2+ Genetic Background: involves: 129X1/SvJ
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MP:0000116 | abnormal tooth development | "anomalous formation of the teeth" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1tm1Mmt,Osr2tm5(cre)Jian/Osr2+ Genetic Background: involves: 129X1/SvJ
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MP:0000128 | growth retardation of molars | "developmental delay of the growth of the molars" [J:17489] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1+,Osr2tm2(cre)Jian/Osr2+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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MP:0000130 | abnormal cancellous bone morphology | "structural anomaly of bone that has a latticelike or spongy structure" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Ctnnb1tm1Max/Ctnnb1tm2Kem,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1tm1Mmt,Tg(Mx1-cre)1Cgn/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Mx1-cre)1Cgn/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Ppargtm1.1(tTA)Jmgr/Pparg+,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1+,Ppargtm1.1(tTA)Jmgr/Pparg+,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Ppargtm1.1(tTA)Jmgr/Pparg+,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
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MP:0000137 | abnormal vertebrae morphology | "malformed bony segment of the spinal column" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Gt(ROSA)26Sortm1(Ctnnb1)Kem/Gt(ROSA)26Sortm1(Ctnnb1)Kem,Tg(Cdx1-cre)23Kem/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * FVB
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MP:0000150 | abnormal rib morphology | "malformed bones forming the bony wall of the chest" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:50311] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Gt(ROSA)26Sortm1(Ctnnb1)Kem/Gt(ROSA)26Sortm1(Ctnnb1)Kem,Tg(Cdx1-cre)23Kem/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * FVB
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MP:0000154 | rib fusion | "appearance of one or more ribs as a single structure" [J:62022, J:62023] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Gt(ROSA)26Sortm1(Ctnnb1)Kem/Gt(ROSA)26Sortm1(Ctnnb1)Kem,Tg(Cdx1-cre)23Kem/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * FVB
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MP:0000163 | abnormal cartilage morphology | "anomalous structure or development of the nonvascular, resilient, flexible connective tissue found primarily in joints, walls of the throax, and tubular structures, but which also comprises most of the skeleton in early fetal life " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Psen1tm1Jzt/Psen1tm1Jzt Genetic Background: involves: C57BL/6 * CBA
Allelic Composition: Ctnnb1tm1Max/Ctnnb1tm2Kem,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Twist2tm1(cre)Dor/Twist2+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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MP:0000164 | abnormal cartilage development | "anomalous formation of the nonvascular, resilient, flexible connective tissue found primarily in joints, walls of the throax, and tubular structures, but which also comprises most of the skeleton in early fetal life " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Tcfap2a-cre)1Will/0 Genetic Background: involves: 129X1/SvJ * C57BL/6
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MP:0000165 | abnormal hypertrophic chondrocyte zone | "anomaly of the cartilage cell matrix layer " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58795] |
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Allelic Composition: Ctnnb1tm1Yy/Ctnnb1tm1.1Yy,Ptch1tm1Yy/Ptch1tm1.1Yy,Tg(Col2a1-cre)1Bhr/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
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MP:0000166 | abnormal chondrocyte morphology | "anomalous structure, organization, or differentiation of nondividing cartilage cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:40203] |
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Allelic Composition: Psen1tm1Jzt/Psen1tm1Jzt Genetic Background: involves: C57BL/6 * CBA
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MP:0000175 | absent bone marrow cell | "lack of cells that make up the core cavities of bones" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Ppargtm1.1(tTA)Jmgr/Pparg+,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
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MP:0000208 | decreased hematocrit | "less than the average percentage of a volume of a blood sample occupied by red blood cells" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Amhr2tm3(cre)Bhr/Amhr2+,Ctnnb1tm1Mmt/Ctnnb1+,Ptentm1Hwu/Ptentm1Hwu Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ
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MP:0000218 | increased WBC count | "greater than normal WBC numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2(Nfkbia)Rsu/Ctnnb1+,Tg(CMV-cre)1Cgn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6
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MP:0000219 | increased neutrophil count | "greater than normal neutrophil numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Prdm4tm1b(EUCOMM)Liz/Prdm4tm1b(EUCOMM)Liz Genetic Background: involves: 129S/SvEv * C57BL/6 * CBA
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MP:0000240 | extramedullary hematopoiesis | "formation and development of blood cells outside the bone marrow, e.g., in the spleen, liver, or lymph nodes" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Amhr2tm3(cre)Bhr/Amhr2+,Ctnnb1tm1Mmt/Ctnnb1+,Ptentm1Hwu/Ptentm1Hwu Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Ppargtm1.1(tTA)Jmgr/Pparg+,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Ppargtm1.1(tTA)Jmgr/Pparg+,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
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MP:0000322 | increased granulocyte number | "greater than expected number of leukocytes that have abundant granules in the cytoplasm: basophils, neutrophils, or eosinophils" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2(Nfkbia)Rsu/Ctnnb1+,Tg(CMV-cre)1Cgn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6
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MP:0000324 | increased mast cell number | "greater than expected number of the granulated cells found in most tissues and which contain large amounts of histamine and heparin in granules" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(KRT14-cre/ERT)20Efu/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1
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MP:0000333 | decreased bone marrow cell number | "decreased number of cells that make up the core cavities of bones when compared to the norm" [tc:Teresa Chu , Mouse Genome Informatics Curator, J:60896] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1+,Ppargtm1.1(tTA)Jmgr/Pparg+,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Lyz2tm1(cre)Ifo/Lyz2+ Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Ppargtm1.1(tTA)Jmgr/Pparg+,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
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MP:0000346 | broad head | "a greater ear- to -ear distance resulting in the appearance of a wide face and a flattened snout" [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator] |
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Allelic Composition: Hoxb13tm2Mrc/Hoxb13tm2Mrc,Hoxd13tm1Mrc/Hoxd13tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0000352 | decreased cell proliferation | "less than the normal growth and reproduction of similar cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: ClppGt(IST13563G11)Tigm/ClppGt(IST13563G11)Tigm Genetic Background: involves: C57BL/6N
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(KRT14-cre)#Smr/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J
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MP:0000364 | abnormal vascular regression | "premature regression or persistence of vessels programmed to regress and/or loss of vessels not programmed to regress" [smb:Susan M. Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Nrarptm1Vlcg/Nrarp+ Genetic Background: involves: C57BL/6J
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MP:0000367 | abnormal coat/ hair morphology | "anomalous color, structure, growth, or texture of the hair" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1tm1(Nfkbia)Rsu Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0000377 | abnormal hair follicle | "malformed invagination of the epidermis from which the hair shaft develops" [J:65031] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(KRT5-rtTA)#Glk/0,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(Krt1-15-cre/PGR)22Cot/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
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MP:0000378 | absent hair follicles | "missing epidermal invaginations from which the hair shaft develops" [J:65039] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm4Wbm/Ctnnb1tm4Wbm,Tg(KRT14-cre)1Efu/0 Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Ctnnb1tm4Wbm/Ctnnb1+,Tg(KRT14-cre)1Efu/0 Genetic Background: involves: 129P2/OlaHsd
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MP:0000379 | reduced hair follicle number | "fewer number of the epidermal invaginations from which the hair shaft develops" [J:15108] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(KRT5-rtTA)#Glk/0,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N
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MP:0000392 | accelerated hair follicle regression | "quicker than average length of time for onset of catagen phase of the cyclic transformation of the hair follicle" [J:65034] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(KRT5-rtTA)#Glk/0,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N
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MP:0000400 | abnormal awl hair | "anomalies of truncal hairs that contain two or more air cells in the medulla" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Cdkn1atm1Tyj/Cdkn1atm1Tyj,Ptentm1Hwu/Ptentm1Hwu,Tg(Fabp1-cre)1Jig/0 Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * FVB/N
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MP:0000402 | abnormal zigzag hairs | "anomalies of truncal hairs that contain one air cell in the medulla" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Corintm2(cre)Bamo/Corin+,Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
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MP:0000405 | abnormal auchene hairs | "anomalies of truncal hairs that contain two or more air cells in the medulla" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Cdkn1atm1Tyj/Cdkn1atm1Tyj,Ptentm1Hwu/Ptentm1Hwu,Tg(Fabp1-cre)1Jig/0 Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * FVB/N
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MP:0000414 | alopecia | "absence of hair or loss of hair; not usually in reference to primary genetic hairlessness but may be due to dietary, stress, secondary to immune condition" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:30772, J:33796] |
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Allelic Composition: Hoxb4tm1Nrm/Hoxb4tm1Nrm Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Ctnnb1tm4Wbm/Ctnnb1tm4Wbm,Krt14tm1.1(cre)Wbm/Krt14+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2(Nfkbia)Rsu/Ctnnb1+,Tg(CMV-cre)1Cgn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6
Allelic Composition: Ctnnb1tm4Wbm/Ctnnb1+,Tg(KRT14-cre)1Efu/0 Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Msx2-rtTA)885Lma/0,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129 * 129X1/SvJ * C57BL/6
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MP:0000416 | sparse fur | "fur that is significantly less dense" [J:46854] |
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Allelic Composition: Ctnnb1tm2(Nfkbia)Rsu/Ctnnb1+,Tg(CMV-cre)1Cgn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Gt(ROSA)26Sortm1(Ctnnb1)Kem/Gt(ROSA)26Sortm1(Ctnnb1)Kem,Tg(Foxn1-cre)1Tbo/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6
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MP:0000418 | patchy hair | "uneven spots of hair growth on the body" [J:26975] |
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Allelic Composition: Apctm3Mmt/Apc+ Genetic Background: involves: 129X1/SvJ * C57BL/6N
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Gt(ROSA)26Sortm1(Ctnnb1)Kem/Gt(ROSA)26Sor+,Tg(Foxn1-cre)1Tbo/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6
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MP:0000423 | delayed hair regrowth | "slow initiation and asynchrony of the hair growth cycle (anagen) after catagen phase " [J:61509] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Corintm2(cre)Bamo/Corin+,Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
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MP:0000428 | abnormal craniofacial morphology | "anomalous structure or development of the face and/or cranium" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Cdkn2atm2.1Rdp/Cdkn2a+,Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn,Tg(Pdx1-cre)89.1Dam/0 Genetic Background: involves: 129 * C57BL/6 * CBA * FVB/N
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,H2afvTg(Wnt1-cre)11Rth/0 Genetic Background: involves: 129 * C57BL/6 * CBA/J
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Gt(ROSA)26Sortm1(Ctnnb1)Kem/Gt(ROSA)26Sor+,H2afvTg(Wnt1-cre)11Rth/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6J * CBA/J
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Msx2-rtTA)885Lma/0,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129 * 129X1/SvJ * C57BL/6
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MP:0000432 | abnormal head morphology | "anomalous structure or development of the portion of the body containing the brain and organs of sight, hearing, taste, and smell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Axin1tm3Cos/Axin1tm4Cos Genetic Background: involves: 129S6/SvEvTac * FVB/N
Allelic Composition: Ctnnb1Bfc/Ctnnb1+ Genetic Background: either: (involves: BALB/cCrl * C3H/HeNCrl) or (involves: BALB/cCrl * C3H/HeNCrl * C57BL/6)
Allelic Composition: Ctnnb1Bfc/Ctnnb1+,Dkk1tm1Lmgd/Dkk1+ Genetic Background: either: (involves: 129/Sv * BALB/cCrl * C3H/HeNCrl) or (involves: 129/Sv * BALB/cCrl * C3H/HeNCrl * C57BL/6)
Allelic Composition: Ctnnb1tm1.2Wvv/Ctnnb1tm1.2Wvv Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
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MP:0000433 | microcephaly | "an abnormally small head" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ctnnb1tm1.2Wvv/Ctnnb1tm1.2Wvv Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
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MP:0000436 | abnormal head movements | "anomalous motion of the portion of the body containing the brain and organs of sight, hearing, taste, and smell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Pvalbtm1(cre)Arbr/Pvalb+ Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0000438 | abnormal skull morphology | "anomalous structure or development of the cranium" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Ctnnb1tm1.2Wvv/Ctnnb1tm1.2Wvv Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
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MP:0000440 | domed skull | |
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Allelic Composition: Psen1tm1Jzt/Psen1tm1Jzt Genetic Background: involves: C57BL/6 * CBA
Allelic Composition: Ctnnb1tm1Yy/Ctnnb1tm1Yy,Tg(Col2a1-cre)1Bhr/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6
Allelic Composition: Ctnnb1tm1Yy/Ctnnb1tm1Yy,Tg(Prnp-GFP/cre)1Blw/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6
Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2(Nfkbia)Rsu/Ctnnb1+,Tg(CMV-cre)1Cgn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6
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MP:0000447 | flattened snout | |
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Allelic Composition: Ctnnb1Bfc/Ctnnb1+ Genetic Background: either: (involves: BALB/cCrl * C3H/HeNCrl) or (involves: BALB/cCrl * C3H/HeNCrl * C57BL/6)
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MP:0000465 | gastrointestinal hemorrhage | "bleeding in the stomach and/or the intestines" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, tc:Teresa Chu , Mouse Genome Informatics Curator, J:60896] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2(Nfkbia)Rsu/Ctnnb1+,Tg(CMV-cre)1Cgn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6
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MP:0000484 | abnormal pulmonary artery morphology | "structrual anomaly of the artery that arises from the right ventricle and conveys unaerated blood to the lungs " [MeSH:National Library of Medicine - Medical Subject Headings, 2003, hdene:Howard Dene, Mouse Genome Informatics Curator] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1tm1Mmt,Shhtm1(EGFP/cre)Cjt/Shh+ Genetic Background: involves: 129X1/SvJ
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MP:0000488 | abnormal intestinal epithelium morphology | "anomalous structure or development of the cellular avascular layer of the digestive tube passing from the stomach to the anus" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Sox10gt/Sox10+ Genetic Background: HYIII/LeJ
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MP:0000490 | abnormal crypts of Lieberkuhn morphology | "malformation or defects in the tubular intestinal glands found in the mucosal membranes" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Sox10gt/Sox10+ Genetic Background: HYIII/LeJ
Allelic Composition: Bmi1tm1(cre/ERT)Mrc/Bmi1+,Ctnnb1tm1Mmt/Ctnnb1+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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MP:0000496 | abnormal small intestine morphology | "structural or developmental anomalies of the intestinum tenue " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2(Nfkbia)Rsu/Ctnnb1+,Tg(CMV-cre)1Cgn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+ Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ
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MP:0000520 | absent kidney | "missing paired organs that excrete urine" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49471] |
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Allelic Composition: Agrnnmf380/Agrnnmf380 Genetic Background: involves: C57BL/6J * CAST
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(Hoxb7-cre)5526Cmb/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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MP:0000527 | abnormal kidney development | "anomalous differentiation of the paired organs responsible for urine secretion" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Agrnnmf380/Agrnnmf380 Genetic Background: involves: C57BL/6J * CAST
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1tm1Mmt,Tcf21tm1(cre)Seq/Tcf21+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tcf21tm1(cre)Seq/Tcf21+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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MP:0000536 | hydroureter | "distention of the ureter with urine, due to blockage from any cause" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:Cml, J:13044] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(Hoxb7-cre)5526Cmb/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1tm1Mmt,Tcf21tm1(cre)Seq/Tcf21+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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MP:0000538 | abnormal urinary bladder morphology | "malformation of the inflatable musculomembranous bag for holding urine" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Msx2-rtTA)885Lma/0,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129 * 129X1/SvJ * C57BL/6
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MP:0000540 | abnormal urinary bladder epithelium morphology | "malformation of the epithelial layer of the urinary bladder" [MGI:tc] |
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Allelic Composition: Faddtm1Wnt/Faddtm1Wnt,Tg(Fadd/EGFP)#Jizh/?,Tg(Mx1-cre)1Cgn/? Genetic Background: involves: 129S4/SvJae * C57BL/6 * CBA
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Upk2-cre)6Xrw/0 Genetic Background: involves: 129X1/SvJ * FVB/N
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Fgfr3tm4Cxd/Fgfr3+,Tg(Upk2-cre)6Xrw/0 Genetic Background: involves: 129S6/SvEvTac * 129X1/SvJ * FVB/N
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MP:0000547 | short limbs | "reduced average length of the extremities" [MGI:CLS, J:61509] |
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Allelic Composition: Psen1tm1Jzt/Psen1tm1Jzt Genetic Background: involves: C57BL/6 * CBA
Allelic Composition: Ctnnb1tm1Yy/Ctnnb1tm1Yy,Tg(Col2a1-cre)1Bhr/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6
Allelic Composition: Ctnnb1tm1Yy/Ctnnb1tm1Yy,Tg(Prnp-GFP/cre)1Blw/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 Genetic Background: involves: 129X1/SvJ * CD-1
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MP:0000550 | abnormal forelimb morphology | "malformation of the entire anterior extremities" [MGI:tc] |
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Allelic Composition: Apoetm1Bres/Apoetm1Bres,Cx3cr1tm1Ifc/Cx3cr1tm1Ifc Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Rac1tm1Djk/Rac1+,Tg(Msx2-cre)5Rem/0 Genetic Background: involves: 129S4/SvJae
Allelic Composition: Ctnnb1tm4Wbm/Ctnnb1tm4Wbm,Tg(Prrx1-cre)98Mlgn/0 Genetic Background: involves: 129P2/OlaHsd
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MP:0000553 | absent radius | "missing the short bone of the lateral forearm" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54637] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(Msx2-cre)5Rem/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
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MP:0000556 | abnormal hindlimb morphology | "malformation of the entire posterior extremities" [MGI:tc] |
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Allelic Composition: Ctnnb1tm4Wbm/Ctnnb1tm4Wbm,Tg(Prrx1-cre)98Mlgn/0 Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Gt(ROSA)26Sortm1(Ctnnb1)Kem/Gt(ROSA)26Sortm1(Ctnnb1)Kem,Tg(Cdx1-cre)23Kem/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * FVB
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Gt(ROSA)26Sortm1(Fgf8)Lma/Gt(ROSA)26Sor+,Tg(Msx2-cre)5Rem/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
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MP:0000557 | absent hindlimb | "missing the entire posterior extremities" [MGI:tc, J:54637] |
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Allelic Composition: Apoetm1Bres/Apoetm1Bres,Cx3cr1tm1Ifc/Cx3cr1tm1Ifc Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Rac1tm1Djk/Rac1+,Tg(Msx2-cre)5Rem/0 Genetic Background: involves: 129S4/SvJae
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Gt(ROSA)26Sortm1(Ctnnb1)Kem/Gt(ROSA)26Sortm1(Ctnnb1)Kem,Tg(Cdx1-cre)23Kem/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * FVB
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(Msx2-cre)5Rem/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
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MP:0000562 | polydactyly | "greater than 5 digits on one or more autopods" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Gt(ROSA)26Sortm2(Sp8)Lma/Gt(ROSA)26Sor+,Sp8tm1Smb/Sp8tm1Smb,Tg(Msx2-cre)5Rem/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
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MP:0000572 | abnormal autopod morphology | "malformation of the hand or foot" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Gt(ROSA)26Sortm1(Fgf8)Lma/Gt(ROSA)26Sor+,Shhtm1(EGFP/cre)Cjt/Shh+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(Msx2-cre)5Rem/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
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MP:0000574 | abnormal foot pad morphology | "anomalous structure of the body of fat on the foot" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0000585 | kinked tail | "a sharp bend or zig-zag in the tail" [J:61295] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2(Nfkbia)Rsu/Ctnnb1+,Tg(CMV-cre)1Cgn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6
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MP:0000627 | abnormal mammary gland morphology | "malformation of the milk-secreting gland that lies within the breast; usually rudimentary in males" [J:70183] |
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Allelic Composition: Slc1a2tm1.1Ncd/Slc1a2tm1.1Ncd,Tg(Pdx1-cre)1Heed/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
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MP:0000653 | abnormal sex gland morphology | "anomalous structure of any of the organized aggregations of cells that function as secretory or excretory organs and are associated with reproduction" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Gt(ROSA)26Sortm1(Ctnnb1)Kem/Gt(ROSA)26Sortm1(Ctnnb1)Kem,Tg(Cdx1-cre)23Kem/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * FVB
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MP:0000674 | abnormal sweat gland morphology | "anomalous structure of any of the coil glands of the skin that secrete sweat" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0000696 | abnormal Peyer s patches morphology | "anomalous structure, development, or cellular make-up of the lymphoid tissue located on the mucosa of the small intestine" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Ctnnb1tm2(Nfkbia)Rsu/Ctnnb1+,Tg(CMV-cre)1Cgn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6
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MP:0000733 | abnormal muscle development | "anomalous differentiation of muscle tissue" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Cd28tm1Mak/Cd28tm1Mak Genetic Background: involves: 129S2/SvPas
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MP:0000745 | tremors | "repetitive, cyclical movements of the body or a body part; usually involuntary, but can also manifest in response to an attempt at movement" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2(Nfkbia)Rsu/Ctnnb1+,Tg(CMV-cre)1Cgn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6
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MP:0000762 | abnormal tongue morphology | "anomalous structure or development of the mobile mass of muscular tissue and surrounding epithelial tissue occupying the cavity of the mouth and forming part of the floor" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Ctnnb1tm1.2Wvv/Ctnnb1tm1.2Wvv Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(KRT14-cre)#Smr/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J
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MP:0000763 | abnormal filiform papillae | "malformed keratinized projections on the dorsal surface of the tongue" [J:45400] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(KRT14-cre)#Smr/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J
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MP:0000774 | reduced brain size | "smaller appearance of the brain" [J:35802] |
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Allelic Composition: Hoxb4tm1Nrm/Hoxb4tm1Nrm Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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MP:0000781 | reduced size of corpus callosum | "smaller commissural plate interconnecting the cortical hemispheres of the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:38857] |
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Allelic Composition: Hoxb13tm2Mrc/Hoxb13tm2Mrc,Hoxd13tm1Mrc/Hoxd13tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0000784 | forebrain hypoplasia | "reduced cell number in the anterior primitive cerebral vesicle; most rostral of three primary vesicles of the embryonic neural tube" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Ctnnb1Bfc/Ctnnb1+ Genetic Background: either: (involves: BALB/cCrl * C3H/HeNCrl) or (involves: BALB/cCrl * C3H/HeNCrl * C57BL/6)
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MP:0000787 | abnormal telencephalon morphology | "any malformation or absence of the paired anteriolateral division of the prosencephalon plus the lamina terminalis from which the olfactory lobes, cerebral cortex, and subcortical nuclei are derived " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,H2afvTg(Wnt1-cre)11Rth/? Genetic Background: involves: 129/Sv * C57BL/6 * CBA
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MP:0000788 | abnormal cerebral cortex morphology | "malformed gray cellular mantle covering the surface of the brain" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:38857] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Emx1tm1(cre)Yql/Emx1+ Genetic Background: B6.129-Emx1tm1(cre)Yql Ctnnb1tm2Kem
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MP:0000807 | abnormal hippocampus morphology | "absent or malformed deep lying structure of the cerebrum involved with memory storage and spatial navigation" [The Atlas of Mouse Development:ISBN 0-12-402035-6, MGI:Cls, J:38857] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Emx1tm1(cre)Yql/Emx1+ Genetic Background: B6.129-Emx1tm1(cre)Yql Ctnnb1tm2Kem
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MP:0000814 | absent dentate gyrus | "lack of the section of the hippocampus normally situated above the gyrus hippocampi and composed of three layers, the molecular, granular, and polymorphic layers" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:59284] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Emx1tm1(cre)Yql/Emx1+ Genetic Background: B6.129-Emx1tm1(cre)Yql Ctnnb1tm2Kem
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MP:0000825 | dilated lateral ventricles | "increase over the normal size of the horseshoe-shaped cavities of the cerebrum" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:38857] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Emx1tm1(cre)Yql/Emx1+ Genetic Background: B6.129-Emx1tm1(cre)Yql Ctnnb1tm2Kem
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MP:0000841 | abnormal hindbrain morphology | "malformed caudal region of the brain; includes cerebellum, pons and medulla oblongata" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:45302] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,H2afvTg(Wnt1-cre)11Rth/? Genetic Background: involves: 129/Sv * C57BL/6 * CBA
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MP:0000850 | absent cerebellum | "missing the part of the metencephalon that lies in the posterior cranial fossa dorsal to the pons and medulla that is concerned with the coordination of movement" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:19212, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,H2afvTg(Wnt1-cre)11Rth/? Genetic Background: involves: 129/Sv * C57BL/6 * CBA
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MP:0000852 | small cerebellum | "reduced size of cerebellum" [MGI:CLS, J:17203, J:67524] |
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Allelic Composition: Hoxb13tm2Mrc/Hoxb13tm2Mrc,Hoxd13tm1Mrc/Hoxd13tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0000854 | abnormal cerebellum development | "malformed or incomplete differentiation of the part of the metencephalon that lies dorsal to the pons and medulla behind the brain stem and controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm3Kba,Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+,H2afvTg(Wnt1-cre)11Rth/0 Genetic Background: involves: 129 * C57BL/6 * CBA/J
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MP:0000897 | abnormal midbrain | "malformation or malfunction associated with the middle of the three cerebral vesicles of the embryo; this region controls sensory and motor functions, including eye movement and coordination of auditory and visual reflexes" [J:23882, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm3Kba,H2afvTg(Wnt1-cre)11Rth/0 Genetic Background: involves: 129 * C57BL/6 * CBA/J
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MP:0000906 | abnormal mesencephalic trigeminal nucleus | "malformation or disorganization of the group of sensory neurons residing in a long, narrow plate in the midbrain; axons pass with the trigeminal nerve" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,H2afvTg(Wnt1-cre)11Rth/? Genetic Background: involves: 129/Sv * C57BL/6 * CBA
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MP:0000913 | abnormal brain development | "malformed or incomplete differentiation of the brain" [MGI:cls, J:49840] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,H2afvTg(Wnt1-cre)11Rth/? Genetic Background: involves: 129/Sv * C57BL/6 * CBA
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MP:0000929 | open neural tube | "incomplete invagination and fusion of the neuroepithelial layer in early development" [MGI:CLS, J:53370, J:62571] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Gt(ROSA)26Sortm1(Ctnnb1)Kem/Gt(ROSA)26Sortm1(Ctnnb1)Kem,Tg(Cdx1-cre)23Kem/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * FVB
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MP:0000934 | abnormal telencephalon development | "malformed or incomplete differentiation of the anterior division of the embryonic prosencephalon " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:49840] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,H2afvTg(Wnt1-cre)11Rth/0 Genetic Background: involves: 129 * C57BL/6 * CBA/J
Allelic Composition: Apctm1Rak/Apc+,Ctnnb1tm1.2Wvv/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
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MP:0000936 | small telencephalic vesicles | "reduced size of the paired diverticula of the telencephalon, from which the forebrain develops" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:49840] |
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Allelic Composition: Ctnnb1tm1Max/Ctnnb1+,Hesx1tm1(cre)Jpmb/Hesx1tm1Icar Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * 129S1/Sv * 129X1/SvJ
Allelic Composition: Ctnnb1tm1Max/Ctnnb1tm2Kem,Hesx1tm1(cre)Jpmb/Hesx1tm1Icar Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1+,Hesx1tm1(cre)Jpmb/Hesx1tm1Icar Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * 129S1/Sv * 129X1/SvJ
Allelic Composition: Ctnnb1tm1Max/Ctnnb1+,Hesx1tm1Icar/Hesx1tm1Icar Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ
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MP:0000939 | reduced motor neuron number | "fewer than normal numbers of cells that innervate an effector (muscle or glandular) tissue" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Olig2tm1(cre)Tmj/Olig2+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Juptm1Ruiz/Juptm1Ruiz,Olig2tm1(cre)Tmj/Olig2+ Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ
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MP:0000956 | reduced spinal cord size | "smaller appearance of the spinal cord" [J:35802] |
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Allelic Composition: Hoxb4tm1Nrm/Hoxb4tm1Nrm Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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MP:0000961 | abnormal dorsal root ganglia morphology | "malformed group of nerve cell bodies of each segmental nerve projecting from the spinal cord " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:60159] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,H2afvTg(Wnt1-cre)11Rth/? Genetic Background: involves: 129/Sv * C57BL/6 * CBA
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MP:0001056 | abnormal cranial nerve morphology | "any anomaly, deformity, or malformation of any of the twelve nerves that emerge from the cranium as opposed to the spinal nerves" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:45302] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,H2afvTg(Wnt1-cre)11Rth/? Genetic Background: involves: 129/Sv * C57BL/6 * CBA
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MP:0001062 | absent oculomotor nerve | "missing nerve of the extraocular muscles, iris and ciliary body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:19212] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,H2afvTg(Wnt1-cre)11Rth/? Genetic Background: involves: 129/Sv * C57BL/6 * CBA
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MP:0001071 | abnormal facial nerve morphology | "malformed or misprojection of motor axons from the pons to the face" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:29973] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,H2afvTg(Wnt1-cre)11Rth/? Genetic Background: involves: 129/Sv * C57BL/6 * CBA
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MP:0001073 | abnormal glossopharyngeal nerve morphology | "malformed or misprojection of sensory and autonomic axons to the parotid gland, carotid body, posterior third of the tongue" [Principles of Neural Science:ISBN 0-8385-8034-3, J:33038] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,H2afvTg(Wnt1-cre)11Rth/? Genetic Background: involves: 129/Sv * C57BL/6 * CBA
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MP:0001074 | abnormal vagus nerve morphology | "malformed or misprojection of autonomic, sensory and motor axons of the tenth cranial nerve to the pharynx, larynx, trachea, lungs, heart and GI tract" [Principles of Neural Science:ISBN 0-8385-8034-3, J:33038] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,H2afvTg(Wnt1-cre)11Rth/? Genetic Background: involves: 129/Sv * C57BL/6 * CBA
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MP:0001076 | abnormal hypoglossal nerve morphology | "malformation or misprojection of motor axons to the tongue" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:45302] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,H2afvTg(Wnt1-cre)11Rth/? Genetic Background: involves: 129/Sv * C57BL/6 * CBA
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MP:0001154 | seminiferous tubule degeneration | "a retrogressive impairment of function or destruction of the tubules in the testes where spermatogenesis occurs" [J:50844] |
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Allelic Composition: Amhr2tm3(cre)Bhr/Amhr2+,Ctnnb1tm1Mmt/Ctnnb1+,Ptentm1Hwu/Ptentm1Hwu Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ
Allelic Composition: Amhr2tm3(cre)Bhr/Amhr2+,Ctnnb1tm1Mmt/Ctnnb1+ Genetic Background: involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Krastm4Tyj/Kras+,Amhr2tm3(cre)Bhr/Amhr2+ Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
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MP:0001176 | abnormal lung development | "malformation or arrest of differentiation of the organs of respiration" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931] |
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Allelic Composition: Hunktm1Lach/Hunk+,Tg(MMTV-Myc)#Led/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * CD-1
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1tm1Mmt,Shhtm1(EGFP/cre)Cjt/Shh+ Genetic Background: involves: 129X1/SvJ
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MP:0001181 | absent lungs | "missing organs of respiration" [J:51966, J:50768] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Shhtm1(EGFP/cre)Cjt/Shh+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1tm1Mmt,Shhtm1(EGFP/cre)Cjt/Shh+ Genetic Background: involves: 129X1/SvJ
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MP:0001212 | skin lesions | "focal patches of inflammation on the skin" [J:30162] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Gt(ROSA)26Sortm1(Ctnnb1)Kem/Gt(ROSA)26Sor+,Tg(Foxn1-cre)1Tbo/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6
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MP:0001216 | abnormal epidermal layer morphology | "anomalous structure or development of the superficial epithelial portion of the skin" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(KRT5-rtTA)#Glk/0,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(KRT14-cre/ERT)20Efu/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1
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MP:0001219 | thickened epidermis | "increase in the width of the epidermal cell layer in the skin" [J:65146] |
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Allelic Composition: Onecut1tm1.1Mga/Onecut1tm1.1Mga,Tg(Pdx1-cre)89.1Dam/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * CBA * SJL
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(KRT5-rtTA)#Glk/0,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N
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MP:0001265 | reduced body size | "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170] |
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Allelic Composition: Rxfp1tm1Aia/Rxfp1tm1Aia,Tg(Ins2-Insl3)4Imad/0 Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2(Nfkbia)Rsu/Ctnnb1+,Tg(CMV-cre)1Cgn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6
Allelic Composition: Ctnnb1tm4Wbm/Ctnnb1tm4Wbm,Tg(Pdx1-cre)6Tuv/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Gt(ROSA)26Sortm1(Ctnnb1)Kem/Gt(ROSA)26Sortm1(Ctnnb1)Kem,Tg(Foxn1-cre)1Tbo/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Gt(ROSA)26Sortm1(Ctnnb1)Kem/Gt(ROSA)26Sor+,Tg(Foxn1-cre)1Tbo/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6
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MP:0001272 | increased metastatic potential | |
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Allelic Composition: Amhr2tm3(cre)Bhr/Amhr2+,Ctnnb1tm1Mmt/Ctnnb1+,Ptentm1Hwu/Ptentm1Hwu Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ
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MP:0001280 | loss of vibrissae | "inability to retain the whiskers" [J:45400] |
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Allelic Composition: Apctm3Mmt/Apc+ Genetic Background: involves: 129X1/SvJ * C57BL/6N
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MP:0001283 | sparse vibrissae | "few and widely spaced whiskers" [J:65302] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2(Nfkbia)Rsu/Ctnnb1+,Tg(CMV-cre)1Cgn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6
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MP:0001284 | absent vibrissae | "missing whiskers" [J:18378] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Tcfap2a-cre)1Will/0 Genetic Background: involves: 129X1/SvJ * C57BL/6
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MP:0001293 | anophthalmia | "congenital absence of all tissues of the eyes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CML, J:71979] |
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Allelic Composition: Ctnnb1Bfc/Ctnnb1+ Genetic Background: either: (involves: BALB/cCrl * C3H/HeNCrl) or (involves: BALB/cCrl * C3H/HeNCrl * C57BL/6)
Allelic Composition: Ctnnb1tm1Max/Ctnnb1+,Hesx1tm1(cre)Jpmb/Hesx1tm1Icar Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * 129S1/Sv * 129X1/SvJ
Allelic Composition: Ctnnb1tm1Max/Ctnnb1tm2Kem,Hesx1tm1(cre)Jpmb/Hesx1tm1Icar Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1+,Hesx1tm1(cre)Jpmb/Hesx1tm1Icar Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * 129S1/Sv * 129X1/SvJ
Allelic Composition: Ctnnb1tm1Max/Ctnnb1+,Hesx1tm1Icar/Hesx1tm1Icar Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ
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MP:0001297 | microphthalmia | "reduced average size of the eyes" [J:18048] |
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Allelic Composition: Apctm3Mmt/Apc+ Genetic Background: involves: 129X1/SvJ * C57BL/6N
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1tm1Mmt,Tg(Cryaa-cre)10Mlr/0 Genetic Background: involves: 129X1/SvJ * FVB/N
Allelic Composition: Ctnnb1Bfc/Ctnnb1+ Genetic Background: either: (involves: BALB/cCrl * C3H/HeNCrl) or (involves: BALB/cCrl * C3H/HeNCrl * C57BL/6)
Allelic Composition: Ctnnb1tm1Max/Ctnnb1+,Hesx1tm1(cre)Jpmb/Hesx1tm1Icar Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * 129S1/Sv * 129X1/SvJ
Allelic Composition: Ctnnb1tm1Max/Ctnnb1tm2Kem,Hesx1tm1(cre)Jpmb/Hesx1tm1Icar Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1+,Hesx1tm1(cre)Jpmb/Hesx1tm1Icar Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * 129S1/Sv * 129X1/SvJ
Allelic Composition: Ctnnb1tm1Max/Ctnnb1+,Hesx1tm1Icar/Hesx1tm1Icar Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ
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MP:0001300 | ocular hypertelorism | "increased distance between the eyes " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Hoxb13tm2Mrc/Hoxb13tm2Mrc,Hoxd13tm1Mrc/Hoxd13tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0001304 | cataracts | "complete or partial opacity of the lens" [J:65031] |
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Allelic Composition: Ctnnb1Bfc/Ctnnb1+ Genetic Background: either: (involves: BALB/cCrl * C3H/HeNCrl) or (involves: BALB/cCrl * C3H/HeNCrl * C57BL/6)
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MP:0001306 | small lens | "reduced size of the transparent structure of the eye responsible for focusing light rays" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840] |
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Allelic Composition: Apctm3Mmt/Apc+ Genetic Background: involves: 129X1/SvJ * C57BL/6N
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MP:0001337 | dry eyes | "absence of natural or normal moisture in the eye" [J:53284] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2(Nfkbia)Rsu/Ctnnb1+,Tg(CMV-cre)1Cgn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6
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MP:0001340 | abnormal eyelid morphology | "malformation of the skin folds covering the front of the eyeball" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ctnnb1tm2(Nfkbia)Rsu/Ctnnb1+,Tg(CMV-cre)1Cgn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6
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MP:0001341 | absent eyelids | "missing skin folds covering the front of the eyeball when closed" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61790] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Tcfap2a-cre)1Will/0 Genetic Background: involves: 129X1/SvJ * C57BL/6
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MP:0001363 | increased anxiety-related response | "when compared to controls, subjects exhibit more responses thought to be indicative of anxiety in behavioral tests" [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator, J:49752, J:53060] |
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Allelic Composition: Ptentm1Mro/Pten+,Sdhbtm1.1Ics/Sdhb+,Tg(KLK3-cre)D4Trp/0 Genetic Background: involves: 129S2/SvPas * FVB
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MP:0001382 | abnormal nursing | "females do not nurse pups or nurse pups infrequently" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Rxfp1tm1Aia/Rxfp1tm1Aia,Tg(Ins2-Insl3)4Imad/0 Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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MP:0001405 | impaired coordination | "reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Hoxb13tm2Mrc/Hoxb13tm2Mrc,Hoxd13tm1Mrc/Hoxd13tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0001408 | stereotypic behavior | "repetitive, invariant, perseverative motor patterns that do not appear to be purposeful" [What s wrong with my mouse?:ISBN 0-471-31639-3] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Pvalbtm1(cre)Arbr/Pvalb+ Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0001436 | abnormal suckling behavior | "reduced ability or inability to exert suction by the mouth, or atypical suckling pattern" [J:16461] |
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Allelic Composition: Apoetm1Bres/Apoetm1Bres,Cx3cr1tm1Ifc/Cx3cr1tm1Ifc Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
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MP:0001441 | increased grooming behavior | "increased amount of time spent cleaning and/or keeping outward appearance tidy (self, mate or offspring)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Pvalbtm1(cre)Arbr/Pvalb+ Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0001447 | abnormal nest building behavior | "deviation from the usual behavior of mice to build sleeping nests out of any available materials; also of female mice to bulid nests to protect offspring" [J:42758, What s wrong with my mouse?:ISBN 0-471-31639-3] |
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Allelic Composition: Ptentm1Mro/Pten+,Sdhbtm1.1Ics/Sdhb+,Tg(KLK3-cre)D4Trp/0 Genetic Background: involves: 129S2/SvPas * FVB
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MP:0001473 | reduced long term potentiation | "less than the normal persistent robust synaptic response induced by synchronous stimulation of pre- and postsynaptic cells " [Principles of Neural Science:ISBN 0-8385-8034-3] |
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Allelic Composition: Hoxb13tm2Mrc/Hoxb13tm2Mrc,Hoxd13tm1Mrc/Hoxd13tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0001505 | hunched posture | "stooped low with the limbs pulled in close to the body and arched back" [J:67231, J:30404] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2(Nfkbia)Rsu/Ctnnb1+,Tg(CMV-cre)1Cgn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6
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MP:0001510 | abnormal coat appearance | "coat that looks different from the usual state " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0001525 | impaired balance | "reduced ability of an animal to maintain equilibrium" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:64962, J:17123] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0001529 | abnormal vocalization | "an inability, decreased ability or altered ability to produce sound from the vocal organs; or a general increase or decrease in the production of vocal sound" [cml:Cathleen M. Lutz , Mouse Genome Informatics Curator, J:85479] |
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Allelic Composition: Hoxb13tm2Mrc/Hoxb13tm2Mrc,Hoxd13tm1Mrc/Hoxd13tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0001541 | abnormal osteoclast function | "reduced ability or inability of osteoclasts to absorb and remove osseous tissue" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58795] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Ppargtm1.1(tTA)Jmgr/Pparg+,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1+,Ppargtm1.1(tTA)Jmgr/Pparg+,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0001577 | anemia | "less than normal levels of red blood cells, hemoglobin or volume of packed red blood cells " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:53370] |
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Allelic Composition: Amhr2tm3(cre)Bhr/Amhr2+,Ctnnb1tm1Mmt/Ctnnb1+,Ptentm1Hwu/Ptentm1Hwu Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ
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MP:0001614 | abnormal vasculature | "anomalies in the structure of development of the network of tubes that carries blood through the body" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Sox9tm1Gsr/Sox9+,Tg(Col2a1-cre)1Bhr/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * SJL
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1+,Ptentm1Hwu/Ptentm1Hwu,Tg(Cdh5-cre)7Mlia/0 Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * BALB/c * C57BL/6 * FVB/N
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MP:0001622 | abnormal vasculogenesis | "aberrant process of the initial establishment of the vascular network " [J:67296, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Edil3Tg(Sox2-cre)1Amc/Edil3+,Wnt7atm1Amc/Wnt7atm1Amc,Wnt7btm1Parr/Wnt7btm2Amc Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
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MP:0001674 | abnormal triploblastic development | "abnormal development of the three primary germ layers" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, tc:Teresa Chu , Mouse Genome Informatics Curator] |
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Allelic Composition: Prrx1tm1Tex/Prrx1tm1Tex,Prrx2tm1Hubr/Prrx2tm1Hubr Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB
Allelic Composition: Ctnnb1tm1Wbm/Ctnnb1tm1Wbm Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2Wbm/Ctnnb1tm2Wbm Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm3Wbm/Ctnnb1tm3Wbm Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Gt(ROSA)26Sortm1(Ctnnb1)Kem/Gt(ROSA)26Sor+,Tg(Zp3-cre)93Knw/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6J
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Gt(ROSA)26Sortm1(Ctnnb1)Kem/Gt(ROSA)26Sortm1.1(Ctnnb1)Kem,Edil3Tg(Sox2-cre)1Amc/Edil3+ Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * CBA
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MP:0001675 | abnormal ectoderm development | "failure or abnormality in the formation of the ectoderm during gastrulation" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ctnnb1tm1Wbm/Ctnnb1tm1Wbm Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2Wbm/Ctnnb1tm2Wbm Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm3Wbm/Ctnnb1tm3Wbm Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0001676 | abnormal apical ectodermal ridge | "malformation of the multilayered ectodermal region at the tip of a limb bud necessary for the proper development of the underlying mesenchyme" [MGI:tc] |
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Allelic Composition: Apoetm1Bres/Apoetm1Bres,Cx3cr1tm1Ifc/Cx3cr1tm1Ifc Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
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MP:0001680 | abnormal mesoderm development | "failure or abnormality in the formation of the mesoderm during gastrulation" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ctnnb1tm1Wbm/Ctnnb1tm1Wbm Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2Wbm/Ctnnb1tm2Wbm Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm3Wbm/Ctnnb1tm3Wbm Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2.1Kem/Ctnnb1+,Sall4Gt(W097E01)Flo/Sall4+ Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6
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MP:0001683 | absent mesoderm | "missing or failure to differentiate the middle primary germ layer " [J:40594] |
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Allelic Composition: Scn8amed-J/Scn8amed-J,Scnm1s/Scnm1s Genetic Background: involves: C57BL/6J
Allelic Composition: Ctnnb1tm1Wbm/Ctnnb1tm1Wbm Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2Wbm/Ctnnb1tm2Wbm Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm3Wbm/Ctnnb1tm3Wbm Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2Kba/Ctnnb1tm2Kba Genetic Background: involves: 129S6/SvEvTac * C57BL/6
Allelic Composition: Ctnnb1tm3Kba/Ctnnb1tm3Kba Genetic Background: involves: 129S6/SvEvTac * C57BL/6
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MP:0001684 | abnormal axial mesoderm | "malformed middle primary germ layer" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:51834] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Tg(T-cre/ERT2)1Lwd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H/HeNcr * C57BL/6NCr
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MP:0001688 | abnormal somite development | "anomalous formation of any of the paired, metamerically arranged cell masses formed in the embryonic paraxial mesoderm" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Arpc3tm1Ssod/Arpc3tm1Ssod,Gt(ROSA)26Sortm2(CAG-tdTomato)Fawa/Gt(ROSA)26Sor+,Tg(Thy1-cre/ERT2,-EYFP)VGfng/0 Genetic Background: involves: C57BL/6 * SJL
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Tg(T-cre/ERT2)1Lwd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H/HeNcr * C57BL/6NCr
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MP:0001695 | abnormal gastrulation | "anomalous development and invagination of the embryonic germ layers" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Cacna1ctm2Hfm/Cacna1ctm2Hfm Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Ctnnb1tm2Wbm/Ctnnb1tm2Wbm Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm3Wbm/Ctnnb1tm3Wbm Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2Kba/Ctnnb1tm2Kba Genetic Background: involves: 129S6/SvEvTac * C57BL/6
Allelic Composition: Ctnnb1tm3Kba/Ctnnb1tm3Kba Genetic Background: involves: 129S6/SvEvTac * C57BL/6
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MP:0001696 | failure to gastrulate | "inability to differentiate and invaginate the primary germ layers" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:34458] |
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Allelic Composition: Ctnnb1tm1Wbm/Ctnnb1tm1Wbm Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2Wbm/Ctnnb1tm2Wbm Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm3Wbm/Ctnnb1tm3Wbm Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Gt(ROSA)26Sortm1(Ctnnb1)Kem/Gt(ROSA)26Sor+,Tg(Zp3-cre)93Knw/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6J
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Gt(ROSA)26Sortm1(Ctnnb1)Kem/Gt(ROSA)26Sortm1.1(Ctnnb1)Kem,Edil3Tg(Sox2-cre)1Amc/Edil3+ Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * CBA
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MP:0001698 | reduced embryo size | "smaller proportions of embryo compared to littermates" [J:61790] |
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Allelic Composition: Prrx1tm1Tex/Prrx1tm1Tex,Prrx2tm1Hubr/Prrx2tm1Hubr Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB
Allelic Composition: Ctnnb1tm1Wbm/Ctnnb1tm1Wbm Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2Wbm/Ctnnb1tm2Wbm Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm3Wbm/Ctnnb1tm3Wbm Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm1Kba/Ctnnb1tm1Kba Genetic Background: involves: 129S6/SvEvTac * C57BL/6
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MP:0001705 | abnormal proximal-distal axis patterning | "anomaly in the formation or development of a body structure, often a limb, in relation to the structure s proximity to the trunk or point of origin" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Ctnnb1tm1Wbm/Ctnnb1tm1Wbm Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2Wbm/Ctnnb1tm2Wbm Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm3Wbm/Ctnnb1tm3Wbm Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0001710 | absent amniotic folds | "failure of amnion to form involutions" [J:40594] |
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Allelic Composition: Prrx1tm1Tex/Prrx1tm1Tex,Prrx2tm1Hubr/Prrx2tm1Hubr Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB
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MP:0001711 | abnormal placenta | |
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Allelic Composition: Sox9tm1Gsr/Sox9+,Tg(Col2a1-cre)1Bhr/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * SJL
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MP:0001718 | abnormal yolk sac | "malformed extraembryonic tissue which contributes to hematopoietic circulation" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:12623] |
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Allelic Composition: Sox9tm1Gsr/Sox9+,Tg(Col2a1-cre)1Bhr/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * SJL
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MP:0001722 | pale yolk sac | "bloodless yolk sac" [J:62571] |
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Allelic Composition: Sox9tm1Gsr/Sox9+,Tg(Col2a1-cre)1Bhr/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * SJL
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MP:0001750 | increased circulating follicle stimulating hormone level | "higher than normal levels in the blood stream of FSH, the hormone that, in females, stimulates the graafian follicles of the ovary and assists in follicular maturation and the secretion of estradiol; in the male it stimulates the epithelium of the seminiferous tubules and is partly responsible for spermatogenesis " [J:35782, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Krastm4Tyj/Kras+,Tg(CYP19A1-cre)1Jri/0 Genetic Background: involves: 129S4/SvJae * 129X1/SvJ * C57BL/6
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Ptentm1Hwu/Ptentm1Hwu,Tg(CYP19A1-cre)1Jri/0 Genetic Background: involves: 129S4/SvJae * 129X1/SvJ * C57BL/6
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MP:0001751 | increased circulating luteinizing hormone level | "higher than the normal levels in the bloodstream of LH, the hormone that regulates steroid production by the interstitial cells of the testis and the ovary" [J:35782, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Krastm4Tyj/Kras+,Tg(CYP19A1-cre)1Jri/0 Genetic Background: involves: 129S4/SvJae * 129X1/SvJ * C57BL/6
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Ptentm1Hwu/Ptentm1Hwu,Tg(CYP19A1-cre)1Jri/0 Genetic Background: involves: 129S4/SvJae * 129X1/SvJ * C57BL/6
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MP:0001787 | pericardial edema | "accumulation of watery fluid in the pericardial sac of the heart" [J:52597] |
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Allelic Composition: Sox9tm1Gsr/Sox9+,Tg(Col2a1-cre)1Bhr/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * SJL
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MP:0001846 | increased inflammatory response | "greater than expected response to injury, infection, or insult " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2(Nfkbia)Rsu/Ctnnb1+,Tg(CMV-cre)1Cgn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6
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MP:0001850 | otitis media | "middle ear inflammation" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60896] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2(Nfkbia)Rsu/Ctnnb1+,Tg(CMV-cre)1Cgn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6
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MP:0001852 | conjunctivitis | "inflammation of the mucous membrane that lines the inner surface of the eyelids" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60896] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0001869 | pancreas inflammation | "local accumulation of fluid, plasma proteins, and leukocytes in the pancreas " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7] |
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Allelic Composition: Ctnnb1tm4Wbm/Ctnnb1tm4Wbm,Tg(Pdx1-cre)6Tuv/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
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MP:0001884 | mammary alveolar hyperplasia | |
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Allelic Composition: Slc1a2tm1.1Ncd/Slc1a2tm1.1Ncd,Tg(Pdx1-cre)1Heed/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
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MP:0001914 | hemorrhage | "loss of blood from the vascular compartment to the exterior or into nonvascular body space as a result of rupture or severance of the blood vessels" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Sox9tm1Gsr/Sox9+,Tg(Col2a1-cre)1Bhr/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * SJL
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MP:0001915 | intracranial hemorrhage | "bleeding within the skull, including hemorrhage into the brain and within the cranial epidural, subdural, and subarachnoid spaces" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Edil3Tg(Sox2-cre)1Amc/Edil3+,Wnt7atm1Amc/Wnt7atm1Amc,Wnt7btm1Parr/Wnt7btm2Amc Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
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MP:0001925 | male infertility | "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409] |
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Allelic Composition: Rxfp1tm1Aia/Rxfp1tm1Aia,Tg(Ins2-Insl3)4Imad/0 Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Amhr2tm3(cre)Bhr/Amhr2+,Ctnnb1tm1Mmt/Ctnnb1+ Genetic Background: involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
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MP:0001935 | reduced litter size | "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2(Nfkbia)Rsu/Ctnnb1+,Tg(CMV-cre)1Cgn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6
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MP:0001944 | abnormal pancreas morphology | "malformation of the organ that secretes pancreatic juice into the duodenum and secretes glucagon and insulin into the bloodstream" [il:Ira Lu , Mouse Genome Informatics Curator] |
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Allelic Composition: Ctnnb1tm4Wbm/Ctnnb1tm4Wbm,Tg(Pdx1-cre)6Tuv/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
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MP:0001967 | deafness | "inability to hear" [J:57651] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2(Nfkbia)Rsu/Ctnnb1+,Tg(CMV-cre)1Cgn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6
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MP:0002001 | blindness | "loss of the sense of sight" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2(Nfkbia)Rsu/Ctnnb1+,Tg(CMV-cre)1Cgn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6
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MP:0002020 | increased tumor incidence | "greater than average number of tumors, usually a specific type" [MGI:cls, J:34193] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1tm1Mmt,Tcf21tm1(cre)Seq/Tcf21+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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MP:0002052 | decreased tumor incidence | "less than the expected number of abnormal growths in a specific population" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Apctm1Tno/Apctm1Tno,Ctnnb1tm4.1Wbm/Ctnnb1+ Genetic Background: involves: 129/Sv * 129P2/OlaHsd * 129S4/SvJae * C57BL/6
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MP:0002058 | neonatal lethality | "death of animal within one day after birth" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1tm1Mmt,Osr2tm5(cre)Jian/Osr2+ Genetic Background: involves: 129X1/SvJ
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1+,Osr2tm2(cre)Jian/Osr2+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1tm1Mmt,Tcf21tm1(cre)Seq/Tcf21+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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MP:0002064 | seizures | "sudden and often acute manifestation of epileptic attack, sometimes convulsive" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Rxfp1tm1Aia/Rxfp1tm1Aia,Tg(Ins2-Insl3)4Imad/0 Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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MP:0002073 | abnormal hair growth | "absence or reduced amount of hair or abnormal onset of hair growth cycle or development" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Hoxb4tm1Nrm/Hoxb4tm1Nrm Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Ctnnb1tm4Wbm/Ctnnb1tm4Wbm,Krt14tm1.1(cre)Wbm/Krt14+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2(Nfkbia)Rsu/Ctnnb1+,Tg(CMV-cre)1Cgn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(KRT5-rtTA)#Glk/0,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(Krt1-15-cre/PGR)22Cot/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
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MP:0002080 | prenatal lethality | "death anytime between fertilization and E18.5" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1tm1Mmt,Tcf21tm1(cre)Seq/Tcf21+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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MP:0002083 | premature death | "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Pou3f4-cre)32Cren/? Genetic Background: involves: 129X1/SvJ
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Fabp1-cre)1Mmt/? Genetic Background: involves: 129X1/SvJ
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1tm1Mmt,Tg(Mx1-cre)1Cgn/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Mx1-cre)1Cgn/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA
Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm4Wbm/Ctnnb1tm4Wbm,Tg(Pdx1-cre)6Tuv/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
Allelic Composition: Bmi1tm1(cre/ERT)Mrc/Bmi1+,Ctnnb1tm1Mmt/Ctnnb1+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+,Prom1tm1(cre/ERT2)Gilb/Prom1+ Genetic Background: involves: 129S6/SvEvTac * 129X1/SvJ
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Krastm1Bbd/Kras+,Tg(Pbsn-cre)4Prb/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Pbsn-cre)4Prb/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * DBA/2
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1+,Ptentm1Hwu/Ptentm1Hwu,Tg(Cdh5-cre)7Mlia/0 Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * BALB/c * C57BL/6 * FVB/N
Allelic Composition: Amhr2tm3(cre)Bhr/Amhr2+,Ctnnb1tm1Mmt/Ctnnb1+,Ptentm1Hwu/Ptentm1Hwu Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1tm1Mmt,Ptentm1Hwu/Ptentm1Hwu,Tg(Upk2-cre)6Xrw/0 Genetic Background: involves: 129S4/SvJae * 129X1/SvJ * FVB/N
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Ptentm1Hwu/Ptentm1Hwu,Tg(Upk2-cre)6Xrw/0 Genetic Background: involves: 129S4/SvJae * 129X1/SvJ * FVB/N
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Fgfr3tm4Cxd/Fgfr3+,Tg(Upk2-cre)6Xrw/0 Genetic Background: involves: 129S6/SvEvTac * 129X1/SvJ * FVB/N
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(CYP19A1-cre)1Jri/0 Genetic Background: involves: 129X1/SvJ * C57BL/6
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Krastm4Tyj/Kras+,Tg(CYP19A1-cre)1Jri/0 Genetic Background: involves: 129S4/SvJae * 129X1/SvJ * C57BL/6
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Ptentm1Hwu/Ptentm1Hwu,Tg(CYP19A1-cre)1Jri/0 Genetic Background: involves: 129S4/SvJae * 129X1/SvJ * C57BL/6
Allelic Composition: Bmpr1atm2.1Bhr/Bmpr1atm2.1Bhr,Ctnnb1tm1Mmt/Ctnnb1+,Krt14tm1.1(cre)Wbm/Krt14+ Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * 129X1/SvJ
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Msx2-rtTA)885Lma/0,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129 * 129X1/SvJ * C57BL/6
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1tm1Mmt,Tg(Upk2-cre)6Xrw/0,Tg(Upk2-HRAS*Q61L)5Xrw/0 Genetic Background: involves: 129X1/SvJ * FVB/N
Allelic Composition: Cdkn1atm1Led/Cdkn1atm1Led,Ctnnb1tm1Mmt/Ctnnb1tm1Mmt,Tg(Upk2-cre)6Xrw/0 Genetic Background: involves: 129S6/SvEvTac * 129X1/SvJ * FVB/N
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1tm1Mmt,Krastm4Tyj/Kras+,Tg(Upk2-cre)6Xrw/0 Genetic Background: involves: 129S4/SvJae * 129X1/SvJ * FVB/N
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MP:0002084 | abnormal developmental patterning | "abnormal systematic arrangement of the developing body along an axis" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Cacna1ctm2Hfm/Cacna1ctm2Hfm Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Ctnnb1tm2Wbm/Ctnnb1tm2Wbm Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm3Wbm/Ctnnb1tm3Wbm Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0002085 | abnormal embryonic tissue morphology | "structural abnormality or development of any embryonic tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Arntltm1.1Ljm/Arntltm1.1Ljm,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: C57BL/6 * FVB/N
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Gt(ROSA)26Sortm1(Ctnnb1)Kem/Gt(ROSA)26Sortm1.1(Ctnnb1)Kem,Edil3Tg(Sox2-cre)1Amc/Edil3+ Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * CBA
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Edil3Tg(Sox2-cre)1Amc/Edil3+ Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * CBA
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Tg(Zp3-cre)93Knw/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6J
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MP:0002086 | abnormal extraembryonic tissue morphology | "structural abnormality or development of the membranes involved with embryonic protection and nutrition" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:40594, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Prrx1tm1Tex/Prrx1tm1Tex,Prrx2tm1Hubr/Prrx2tm1Hubr Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB
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MP:0002092 | abnormal eye morphology | "abnormal development of the eye tissues resulting in morphological abnormality or abnormal structure of the visual system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2(Nfkbia)Rsu/Ctnnb1+,Tg(CMV-cre)1Cgn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Tcfap2a-cre)1Will/0 Genetic Background: involves: 129X1/SvJ * C57BL/6
Allelic Composition: Ctnnb1Bfc/Ctnnb1+ Genetic Background: either: (involves: BALB/cCrl * C3H/HeNCrl) or (involves: BALB/cCrl * C3H/HeNCrl * C57BL/6)
Allelic Composition: Ctnnb1Bfc/Ctnnb1+,Dkk1tm1Lmgd/Dkk1+ Genetic Background: either: (involves: 129/Sv * BALB/cCrl * C3H/HeNCrl) or (involves: 129/Sv * BALB/cCrl * C3H/HeNCrl * C57BL/6)
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MP:0002110 | abnormal digit morphology | "abnormal development of the digits resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Gt(ROSA)26Sortm1(Ctnnb1)Kem/Gt(ROSA)26Sortm1(Ctnnb1)Kem,Tg(Cdx1-cre)23Kem/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * FVB
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MP:0002116 | abnormal craniofacial bone morphology | "abnormal development of cranial or facial bones resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Psen1tm1Jzt/Psen1tm1Jzt Genetic Background: involves: C57BL/6 * CBA
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm3Kba,Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+,H2afvTg(Wnt1-cre)11Rth/0 Genetic Background: involves: 129 * C57BL/6 * CBA/J
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MP:0002123 | abnormal hematopoiesis | "abnormal development of the enucleated fetal and adult erythrocytes that develop in the aorta, genital ridge and mesonephros region and later in the fetal and adult liver" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1+,Ptentm1Hwu/Ptentm1Hwu,Tg(Cdh5-cre)7Mlia/0 Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * BALB/c * C57BL/6 * FVB/N
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MP:0002135 | abnormal kidney morphology | "abnormal development of the kidney resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Dysfprmd/Dysfprmd,Hprttm2(CAG-Myof)Isrd/Hprttm2(CAG-Myof)Isrd Genetic Background: involves: 129 * A/J * C57BL/6
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MP:0002151 | abnormal neural tube morphology/development | "anomalous structure of or development of the embryonic neural tube resulting in structural anomaly" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,H2afvTg(Wnt1-cre)11Rth/? Genetic Background: involves: 129/Sv * C57BL/6 * CBA
Allelic Composition: Ctnnb1tm4Wbm/Ctnnb1tm4Wbm,Pax3tm1(cre)Joe/Pax3+ Genetic Background: Not Specified
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,H2afvTg(Wnt1-cre)11Rth/0 Genetic Background: involves: 129 * C57BL/6 * CBA/J
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Gt(ROSA)26Sortm1(Ctnnb1)Kem/Gt(ROSA)26Sortm1(Ctnnb1)Kem,Tg(Cdx1-cre)23Kem/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * FVB
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MP:0002152 | abnormal brain morphology | "anomalous structure of or abnormal development of the brain, one of the two components of the central nervous system and the center of thought and emotion; controls coordination, bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, http://cancerweb.ncl.ac.uk] |
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Allelic Composition: Hoxb4tm1Nrm/Hoxb4tm1Nrm Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Pou3f4-cre)32Cren/? Genetic Background: involves: 129X1/SvJ
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,H2afvTg(Wnt1-cre)11Rth/? Genetic Background: involves: 129/Sv * C57BL/6 * CBA
Allelic Composition: Axin1tm4Cos/Axin1tm4Cos,Ctnnb1tm2.1Kem/Ctnnb1+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Gt(ROSA)26Sortm1(Ctnnb1)Kem/Gt(ROSA)26Sor+,H2afvTg(Wnt1-cre)11Rth/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6J * CBA/J
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MP:0002169 | no phenotype detected | "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Hey2tm1Uts/Hey2tm1Uts Genetic Background: either: (involves: 129X1/SvJ) or (involves: C57BL/6)
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+ Genetic Background: involves: 129X1/SvJ
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MP:0002188 | small heart | "reduced size of the heart relative to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:67044] |
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Allelic Composition: Sox9tm1Gsr/Sox9+,Tg(Col2a1-cre)1Bhr/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * SJL
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MP:0002196 | acallosal | "absence of the commissural plate interconnecting the cortical hemispheres of the brain" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Emx1tm1(cre)Yql/Emx1+ Genetic Background: B6.129-Emx1tm1(cre)Yql Ctnnb1tm2Kem
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MP:0002210 | abnormal sex determination | "anomaly of primary or secondary sexual development or characteristics" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Wnt4tm1.2Bhr/Wnt4tm1.2Bhr Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6J
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MP:0002233 | abnormal nose morphology | "any structural anomaly of the organ that is specialized for smell and is part of the respiratory system " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Axin1tm4Cos/Axin1tm4Cos,Ctnnb1tm2.1Kem/Ctnnb1+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
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MP:0002295 | abnormal pulmonary circulation | "anomalous circulation of blood through the lungs" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Amhr2tm3(cre)Bhr/Amhr2+,Ctnnb1tm1Mmt/Ctnnb1+,Ptentm1Hwu/Ptentm1Hwu Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ
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MP:0002339 | abnormal lymph node morphology | "anomalous structure, size, or celluarity of the oval or bean shaped bodies located along the lymphatic system" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Ctnnb1tm2(Nfkbia)Rsu/Ctnnb1+,Tg(CMV-cre)1Cgn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6
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MP:0002351 | abnormal cervical lymph node morphology | "anomalous structure, development, or number of the lymph nodes found near the neck and shoulders" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0002404 | intestinal adenoma | "benign tumors of the small and large intestine" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Pou3f4-cre)32Cren/? Genetic Background: involves: 129X1/SvJ
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Fabp1-cre)1Mmt/? Genetic Background: involves: 129X1/SvJ
Allelic Composition: Bmi1tm1(cre/ERT)Mrc/Bmi1+,Ctnnb1tm1Mmt/Ctnnb1+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+ Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ
Allelic Composition: Ctnnb1tm1.2Wvv/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
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MP:0002451 | abnormal macrophage physiology | "abnormal function or response of the phagocytic leukocytes involved in innate immunity, early non-adaptive phases of host-defense, antigen presentation, and which act as effector cells in humoral and cell-mediated immunity" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2(Nfkbia)Rsu/Ctnnb1+,Tg(CMV-cre)1Cgn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6
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MP:0002544 | brachydactyly | "abnormally short digits" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Gt(ROSA)26Sortm1(Ctnnb1)Kem/Gt(ROSA)26Sortm1(Ctnnb1)Kem,Tg(Cdx1-cre)23Kem/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * FVB
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MP:0002579 | disorganized secondary lens fibers | "deformation or misalignment of the elongated cells that form the crystalline lens" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:70385] |
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Allelic Composition: Apctm3Mmt/Apc+ Genetic Background: involves: 129X1/SvJ * C57BL/6N
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MP:0002655 | abnormal keratinocyte morphology | "structural or developmental anomaly of the cells of the epidermis that produce keratin in the process of differentiating into the dead and fully keratinized cells of the stratum corneum" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(KRT5-rtTA)#Glk/0,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N
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MP:0002689 | abnormal molar morphology | "structural defect of the most posterior teeth located on either side of the jaw, and characterized by a large crown and broad chewing surface" [il:Ira Lu , Mouse Genome Informatics Curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Ctnnb1tm2(Nfkbia)Rsu/Ctnnb1+,Tg(CMV-cre)1Cgn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6
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MP:0002693 | abnormal pancreas physiology | "abberrant function of the organ that secretes pancreatic juice into the duodenum and secretes glucagon and insulin into the bloodstream" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Ctnnb1tm4Wbm/Ctnnb1tm4Wbm,Tg(Pdx1-cre)6Tuv/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
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MP:0002705 | dilated renal tubules | "enlarged lumens of the loops of Henle and/or collecting ducts of the kidney" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Wnt9btm1.1Amc/Wnt9btm1.2Amc,Tg(Cdh16-cre)91Igr/0 Genetic Background: involves: 129X1/SvJ * ICR
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MP:0002718 | abnormal inner cell mass | "malformed or absent cells of the blastocyst that develop into the body of the embryo" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Scn8amed-J/Scn8amed-J,Scnm1s/Scnm1s Genetic Background: involves: C57BL/6J
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MP:0002726 | abnormal pulmonary vein morphology | "structrual anomaly of the veins that return oxygenated blood from the lungs to the left atrium of the heart" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1tm1Mmt,Shhtm1(EGFP/cre)Cjt/Shh+ Genetic Background: involves: 129X1/SvJ
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MP:0002741 | small olfactory bulb | "reduced size of the forebrain region that coordinates neuronal signaling involved in the perception of smell; it receives input from the sensory neurons and outputs to the olfactory cortex" [J:79871] |
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Allelic Composition: Hoxb13tm2Mrc/Hoxb13tm2Mrc,Hoxd13tm1Mrc/Hoxd13tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0002768 | small adrenal glands | "reduced size of endocrine glands located above the kidneys responsible for hormone and epinephrine secretion" [J:78062] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Gt(ROSA)26Sortm1(Ctnnb1)Kem/Gt(ROSA)26Sortm1(Ctnnb1)Kem,Tg(Cdx1-cre)23Kem/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * FVB
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MP:0002792 | abnormal retinal vascularization | "malformation or disorganization of the blood vessels supplying the retina" [cml:Cathleen M. Lutz , Mouse Genome Informatics Curator] |
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Allelic Composition: Nrarptm1Vlcg/Nrarp+ Genetic Background: involves: C57BL/6J
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MP:0002797 | thigmotaxis | "preference of a mouse for the side walls of a cage or box; usually an indicator of increased anxiety response" [J:56814] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Pvalbtm1(cre)Arbr/Pvalb+ Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0002801 | abnormal long-term recognition memory | "defects in long-term memory for objects that is consolidated over hours and days after training." [CFG:Center for Functional Genomics , Northwestern University] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Pvalbtm1(cre)Arbr/Pvalb+ Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0002803 | abnormal operant conditional behavior | "defects in the operant conditioning system refers to abnormalities in scheduled controlled behavior; behavioral assessment occurs in an automated chamber where responses are reinforced with food" [CFG:Center for Functional Genomics , Northwestern University] |
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Allelic Composition: Hoxb13tm2Mrc/Hoxb13tm2Mrc,Hoxd13tm1Mrc/Hoxd13tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0002809 | enlarged spinal cord size | "larger appearance of the spinal cord" [J:83935] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Pou3f4-cre)32Cren/? Genetic Background: involves: 129X1/SvJ
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MP:0002831 | absent Peyer s patches | "lymphoid tissue missing from the mucosa of the small intestine" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0002896 | abnormal bone mineralization | "defect in the process by which minerals are deposited into bone" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ctnnb1tm1Max/Ctnnb1tm2Kem,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1
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MP:0002906 | susceptibility to pharmacologically induced seizures | "inability to withstand doses of pharmacological drugs that induce seizure activity in normal animals" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:69504] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Emx1tm1(cre)Yql/Emx1+ Genetic Background: B6.129-Emx1tm1(cre)Yql Ctnnb1tm2Kem
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MP:0002932 | abnormal joint | "defect in the articulation point of two or more bones" [RGD:Rat Genome Database submission, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Osr2tm2(cre)Jian/Osr2+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Twist2tm1(cre)Dor/Twist2+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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MP:0002947 | hemangioma | "proliferation of blood vessels leading to a mass that resembles a neoplasm" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:87544] |
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Allelic Composition: Gt(ROSA)26Sortm1(Vegfa*)Jhai/Gt(ROSA)26Sor+,Kdrtm1Wag/Kdrtm1Wag,Tg(Col2a1-cre)1Bhr/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * ICR * SJL
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MP:0002957 | intestinal adenocarcinoma | "malignant neoplasm of epithelial cells in the intestine" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+,Prom1tm1(cre/ERT2)Gilb/Prom1+ Genetic Background: involves: 129S6/SvEvTac * 129X1/SvJ
Allelic Composition: Ctnnb1tm1.2Wvv/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
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MP:0002989 | small kidney | "reduced physical bulk one or both of the organs responsible for urine secretion" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(Hoxb7-cre)5526Cmb/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Gt(ROSA)26Sortm1(Ctnnb1)Kem/Gt(ROSA)26Sortm1(Ctnnb1)Kem,Tg(Cdx1-cre)23Kem/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * FVB
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MP:0003055 | abnormal epiphyseal plate morphology | "malformed or absent cartilagenous center of ossification on the long bones permitting growth of the bone in both directions during development" [MeSH:National Library of Medicine - Medical Subject Headings, 2003] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 Genetic Background: involves: 129X1/SvJ * CD-1
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MP:0003087 | absent allantois | "missing fetal membrane which contributes to the formation of the umbilical cord and placenta" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Prrx1tm1Tex/Prrx1tm1Tex,Prrx2tm1Hubr/Prrx2tm1Hubr Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB
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MP:0003126 | abnormal vulva morphology | "anomaly in the structure of the external genitalia of the female" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Ctnnb1tm4Wbm/Ctnnb1tm4Wbm,Gli1tm3(cre/ERT2)Alj/Gli1+ Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac
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MP:0003129 | persistent cloaca | "the presence of a single external opening to which the urinary, digestive and reproductive tracts all connect" [smb:Susan M. Bello, Mouse Genome Informatics Curator, J:91491] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Gt(ROSA)26Sortm1(Ctnnb1)Kem/Gt(ROSA)26Sortm1(Ctnnb1)Kem,Tg(Cdx1-cre)23Kem/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * FVB
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MP:0003153 | early eyelid opening | "early average time for the first postnatal eye opening" [J:92240, smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0003190 | fused synovial joints | "partial or complete absence of separations containing synovial fluid between bones" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:93028] |
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Allelic Composition: Ctnnb1tm1Yy/Ctnnb1tm1Yy,Tg(Col2a1-cre)1Bhr/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6
Allelic Composition: Ctnnb1tm1Yy/Ctnnb1tm1Yy,Tg(Prnp-GFP/cre)1Blw/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6
Allelic Composition: Ctnnb1tm1Yy/Ctnnb1tm1Yy,Twist2tm1(cre)Dor/Twist2+ Genetic Background: involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6
Allelic Composition: Ctnnb1tm1Yy/Ctnnb1tm1.1Yy,Ptch1tm1Yy/Ptch1tm1.1Yy,Tg(Col2a1-cre)1Bhr/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
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MP:0003205 | testicular atrophy | "wasting of the male reproductive glands resulting in reduced size" [RGD:Rat Genome Database submission] |
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Allelic Composition: Amhr2tm3(cre)Bhr/Amhr2+,Ctnnb1tm1Mmt/Ctnnb1+ Genetic Background: involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
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MP:0003229 | abnormal vitelline vasculature | "malformation in the vessels of the yolk sac" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:93257] |
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Allelic Composition: Sox9tm1Gsr/Sox9+,Tg(Col2a1-cre)1Bhr/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * SJL
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MP:0003232 | abnormal forebrain development | "anomaly in the formation or patterning of the anterior primitive cerebral vesicle; most rostral of three primary vesicles of the embryonic neural tube" [J:93081, smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Ctnnb1tm1Kba/Ctnnb1tm1Kba Genetic Background: involves: 129S6/SvEvTac * C57BL/6
Allelic Composition: Ctnnb1tm1Max/Ctnnb1+,Hesx1tm1(cre)Jpmb/Hesx1tm1Icar Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * 129S1/Sv * 129X1/SvJ
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1+,Hesx1tm1(cre)Jpmb/Hesx1tm1Icar Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * 129S1/Sv * 129X1/SvJ
Allelic Composition: Ctnnb1tm1Max/Ctnnb1+,Hesx1tm1Icar/Hesx1tm1Icar Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ
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MP:0003236 | abnormal lens capsule morphology | "malformation in the elastic, clear, membrane-like structure, that is outer most layer of the lens" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:93301] |
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Allelic Composition: Apctm3Mmt/Apc+ Genetic Background: involves: 129X1/SvJ * C57BL/6N
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MP:0003237 | abnormal lens epithelium morphology | "malformation in the one or more of the layers of epithelial cells in the lens" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:93301] |
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Allelic Composition: Apctm3Mmt/Apc+ Genetic Background: involves: 129X1/SvJ * C57BL/6N
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1tm1Mmt,Tg(Cryaa-cre)10Mlr/0 Genetic Background: involves: 129X1/SvJ * FVB/N
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MP:0003321 | tracheoesophageal fistula | "an abnormal passage between the esophagus and the trachea, acquired or congenital, often associated with esophageal atresia" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1tm1Mmt,Shhtm1(EGFP/cre)Cjt/Shh+ Genetic Background: involves: 129X1/SvJ
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MP:0003331 | hepatocellular carcinoma | "malignant neoplasm arising from liver cells" [ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Apctm1Tno/Apc+ Genetic Background: involves: 129/Sv * 129S4/SvJae * C57BL/6
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MP:0003334 | pancreatic fibrosis | "invasion of fibrous connective tissue into the pancreas, often resulting from inflammation or injury " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Ctnnb1tm4Wbm/Ctnnb1tm4Wbm,Tg(Pdx1-cre)6Tuv/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
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MP:0003357 | impaired granulosa cell differentiation | "atypical differentiation of the layer of small cells that forms the wall of an ovarian follicle" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:43075] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Krastm4Tyj/Kras+,Tg(CYP19A1-cre)1Jri/0 Genetic Background: involves: 129S4/SvJae * 129X1/SvJ * C57BL/6
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Ptentm1Hwu/Ptentm1Hwu,Tg(CYP19A1-cre)1Jri/0 Genetic Background: involves: 129S4/SvJae * 129X1/SvJ * C57BL/6
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MP:0003413 | hair follicle degeneration | "a retrogressive impairment of function or destruction of the hair follicle" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator, J:94517] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(KRT5-rtTA)#Glk/0,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N
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MP:0003417 | premature endochondral bone ossification | "early onset of bone formation in bones that form from cartilage" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:94631] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 Genetic Background: involves: 129X1/SvJ * CD-1
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MP:0003419 | delayed endochondral bone ossification | "late onset of bone formation in bones that form from cartilage" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:94631] |
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Allelic Composition: Ctnnb1tm1Yy/Ctnnb1tm1.1Yy,Ptch1tm1Yy/Ptch1tm1.1Yy,Tg(Col2a1-cre)1Bhr/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
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MP:0003420 | delayed intramembranous bone ossification | "late onset of bone formation in bones that form without a cartilagenous intermediate including the cranium and clavicle" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:94631] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 Genetic Background: involves: 129X1/SvJ * CD-1
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MP:0003424 | premature neuronal precursor differentiation | "earlier than normal transformation of neuronal precursor cells into neurons" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:94391] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,H2afvTg(Wnt1-cre)11Rth/0 Genetic Background: involves: 129 * C57BL/6 * CBA/J
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MP:0003446 | renal hypoplasia | "decreased cell number in the kidney leading to reduced size" [llw2:Linda Washburn , Mouse Genome Informatics Curator] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1tm1Mmt,Tcf21tm1(cre)Seq/Tcf21+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tcf21tm1(cre)Seq/Tcf21+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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MP:0003449 | abnormal intestinal goblet cells | "malformation of the unicellular mucin-secreting glands" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:95282] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2(Nfkbia)Rsu/Ctnnb1+,Tg(CMV-cre)1Cgn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6
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MP:0003456 | absent tail | "completely lacking the appendage at the caudal end of the vertebral column " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Gt(ROSA)26Sortm1(Ctnnb1)Kem/Gt(ROSA)26Sortm1(Ctnnb1)Kem,Tg(Cdx1-cre)23Kem/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * FVB
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MP:0003553 | abnormal foreskin morphology | "anomaly of the loose fold of skin that covers the penis" [ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Ctnnb1tm4Wbm/Ctnnb1tm4Wbm,Gli1tm3(cre/ERT2)Alj/Gli1+ Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac
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MP:0003604 | single kidney | |
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Allelic Composition: Agrnnmf380/Agrnnmf380 Genetic Background: involves: C57BL/6J * CAST
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MP:0003605 | fused kidneys | |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tcf21tm1(cre)Seq/Tcf21+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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MP:0003632 | abnormal nervous system morphology | |
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Allelic Composition: Hoxb4tm1Nrm/Hoxb4tm1Nrm Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Pou3f4-cre)32Cren/? Genetic Background: involves: 129X1/SvJ
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MP:0003675 | kidney cysts | "abnormal membranous sacs in any portion of the pair of organs responsible for urine secretion" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Wnt9btm1.1Amc/Wnt9btm1.2Amc,Tg(Cdh16-cre)91Igr/0 Genetic Background: involves: 129X1/SvJ * ICR
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Cdh16-cre)91Igr/0 Genetic Background: involves: 129X1/SvJ * ICR
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1tm1Mmt,Tcf21tm1(cre)Seq/Tcf21+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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MP:0003704 | abnormal hair follicle development | "anomalous development of the epidermis from which the hair shaft develops " [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2(Nfkbia)Rsu/Ctnnb1+,Tg(CMV-cre)1Cgn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6
Allelic Composition: Ctnnb1tm1Yy/Ctnnb1tm1Yy,Tg(Prrx1-cre)1Cjt/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * SJL/J
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MP:0003723 | abnormal long bone morphology | "malformation of any of the several elongated bones of the extremities
" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: Cftrtm1Unc/Cftrtm1Unc Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
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MP:0003743 | abnormal facial morphology | "anomalous structure or development of the face" [ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Axin1tm4Cos/Axin1tm4Cos,Ctnnb1tm2.1Kem/Ctnnb1+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Tcfap2a-cre)1Will/0 Genetic Background: involves: 129X1/SvJ * C57BL/6
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(Tcfap2a-cre)1Will/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0003795 | abnormal bone structure | |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Twist2tm1(cre)Dor/Twist2+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tcf7tm1Cle/Tcf7+ Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ
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MP:0003809 | abnormal hair shaft morphology | "irregular or unusual structure of the cuticle, and/or cortex and/or medulla of a hair" [llw2:Linda Washburn , Mouse Genome Informatics Curator] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Corintm2(cre)Bamo/Corin+,Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
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MP:0003826 | abnormal Mullerian duct morphology | "malformation of the transient embryonic tubes that empty into the cloaca and in the female develop into the oviducts, uterus, and vagina" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Wnt4tm1.2Bhr/Wnt4tm1.2Bhr Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6J
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MP:0003869 | ectopic cartilage | "positional abnormality of cartilage" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Tcfap2a-cre)1Will/0 Genetic Background: involves: 129X1/SvJ * C57BL/6
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Twist2tm1(cre)Dor/Twist2+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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MP:0003886 | abnormal embryonic epiblast morphology | "anomaly in the development/organization of the tissue that gives rise to the ectoderm, endoderm and mesoderm of the embryo proper" [brs:Beverly Richards-Smith, Mouse Genome Informatics Curator] |
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Allelic Composition: Prrx1tm1Tex/Prrx1tm1Tex,Prrx2tm1Hubr/Prrx2tm1Hubr Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB
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MP:0003887 | increased hepatocyte apoptosis | "increase in the number of hepatocytes undergoing programmed cell death" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2(Nfkbia)Rsu/Ctnnb1+,Tg(CMV-cre)1Cgn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6
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MP:0003888 | liver hemorrhage | "bleeding within the liver" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2(Nfkbia)Rsu/Ctnnb1+,Tg(CMV-cre)1Cgn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6
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MP:0003895 | increased ectoderm apoptosis | "increase in the number of ectoderm cells undergoing programmed cell death during development" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator] |
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Allelic Composition: Apoetm1Bres/Apoetm1Bres,Cx3cr1tm1Ifc/Cx3cr1tm1Ifc Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
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MP:0003935 | abnormal craniofacial development | "anomaly in the process of forming the face and/or cranium" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ctnnb1tm1Kba/Ctnnb1tm1Kba Genetic Background: involves: 129S6/SvEvTac * C57BL/6
Allelic Composition: Ctnnb1tm1.2Wvv/Ctnnb1tm1.2Wvv Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
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MP:0003936 | abnormal reproductive system development | "developmental anomaly of any of the organs involved in the reproductive system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Gt(ROSA)26Sortm1(Fgf8)Lma/Gt(ROSA)26Sor+,Tg(Msx2-cre)5Rem/0 Genetic Background: involves: C57BL/6 * CBA
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MP:0003957 | abnormal nitric oxide homeostasis | "anomaly in the state of equilibrium in the body of nitric oxide, a free radical gas and a potent vasodilator" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0003974 | abnormal endocardium morphology | "malformation of the thin serous membrane, primarily composed of endothelial tissue, that lines the interior of the heart" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Sox9tm1Gsr/Sox9+,Tg(Col2a1-cre)1Bhr/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * SJL
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MP:0003984 | embryonic growth retardation | "slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ctnnb1tm2.1Kem/Ctnnb1+,Sall4Gt(W097E01)Flo/Sall4+ Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6
Allelic Composition: Ctnnb1tm1Kba/Ctnnb1tm1Kba Genetic Background: involves: 129S6/SvEvTac * C57BL/6
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MP:0004007 | abnormal lung vasculature | "malformation or disorganization of the blood vessels of the lung" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1tm1Mmt,Shhtm1(EGFP/cre)Cjt/Shh+ Genetic Background: involves: 129X1/SvJ
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MP:0004016 | decreased bone mass | "a reduction in the total amount of bone tissue contained in the skeleton" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tcf7tm1Cle/Tcf7+ Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ
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MP:0004073 | caudal body truncation | "caudal part of body truncated with anterior portion relatively normal" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ctnnb1Bfc/Ctnnb1+,Lrp6Gw/Lrp6+ Genetic Background: either: (involves: 101/H * BALB/cCrl * C3H) or (involves: 101/H * BALB/cCrl * C3H * C57BL/6)
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Gt(ROSA)26Sortm1(Ctnnb1)Kem/Gt(ROSA)26Sor+,Tg(Cdx1-cre)23Kem/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * FVB
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Tg(T-cre)1Lwd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H * C57BL/6
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Tg(T-cre/ERT2)1Lwd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H/HeNcr * C57BL/6NCr
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MP:0004081 | abnormal globus pallidus morphology | "malformation of one of the basal ganglia involved with control of voluntary movement in the brain; consists of an external and an internal segment" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3] |
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Allelic Composition: Hoxb13tm2Mrc/Hoxb13tm2Mrc,Hoxd13tm1Mrc/Hoxd13tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0004100 | abnormal spinal cord interneuron morphology | "malformation or absence of neurons that exclusively interact with other neurons in the spinal cord" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Juptm1Ruiz/Juptm1Ruiz,Olig2tm1(cre)Tmj/Olig2+ Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ
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MP:0004163 | abnormal adenophysis morphology | "any malformation or absence of the anterior part of the pituitary that secretes a variety of hormones; its function is regulated by the hypothalamus" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ss18tm1Adg/Ss18tm1Adg Genetic Background: B6.Cg-Ss18tm1Adg
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Sox2tm1.1(cre/ERT2)Jpmb/Sox2+ Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
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MP:0004205 | absent hyoid bone | "absence of the U-shaped bone lying between the mandible and the larynx that supports the tongue muscles" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(Tcfap2a-cre)1Will/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0004207 | squamous cell carcinoma | "a carcinoma that arises from stratified squamous epithelium that occurs in sites where glandular or columnar epithelium is normally present, such as the skin, esophagus, lungs and cervix" [MGI:rbabiuk "Randall Babiuk, Mouse Genome Informatics Curator"] |
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Allelic Composition: Bmpr1atm2.1Bhr/Bmpr1atm2.1Bhr,Ctnnb1tm1Mmt/Ctnnb1+,Krt14tm1.1(cre)Wbm/Krt14+ Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * 129X1/SvJ
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MP:0004320 | split sternum | "the appearance of an abnormal division in the long flat bone of the chest which articulates with clavicle and first seven rib pairs" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Twist2tm1(cre)Dor/Twist2+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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MP:0004354 | absent deltoid tuberosity | "missing the rough elevation at the middle of the lateral side of the shaft of the humerus to which the deltoid muscle attaches" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Apoetm1Bres/Apoetm1Bres,Cx3cr1tm1Ifc/Cx3cr1tm1Ifc Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(Msx2-cre)5Rem/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
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MP:0004359 | short ulna | "reduced length of the medial and larger of the two bones of the forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(Msx2-cre)5Rem/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
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MP:0004486 | decreased response of heart to induced stress | "decrease in severity of the physiological response of the heart to induced stress such as cardiac hypertrophy due to mechanical pressure overload from aortic banding" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Pcdh15av-6J/Pcdh15av-6J Genetic Background: B6(129P2)-Pcdh15av-6J
Allelic Composition: Ctnnb1tm2(Nfkbia)Rsu/Ctnnb1+,Tg(Myh6-cre)2182Mds/0 Genetic Background: B6.Cg-Ctnnb1tm2(Nfkbia)Rsu Tg(Myh6-cre)2182Mds
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MP:0004538 | abnormal maxillary shelf | "any structural anomaly of the outgrowth of the maxilla that normally fuses with palatine shelf to form secondary (hard) palate" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(Tcfap2a-cre)1Will/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0004539 | absent maxilla | "missing the upper bony framework of the mouth where the superior teeth are held" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+,H2afvTg(Wnt1-cre)11Rth/0 Genetic Background: involves: 129 * C57BL/6 * CBA/J
Allelic Composition: Ctnnb1tm1.2Wvv/Ctnnb1tm1.2Wvv Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
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MP:0004572 | fusion of basioccipital and basisphenoid bone | "union of the basioccipital and basisphenoid bones into one structure, when this fusion does not normally occur (such as in a species where these bones normally persist as separate entities)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(Tcfap2a-cre)1Will/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0004609 | vertebral fusion | "the union of one or more vertebrae into a single structure" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Gt(ROSA)26Sortm1(Ctnnb1)Kem/Gt(ROSA)26Sortm1(Ctnnb1)Kem,Tg(Cdx1-cre)23Kem/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * FVB
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MP:0004610 | small vertebrae | "reduced size of the bony segments of the spinal column" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Gt(ROSA)26Sortm1(Ctnnb1)Kem/Gt(ROSA)26Sortm1(Ctnnb1)Kem,Tg(Cdx1-cre)23Kem/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * FVB
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MP:0004672 | short ribs | "reduced length of the bones forming the bony wall of the chest" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Gt(ROSA)26Sortm1(Ctnnb1)Kem/Gt(ROSA)26Sortm1(Ctnnb1)Kem,Tg(Cdx1-cre)23Kem/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * FVB
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MP:0004686 | decreased length of long bones | "reduced end-to-end length of the several elongated bones of the extremities" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Psen1tm1Jzt/Psen1tm1Jzt Genetic Background: involves: C57BL/6 * CBA
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(Col2a1-cre)1Bhr/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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MP:0004726 | abnormal nasal capsule morphology | "any structural abnormality in the cartilage around the developing nasal cavity of the embryo" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm1.2Wvv/Ctnnb1tm1.2Wvv Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
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MP:0004791 | absent lower incisors | "missing the lower pair of long pointed teeth that are the most anterior and prominent in the jaw" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tcf7tm1Cle/Tcf7+ Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ
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MP:0004793 | abnormal synaptic vesicle clustering | "any functional anomaly in the process of accumulation of synaptic vesicles at the active zone of presynaptic membranes" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hoxb13tm2Mrc/Hoxb13tm2Mrc,Hoxd13tm1Mrc/Hoxd13tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0004811 | abnormal neuron physiology | "anomalous function of the cells of the nervous system that receive, conduct, and transmit impulses" [MESH:National Library of Medicine_Medical Subject Headings] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Pvalbtm1(cre)Arbr/Pvalb+ Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0004830 | short incisors | "reduced length of the long pointed teeth; most anterior and prominent in the jaw" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0004936 | abnormal ureteric bud branching morphogenesis | "partial or complete failure of the ureteric bud to repeatedly divide into lobules during development of the kidney" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(Hoxb7-cre)5526Cmb/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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MP:0004984 | increased osteoclast cell number | "greater than average number of the bone resorpting cells that remove bone tissue by degrading the mineralized matrix" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tcf7tm1Cle/Tcf7+ Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Ctsktm1(cre)Ska/Ctsk+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrlj * CBA/JNCrlj
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1+,Ctsktm1(cre)Ska/Ctsk+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrlj * CBA/JNCrlj
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Lyz2tm1(cre)Ifo/Lyz2+ Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1+,Lyz2tm1(cre)Ifo/Lyz2+ Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1+,Tg(Tek-cre)1Ywa/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1+,Ppargtm1.1(tTA)Jmgr/Pparg+,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0004985 | decreased osteoclast cell number | "reduced number of the bone resorpting cells that remove bone tissue by degrading the mineralized matrix" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tcf7tm1Cle/Tcf7+ Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(Tek-cre)1Ywa/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Ppargtm1.1(tTA)Jmgr/Pparg+,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Ppargtm1.1(tTA)Jmgr/Pparg+,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
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MP:0004992 | increased bone resorption | "greater than average amount of degradation of the organic and inorganic phases of bone by absorption, usually by the abnormal function or number of osteoclasts" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Ctsktm1(cre)Ska/Ctsk+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrlj * CBA/JNCrlj
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1+,Ctsktm1(cre)Ska/Ctsk+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrlj * CBA/JNCrlj
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Lyz2tm1(cre)Ifo/Lyz2+ Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1+,Lyz2tm1(cre)Ifo/Lyz2+ Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1+,Tg(Tek-cre)1Ywa/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1+,Ppargtm1.1(tTA)Jmgr/Pparg+,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0004993 | decreased bone resorption | "reduced amount of degradation of the organic and inorganic phases of bone by absorption, usually by the abnormal function or number of osteoclasts" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(Tek-cre)1Ywa/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Ppargtm1.1(tTA)Jmgr/Pparg+,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Ctsktm1(cre)Ska/Ctsk+ Genetic Background: involves: 129X1/SvJ * C57BL/6NCrlj * CBA/JNCrlj
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Lyz2tm1(cre)Ifo/Lyz2+ Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Ppargtm1.1(tTA)Jmgr/Pparg+,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
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MP:0005027 | increased susceptibility to parasitic infection | "greater likelihood that an organism will develop ill effects from a parasitic infection or from components of or toxins produced by parasites " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0005077 | abnormal melanogenesis | "failure of or anomaly in the biosynthetic pathway of melanin formation in cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:5346] |
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Allelic Composition: Wlstm1Xzg/Wlstm1Xzg,Tg(Prrx1-cre)1Cjt/0 Genetic Background: involves: C57BL/6J * SJL/J
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MP:0005108 | abnormal ulna morphology | "malformation of the medial and larger of the two bones of the forearm" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:83132] |
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Allelic Composition: Apoetm1Bres/Apoetm1Bres,Cx3cr1tm1Ifc/Cx3cr1tm1Ifc Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Gt(ROSA)26Sortm1(Fgf8)Lma/Gt(ROSA)26Sor+,Tg(Msx2-cre)5Rem/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
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MP:0005161 | hematuria | "presence of blood in the urine" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:78193] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1tm1Mmt,Tg(Upk2-cre)6Xrw/0,Tg(Upk2-HRAS*Q61L)5Xrw/0 Genetic Background: involves: 129X1/SvJ * FVB/N
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MP:0005167 | abnormal blood-brain barrier | "anomaly in the structure or function of the group of barriers and transport systems in the brain capillary endothelium that controls the entrance of substances into the brain extracellular space from the blood" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Edil3Tg(Sox2-cre)1Amc/Edil3+,Wnt7atm1Amc/Wnt7atm1Amc,Wnt7btm1Parr/Wnt7btm2Amc Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
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MP:0005181 | decreased circulating estradiol level | "less than the normal blood concentration of this most potent naturally occurring estrogen in mammals" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Krastm4Tyj/Kras+,Tg(CYP19A1-cre)1Jri/0 Genetic Background: involves: 129S4/SvJae * 129X1/SvJ * C57BL/6
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Ptentm1Hwu/Ptentm1Hwu,Tg(CYP19A1-cre)1Jri/0 Genetic Background: involves: 129S4/SvJae * 129X1/SvJ * C57BL/6
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MP:0005185 | decreased circulating progesterone level | "less than the normal blood concentration of this antiestrogenic steroid" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:66817] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Krastm4Tyj/Kras+,Tg(CYP19A1-cre)1Jri/0 Genetic Background: involves: 129S4/SvJae * 129X1/SvJ * C57BL/6
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Ptentm1Hwu/Ptentm1Hwu,Tg(CYP19A1-cre)1Jri/0 Genetic Background: involves: 129S4/SvJae * 129X1/SvJ * C57BL/6
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MP:0005202 | lethargy | "mild impairment of consciousness resulting in reduced alertness and awareness; ultimately due to generalized brain dysfunction" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2(Nfkbia)Rsu/Ctnnb1+,Tg(CMV-cre)1Cgn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6
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MP:0005220 | abnormal exocrine pancreas morphology | "malformation of the acinar gland portion of the pancreas that secretes digestive enzymes " [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Ctnnb1tm4Wbm/Ctnnb1tm4Wbm,Tg(Pdx1-cre)6Tuv/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
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MP:0005221 | abnormal rostral-caudal axis patterning | "anomaly in the development or formation of the axis that runs from the head to the tail of the body" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Ctnnb1tm1Wbm/Ctnnb1tm1Wbm Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2Wbm/Ctnnb1tm2Wbm Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm3Wbm/Ctnnb1tm3Wbm Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2.1Kem/Ctnnb1+,Otx2tm1(Dkk1)Imat/Otx2tm1(Dkk1)Imat Genetic Background: involves: 129/Sv * C57BL/6 * CBA
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MP:0005238 | increased brain size | "larger than the normal physical proportions of the brain" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:57958] |
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Allelic Composition: Hoxb13tm2Mrc/Hoxb13tm2Mrc,Hoxd13tm1Mrc/Hoxd13tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Pou3f4-cre)32Cren/? Genetic Background: involves: 129X1/SvJ
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MP:0005287 | narrow eye opening | "less than the normal distance from one eyelid to the other " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:71350] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0005296 | abnormal humerus morphology | "malformation of the bone of the forelimb that articulates with the scapula above and the radius and ulna below" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Apoetm1Bres/Apoetm1Bres,Cx3cr1tm1Ifc/Cx3cr1tm1Ifc Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
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MP:0005300 | abnormal corneal stroma morphology | "structural anomaly of the lamellated connective tissue of the cornea" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0005315 | absent pituitary gland | "missing gland that is normally suspended from the base of the hypothalamus and which secretes somatotropins, prolactin, TSH (thyroid-stimulating hormone), gonadotropins, adrenal corticotropin" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:30559] |
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Allelic Composition: Ss18tm1Adg/Ss18tm1Adg Genetic Background: B6.Cg-Ss18tm1Adg
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MP:0005358 | abnormal incisor morphology | "structural defect of the long pointed teeth; most anterior and prominent in the jaw" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:85574] |
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Allelic Composition: Ctnnb1tm2(Nfkbia)Rsu/Ctnnb1+,Tg(CMV-cre)1Cgn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6
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MP:0005359 | growth retardation of incisors | "developmental delay of the growth of the incisors, the long pointed teeth, most anterior and prominent in the jaw " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:85574] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1+,Osr2tm2(cre)Jian/Osr2+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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MP:0005503 | abnormal tendon morphology | "structural anomaly of the fibrous bands or cords of connective tissue at the ends of muscle fibers that attach muscles to bones and other structures" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, J:45509] |
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Allelic Composition: Wlstm1Xzg/Wlstm1Xzg,Tg(Prrx1-cre)1Cjt/0 Genetic Background: involves: C57BL/6J * SJL/J
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MP:0005504 | abnormal ligament morphology | "structural anomaly of the flexible bands of fibrous tissue that connect the articular extremities of bones " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, J:45509] |
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Allelic Composition: Wlstm1Xzg/Wlstm1Xzg,Tg(Prrx1-cre)1Cjt/0 Genetic Background: involves: C57BL/6J * SJL/J
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MP:0005508 | abnormal skeleton morphology | "malformation of the bony framework of the body in vertebrates" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Amer1tm1.1Nbar/Y,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 Genetic Background: involves: 129S4/SvJae * C57BL/6 * CD-1 * SJL
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Twist2tm1(cre)Dor/Twist2+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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MP:0005545 | abnormal lens development | "aberrant formation of the transparent structure of the eye responsible for focusing light rays" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Tcfap2a-cre)1Will/0 Genetic Background: involves: 129X1/SvJ * C57BL/6
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MP:0005579 | absent outer ear | "missing auricles or external acoustic meatus" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:17694] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Tcfap2a-cre)1Will/0 Genetic Background: involves: 129X1/SvJ * C57BL/6
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MP:0005587 | abnormal Meckel s cartilage morphology | "structural anomaly of this cartilage bar in the mandibular arch that forms a temporary supporting structure in the embryonic mandible; gives rise to middle ear bones and sphenomandibular and anterior malleolar ligaments" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:17694] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Tcfap2a-cre)1Will/0 Genetic Background: involves: 129X1/SvJ * C57BL/6
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MP:0005605 | increased bone mass | "an increase in the total amount of bone tissue contained in the skeleton" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tcf7tm1Cle/Tcf7+ Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ
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MP:0006000 | abnormal corneal epithelium | "malformation in the one or more of the layers of epithelial cells covering the front of the cornea" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0006009 | abnormal neuronal migration | "defective or impaired movement of immature neurons from germinal zones to specific positions where they will reside as they mature" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Juptm1Ruiz/Juptm1Ruiz,Olig2tm1(cre)Tmj/Olig2+ Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ
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MP:0006054 | spinal hemorrhage | "bleeding into the spine" [RGD:Rat Genome Database submission, smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Edil3Tg(Sox2-cre)1Amc/Edil3+,Wnt7atm1Amc/Wnt7atm1Amc,Wnt7btm1Parr/Wnt7btm2Amc Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
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MP:0006055 | abnormal vascular endothelial cell morphology | "malformation in the cells that line the vasculature" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Sox9tm1Gsr/Sox9+,Tg(Col2a1-cre)1Bhr/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * SJL
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MP:0006236 | absent meibomian glands | "missing meibomian glands" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2(Nfkbia)Rsu/Ctnnb1+,Tg(CMV-cre)1Cgn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6
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MP:0006262 | testis tumor | "presence of abnormal rapidly proliferating cells in the testis, usually in the form of a distinct mass" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:60034] |
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Allelic Composition: Amhr2tm3(cre)Bhr/Amhr2+,Ctnnb1tm1Mmt/Ctnnb1+,Ptentm1Hwu/Ptentm1Hwu Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ
Allelic Composition: Amhr2tm3(cre)Bhr/Amhr2+,Ctnnb1tm1Mmt/Ctnnb1+ Genetic Background: involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Krastm4Tyj/Kras+,Amhr2tm3(cre)Bhr/Amhr2+ Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
Allelic Composition: Amhr2tm3(cre)Bhr/Amhr2+,Ctnnb1tm1Mmt/Ctnnb1+,Ptentm1Hwu/Ptentm1Hwu Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
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MP:0006270 | abnormal mammary gland growth during lactation | "anomaly in the final stage of mammary growth that occurs during the start of lactation" [llw2:Linda Washburn , Mouse Genome Informatics Curator] |
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Allelic Composition: Slc1a2tm1.1Ncd/Slc1a2tm1.1Ncd,Tg(Pdx1-cre)1Heed/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
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MP:0006279 | abnormal limb development | "anomaly in the formation of the limbs" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm1Max/Ctnnb1tm2Kem,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1
Allelic Composition: Ctnnb1tm4Wbm/Ctnnb1tm4Wbm,Tg(Prrx1-cre)98Mlgn/0 Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Ctnnb1tm1Yy/Ctnnb1tm1Yy,Tg(Prrx1-cre)1Cjt/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * SJL/J
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MP:0006281 | abnormal tail development | "anomaly in the formation of the tail" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Gt(ROSA)26Sortm1(Fgf8)Lma/Gt(ROSA)26Sor+,Tg(Msx2-cre)5Rem/0 Genetic Background: involves: C57BL/6 * CBA
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MP:0006283 | medulloblastoma | "a solid, cancerous tumor originating in the cerebellum of the brain and of primitive neuroectodermal origin " [MGI:rbabiuk "Randall Babiuk, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Pik3catm1Gilb/Pik3ca+,Trp53tm1Brn/Trp53+,Tg(Fabp7-cre,-lacZ)3Gtm/0 Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * CBA
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Trp53tm1Brn/Trp53+,Tg(Fabp7-cre,-lacZ)3Gtm/0 Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * CBA
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MP:0006292 | abnormal olfactory placode morphology | "any structural abnormality in the paired ectodermal placodes that come to lie in the bottom of the olfactory pits as the pits are deepened by the growth of the surrounding medial and lateral nasal processes" [J:62024, MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(Tcfap2a-cre)1Will/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0006305 | abnormal optic eminence morphology | "malformation of the embryonic structure that gives rise to the corneal ectoderm" [J:119812, MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator", UNSW_embryology site:http://embryology.med.unsw.edu.au/Notes/eye.htm#stage13] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(Tcfap2a-cre)1Will/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0006322 | abnormal perichondrium morphology | "any structural anomaly of the fibrous connective tissue that surrounds all non-joint end cartilage" [ISBN:0-8036-0655-99 "Taber s Cyclopedic Medical Dictionary, 19th edition", J:117033, MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm1Yy/Ctnnb1tm1.1Yy,Ptch1tm1Yy/Ptch1tm1.1Yy,Tg(Col2a1-cre)1Bhr/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
Allelic Composition: Ctnnb1tm1Yy/Ctnnb1tm1.1Yy,Tg(Col2a1-cre)1Bhr/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
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MP:0006346 | small branchial arch | "reduced size of one or more of the branchial arches" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm1Kba/Ctnnb1tm1Kba Genetic Background: involves: 129S6/SvEvTac * C57BL/6
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+,H2afvTg(Wnt1-cre)11Rth/0 Genetic Background: involves: 129 * C57BL/6 * CBA/J
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MP:0006402 | small molars | "reduced size of the most posterior teeth located on either side of the jaw, and characterized by a large crown and broad chewing surface" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0008000 | ovary tumor | "presence of abnormal rapidly proliferating cells in the ovary, usually in the form of a distinct mass" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Amhr2tm3(cre)Bhr/Amhr2+,Ctnnb1tm1Mmt/Ctnnb1+,Ptentm1Hwu/Ptentm1Hwu Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(CYP19A1-cre)1Jri/0 Genetic Background: involves: 129X1/SvJ * C57BL/6
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Krastm4Tyj/Kras+,Tg(CYP19A1-cre)1Jri/0 Genetic Background: involves: 129S4/SvJae * 129X1/SvJ * C57BL/6
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Ptentm1Hwu/Ptentm1Hwu,Tg(CYP19A1-cre)1Jri/0 Genetic Background: involves: 129S4/SvJae * 129X1/SvJ * C57BL/6
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MP:0008011 | intestinal polyps | "abnormal tissue masses that protrude into the lumen of the intestine and are tethered to the wall of the intestine" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: ApcMin/Apctm1Tno,Ctnnb1tm4.1Wbm/Ctnnb1+ Genetic Background: involves: 129/Sv * 129P2/OlaHsd * 129S4/SvJae * C57BL/6
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Lgr5tm1(cre/ERT2)Cle/Lgr5+ Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ
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MP:0008014 | lung tumor | "presence of abnormal, rapidly proliferating cells on the lung usually in the form of a distinct mass" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Fgfr3tm4Cxd/Fgfr3+,Tg(Upk2-cre)6Xrw/0 Genetic Background: involves: 129S6/SvEvTac * 129X1/SvJ * FVB/N
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Krastm4Tyj/Kras+,Tg(Upk2-cre)6Xrw/0 Genetic Background: involves: 129S4/SvJae * 129X1/SvJ * FVB/N
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MP:0008133 | decreased Peyer s patch number | "reduction in the number of the protruding lymphoid tissue located on the mucosa of the small intestine that is composed of densly packed B cell follicles" [PMID:15841100] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0008135 | small Peyer s patches | "reduced size of the protruding lymphoid tissue located on the mucosa of the small intestine that is composed of densly packed B cell follicles" [PMID:15841100] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0008143 | abnormal dendrite morphology | "any structural anomaly of the highly branched tree-like process of a neuron that serves as a receptive field and conducts impulses toward the cell body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", MGI:rbabiuk "Randall Babiuk, Mouse Genome Informatics Curator"] |
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Allelic Composition: Thtm1.1Ich/Thtm1.1Ich Genetic Background: Not Specified
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MP:0008154 | decreased diameter of humerus | "reduced width of the cross-sectional distance that extends from one lateral edge of the humerus, through its center and to the opposite lateral edge" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(Msx2-cre)5Rem/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
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MP:0008223 | absent hippocampal commissure | "absence of the triangular subcallosal plate of commissural fibers resulting from the converging of the right and left fornix bundles which exchange numerous fibers and which curve back in the contralateral fornix to end in the hippocampus of the opposite side" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Emx1tm1(cre)Yql/Emx1+ Genetic Background: B6.129-Emx1tm1(cre)Yql Ctnnb1tm2Kem
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MP:0008264 | absent hippocampus CA1 region | |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Emx1tm1(cre)Yql/Emx1+ Genetic Background: B6.129-Emx1tm1(cre)Yql Ctnnb1tm2Kem
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MP:0008266 | absent hippocampus CA2 region | |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Emx1tm1(cre)Yql/Emx1+ Genetic Background: B6.129-Emx1tm1(cre)Yql Ctnnb1tm2Kem
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MP:0008268 | absent hippocampus CA3 region | |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Emx1tm1(cre)Yql/Emx1+ Genetic Background: B6.129-Emx1tm1(cre)Yql Ctnnb1tm2Kem
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MP:0008271 | abnormal bone ossification | "any anomaly in the formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance" [GO:0001503] |
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Allelic Composition: Ctnnb1tm1Max/Ctnnb1tm2Kem,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 Genetic Background: involves: 129X1/SvJ * CD-1
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MP:0008274 | failure of bone ossification | "failure to initiate or a block in the process of the formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance" [GO:0001503] |
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Allelic Composition: Ctnnb1tm1Yy/Ctnnb1tm1.1Yy,Tg(Col2a1-cre)1Bhr/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Twist2tm1(cre)Dor/Twist2+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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MP:0008321 | small adenohypophysis | "reduced size of the anterior part of the pituitary that secretes a variety of hormones" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ss18tm1Adg/Ss18tm1Adg Genetic Background: B6.Cg-Ss18tm1Adg
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MP:0008330 | absent somatotrophs | "absence of an acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin" [CL:0000295, MESH:A06.407.747.608.937] |
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Allelic Composition: Ss18tm1Adg/Ss18tm1Adg Genetic Background: B6.Cg-Ss18tm1Adg
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MP:0008333 | absent lactotrophs | "absence of an acidophilic cell of the anterior pituitary that produces prolactin" [CL:0000439, MESH:A06.407.747.608.812] |
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Allelic Composition: Ss18tm1Adg/Ss18tm1Adg Genetic Background: B6.Cg-Ss18tm1Adg
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MP:0008335 | decreased gonadotroph cell number | "reduced number of the anterior pituitary cells that can produce both follicle stimulating hormone (FSH) and luteinizing hormone (LH)" [MESH:A06.407.747.608.750] |
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Allelic Composition: Ss18tm1Adg/Ss18tm1Adg Genetic Background: B6.Cg-Ss18tm1Adg
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MP:0008339 | absent thyrotrophs | "absence of an anterior pituitary cell that produces thyroid-stimulating hormone" [MESH:A06.407.747.608.968] |
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Allelic Composition: Ss18tm1Adg/Ss18tm1Adg Genetic Background: B6.Cg-Ss18tm1Adg
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MP:0008340 | increased corticotroph cell number | "greater number of an anterior pituitary basophilic cell that produces adrenocorticotrophic hormone (ACTH)" [CL:0000467, MESH:A06.407.747.608.500] |
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Allelic Composition: Ss18tm1Adg/Ss18tm1Adg Genetic Background: B6.Cg-Ss18tm1Adg
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MP:0008347 | decreased gamma-delta T cell number | "reduced number of immature or mature T cells expressing an gamma-delta T cell receptor complex" [CL:0000798, ISBN:0781735149] |
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Allelic Composition: Prdm4tm1b(EUCOMM)Liz/Prdm4tm1b(EUCOMM)Liz Genetic Background: involves: 129S/SvEv * C57BL/6 * CBA
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MP:0008395 | abnormal osteoblast differentiation | "atypical production of or inability to produce bone-forming cells, which normally form an osseous matrix (osteoid) in which they become enclosed as an osteocytes" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 Genetic Background: involves: 129X1/SvJ * CD-1
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MP:0008396 | abnormal osteoclast differentiation | "atypical production of or inability to produce bone resorpting cells that remove bone tissue by degrading the mineralized matrix" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 Genetic Background: involves: 129X1/SvJ * CD-1
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Ppargtm1.1(tTA)Jmgr/Pparg+,Tg(tetO-cre)1Jaw/0,Tg(tetO-HIST1H2BJ/GFP)47Efu/0 Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Ctsktm1(cre)Ska/Ctsk+ Genetic Background: involves: 129X1/SvJ * C57BL/6NCrlj * CBA/JNCrlj
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Lyz2tm1(cre)Ifo/Lyz2+ Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Ppargtm1.1(tTA)Jmgr/Pparg+,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
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MP:0008414 | abnormal spatial reference memory | "anomaly in the ability to recall spatial location information from previous encounters or training sessions in order to naviagate or perform other behavior using such locational cues" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hoxb13tm2Mrc/Hoxb13tm2Mrc,Hoxd13tm1Mrc/Hoxd13tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0008463 | abnormal peripheral lymph node morphology | "any structural anomaly of the lymph nodes located outside the thoracic and abdominal cavities, such as the submandibular, prescapular, axillary, inguinal and popliteal lymph nodes" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0008464 | absent peripheral lymph nodes | "absence of the lymph nodes located outside the thoracic and abdominal cavities, such as the submandibular, prescapular, axillary, inguinal and popliteal lymph nodes" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0008730 | fused phalanges | "anomaly of the long bones of the digits resulting in some or all the bones being joined together" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Gt(ROSA)26Sortm1(Ctnnb1)Kem/Gt(ROSA)26Sortm1(Ctnnb1)Kem,Tg(Cdx1-cre)23Kem/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * FVB
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MP:0008794 | increased lens epithelium apopotosis | "increase in the number of lens epithelial cells undergoing programmed cell death" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1tm1Mmt,Tg(Cryaa-cre)10Mlr/0 Genetic Background: involves: 129X1/SvJ * FVB/N
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MP:0008797 | facial cleft | "a cleft resulting from incomplete merging or fusion of any of the embryonic facial processes that normally unite to form the face" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm1.2Wvv/Ctnnb1tm1.2Wvv Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
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MP:0008803 | abnormal placental labyrinth vasculature morphology | "any structural anomaly in blood vessels of the layer of the placenta where embryonic and maternal blood vessels interdigitate" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Sox9tm1Gsr/Sox9+,Tg(Col2a1-cre)1Bhr/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * SJL
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MP:0008841 | ruptured lens capsule | "a break or tear in the elastic, clear, membrane-like structure, that is outer most layer of the lens" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Apctm3Mmt/Apc+ Genetic Background: involves: 129X1/SvJ * C57BL/6N
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MP:0008858 | abnormal hair cycle anagen phase | "anomaly in the growth phase of the hair cycle" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Corintm2(cre)Bamo/Corin+,Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(KRT5-rtTA)#Glk/0,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(Krt1-15-cre/PGR)22Cot/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
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MP:0008859 | abnormal hair cycle catagen phase | "anomaly in the phase of the hair growth cycle during which cell proliferation ceases, the hair follicle shortens, and an anchored hair is produced" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Corintm2(cre)Bamo/Corin+,Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
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MP:0008860 | abnormal hair cycle telogen phase | "anomaly in the resting or quiescent phase of the hair growth cycle which follows cessation of proliferation (catagen) and preceeds hair loss" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Corintm2(cre)Bamo/Corin+,Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
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MP:0008868 | abnormal granulosa cell morphology | "any structural anomaly of a supporting cell for the developing female gamete in the ovary of mammals; granulosa cells form a single layer around the mammalian oocyte in the primordial ovarian follicle and advance to form a multilayered cumulus oophorus surrounding the ovum in the Graafian follicle" [MESH:A.05.360.319.114.630.535.200] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Ptentm1Hwu/Ptentm1Hwu,Tg(CYP19A1-cre)1Jri/0 Genetic Background: involves: 129S4/SvJae * 129X1/SvJ * C57BL/6
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MP:0008934 | absent choroid plexus | "absence of the fringe of the tela choroidea of the brain ventricles" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,H2afvTg(Wnt1-cre)11Rth/? Genetic Background: involves: 129/Sv * C57BL/6 * CBA
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MP:0009109 | decreased pancreas weight | "reduction in the average weight of the organ that secretes pancreatic juice into the duodenum and secretes glucagon and insulin into the bloodstream" [MESH:A03.734, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm4Wbm/Ctnnb1tm4Wbm,Tg(Pdx1-cre)6Tuv/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
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MP:0009139 | failure of Mullerian duct regression | "failure of the transient embryonic paramesonephric ducts, which normally develop into the oviduct, uterus, cervix and upper vagina in the female, to regress in the male; persistence of Mullerian ducts is typically consistent with a loss of anti-Mullerian hormone signaling and may allow development of the female reproductive tract in males" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Wnt4tm1.2Bhr/Wnt4tm1.2Bhr Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6J
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MP:0009142 | decreased prepulse inhibition | "decrease in the ability of a relatively mild stimulus to suppress the response to a strong, startle-eliciting stimulus" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hoxb13tm2Mrc/Hoxb13tm2Mrc,Hoxd13tm1Mrc/Hoxd13tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0009154 | pancreatic acinar hypoplasia | "underdevelopment or reduced size of the secretory units of the exocrine pancreas, where fluid containing digestive enzymes is produced, usually due to a decreased cell number" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm4Wbm/Ctnnb1tm4Wbm,Tg(Pdx1-cre)6Tuv/0 Genetic Background: involves: 129P2/OlaHsd * FVB/N
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MP:0009199 | abnormal external male genitalia morphology | "any structural anomaly of the external masculine genital organs, including the penis and scrotum" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm4Wbm/Ctnnb1tm4Wbm,Gli1tm3(cre/ERT2)Alj/Gli1+ Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac
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MP:0009219 | prostate intraepithelial neoplasia | "noninvasive prostate duct lesions that affect smaller caliber ducts" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Pbsn-cre)4Prb/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * DBA/2
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MP:0009220 | prostate adenocarcinoma | "malignant neoplasm arising from prostate tissue" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Pbsn-cre)4Prb/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * DBA/2
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MP:0009272 | decreased guard hair length | "reduction in the length of the long, straight truncal hairs that contain two air cells in the medulla" [ISBN:0-8493-8372-2 "Sundberg, JP (ed.) Handbook of Mouse Mutations with Skin and Hair Abnormalities"] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Corintm2(cre)Bamo/Corin+,Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
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MP:0009338 | increased splenocyte number | "increase in the expected number of cells of the spleen" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Ppargtm1.1(tTA)Jmgr/Pparg+,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
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MP:0009346 | decreased cancellous bone thickness | "thinner than normal bone with a lattice-like or spongy structure" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1+,Ppargtm1.1(tTA)Jmgr/Pparg+,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0009347 | increased cancellous bone thickness | "thicker than normal bone with a lattice-like or spongy structure" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Ppargtm1.1(tTA)Jmgr/Pparg+,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Ppargtm1.1(tTA)Jmgr/Pparg+,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
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MP:0009454 | impaired contextual conditioning | "decrease in the ability of an animal to learn and remember an association between an aversive experience (the unconditioned stimulus (US), usually a shock) and the neutral, unchanging environment (the conditioned stimulus (CS), or the environmental context in this case)" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hoxb13tm2Mrc/Hoxb13tm2Mrc,Hoxd13tm1Mrc/Hoxd13tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0009545 | abnormal dermis papillary layer | "any structural anomaly of the more superficial, thin layer of the dermis that interdigitates with the epidermis" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(KRT5-rtTA)#Glk/0,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N
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MP:0009550 | urinary bladder carcinoma | "a malignant neoplasm of the urinary bladder, arising from epithelial cells" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1tm1Mmt,Ptentm1Hwu/Ptentm1Hwu,Tg(Upk2-cre)6Xrw/0 Genetic Background: involves: 129S4/SvJae * 129X1/SvJ * FVB/N
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Ptentm1Hwu/Ptentm1Hwu,Tg(Upk2-cre)6Xrw/0 Genetic Background: involves: 129S4/SvJae * 129X1/SvJ * FVB/N
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Msx2-rtTA)885Lma/0,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129 * 129X1/SvJ * C57BL/6
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1tm1Mmt,Tg(Upk2-cre)6Xrw/0,Tg(Upk2-HRAS*Q61L)5Xrw/0 Genetic Background: involves: 129X1/SvJ * FVB/N
Allelic Composition: Cdkn1atm1Led/Cdkn1atm1Led,Ctnnb1tm1Mmt/Ctnnb1tm1Mmt,Tg(Upk2-cre)6Xrw/0 Genetic Background: involves: 129S6/SvEvTac * 129X1/SvJ * FVB/N
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1tm1Mmt,Krastm4Tyj/Kras+,Tg(Upk2-cre)6Xrw/0 Genetic Background: involves: 129S4/SvJae * 129X1/SvJ * FVB/N
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MP:0009612 | thick epidermis suprabasal layer | |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(KRT5-rtTA)#Glk/0,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N
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MP:0009629 | small brachial lymph nodes | "absence of the lymph nodes located along the brachial vein that receive drainage from most of the free upper limb and send efferent vessels to the central axillary lymph nodes" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0009632 | small axillary lymph nodes | "reduced size of the lymph nodes located around the axillary vein that receive lymphatic drainage from the upper or forelimb, scapular region and pectoral region" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0009634 | absent popliteal lymph nodes | "absence of the lymph nodes which drain the legs" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0009684 | abnormal spinal cord lateral motor column morphology | "any structural anomaly of the subclasses of motor neurons which innervate muscles in the limb; motor neurons in the lateral motor column are further organized into pools, each of which innervates a specific muscle in the limb" [PMID:8895454 "Tanabe Y, Jessell TM Diversity and pattern in the developing spinal cord. Science. 1996 Nov 15;274(5290):1115-23."] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Juptm1Ruiz/Juptm1Ruiz,Olig2tm1(cre)Tmj/Olig2+ Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ
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MP:0009685 | abnormal spinal cord motor column morphology | "any structural anomaly of the subclasses of motor neurons which are organized into longitudinally oriented columns that occupy distinct and, in some cases, discontinuous domains along the rostrocaudal axis of the spinal cord; motor neurons within a single column send their axons to a common peripheral target" [PMID:8895454 "Tanabe Y, Jessell TM Diversity and pattern in the developing spinal cord. Science. 1996 Nov 15;274(5290):1115-23."] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Juptm1Ruiz/Juptm1Ruiz,Olig2tm1(cre)Tmj/Olig2+ Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ
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MP:0009686 | abnormal spinal cord medial motor column morphology | "any structural anomaly of the subclasses of motor neurons which project their axons to axial muscles that lie close to the vertebral column; motor neurons in the lateral subdivision of the MMC project their axons to body wall muscles" [PMID:8895454 "Tanabe Y, Jessell TM Diversity and pattern in the developing spinal cord. Science. 1996 Nov 15;274(5290):1115-23."] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Olig2tm1(cre)Tmj/Olig2+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Juptm1Ruiz/Juptm1Ruiz,Olig2tm1(cre)Tmj/Olig2+ Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ
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MP:0009715 | thick epidermis stratum basale | "increased thickness of the deepest layer of the epidermis, which is composed of dividing stem cells and anchoring cells" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(KRT5-rtTA)#Glk/0,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N
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MP:0009890 | cleft secondary palate | "congenital fissure of the tissues normally uniting to form the secondary palate" [PMID:16680722] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1+,Osr2tm2(cre)Jian/Osr2+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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MP:0009902 | abnormal lateral nasal prominence morphology | "any structural anomaly of the lateral area of the two branches of a horseshoe-shaped mesenchymal swelling in the future nasal region of the embryo; it separates the olfactory pit from the developing eye and the ala of the nose/snout develops from it" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(Tcfap2a-cre)1Will/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0009903 | abnormal medial nasal prominence morphology | "any structural anomaly of the central area of the two limbs of a horseshoe-shaped mesenchymal swelling that lie medial to the olfactory placode or pit in the future nasal region of the embryo; it joins with the ipsilateral maxillary prominence in the formation of half of the upper jaw, and the nasal tip and philtrum of the upper lip develop from it" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Tcfap2a-cre)1Will/0 Genetic Background: involves: 129X1/SvJ * C57BL/6
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(Tcfap2a-cre)1Will/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0009932 | skin fibrosis | "invasion of fibrous connective tissue into the skin, often resulting from inflammation or injury" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1tm1Mmt,Tg(Mx1-cre)1Cgn/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Mx1-cre)1Cgn/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA
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MP:0009937 | abnormal neuron differentiation | "abnormal growth or development of the cells of the nervous system that receive, conduct, and transmit impulses" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm3Kba,H2afvTg(Wnt1-cre)11Rth/0 Genetic Background: involves: 129 * C57BL/6 * CBA/J
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MP:0009939 | abnormal hippocampus neuron morphology | |
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Allelic Composition: Hoxb13tm2Mrc/Hoxb13tm2Mrc,Hoxd13tm1Mrc/Hoxd13tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0010054 | hepatoblastoma | "a malignant neoplasm occurring primarily in the liver and composed of tissue resembling embryonic or fetal hepatic epithelium, or mixed epithelial and mesenchymal tissues" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1tm1Mmt,Tg(Mx1-cre)1Cgn/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Mx1-cre)1Cgn/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA
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MP:0010157 | abnormal small intestinal crypt cell proliferation | "anomaly in the ability of the cells that make up the tubular intestinal glands found in the mucosal membranes of the small intestine to undergo expansion by cell division" [MGI:jbubier "Jason Bubier, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+ Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ
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MP:0010234 | abnormal vibrissa follicle morphology | "any structural anomaly of one of the tubular invaginations of the epidermis enclosing the hair roots and from which grow the vibrissae located on the muzzle and face of many species" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0010254 | nuclear cataracts | "a lens opacity located in the dense, central part of the lens" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", ISBN:978-0-8493-0864-2 "Smith R.S. et al (ed.) Systematic Evaluation of the Mouse Eye: Anatomy, Pathology, and Biomethods"] |
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Allelic Composition: Apctm3Mmt/Apc+ Genetic Background: involves: 129X1/SvJ * C57BL/6N
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MP:0010275 | increased melanoma incidence | "greater than the expected number of malignant neoplasms, derived from melanocytes and occuring in pigmented tissues, in a specific population in a given time period" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Cdkn2atm1Rdp/Cdkn2atm1Rdp,Ptentm1Rps/Ptentm1Rps,Tg(Tyr-cre/ERT2)13Bos/0 Genetic Background: involves: 129/Sv * 129S1/Sv * C57BL/6J * FVB/N * SJL
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MP:0010279 | increased gastrointestinal tumor incidence | "greater than the expected number of tumors originating in the gastrointestinal system in a given population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm1.2Wvv/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
Allelic Composition: Apctm1Rsmi/Apc+,Ctnnb1tm1Wvv/Ctnnb1+,Tg(Fabp1-cre)1Jig/? Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * FVB/N
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MP:0010313 | increased osteoma incidence | "greater than the expected number of benign neoplasms derived from lamellar bone, in a specific population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tcf7tm1Cle/Tcf7+ Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ
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MP:0010318 | increased salivary gland tumor incidence | "greater than the expected number of neoplams in the salivary gland occurring in a specific population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Bmpr1atm2.1Bhr/Bmpr1atm2.1Bhr,Ctnnb1tm1Mmt/Ctnnb1+,Krt14tm1.1(cre)Wbm/Krt14+ Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * 129X1/SvJ
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MP:0010320 | increased pituitary gland tumor incidence | "greater than the expected number of neoplams in the pituitary gland occurring in a specific population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Sox2tm1.1(cre/ERT2)Jpmb/Sox2+ Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
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MP:0010357 | increased prostate gland tumor incidence | "greater than the expected number of neoplams in the prostate gland occurring in a specific population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Krastm1Bbd/Kras+,Tg(Pbsn-cre)4Prb/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2
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MP:0010864 | abnormal enamel knot morphology | "any structural anomaly of a transient cluster of cells in the central part of the dental epithelium facing the dental mesenchyme, which acts as an organizing center, providing positional information for tooth morphogenesis and regulating the growth of tooth cusps" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", PMID:8808404] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1+,Osr2tm2(cre)Jian/Osr2+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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MP:0010868 | increased bone trabecula number | "increased number of intersecting plates and spicules in cancellous bone which form a meshwork of intercommunicating spaces filled with blood vessels and marrow; in mature bone, the trabeculae are aligned in parallel with the lines of major compressive or tensile force" [http://www.dorlands.com/ "Dorland s Illustrated Medical Dictionary, 31st edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Ppargtm1.1(tTA)Jmgr/Pparg+,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Ppargtm1.1(tTA)Jmgr/Pparg+,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
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MP:0010869 | decreased bone trabecula number | "decreased number of intersecting plates and spicules in cancellous bone which form a meshwork of intercommunicating spaces filled with blood vessels and marrow; in mature bone, the trabeculae are aligned in parallel with the lines of major compressive or tensile force" [http://www.dorlands.com/ "Dorland s Illustrated Medical Dictionary, 31st edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1+,Ppargtm1.1(tTA)Jmgr/Pparg+,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0010873 | decreased trabecular bone mass | "reduced total amount of trabecular bone tissue contained in the skeleton" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1+,Ppargtm1.1(tTA)Jmgr/Pparg+,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0010875 | increased bone volume | "increased amount of space occupied by bone tissue in the skeleton" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(Tek-cre)1Ywa/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Ppargtm1.1(tTA)Jmgr/Pparg+,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Ctsktm1(cre)Ska/Ctsk+ Genetic Background: involves: 129X1/SvJ * C57BL/6NCrlj * CBA/JNCrlj
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Lyz2tm1(cre)Ifo/Lyz2+ Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Ppargtm1.1(tTA)Jmgr/Pparg+,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
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MP:0010878 | increased trabecular bone volume | "increase in the amount of space occupied by trabecular bone tissue in the skeleton" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Ppargtm1.1(tTA)Jmgr/Pparg+,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Ppargtm1.1(tTA)Jmgr/Pparg+,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
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MP:0010879 | decreased trabecular bone volume | "decrease in the amount of space occupied by trabecular bone tissue in the skeleton" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Ctsktm1(cre)Ska/Ctsk+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrlj * CBA/JNCrlj
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1+,Ctsktm1(cre)Ska/Ctsk+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrlj * CBA/JNCrlj
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Lyz2tm1(cre)Ifo/Lyz2+ Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1+,Lyz2tm1(cre)Ifo/Lyz2+ Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1+,Tg(Tek-cre)1Ywa/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1+,Ppargtm1.1(tTA)Jmgr/Pparg+,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0010907 | absent lung buds | "absence of the blunt end of the respiratory diverticulum which normally grows ventrally out of the proximal end of the foregut, then extends caudally and divides into two, forming the origins of the bronchial tree" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Shhtm1(EGFP/cre)Cjt/Shh+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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MP:0010939 | abnormal mandibular prominence morphology | |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Tcfap2a-cre)1Will/0 Genetic Background: involves: 129X1/SvJ * C57BL/6
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(Tcfap2a-cre)1Will/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Ctnnb1tm1.2Wvv/Ctnnb1tm1.2Wvv Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
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MP:0010940 | abnormal maxillary prominence morphology | |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Tcfap2a-cre)1Will/0 Genetic Background: involves: 129X1/SvJ * C57BL/6
Allelic Composition: Ctnnb1tm1.2Wvv/Ctnnb1tm1.2Wvv Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
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MP:0010964 | increased compact bone volume | |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Ppargtm1.1(tTA)Jmgr/Pparg+,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Ppargtm1.1(tTA)Jmgr/Pparg+,Tg(tetO-cre)1Jaw/0 Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
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MP:0011083 | complete lethality at weaning | "premature death at weaning age of all organisms of a given genotype in a population, often due to the inability to make the transition to solid food" [MGI:csmith] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tcf7tm1Cle/Tcf7+ Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ
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MP:0011085 | complete postnatal lethality | "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Cdh16-cre)91Igr/0 Genetic Background: involves: 129X1/SvJ * ICR
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MP:0011087 | complete neonatal lethality | "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith] |
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Allelic Composition: Apoetm1Bres/Apoetm1Bres,Cx3cr1tm1Ifc/Cx3cr1tm1Ifc Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
Allelic Composition: Ctnnb1tm1Yy/Ctnnb1tm1Yy,Tg(Col2a1-cre)1Bhr/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6
Allelic Composition: Ctnnb1tm1Yy/Ctnnb1tm1Yy,Tg(Prnp-GFP/cre)1Blw/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6
Allelic Composition: Ctnnb1tm4Wbm/Ctnnb1tm4Wbm,Tg(KRT14-cre)1Efu/0 Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(Tcfap2a-cre)1Will/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Olig2tm1(cre)Tmj/Olig2+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(Hoxb7-cre)5526Cmb/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Gt(ROSA)26Sortm1(Ctnnb1)Kem/Gt(ROSA)26Sortm1(Ctnnb1)Kem,H2afvTg(Wnt1-cre)11Rth/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6J * CBA/J
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Tg(Foxn1-cre)1Tbo/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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MP:0011089 | complete perinatal lethality | "death of all organisms of a given genotype in a population within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 Genetic Background: involves: 129X1/SvJ * CD-1
Allelic Composition: Ctnnb1tm1.2Wvv/Ctnnb1tm1.2Wvv Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Gt(ROSA)26Sortm1(Ctnnb1)Kem/Gt(ROSA)26Sortm1(Ctnnb1)Kem,Tg(Cdx1-cre)23Kem/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * FVB
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MP:0011091 | complete prenatal lethality | "death of all organisms of a given genotype in a population between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,H2afvTg(Wnt1-cre)11Rth/? Genetic Background: involves: 129/Sv * C57BL/6 * CBA
Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1tm1(Nfkbia)Rsu Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Gt(ROSA)26Sortm1(Ctnnb1)Kem/Gt(ROSA)26Sor+,Tg(Zp3-cre)93Knw/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6J
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Gt(ROSA)26Sortm1(Ctnnb1)Kem/Gt(ROSA)26Sortm1.1(Ctnnb1)Kem,Edil3Tg(Sox2-cre)1Amc/Edil3+ Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * CBA
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Edil3Tg(Sox2-cre)1Amc/Edil3+ Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * CBA
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Tg(Zp3-cre)93Knw/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6J
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Gt(ROSA)26Sortm1(Ctnnb1)Kem/Gt(ROSA)26Sor+,Tg(Cdx1-cre)23Kem/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * FVB
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Gt(ROSA)26Sortm1(Ctnnb1)Kem/Gt(ROSA)26Sor+,H2afvTg(Wnt1-cre)11Rth/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6J * CBA/J
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MP:0011092 | complete embryonic lethality | "death of all organisms of a given genotype in a population within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith] |
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Allelic Composition: Scn8amed-J/Scn8amed-J,Scnm1s/Scnm1s Genetic Background: involves: C57BL/6J
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Ptentm1Hwu/Ptentm1Hwu,Tg(Cdh5-cre)7Mlia/0 Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * BALB/c * C57BL/6 * FVB/N
Allelic Composition: Apctm1Rak/Apc+,Ctnnb1tm1.2Wvv/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
Allelic Composition: Apctm2Rfo/Apc+,Ctnnb1tm1.2Wvv/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Tek-cre)1Ywa/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * SJL
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MP:0011096 | complete embryonic lethality before somite formation | "death of all organisms of a given genotype in a population between the point of implantation and somite formation (Mus: E4.5 to less than E8)" [MGI:csmith] |
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Allelic Composition: Scn8amed-J/Scn8amed-J,Scnm1s/Scnm1s Genetic Background: involves: C57BL/6J
Allelic Composition: ApcMin/ApcMin,Ctnnb1tm4.1Wbm/Ctnnb1+ Genetic Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2Kba/Ctnnb1tm2Kba Genetic Background: involves: 129S6/SvEvTac * C57BL/6
Allelic Composition: Ctnnb1tm3Kba/Ctnnb1tm3Kba Genetic Background: involves: 129S6/SvEvTac * C57BL/6
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MP:0011098 | complete embryonic lethality during organogenesis | "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith] |
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Allelic Composition: Prrx1tm1Tex/Prrx1tm1Tex,Prrx2tm1Hubr/Prrx2tm1Hubr Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB
Allelic Composition: Ctnnb1tm1Wbm/Ctnnb1tm1Wbm Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2Wbm/Ctnnb1tm2Wbm Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm3Wbm/Ctnnb1tm3Wbm Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Tg(Tek-cre)1Ywa/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Kdrtm1(cre)Sato/Kdr+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Juptm1Ruiz/Juptm1Ruiz,Olig2tm1(cre)Tmj/Olig2+ Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ
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MP:0011099 | complete lethality throughout fetal growth and development | "death of all organisms of a given genotype in a population between the completion of organogenesis and birth (Mus: E14 to approximately E18.5)" [MGI:csmith] |
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Allelic Composition: Thtm1.1Ich/Thtm1.1Ich Genetic Background: Not Specified
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MP:0011100 | complete preweaning lethality | "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith] |
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Allelic Composition: Ctnnb1tm2.1Kem/Ctnnb1+,Sall4Gt(W097E01)Flo/Sall4+ Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6
Allelic Composition: Ctnnb1Bfc/Ctnnb1Bfc Genetic Background: either: (involves: BALB/cCrl * C3H/HeNCrl) or (involves: BALB/cCrl * C3H/HeNCrl * C57BL/6)
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MP:0011101 | partial prenatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2(Nfkbia)Rsu/Ctnnb1+,Tg(CMV-cre)1Cgn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(Tek-cre)1Ywa/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
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MP:0011102 | partial embryonic lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith] |
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Allelic Composition: Rspo1tm1Mcch/Rspo1tm1Mcch Genetic Background: involves: 129 * C57BL/6J
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MP:0011108 | partial embryonic lethality during organogenesis | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Tcfap2a-cre)1Will/0 Genetic Background: involves: 129X1/SvJ * C57BL/6
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MP:0011109 | partial lethality throughout fetal growth and development | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between the completion of organogenesis and birth (Mus: E14 to approximately E18.5)" [MGI:csmith] |
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Allelic Composition: Psen1tm1Jzt/Psen1tm1Jzt Genetic Background: involves: C57BL/6 * CBA
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Tcfap2a-cre)1Will/0 Genetic Background: involves: 129X1/SvJ * C57BL/6
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MP:0011110 | partial preweaning lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith] |
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Allelic Composition: Ctnnb1Bfc/Ctnnb1+ Genetic Background: either: (involves: BALB/cCrl * C3H/HeNCrl) or (involves: BALB/cCrl * C3H/HeNCrl * C57BL/6)
Allelic Composition: Ctnnb1Bfc/Ctnnb1+,Dkk1tm1Lmgd/Dkk1+ Genetic Background: either: (involves: 129/Sv * BALB/cCrl * C3H/HeNCrl) or (involves: 129/Sv * BALB/cCrl * C3H/HeNCrl * C57BL/6)
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MP:0011194 | abnormal hair follicle physiology | "any functional anomaly of the invagination of the epidermis from which the hair shaft develops" [MESH:A10.272.497.500, MGI:mnk] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Corintm2(cre)Bamo/Corin+,Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
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MP:0011195 | increased hair follicle apoptosis | "greater than expected levels of programmed cell death of cells in the epidermis from which the hair shaft develops" [MGI:mnk] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Corintm2(cre)Bamo/Corin+,Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
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MP:0011290 | decreased nephron number | "reduction in the total number of filtering units of the kidney" [MGI:anna] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(Hoxb7-cre)5526Cmb/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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MP:0011298 | ureter hypoplasia | "underdevelopment or reduced size of the ureter, usually due to a reduced number of cells" [MGI:anna] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1tm1Mmt,Tcf21tm1(cre)Seq/Tcf21+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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MP:0011386 | increased metanephric mesenchyme apoptosis | "increase in the number of cells of the metanephric mesenchyme (MM) undergoing programmed cell death; usually due to failure of MM cells to interact with the ureteric bud (UB) tips after UB invasion" [MGI:anna] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(Hoxb7-cre)5526Cmb/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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MP:0011407 | absent nephrogenic zone | "absence of the region found at the periphery of the developing metanephros within which the metanephric mesenchyme aggregates around the tips of the ureteric tree to form the nephrons;in rodents including mice, this region normally persists for a few days postnatally, although it is lost in humans by 36 weeks of gestation" [PMID:17452023] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(Hoxb7-cre)5526Cmb/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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MP:0011441 | decreased kidney cell proliferation | "decrease in the expansion rate of any kidney cell population by cell division" [MGI:anna] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(Hoxb7-cre)5526Cmb/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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MP:0011496 | abnormal head size | "anomaly in the average size of the portion of the body containing the brain and organs of sight, hearing, taste, and smell" [MGI:csmith] |
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Allelic Composition: Ctnnb1Bfc/Ctnnb1Bfc Genetic Background: either: (involves: BALB/cCrl * C3H/HeNCrl) or (involves: BALB/cCrl * C3H/HeNCrl * C57BL/6)
Allelic Composition: Ctnnb1Bfc/Ctnnb1+,Lrp6Gw/Lrp6+ Genetic Background: either: (involves: 101/H * BALB/cCrl * C3H) or (involves: 101/H * BALB/cCrl * C3H * C57BL/6)
Allelic Composition: Ctnnb1Bfc/Ctnnb1+,Dkk1tm1Lmgd/Dkk1+,Lrp6Gw/Lrp6+ Genetic Background: either: (involves: 101/H * 129/Sv * BALB/cCrl * C3H) or (involves: 101/H * 129/Sv * BALB/cCrl * C3H * C57BL/6)
Allelic Composition: Ctnnb1Bfc/Ctnnb1Bfc,Dkk1tm1Lmgd/Dkk1+ Genetic Background: either: (involves: 129/Sv * BALB/cCrl * C3H/HeNCrl) or (involves: 129/Sv * BALB/cCrl * C3H/HeNCrl * C57BL/6)
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MP:0011523 | thin placenta labyrinth | "decrease in the width of the structure where embryonic blood vessels are surrounded by trophoblast cells and maternal blood" [MGI:csmith] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Tg(Tek-cre)1Ywa/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
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MP:0011712 | absent osteoblast differentiation | |
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Allelic Composition: Ctnnb1tm1Yy/Ctnnb1tm1.1Yy,Ptch1tm1Yy/Ptch1tm1.1Yy,Tg(Col2a1-cre)1Bhr/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
Allelic Composition: Ctnnb1tm1Max/Ctnnb1tm2Kem,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Twist2tm1(cre)Dor/Twist2+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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MP:0011846 | decreased kidney collecting duct number | "smaller than expected number of the kidney ducts that collect urine from the distal convoluted tubules, merge and become larger as they descend from the renal cortex into the medulla, and respond to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance" [MGI:anna] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(Hoxb7-cre)5526Cmb/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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MP:0012087 | absent midbrain | "absence of the brain region derived from the middle of the three cerebral vesicles of the embryo; this region controls sensory and motor functions in the adult, including eye movement and coordination of auditory and visual reflexes" [MGI:anna] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,H2afvTg(Wnt1-cre)11Rth/? Genetic Background: involves: 129/Sv * C57BL/6 * CBA
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+,H2afvTg(Wnt1-cre)11Rth/0 Genetic Background: involves: 129 * C57BL/6 * CBA/J
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MP:0012110 | increased hair follicle number | "greater number of the epidermal invaginations from which the hair shaft develops" [MGI:monikat] |
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Allelic Composition: Bmpr1atm2.1Bhr/Bmpr1atm2.1Bhr,Ctnnb1tm1Mmt/Ctnnb1+,Krt14tm1.1(cre)Wbm/Krt14+ Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * 129X1/SvJ
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MP:0012133 | absent midbrain-hindbrain boundary | "absence of the midbrain-hindbrain domain of the embryonic brain that is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages; normally, an organizing center located at the boundary patterns the midbrain and hindbrain primordia of the neural plate" [MGI:anna] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,H2afvTg(Wnt1-cre)11Rth/? Genetic Background: involves: 129/Sv * C57BL/6 * CBA
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,H2afvTg(Wnt1-cre)11Rth/0 Genetic Background: involves: 129 * C57BL/6 * CBA/J
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm3Kba,Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+,H2afvTg(Wnt1-cre)11Rth/0 Genetic Background: involves: 129 * C57BL/6 * CBA/J
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+,H2afvTg(Wnt1-cre)11Rth/0 Genetic Background: involves: 129 * C57BL/6 * CBA/J
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MP:0012141 | absent hindbrain | "absence of the part of the brain developed from the posterior of the three primary brain vesicles of the embryonic neural tube from which the metencephalon and myelencephalon are derived; the metencephalon (anterior part of the embryonic hindbrain), gives rise to the cerebellum and pons while the myelencephalon (posterior portion of the embryonic hindbrain) gives rise to the medulla oblongata" [MGI:anna] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+,H2afvTg(Wnt1-cre)11Rth/0 Genetic Background: involves: 129 * C57BL/6 * CBA/J
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MP:0012157 | rostral body truncation | "rostral part of body truncated; typically with the caudal portion of the body relatively normal" [MGI:csmith] |
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Allelic Composition: Apctm1Rak/Apc+,Ctnnb1tm1.2Wvv/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
Allelic Composition: Apctm2Rfo/Apc+,Ctnnb1tm1.2Wvv/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
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MP:0012163 | abnormal dental mesenchyme morphology | "any structural anomaly of the mesenchyme enclosed by dental organ" [MGI:anna] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1tm1Mmt,Osr2tm5(cre)Jian/Osr2+ Genetic Background: involves: 129X1/SvJ
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MP:0012300 | abnormal umbilical cord blood vessel morphology | "any structural anomaly of the three blood vessels, usually one large umbilical vein and two small umbilical arteries, buried within Wharton s jelly, that transport blood to and from the placenta, where exchange between the mother and fetus takes place; the umbilical vein carries oxygenated, nutrient-rich blood from the placenta to the fetus, and the umbilical arteries carry deoxygenated, nutrient-depleted blood from the fetus to the placenta" [MGI:anna] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Tg(Tek-cre)1Ywa/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
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MP:0012306 | enhanced spatial learning | "enhanced ability to ascertain or acquire spatial location information in order to improve navigation or other behavior using such location cues" [MGI:csmith] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Pvalbtm1(cre)Arbr/Pvalb+ Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0012318 | slow extinction of fear memory | "impaired ability or inability to extinguish aversive memories associated with a traumatic incident" [http://www.mpipsykl.mpg.de/en/research/themes/depression/wotjak_02/] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Pvalbtm1(cre)Arbr/Pvalb+ Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0012411 | increased granulosa cell tumor incidence | "greater than the expected number of neoplasms derived from somatic cells of the sex cord in the ovary a given population in a given time period" [http://orcid.org/0000-0001-5208-3432] |
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Allelic Composition: Amhr2tm3(cre)Bhr/Amhr2+,Ctnnb1tm1Mmt/Ctnnb1+,Ptentm1Hwu/Ptentm1Hwu Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(CYP19A1-cre)1Jri/0 Genetic Background: involves: 129X1/SvJ * C57BL/6
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Krastm4Tyj/Kras+,Tg(CYP19A1-cre)1Jri/0 Genetic Background: involves: 129S4/SvJae * 129X1/SvJ * C57BL/6
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Ptentm1Hwu/Ptentm1Hwu,Tg(CYP19A1-cre)1Jri/0 Genetic Background: involves: 129S4/SvJae * 129X1/SvJ * C57BL/6
Allelic Composition: Amhr2tm3(cre)Bhr/Amhr2+,Ctnnb1tm1Mmt/Ctnnb1+ Genetic Background: involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Krastm4Tyj/Kras+,Amhr2tm3(cre)Bhr/Amhr2+ Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
Allelic Composition: Amhr2tm3(cre)Bhr/Amhr2+,Ctnnb1tm1Mmt/Ctnnb1+,Ptentm1Hwu/Ptentm1Hwu Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
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MP:0012467 | increased striatum area | "greater size of a large cluster of dopaminergic nerve cells, consisting of the caudate nucleus and the putamen, that controls movement, balance, and walking" [ISBN:0838580343, MGI:csmith] |
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Allelic Composition: Hoxb13tm2Mrc/Hoxb13tm2Mrc,Hoxd13tm1Mrc/Hoxd13tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0012516 | absent metencephalon | "absence of the anterior part of the developing vertebrate hindbrain or the corresponding part of the adult brain normally composed of the cerebellum and the pons Varolii" [MGI:anna] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,H2afvTg(Wnt1-cre)11Rth/? Genetic Background: involves: 129/Sv * C57BL/6 * CBA
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MP:0012568 | decreased mammary gland tumor incidence in breeding females | "less than the expected number of neoplams in the mammary gland in female organisms that are actively mating and producing offspring" [http://orcid.org/0000-0001-5208-3432] |
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Allelic Composition: Trp63tm2.2Elrf/Trp63+ Genetic Background: Not Specified
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MP:0012570 | increased mammary gland tumor incidence in breeding females | "greater than the expected number of neoplams in the mammary gland in female organisms that are actively mating and producing offspring" [http://orcid.org/0000-0001-5208-3432] |
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Allelic Composition: Slc1a2tm1.1Ncd/Slc1a2tm1.1Ncd,Tg(Pdx1-cre)1Heed/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Wap-cre)11738Mam/0 Genetic Background: FVB.Cg-Ctnnb1tm1Mmt Tg(Wap-cre)11738Mam
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MP:0012571 | increased mammary gland tumor incidence in virgin females | |
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Allelic Composition: Slc1a2tm1.1Ncd/Slc1a2tm1.1Ncd,Tg(Pdx1-cre)1Heed/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
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MP:0012739 | abnormal anterior primitive streak morphology | "any structural anomaly of the anterior region of the vertebrate primitive streak which gives rise to the axial and paraxial mesoderm, the definitive endoderm, the primitive groove, and the primitive node" [MGI:anna] |
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Allelic Composition: Ctnnb1tm2.1Kem/Ctnnb1+,Sall4Gt(W097E01)Flo/Sall4+ Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6
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MP:0013180 | truncated tail bud | "shortened tail bud that terminates in a blunt end (instead of a tapered end)" [MGI:anna] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2.1Kem,Gt(ROSA)26Sortm1(Ctnnb1)Kem/Gt(ROSA)26Sor+,Tg(Cdx1-cre)23Kem/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * FVB
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MP:0013445 | Harderian gland atrophy | "acquired diminution of the size of the sebaceous gland that is located behind the eyeball and excretes fluid that facilitates movement of the nictitating membrane, associated with wasting as from death and reabsorbtion of cells, diminished cellular proliferation, decreased cellular volume, pressure, ischemia, malnutrition, reduced function or malfunction, or hormonal changes" [MGI:Anna] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2(Nfkbia)Rsu/Ctnnb1+,Tg(CMV-cre)1Cgn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6
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MP:0013466 | keratoconjunctivitis sicca | "inflammation of the cornea and conjuctiva caused by eye dryness which, in turn, is caused by either decreased tear production or increased tear film evaporation" [MGI:Anna] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Ctnnb1tm2(Nfkbia)Rsu/Ctnnb1+,Tg(CMV-cre)1Cgn/0 Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6
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MP:0013486 | decreased Paneth cell number | "fewer than normal numbers of the large secretory cells containing coarse granules found at the base of the crypts of Lieberkuhn in the small intestine" [MGI:Anna] |
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Allelic Composition: Sox10gt/Sox10+ Genetic Background: HYIII/LeJ
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MP:0013733 | squamous metaplasia of bulbourethral gland | "a benign non-cancerous transformation of the bulbourethral glandular epithelium into stratified squamous epithelium; keratinization may be present" [MGI:Anna, PMID:19117991] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Krastm1Bbd/Kras+,Tg(Pbsn-cre)4Prb/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Pbsn-cre)4Prb/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * DBA/2
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MP:0013734 | squamous metaplasia of preputial gland | "a benign non-cancerous transformation of the preputial glandular epithelium into stratified squamous epithelium; keratinization may be present" [MGI:Anna, PMID:19117991] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Pbsn-cre)4Prb/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * DBA/2
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MP:0013735 | squamous metaplasia of urethral gland | "a benign non-cancerous transformation of the urethral glandular epithelium into stratified squamous epithelium; keratinization may be present" [MGI:Anna, PMID:19117991] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Krastm1Bbd/Kras+,Tg(Pbsn-cre)4Prb/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2
Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Pbsn-cre)4Prb/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * DBA/2
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MP:0013745 | abnormal eyelid margin morphology | "any structural anomaly of the confluence of the mucosal surface of the conjunctiva, the edge of the orbicularis, and the cutaneous epithelium" [http://one.aao.org/bcscsnippetdetail.aspx?id=2b7328d7-5eb2-4df3-812a-031ff1c1f904, http://www.medilexicon.com/medicaldictionary.php?s=palpebral+margins, MGI:Anna] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0013818 | abnormal oral cavity morphology | "any structural anomaly of the anatomical cavity at the start of the digestive tract that is enclosed by the mouth" [UBERON:0000167] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Tcfap2a-cre)1Will/0 Genetic Background: involves: 129X1/SvJ * C57BL/6
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MP:0013945 | abnormal elbow joint morphology | |
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Allelic Composition: Ctnnb1tm1Yy/Ctnnb1tm1.1Yy,Ptch1tm1Yy/Ptch1tm1.1Yy,Tg(Col2a1-cre)1Bhr/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
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MP:0014077 | ectopic Paneth cells | "abnormal position of the large secretory cells containing coarse granules normally confined to the base of the crypts of Lieberkuhn in the small intestine" [MGI:Anna] |
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Allelic Composition: Sox10gt/Sox10+ Genetic Background: HYIII/LeJ
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MP:0014103 | increased chondrocyte apoptosis | "increased number of chondrocytes undergoing programmed cell death" [MGI:csmith] |
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Allelic Composition: Ctnnb1tm1Yy/Ctnnb1tm1.1Yy,Tg(Col2a1-cre)1Bhr/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
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MP:0020137 | decreased bone mineralization | "decrease in the rate at which minerals are deposited into bone" [] |
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Allelic Composition: Ctnnb1tm1Yy/Ctnnb1tm1.1Yy,Ptch1tm1Yy/Ptch1tm1.1Yy,Tg(Col2a1-cre)1Bhr/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
Allelic Composition: Ctnnb1tm1Yy/Ctnnb1tm1.1Yy,Tg(Col2a1-cre)1Bhr/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
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MP:0020288 | supernumerary limbs | "more than the expected number of limbs differentiate during early embryogenesis" [GOC:NV] |
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Allelic Composition: Gt(ROSA)26Sortm2(Sp8)Lma/Gt(ROSA)26Sor+,Sp8tm1Smb/Sp8tm1Smb,Tg(Msx2-cre)5Rem/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
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MP:0020395 | abnormal response to social novelty | "any anomaly in the interaction of an individual with a familiar versus a novel individual of the same species; in mouse the typical behavior is is for increased interaction with the novel individual" [PMID:23280234] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Pvalbtm1(cre)Arbr/Pvalb+ Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0020526 | enlarged thalamus | "increased size of the thalamus" [MGI:smb] |
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Allelic Composition: Hoxb13tm2Mrc/Hoxb13tm2Mrc,Hoxd13tm1Mrc/Hoxd13tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0030252 | narrow frontonasal prominence | "decreased width of the unpaired embryonic process that is formed from the tissues surrounding the forebrain vesicle and develops into the forehead and bridge of the nose/snout" [MGI:anna] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(Tcfap2a-cre)1Will/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0030302 | abnormal maxillary zygomatic process morphology | "any structural anomaly of the rough triangular eminence situated at the angle of separation of the anterior, zygomatic, and orbital surfaces; in front, it forms part of the anterior surface; behind, it is concave, and forms part of the infratemporal fossa; above, it is rough and serrated for articulation with the zygomatic bone; below, it presents the prominent arched border which marks the division between the anterior and infratemporal surfaces" [https://en.wikipedia.org/wiki/Zygomatic_process_of_maxilla] |
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Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(Tcfap2a-cre)1Will/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0030313 | abnormal face development | "any anomaly in the process in which the anatomical structures of the face are generated and organized" [GO:0060325] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Tcfap2a-cre)1Will/0 Genetic Background: involves: 129X1/SvJ * C57BL/6
Allelic Composition: Ctnnb1tm2Kem/Ctnnb1tm2Kem,Tg(Tcfap2a-cre)1Will/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0030324 | abnormal anterior head development | "any anomaly in the process in which the anatomical structures of the anterior part of the head are generated and organized" [GO:0097065, MGI:anna] |
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Allelic Composition: Ctnnb1tm1.2Wvv/Ctnnb1tm1.2Wvv Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
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MP:0030541 | misaligned incisors | "abnormal alignment of the upper and lower incisor teeth, usually resulting in malocclusion; in gnawing rodents, where incisors are rootless and grow continually, signs of incisor malocclusion include uneven wear patterns, sloping of the cutting edges, fractured teeth, altered pigmentation, and obvious pathological overgrowth of the incisors" [HP:0011062, https://books.google.com/books?isbn=0323394302, PMID:19622764] |
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Allelic Composition: Ctnnb1tm1(Nfkbia)Rsu/Ctnnb1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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