ENSMUSG00000070643


Mus musculus

Features
Gene ID: ENSMUSG00000070643
  
Biological name :Sox13
  
Synonyms : Q04891 / Sox13 / Transcription factor SOX-13
  
Possible biological names infered from orthology : Q9UN79 / SRY-box 13
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: E4
Gene start: 133382303
Gene end: 133424377
  
Corresponding Affymetrix probe sets: 10357790 (MoGene1.0st)   1450191_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000092130
Ensembl peptide - ENSMUSP00000119729
Ensembl peptide - ENSMUSP00000122980
NCBI entrez gene - 20668     See in Manteia.
MGI - MGI:98361
RefSeq - XM_011247945
RefSeq - NM_011439
RefSeq - XM_006529276
RefSeq - XM_006529277
RefSeq Peptide - NP_035569
swissprot - D3Z7I3
swissprot - Q04891
Ensembl - ENSMUSG00000070643
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sox13ENSDARG00000030297Danio rerio
 SOX13ENSGALG00000000583Gallus gallus
 SOX13ENSG00000143842Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Sox5 / P35710 / SRY (sex determining region Y)-box 5 / P35711* / SRY-box 5*ENSMUSG0000004154046
Sox6 / P40645 / SRY (sex determining region Y)-box 6 / P35712* / SRY-box 6*ENSMUSG0000005191042
Sox30 / Q8CGW4 / Transcription factor SOX-30 / O94993* / SRY-box 30*ENSMUSG0000004048918


Protein motifs (from Interpro)
Interpro ID Name
 IPR009071  High mobility group box domain
 IPR029547  Transcription factor SOX-13
 IPR036910  High mobility group box domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0045586 regulation of gamma-delta T cell differentiation IDA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm ISO
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IDA


Pathways (from Reactome)
Pathway description
Deactivation of the beta-catenin transactivating complex


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Hprttm1Isrd/Y
Genetic Background: involves: C57BL/6

 MP:0002089 abnormal postnatal growth/weight/body size "increased or decreased average body size, weight or growth characteristic abnormalities manifesting after birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Hprttm1Isrd/Y
Genetic Background: involves: C57BL/6

 MP:0002590 increased mean corpuscular volume "greater than the average amount of space occupied by each red blood cell, calculated from the hematocrit and red cell count, in erythrocyte indices" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Smoc1tm1a(EUCOMM)Wtsi/Smoc1+
Genetic Background: C57BL/6N-Smoc1tm1a(EUCOMM)Wtsi/H

 MP:0005348 increased T cell proliferation "increased clonal expansion of naive T cells in response to stimuli" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Hprttm1Isrd/Y
Genetic Background: involves: C57BL/6

 MP:0005641 increased mean corpuscular hemoglobin concentration "greater than the normal Hgb/Hct; the average hemoglobin concentration in a given volume of packed red cells, calculated from the hemoglobin therein and the hematocrit, in erythrocyte indices" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:8936]
Show

Allelic Composition: Smoc1tm1a(EUCOMM)Wtsi/Smoc1+
Genetic Background: C57BL/6N-Smoc1tm1a(EUCOMM)Wtsi/H

 MP:0008347 decreased gamma-delta T cell number "reduced number of immature or mature T cells expressing an gamma-delta T cell receptor complex" [CL:0000798, ISBN:0781735149]
Show

Allelic Composition: Hprttm1Isrd/Y
Genetic Background: involves: C57BL/6

Allelic Composition: Sox13tm1Jskg/Sox13+
Genetic Background: involves: C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000006932 Ctnnb1 / Q02248 / Catenin beta-1 / P35222*  / complex / reaction
 ENSMUSG00000027985 Lef1 / P27782 / Lymphoid enhancer-binding factor 1 / Q9UJU2*  / complex / reaction
 ENSMUSG00000024985 Q924A0 / Tcf7l2 / transcription factor 7 like 2, T cell specific, HMG box / Q9NQB0* / transcription factor 7 like 2*  / complex / reaction






 

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