MP:0000074 | abnormal neurocranium morphology | "malformed bones of the skull enclosing the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:55583] |
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Allelic Composition: Cdkn2atm1Rdp/Cdkn2atm1Rdp,Tg(Mt1-HGFSF)19Lmb/0 Genetic Background: involves: 129/Sv * C57BL/6J * FVB/N * SJL
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MP:0000157 | abnormal sternum morphology | "malformed long flat bone of the chest; articulates with clavicle and first seven rib pairs" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:19212] |
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Allelic Composition: Cdkn2atm1Rdp/Cdkn2atm1Rdp,Tg(Mt1-HGFSF)19Lmb/0 Genetic Background: involves: 129/Sv * C57BL/6J * FVB/N * SJL
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MP:0000163 | abnormal cartilage morphology | "anomalous structure or development of the nonvascular, resilient, flexible connective tissue found primarily in joints, walls of the throax, and tubular structures, but which also comprises most of the skeleton in early fetal life " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Cdkn2atm1Rdp/Cdkn2atm1Rdp,Tg(Mt1-HGFSF)19Lmb/0 Genetic Background: involves: 129/Sv * C57BL/6J * FVB/N * SJL
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MP:0000164 | abnormal cartilage development | "anomalous formation of the nonvascular, resilient, flexible connective tissue found primarily in joints, walls of the throax, and tubular structures, but which also comprises most of the skeleton in early fetal life " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Sox6tm2.2Vlf/Sox6tm2.2Vlf Genetic Background: involves: 129 * C57BL/6J
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MP:0000166 | abnormal chondrocyte morphology | "anomalous structure, organization, or differentiation of nondividing cartilage cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:40203] |
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Allelic Composition: Cdkn2atm1Rdp/Cdkn2atm1Rdp,Tg(Mt1-HGFSF)19Lmb/0 Genetic Background: involves: 129/Sv * C57BL/6J * FVB/N * SJL
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MP:0000445 | short snout | "reduced length of the anterior facial part of the muzzle" [J:53370] |
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Allelic Composition: Cdkn2atm1Rdp/Cdkn2atm1Rdp,Tg(Mt1-HGFSF)19Lmb/0 Genetic Background: involves: 129/Sv * C57BL/6J * FVB/N * SJL
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MP:0000547 | short limbs | "reduced average length of the extremities" [MGI:CLS, J:61509] |
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Allelic Composition: Cdkn2atm1Rdp/Cdkn2atm1Rdp,Tg(Mt1-HGFSF)19Lmb/0 Genetic Background: involves: 129/Sv * C57BL/6J * FVB/N * SJL
Allelic Composition: Sox5tm2Vlf/Sox5tm2Vlf,Sox6tm2.1Vlf/Sox6tm2.1Vlf,Tg(Prrx1-cre)1Cjt/? Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL
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MP:0000552 | abnormal radius morphology | "malformation of the short bone of the lateral forearm" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Sox5tm2Vlf/Sox5tm2Vlf,Sox6tm2.1Vlf/Sox6tm2.1Vlf,Tg(Prrx1-cre)1Cjt/? Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL
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MP:0000558 | abnormal tibia morphology | "atructural anomaly of the medial and larger of the two bones of the lower leg" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Sox5tm2Vlf/Sox5tm2Vlf,Sox6tm2.1Vlf/Sox6tm2.1Vlf,Tg(Prrx1-cre)1Cjt/? Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL
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MP:0000572 | abnormal autopod morphology | "malformation of the hand or foot" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Sox5tm2Vlf/Sox5tm2Vlf,Sox6tm2.1Vlf/Sox6tm2.1Vlf,Tg(Prrx1-cre)1Cjt/? Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL
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MP:0000592 | short tail | "reduced length of tail compared to control " [J:55583] |
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Allelic Composition: Cdkn2atm1Rdp/Cdkn2atm1Rdp,Tg(Mt1-HGFSF)19Lmb/0 Genetic Background: involves: 129/Sv * C57BL/6J * FVB/N * SJL
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MP:0001258 | decreased body length | "decreased crown to tail distance compared to controls" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator] |
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Allelic Composition: Cdkn2atm1Rdp/Cdkn2atm1Rdp,Tg(Mt1-HGFSF)19Lmb/0 Genetic Background: involves: 129/Sv * C57BL/6J * FVB/N * SJL
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MP:0001265 | reduced body size | "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170] |
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Allelic Composition: Sox5tm1Vlf/Sox5+,Sox6tm1Vlf/Sox6+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Sox5tm2Vlf/Sox5tm2Vlf,Sox6tm2.1Vlf/Sox6tm2.1Vlf,Tg(Prrx1-cre)1Cjt/? Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL
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MP:0001270 | distended abdomen | "abdomen appears curved outward or swollen; can be due to skeletal axial defects, enlarged visceral organs or megacolon" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Cdkn2atm1Rdp/Cdkn2atm1Rdp,Tg(Mt1-HGFSF)19Lmb/0 Genetic Background: involves: 129/Sv * C57BL/6J * FVB/N * SJL
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MP:0001575 | cyanosis | "a dark bluish or purple skin discoloration resulting from deficient oxygenation of the blood" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60159] |
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Allelic Composition: Mdm2tm1.1Ypz/Mdm2+,Tg(IghMyc)22Bri/0 Genetic Background: B6.Cg-Mdm2tm1.1Ypz Tg(IghMyc)22Bri
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MP:0001785 | edema | "an accumulation of an excessive amount of watery fluid in cells or intercellular tissues" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54065] |
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Allelic Composition: Cdkn2atm1Rdp/Cdkn2atm1Rdp,Tg(Mt1-HGFSF)19Lmb/0 Genetic Background: involves: 129/Sv * C57BL/6J * FVB/N * SJL
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MP:0001953 | respiratory failure | "cessation of or failure to commence breathing" [MGI:cls, J:60159] |
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Allelic Composition: Cdkn2atm1Rdp/Cdkn2atm1Rdp,Tg(Mt1-HGFSF)19Lmb/0 Genetic Background: involves: 129/Sv * C57BL/6J * FVB/N * SJL
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MP:0001954 | respiratory distress | "physical difficulty or inability to breathe" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931] |
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Allelic Composition: Cdkn2atm1Rdp/Cdkn2atm1Rdp,Tg(Mt1-HGFSF)19Lmb/0 Genetic Background: involves: 129/Sv * C57BL/6J * FVB/N * SJL
Allelic Composition: Sox5Tn(sb-lacZ,GFP)IF2.1Jtak/Sox5Tn(sb-lacZ,GFP)IF2.1Jtak Genetic Background: involves: C3H * C57BL/6 * DBA/2 * ICR
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MP:0002109 | abnormal limb morphology | "abnormal development of limbs resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Sox5tm2Vlf/Sox5tm2Vlf,Tg(Prrx1-cre)1Cjt/? Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL
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MP:0002128 | abnormal blood circulation | "failure or atypical movement in the flow of blood from the heart to the vasculature and back to the heart" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Cdkn2atm1Rdp/Cdkn2atm1Rdp,Tg(Mt1-HGFSF)19Lmb/0 Genetic Background: involves: 129/Sv * C57BL/6J * FVB/N * SJL
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MP:0002169 | no phenotype detected | "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Sox5tm2.1Vlf/Sox5tm2.1Vlf Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6J * SJL
Allelic Composition: Sox5tm2Vlf/Sox5tm2Vlf,Tg(Prrx1-cre)1Cjt/? Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL
Allelic Composition: Sox5tm1.1Tlu/Sox5tm1.1Tlu Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ * FVB/N) or (involves: 129S1/Sv * 129X1/SvJ * CD-1 * FVB/N)
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MP:0002187 | abnormal fibula morphology | "malformation of the lateral and smaller bone of the lower limb" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Sox5tm2Vlf/Sox5tm2Vlf,Sox6tm2.1Vlf/Sox6tm2.1Vlf,Tg(Prrx1-cre)1Cjt/? Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL
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MP:0002657 | chondrodystrophy | "abnormal development of the cartilage primordia of long bones, resulting in abnormally short extremities but normal head and trunk" [il:Ira Lu , Mouse Genome Informatics Curator] |
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Allelic Composition: Cdkn2atm1Rdp/Cdkn2atm1Rdp,Tg(Mt1-HGFSF)19Lmb/0 Genetic Background: involves: 129/Sv * C57BL/6J * FVB/N * SJL
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MP:0002896 | abnormal bone mineralization | "defect in the process by which minerals are deposited into bone" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Cdkn2atm1Rdp/Cdkn2atm1Rdp,Tg(Mt1-HGFSF)19Lmb/0 Genetic Background: involves: 129/Sv * C57BL/6J * FVB/N * SJL
Allelic Composition: Sox5tm1Vlf/Sox5+,Sox6tm1Vlf/Sox6+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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MP:0002898 | absent cartilage | "absence of the nonvascular, resilient, flexible connective tissue found primarily in joints, walls of the thorax, and tubular structures, but which also comprises most of the skeleton in early fetal life " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Cdkn2atm1Rdp/Cdkn2atm1Rdp,Tg(Mt1-HGFSF)19Lmb/0 Genetic Background: involves: 129/Sv * C57BL/6J * FVB/N * SJL
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MP:0003048 | abnormal cervical vertebrae morphology | "malformation of any or all of the seven bony segments of the spine located anterior to the thoracic vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator] |
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Allelic Composition: Faslpr/Faslpr Genetic Background: MRL.Cg-Tnfrsf9tm1Byk Faslpr
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MP:0004321 | short sternum | "reduced length of the long flat bone of the chest which articulates with clavicle and first seven rib pairs" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Cdkn2atm1Rdp/Cdkn2atm1Rdp,Tg(Mt1-HGFSF)19Lmb/0 Genetic Background: involves: 129/Sv * C57BL/6J * FVB/N * SJL
Allelic Composition: Sox5tm1Vlf/Sox5+,Sox6tm1Vlf/Sox6+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Sox5tm2Vlf/Sox5tm2Vlf,Sox6tm2.1Vlf/Sox6tm2.1Vlf,Tg(Prrx1-cre)1Cjt/? Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL
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MP:0004624 | abnormal thoracic cage | "any structural anomaly of the bony and cartilaginous structure enclosing the thoracic cavity, consisting of the thoracic vertebrae, ribs, costal cartilages, and sternum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Cdkn2atm1Rdp/Cdkn2atm1Rdp,Tg(Mt1-HGFSF)19Lmb/0 Genetic Background: involves: 129/Sv * C57BL/6J * FVB/N * SJL
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MP:0004672 | short ribs | "reduced length of the bones forming the bony wall of the chest" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Cdkn2atm1Rdp/Cdkn2atm1Rdp,Tg(Mt1-HGFSF)19Lmb/0 Genetic Background: involves: 129/Sv * C57BL/6J * FVB/N * SJL
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MP:0004704 | short vertebral column | "decreased rostral-caudal length of the complete structure forming the rostral-caudal axis of the skeleton formed from the alternating segments of vertebra and intervertebral discs which support the spinal cord" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Cdkn2atm1Rdp/Cdkn2atm1Rdp,Tg(Mt1-HGFSF)19Lmb/0 Genetic Background: involves: 129/Sv * C57BL/6J * FVB/N * SJL
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MP:0005108 | abnormal ulna morphology | "malformation of the medial and larger of the two bones of the forearm" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:83132] |
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Allelic Composition: Sox5tm2Vlf/Sox5tm2Vlf,Sox6tm2.1Vlf/Sox6tm2.1Vlf,Tg(Prrx1-cre)1Cjt/? Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL
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MP:0008277 | abnormal sternum ossification | "anomaly in the process of the formation of the sternum bone by the replacement of cartilage tissue with mineralized bone" [GO:0001958, MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"] |
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Allelic Composition: Faslpr/Faslpr Genetic Background: MRL.Cg-Tnfrsf9tm1Byk Faslpr
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MP:0009886 | failure of palatal shelf elevation | "the palatal shelves fail to move from a vertical position in the orofacial cavity to a horizontal apposition above the developing tongue" [PMID:16680722] |
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Allelic Composition: Cdkn2atm1Rdp/Cdkn2atm1Rdp,Tg(Mt1-HGFSF)19Lmb/0 Genetic Background: involves: 129/Sv * C57BL/6J * FVB/N * SJL
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MP:0009888 | palatal shelves fail to meet at midline | "polarized growth towards the midline following palatal shelf elevation does not occur" [PMID:16942766] |
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Allelic Composition: Faslpr/Faslpr Genetic Background: MRL.Cg-Tnfrsf9tm1Byk Faslpr
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MP:0009890 | cleft secondary palate | "congenital fissure of the tissues normally uniting to form the secondary palate" [PMID:16680722] |
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Allelic Composition: Cdkn2atm1Rdp/Cdkn2atm1Rdp,Tg(Mt1-HGFSF)19Lmb/0 Genetic Background: involves: 129/Sv * C57BL/6J * FVB/N * SJL
Allelic Composition: Sox5tm2.1Vlf/Sox5tm2.1Vlf Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6J * SJL
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MP:0010099 | abnormal thoracic cage shape | "anomaly in the overall regular dome shape of the ribcage" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Cdkn2atm1Rdp/Cdkn2atm1Rdp,Tg(Mt1-HGFSF)19Lmb/0 Genetic Background: involves: 129/Sv * C57BL/6J * FVB/N * SJL
Allelic Composition: Sox5tm2.1Vlf/Sox5tm2.1Vlf Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6J * SJL
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MP:0011087 | complete neonatal lethality | "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith] |
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Allelic Composition: Cdkn2atm1Rdp/Cdkn2atm1Rdp,Tg(Mt1-HGFSF)19Lmb/0 Genetic Background: involves: 129/Sv * C57BL/6J * FVB/N * SJL
Allelic Composition: Sox5tm2.1Vlf/Sox5tm2.1Vlf Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6J * SJL
Allelic Composition: Sox5Tn(sb-lacZ,GFP)IF2.1Jtak/Sox5Tn(sb-lacZ,GFP)IF2.1Jtak Genetic Background: involves: C3H * C57BL/6 * DBA/2 * ICR
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MP:0011099 | complete lethality throughout fetal growth and development | "death of all organisms of a given genotype in a population between the completion of organogenesis and birth (Mus: E14 to approximately E18.5)" [MGI:csmith] |
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Allelic Composition: Cdkn2atm1Rdp/Cdkn2atm1Rdp,Tg(Mt1-HGFSF)19Lmb/0 Genetic Background: involves: 129/Sv * C57BL/6J * FVB/N * SJL
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MP:0012514 | pectus excavatum | "a caved-in or sunken appearance of the anterior chest wall; the congenital deformity can either be present at birth or may not be visible until puberty" [MGI:anna] |
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Allelic Composition: Cdkn2atm1Rdp/Cdkn2atm1Rdp,Tg(Mt1-HGFSF)19Lmb/0 Genetic Background: involves: 129/Sv * C57BL/6J * FVB/N * SJL
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