MP:0000111 | cleft palate | "congenital fissure of the tissues normally uniting to form the palate" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840] |
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Allelic Composition: Foxa2tm1.1(rtTa)Moon/Foxa2tm1.1(rtTa)Moon,Gt(ROSA)26Sortm1Sor/?,Tg(tetO-cre)1Jaw/? Genetic Background: involves: C57BL/6 * SJL
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MP:0000440 | domed skull | |
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Allelic Composition: Opa1Q285X/Opa1Q285X Genetic Background: involves: C3HeB/FeJ * C57BL/6JCrl
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MP:0000496 | abnormal small intestine morphology | "structural or developmental anomalies of the intestinum tenue " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Opa1Q285X/Opa1Q285X Genetic Background: involves: C3HeB/FeJ * C57BL/6JCrl
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MP:0000527 | abnormal kidney development | "anomalous differentiation of the paired organs responsible for urine secretion" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Hesx1tm1Icar/Hesx1tm1Icar Genetic Background: involves: 129P2/OlaHsd
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MP:0000628 | abnormal mammary gland development | "aberration in the differentiation of the mammary gland during early embryogenesis or during sexual maturity" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Akt2tm1.1Mbb/Akt2+,Lepob/Lepob Genetic Background: B6.Cg-Lepob Akt2tm1.1Mbb
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MP:0000662 | abnormal branching of the mammary ductal tree | "anomaly in the development of the channels that secrete milk and direct milk to the nipple" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Akt2tm1.1Mbb/Akt2+,Lepob/Lepob Genetic Background: B6.Cg-Lepob Akt2tm1.1Mbb
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MP:0000914 | exencephaly | "neurocranial defects resulting in exposure or extrusion of the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840] |
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Allelic Composition: Pygo2tm1.2Xdai/Pygo2tm1.2Xdai Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Pygo2tm1.2Ssp/Pygo2tm1.2Ssp,Tg(CMV-cre)1Cgn/? Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * Black Swiss
Allelic Composition: Pygo1tm1.1Ssp/Pygo1tm1.1Ssp,Pygo2tm1.2Ssp/Pygo2tm1.2Ssp Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * Black Swiss
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MP:0001176 | abnormal lung development | "malformation or arrest of differentiation of the organs of respiration" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931] |
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Allelic Composition: Opa1Q285X/Opa1Q285X Genetic Background: involves: C3HeB/FeJ * C57BL/6JCrl
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MP:0001288 | abnormal lens induction | "malformation of or failure to form the transparent, biconvex structure of the eye which is situated behind the iris and in front of the vitreous humor" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Pygo2tm1.1Ssp/Pygo2tm1.1Ssp,Tg(Pax6-cre,GFP)1Pgr/? Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB
Allelic Composition: Pygo2tm1.1Ssp/Pygo2tm1.2Ssp,Tfap2atm1(cre)Moon/? Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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MP:0001290 | delayed eyelid opening | "late average time for the first postnatal eye opening" [J:17792] |
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Allelic Composition: Pygo2tm1.2Xdai/Pygo2tm1.2Xdai Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0001297 | microphthalmia | "reduced average size of the eyes" [J:18048] |
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Allelic Composition: Hesx1tm1Icar/Hesx1tm1Icar Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Pygo2tm1.2Xdai/Pygo2tm1.2Xdai Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0001306 | small lens | "reduced size of the transparent structure of the eye responsible for focusing light rays" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840] |
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Allelic Composition: Hesx1tm1Icar/Hesx1tm1Icar Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Pygo2tm1.1Ssp/Pygo2tm1.1Ssp,Tg(Pax6-cre,GFP)1Pgr/? Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB
Allelic Composition: Pygo2tm1.1Ssp/Pygo2tm1.2Ssp,Tg(Pax6-cre,GFP)1Pgr/? Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB
Allelic Composition: Pygo2tm1.1Ssp/Pygo2tm1.2Ssp,H2afvTg(Wnt1-cre)11Rth/? Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
Allelic Composition: Pygo2tm1.1Ssp/Pygo2tm1.2Ssp,Tg(Pax6-cre,GFP)1Pgr/?,H2afvTg(Wnt1-cre)11Rth/? Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * FVB
Allelic Composition: Pygo2tm1.1Ssp/Pygo2tm1.2Ssp,Tfap2atm1(cre)Moon/? Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Pygo1tm1.1Ssp/Pygo1tm1.1Ssp,Pygo2tm1.2Ssp/Pygo2tm1.2Ssp Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Pygo1tm1.1Ssp/Pygo1+,Pygo2tm1.2Ssp/Pygo2tm1.2Ssp Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Pygo2tm1.2Xdai/Pygo2tm1.2Xdai Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0001312 | abnormal cornea morphology | "malformation or absence of the transparent anterior portion of the fibrous coat of the eye that serves as the chief refractory structure " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Opa1Q285X/Opa1Q285X Genetic Background: involves: C3HeB/FeJ * C57BL/6JCrl
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MP:0001325 | abnormal retina morphology | "structural or developmental anomaly of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Pygo2tm1.2Xdai/Pygo2tm1.2Xdai Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Pygo1tm1.1Ssp/Pygo1tm1.1Ssp,Pygo2tm1.2Ssp/Pygo2tm1.2Ssp Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * Black Swiss
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MP:0001922 | reduced male fertility | "reduced ability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61340] |
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Allelic Composition: Nlrp3tm3.1Hhf/Nlrp3+ Genetic Background: involves: 129
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MP:0001925 | male infertility | "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409] |
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Allelic Composition: Nlrp3tm3.1Hhf/Nlrp3+ Genetic Background: involves: 129
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MP:0002135 | abnormal kidney morphology | "abnormal development of the kidney resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Foxa2tm1.1(rtTa)Moon/Foxa2tm1.1(rtTa)Moon,Gt(ROSA)26Sortm1Sor/?,Tg(tetO-cre)1Jaw/? Genetic Background: involves: C57BL/6 * SJL
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MP:0002687 | oligozoospermia | "reduced concentration of spermatozoa " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:57312] |
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Allelic Composition: Nlrp3tm3.1Hhf/Nlrp3+ Genetic Background: involves: 129
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MP:0002840 | abnormal lens fibers morphology | "structural anomaly of the elongated cells of the crystalline lens of the eye" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Pygo2tm1.2Xdai/Pygo2tm1.2Xdai Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0003078 | aphakia | "absence of the crystalline lens of the eye" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator] |
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Allelic Composition: Hesx1tm1Icar/Hesx1tm1Icar Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Pygo2tm1.1Ssp/Pygo2tm1.1Ssp,Tg(Pax6-cre,GFP)1Pgr/? Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB
Allelic Composition: Pygo2tm1.2Xdai/Pygo2tm1.2Xdai Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Pygo2tm1.2Ssp/Pygo2tm1.2Ssp,Tg(CMV-cre)1Cgn/? Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * Black Swiss
Allelic Composition: Pygo1tm1.1Ssp/Pygo1tm1.1Ssp,Pygo2tm1.2Ssp/Pygo2tm1.2Ssp Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * Black Swiss
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MP:0003237 | abnormal lens epithelium morphology | "malformation in the one or more of the layers of epithelial cells in the lens" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:93301] |
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Allelic Composition: Pygo2tm1.1Ssp/Pygo2tm1.1Ssp,Tg(Pax6-cre,GFP)1Pgr/? Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB
Allelic Composition: Pygo2tm1.2Xdai/Pygo2tm1.2Xdai Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0003672 | abnormal ureter development | "anomalous differentiation of the tube that conducts the urine from the renal pelvis to the bladder" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:96485] |
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Allelic Composition: Pygo2tm1.2Ssp/Pygo2tm1.2Ssp,Tg(CMV-cre)1Cgn/? Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * Black Swiss
Allelic Composition: Pygo1tm1.1Ssp/Pygo1tm1.1Ssp,Pygo2tm1.2Ssp/Pygo2tm1.2Ssp Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * Black Swiss
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MP:0003704 | abnormal hair follicle development | "anomalous development of the epidermis from which the hair shaft develops " [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: Pygo2tm1.2Xdai/Pygo2tm1.2Xdai Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0004135 | abnormal mammary gland embryonic development | "aberration in the differentiation of the mammary gland during early embryogenesis" [smb:Susan M Bello, Mouse Genome Informatics Curator, llw2:Linda Washburn , Mouse Genome Informatics Curator] |
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Allelic Composition: Akt2tm1.1Mbb/Akt2+,Lepob/Lepob Genetic Background: B6.Cg-Lepob Akt2tm1.1Mbb
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MP:0004200 | reduced fetal size | "smaller proportions of a fetus compared to littermates (sensu Mus: from E14 through birth)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hesx1tm1Icar/Hesx1tm1Icar Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Pygo2tm1.2Ssp/Pygo2tm1.2Ssp,Tg(CMV-cre)1Cgn/? Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * Black Swiss
Allelic Composition: Pygo1tm1.1Ssp/Pygo1tm1.1Ssp,Pygo2tm1.2Ssp/Pygo2tm1.2Ssp Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * Black Swiss
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MP:0004201 | fetal growth retardation | "slow or limited development during the fetal period (sensu Mus: from E14 through birth)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Pygo2tm1.2Ssp/Pygo2tm1.2Ssp,Tg(CMV-cre)1Cgn/? Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * Black Swiss
Allelic Composition: Pygo1tm1.1Ssp/Pygo1tm1.1Ssp,Pygo2tm1.2Ssp/Pygo2tm1.2Ssp Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * Black Swiss
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MP:0004269 | abnormal optic cup morphology | "any structural anomaly of double walled stuctured formed by expansion and invagination of the distal end of the optic vesicle that develops into the pigmented and sensory layers of the retina while the mouth of the optic cup eventually forms the pupil of the eye" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hesx1tm1Icar/Hesx1tm1Icar Genetic Background: involves: 129P2/OlaHsd
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MP:0005238 | increased brain size | "larger than the normal physical proportions of the brain" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:57958] |
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Allelic Composition: Pygo2tm1.2Xdai/Pygo2tm1.2Xdai Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0005545 | abnormal lens development | "aberrant formation of the transparent structure of the eye responsible for focusing light rays" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Pygo2tm1.2Xdai/Pygo2tm1.2Xdai Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0006269 | abnormal mammary gland growth during pregnancy | "anomaly in the extensive and rapid branching of the mammary ducts, expansion of mammary epithelium in the stroma between the ducts with or without abnormalities in nipple maturation " [llw2:Linda Washburn , Mouse Genome Informatics Curator] |
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Allelic Composition: Akt2tm1.1Mbb/Akt2+,Lepob/Lepob Genetic Background: B6.Cg-Lepob Akt2tm1.1Mbb
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MP:0006270 | abnormal mammary gland growth during lactation | "anomaly in the final stage of mammary growth that occurs during the start of lactation" [llw2:Linda Washburn , Mouse Genome Informatics Curator] |
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Allelic Composition: Akt2tm1.1Mbb/Akt2+,Lepob/Lepob Genetic Background: B6.Cg-Lepob Akt2tm1.1Mbb
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MP:0006380 | abnormal spermatid morphology | "anomaly in the number or structure of the male germ cells that without further cell division give rise to mature spermatozoa" [ISBN:0-8036-0655-99 "Taber s Cyclopedic Medical Dictionary, 19th edition", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Nlrp3tm3.1Hhf/Nlrp3+ Genetic Background: involves: 129
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MP:0009674 | decreased birth weight | "reduction in average weight at birth compared to controls" [RGD:cur "Rat Genome Database submission"] |
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Allelic Composition: Pygo2tm1.2Xdai/Pygo2tm1.2Xdai Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0009703 | decreased birth body size | "reduction in average body size at birth compared to controls" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Pygo2tm1.2Xdai/Pygo2tm1.2Xdai Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0010174 | decreased mammary gland epithelium proliferation | "decrease in the expansion rate of the cells of the mammary gland epithelium by cell division" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Akt2tm1.1Mbb/Akt2+,Lepob/Lepob Genetic Background: B6.Cg-Lepob Akt2tm1.1Mbb
Allelic Composition: Pygo2tm1.2Xdai/Pygo2tm1.2Xdai Genetic Background: involves: 129P2/OlaHsd
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MP:0010249 | lactation failure | "mammary glands do not secrete milk after parturition" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Akt2tm1.1Mbb/Akt2+,Lepob/Lepob Genetic Background: B6.Cg-Lepob Akt2tm1.1Mbb
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MP:0011087 | complete neonatal lethality | "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith] |
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Allelic Composition: Pygo2tm1.2Ssp/Pygo2tm1.2Ssp,Tg(CMV-cre)1Cgn/? Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * Black Swiss
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MP:0011088 | partial neonatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the neonatal period after birth (Mus: P0)" [MGI:csmith] |
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Allelic Composition: Hesx1tm1Icar/Hesx1tm1Icar Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Pygo1tm1.1Ssp/Pygo1tm1.1Ssp,Pygo2tm1.2Ssp/Pygo2tm1.2Ssp Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * Black Swiss
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MP:0011089 | complete perinatal lethality | "death of all organisms of a given genotype in a population within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith] |
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Allelic Composition: Pygo2tm1.2Xdai/Pygo2tm1.2Xdai Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0012168 | abnormal optic placode morphology | "any structural anomaly of the paired thickenings of surface ectoderm that become invaginated to form the embryonic lens vesicles" [MGI:anna] |
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Allelic Composition: Pygo2tm1.1Ssp/Pygo2tm1.1Ssp,Tg(Pax6-cre,GFP)1Pgr/? Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB
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MP:0030242 | small optic pit | "reduced size of either or both of the two pits that appear bilaterally in the region destined to become the forebrain as the cranial neural folds fuse; these optic pits or sulci continue to deepen laterally and bulge from the two sides of the forebrain to become the optic vesicles" [MGI:anna] |
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Allelic Composition: Pygo2tm1.1Ssp/Pygo2tm1.1Ssp,Tg(Pax6-cre,GFP)1Pgr/? Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB
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