ENSGALG00000017414


Gallus gallus

Features
Gene ID: ENSGALG00000017414
  
Biological name :JUP
  
Synonyms : junction plakoglobin / JUP
  
Possible biological names infered from orthology : P14923 / Q02257
  
Species: Gallus gallus
  
Chr. number: 27
Strand: -1
Band:
Gene start: 5081253
Gene end: 5096768
  
Corresponding Affymetrix probe sets: Gga.8747.1.S1_at (Chicken Array)   GgaAffx.2298.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000028049
Ensembl peptide - ENSGALP00000058698
Ensembl peptide - ENSGALP00000052117
Ensembl peptide - ENSGALP00000049651
NCBI entrez gene - 429710     See in Manteia.
RefSeq - NM_001267553
RefSeq Peptide - NP_001254482
swissprot - E1C1V3
swissprot - A0A1L1RIX5
swissprot - A0A1D5PH40
swissprot - A0A1D5PA91
Ensembl - ENSGALG00000017414
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 jupaENSDARG00000070787Danio rerio
 jupbENSDARG00000059067Danio rerio
 JUPENSG00000173801Homo sapiens
 JupENSMUSG00000001552Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CTNNB1 / catenin beta-1 / P35222* / Q02248*ENSGALG0000003720362


Protein motifs (from Interpro)
Interpro ID Name
 IPR000225  Armadillo
 IPR011989  Armadillo-like helical
 IPR013284  Beta-catenin
 IPR016024  Armadillo-type fold
 IPR030461  Junction plakoglobin/protein humpback-2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001954 positive regulation of cell-matrix adhesion IEA
 biological_processGO:0002159 desmosome assembly IEA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0016477 cell migration IEA
 biological_processGO:0034333 adherens junction assembly IEA
 biological_processGO:0042127 regulation of cell proliferation IEA
 biological_processGO:0042307 positive regulation of protein import into nucleus IEA
 biological_processGO:0043537 negative regulation of blood vessel endothelial cell migration IEA
 biological_processGO:0043588 skin development IEA
 biological_processGO:0045766 positive regulation of angiogenesis IEA
 biological_processGO:0050982 detection of mechanical stimulus IEA
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity IEA
 biological_processGO:0071681 cellular response to indole-3-methanol IEA
 biological_processGO:0072659 protein localization to plasma membrane IEA
 biological_processGO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication IEA
 biological_processGO:0086091 regulation of heart rate by cardiac conduction IEA
 biological_processGO:0098609 cell-cell adhesion IEA
 biological_processGO:0098911 regulation of ventricular cardiac muscle cell action potential IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005882 intermediate filament IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005911 cell-cell junction IEA
 cellular_componentGO:0005913 cell-cell adherens junction IEA
 cellular_componentGO:0014704 intercalated disc IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016342 catenin complex IEA
 cellular_componentGO:0030018 Z disc IEA
 cellular_componentGO:0030057 desmosome IEA
 cellular_componentGO:0032993 protein-DNA complex IEA
 cellular_componentGO:0071665 gamma-catenin-TCF7L2 complex IEA
 molecular_functionGO:0003713 transcription coactivator activity IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0005198 structural molecule activity IEA
 molecular_functionGO:0019903 protein phosphatase binding IEA
 molecular_functionGO:0045294 alpha-catenin binding IEA
 molecular_functionGO:0045296 cadherin binding IEA
 molecular_functionGO:0050839 cell adhesion molecule binding IEA


Pathways (from Reactome)
Pathway description
Adherens junctions interactions
VEGFR2 mediated vascular permeability
Neutrophil degranulation
Keratinization
Formation of the cornified envelope


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000000681 PAK1 / p21 (RAC1) activated kinase 1 / Q13153* / Mus musculus p21 protein (Cdc42/Rac)-activated kinase 1 (Pak1), transcript variant 3, mRNA.*  / reaction
 ENSGALG00000008058 PAK3 / p21 (RAC1) activated kinase 3 / O75914* / Q61036* / Serine/threonine-protein kinase PAK 3 *  / reaction
 ENSGALG00000006426 PAK2 / p21 (RAC1) activated kinase 2 / Q13177* / Q8CIN4* / Serine/threonine-protein kinase PAK 2 PAK-2p27 PAK-2p34*  / reaction
 ENSGALG00000002447 CTNNA1 / catenin alpha 1 / P26231* / P35221*  / complex / reaction
 ENSGALG00000032349 CDH5 / Q8AYD0 / Cadherin-5 / P33151* / P55284*  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr