ENSGALG00000032349


Gallus gallus

Features
Gene ID: ENSGALG00000032349
  
Biological name :CDH5
  
Synonyms : Cadherin-5 / CDH5 / Q8AYD0
  
Possible biological names infered from orthology : P33151 / P55284
  
Species: Gallus gallus
  
Chr. number: 11
Strand: -1
Band:
Gene start: 11674123
Gene end: 11703375
  
Corresponding Affymetrix probe sets: Gga.5171.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000043893
NCBI entrez gene - 374068     See in Manteia.
RefSeq - NM_204227
RefSeq - XM_015292499
RefSeq Peptide - NP_989558
swissprot - Q8AYD0
Ensembl - ENSGALG00000032349
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cdh5ENSDARG00000075549Danio rerio
 CDH5ENSG00000179776Homo sapiens
 Cdh5ENSMUSG00000031871Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000233  Cadherin, cytoplasmic domain
 IPR002126  Cadherin
 IPR015919  Cadherin-like
 IPR020894  Cadherin conserved site
 IPR027397  Catenin binding domain superfamily
 IPR030052  VE-cadherin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001955 blood vessel maturation IEA
 biological_processGO:0007043 cell-cell junction assembly IEA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules IEA
 biological_processGO:0007179 transforming growth factor beta receptor signaling pathway IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0045766 positive regulation of angiogenesis IEA
 biological_processGO:0050728 negative regulation of inflammatory response IEA
 biological_processGO:0060317 cardiac epithelial to mesenchymal transition IMP
 biological_processGO:0098609 cell-cell adhesion IEA
 biological_processGO:1903142 positive regulation of establishment of endothelial barrier IEA
 biological_processGO:2000114 regulation of establishment of cell polarity IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005911 cell-cell junction IEA
 cellular_componentGO:0005912 adherens junction IEA
 cellular_componentGO:0005913 cell-cell adherens junction IEA
 cellular_componentGO:0005923 bicellular tight junction IEA
 cellular_componentGO:0009897 external side of plasma membrane IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0071944 cell periphery IEA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0008013 beta-catenin binding IEA
 molecular_functionGO:0019903 protein phosphatase binding IEA
 molecular_functionGO:0044325 ion channel binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Adherens junctions interactions
VEGFR2 mediated vascular permeability


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000000681 PAK1 / p21 (RAC1) activated kinase 1 / Q13153* / Mus musculus p21 protein (Cdc42/Rac)-activated kinase 1 (Pak1), transcript variant 3, mRNA.*  / reaction
 ENSGALG00000008058 PAK3 / p21 (RAC1) activated kinase 3 / O75914* / Q61036* / Serine/threonine-protein kinase PAK 3 *  / reaction
 ENSGALG00000006426 PAK2 / p21 (RAC1) activated kinase 2 / Q13177* / Q8CIN4* / Serine/threonine-protein kinase PAK 2 PAK-2p27 PAK-2p34*  / reaction
 ENSGALG00000017414 JUP / junction plakoglobin / P14923* / Q02257*  / complex
 ENSGALG00000002447 CTNNA1 / catenin alpha 1 / P26231* / P35221*  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr