ENSGALG00000038141


Gallus gallus

Features
Gene ID: ENSGALG00000038141
  
Biological name :NCF4
  
Synonyms : NCF4 / neutrophil cytosol factor 4
  
Possible biological names infered from orthology : neutrophil cytosolic factor 4 / P97369 / Q15080
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 51610637
Gene end: 51620775
  
Corresponding Affymetrix probe sets: GgaAffx.12658.1.S1_at (Chicken Array)   GgaAffx.7943.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000044384
NCBI entrez gene - 418052     See in Manteia.
RefSeq - XM_015285360
RefSeq - NM_001039272
RefSeq - XM_015285353
RefSeq - XM_015285356
RefSeq - XM_015285351
RefSeq Peptide - NP_001034361
swissprot - A0A1D5NVK9
Ensembl - ENSGALG00000038141
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ncf4ENSDARG00000040812Danio rerio
 NCF4ENSG00000100365Homo sapiens
 Ncf4ENSMUSG00000071715Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000270  PB1 domain
 IPR000919  Neutrophil cytosol factor P40
 IPR001452  SH3 domain
 IPR001683  Phox homologous domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006909 phagocytosis IEA
 biological_processGO:0043085 positive regulation of catalytic activity IEA
 biological_processGO:0045730 respiratory burst IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0010008 endosome membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0043020 NADPH oxidase complex IEA
 molecular_functionGO:0016176 superoxide-generating NADPH oxidase activator activity IEA
 molecular_functionGO:0032266 phosphatidylinositol-3-phosphate binding IEA
 molecular_functionGO:0035091 phosphatidylinositol binding IEA


Pathways (from Reactome)
Pathway description
ROS, RNS production in phagocytes
Cross-presentation of particulate exogenous antigens (phagosomes)
Detoxification of Reactive Oxygen Species
VEGFA-VEGFR2 Pathway
RHO GTPases Activate NADPH Oxidases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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