ENSGALG00000038924


Gallus gallus

Features
Gene ID: ENSGALG00000038924
  
Biological name :IDE
  
Synonyms : IDE / insulin degrading enzyme
  
Possible biological names infered from orthology : P14735
  
Species: Gallus gallus
  
Chr. number: 6
Strand: 1
Band:
Gene start: 20741800
Gene end: 20794790
  
Corresponding Affymetrix probe sets: GgaAffx.8525.1.S1_at (Chicken Array)   GgaAffx.8525.3.S1_at (Chicken Array)   GgaAffx.8525.3.S1_s_at (Chicken Array)   GgaAffx.8525.6.S1_at (Chicken Array)   GgaAffx.8525.8.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000047668
NCBI entrez gene - 423814     See in Manteia.
RefSeq - XM_004942159
RefSeq - XM_015288833
RefSeq - XM_015288834
RefSeq - XM_015288835
RefSeq - XM_421686
RefSeq - XM_004942157
swissprot - A0A1D5P4Q6
Ensembl - ENSGALG00000038924
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ideENSDARG00000075570Danio rerio
 IDEENSG00000119912Homo sapiens
 IdeENSMUSG00000056999Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NRDC / nardilysin / Nrd1* / O43847* / Q8BHG1* / nardilysin convertase* / Mus musculus nardilysin, N-arginine dibasic convertase, NRD convertase 1 (Nrd1), transcript variant 3, mRNA.*ENSGALG0000001056532


Protein motifs (from Interpro)
Interpro ID Name
 IPR001431  Peptidase M16, zinc-binding site
 IPR007863  Peptidase M16, C-terminal
 IPR011249  Metalloenzyme, LuxS/M16 peptidase-like
 IPR011765  Peptidase M16, N-terminal
 IPR032632  Peptidase M16, middle/third domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0008340 determination of adult lifespan IEA
 biological_processGO:0010815 bradykinin catabolic process IEA
 biological_processGO:0010992 ubiquitin recycling IEA
 biological_processGO:0032461 positive regulation of protein oligomerization IEA
 biological_processGO:0050435 amyloid-beta metabolic process IEA
 biological_processGO:0051260 protein homooligomerization IEA
 biological_processGO:0051603 proteolysis involved in cellular protein catabolic process IEA
 biological_processGO:1901142 insulin metabolic process IEA
 biological_processGO:1901143 insulin catabolic process IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005777 peroxisome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0009986 cell surface IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004222 metalloendopeptidase activity IEA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0042277 peptide binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0043559 insulin binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0140036 ubiquitin-dependent protein binding IEA


Pathways (from Reactome)
Pathway description
Ub-specific processing proteases
Peroxisomal protein import


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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