ENSGALG00000039436


Gallus gallus

Features
Gene ID: ENSGALG00000039436
  
Biological name :DLX2
  
Synonyms : distal-less homeobox 2 / DLX2
  
Possible biological names infered from orthology : Homeobox protein DLX-2 / P40764 / Q07687
  
Species: Gallus gallus
  
Chr. number: 7
Strand: 1
Band:
Gene start: 17917670
Gene end: 17918619
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSGALP00000052409
NCBI entrez gene - 107053847     See in Manteia.
RefSeq - XM_015289773
swissprot - A0A1D5PHX8
Ensembl - ENSGALG00000039436
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dlx2aENSDARG00000079964Danio rerio
 DLX2ENSG00000115844Homo sapiens
 Dlx2ENSMUSG00000023391Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DLX5 / P50577 / Homeobox protein DLX-5 / P56178* / P70396* / distal-less homeobox 5*ENSGALG0000000912950
DLX3 / Gallus gallus distal-less homeobox 3 (DLX3), mRNA. / O60479* / Q64205* / distal-less homeobox 3* / Homeobox protein DLX-3 *ENSGALG0000004052948
DLX1 / homeobox protein DLX-1 / P56177* / Q64317* / distal-less homeobox 1*ENSGALG0000001843936
DLX6 / homeobox protein DLX-6 / P56179* / P70397* / distal-less homeobox 6*ENSGALG0000002319535
DLX4 / distal-less homeobox 4 / P70436* / Q92988* / Homeobox protein DLX-4 *ENSGALG0000004502328
MSX1 / P50223 / Homeobox protein GHOX-7 / P13297* / P28360* / msh homeobox 1* / Homeobox protein MSX-1 *ENSGALG0000001501323
MSX2 / P28362 / Homeobox protein MSX-2 / P35548* / Q03358* / msh homeobox 2*ENSGALG0000003884822


Protein motifs (from Interpro)
Interpro ID Name
 IPR000047  Helix-turn-helix motif
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR020479  Homeobox domain, metazoa
 IPR022135  Distal-less-like homeobox protein, N-terminal domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0009954 proximal/distal pattern formation IEA
 biological_processGO:0021544 subpallium development IEA
 biological_processGO:0021766 hippocampus development IEA
 biological_processGO:0021772 olfactory bulb development IEA
 biological_processGO:0021879 forebrain neuron differentiation IEA
 biological_processGO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment IEA
 biological_processGO:0021892 cerebral cortex GABAergic interneuron differentiation IEA
 biological_processGO:0021893 cerebral cortex GABAergic interneuron fate commitment IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0042475 odontogenesis of dentin-containing tooth IEA
 biological_processGO:0045597 positive regulation of cell differentiation IEA
 biological_processGO:0045746 negative regulation of Notch signaling pathway IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0046533 negative regulation of photoreceptor cell differentiation IEA
 biological_processGO:0048701 embryonic cranial skeleton morphogenesis IEA
 biological_processGO:0048706 embryonic skeletal system development IEA
 biological_processGO:0048715 negative regulation of oligodendrocyte differentiation IEA
 biological_processGO:0048755 branching morphogenesis of a nerve IEA
 biological_processGO:0051216 cartilage development IEA
 biological_processGO:1902871 positive regulation of amacrine cell differentiation IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003727 single-stranded RNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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