ENSGALG00000015013


Gallus gallus

Features
Gene ID: ENSGALG00000015013
  
Biological name :MSX1
  
Synonyms : Homeobox protein GHOX-7 / MSX1 / P50223
  
Possible biological names infered from orthology : Homeobox protein MSX-1 / msh homeobox 1 / P13297 / P28360
  
Species: Gallus gallus
  
Chr. number: 4
Strand: 1
Band:
Gene start: 79398826
Gene end: 79401315
  
Corresponding Affymetrix probe sets: GgaAffx.21776.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000057277
Ensembl peptide - ENSGALP00000024163
NCBI entrez gene - 396484     See in Manteia.
RefSeq - NM_205488
RefSeq Peptide - NP_990819
swissprot - P50223
swissprot - A0A1D5PWE6
Ensembl - ENSGALG00000015013
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 msx1aENSDARG00000116118Danio rerio
 MSX1ENSG00000163132Homo sapiens
 Msx1ENSMUSG00000048450Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MSX2 / P28362 / Homeobox protein MSX-2 / P35548* / Q03358* / msh homeobox 2*ENSGALG0000003884852
DLX5 / P50577 / Homeobox protein DLX-5 / P56178* / P70396* / distal-less homeobox 5*ENSGALG0000000912921
DLX1 / homeobox protein DLX-1 / P56177* / Q64317* / distal-less homeobox 1*ENSGALG0000001843921
DLX2 / distal-less homeobox 2 / P40764* / Q07687* / Homeobox protein DLX-2 *ENSGALG0000003943620
DLX3 / Gallus gallus distal-less homeobox 3 (DLX3), mRNA. / O60479* / Q64205* / distal-less homeobox 3* / Homeobox protein DLX-3 *ENSGALG0000004052918
DLX6 / homeobox protein DLX-6 / P56179* / P70397* / distal-less homeobox 6*ENSGALG0000002319518
DLX4 / distal-less homeobox 4 / P70436* / Q92988* / Homeobox protein DLX-4 *ENSGALG0000004502316


Protein motifs (from Interpro)
Interpro ID Name
 IPR000047  Helix-turn-helix motif
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0000902 cell morphogenesis IEA
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0001837 epithelial to mesenchymal transition IEA
 biological_processGO:0003007 heart morphogenesis IEA
 biological_processGO:0003198 epithelial to mesenchymal transition involved in endocardial cushion formation IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007507 heart development IEA
 biological_processGO:0007517 muscle organ development IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0009952 anterior/posterior pattern specification IEA
 biological_processGO:0010463 mesenchymal cell proliferation IEA
 biological_processGO:0023019 signal transduction involved in regulation of gene expression IEA
 biological_processGO:0030308 negative regulation of cell growth IEA
 biological_processGO:0030326 embryonic limb morphogenesis IEA
 biological_processGO:0030509 BMP signaling pathway IEA
 biological_processGO:0030513 positive regulation of BMP signaling pathway IEA
 biological_processGO:0030900 forebrain development IEA
 biological_processGO:0030901 midbrain development IEA
 biological_processGO:0034504 protein localization to nucleus IEA
 biological_processGO:0035115 embryonic forelimb morphogenesis IEA
 biological_processGO:0035116 embryonic hindlimb morphogenesis IEA
 biological_processGO:0035880 embryonic nail plate morphogenesis IEA
 biological_processGO:0042474 middle ear morphogenesis IEA
 biological_processGO:0042475 odontogenesis of dentin-containing tooth IEA
 biological_processGO:0042476 odontogenesis IEA
 biological_processGO:0042481 regulation of odontogenesis IEA
 biological_processGO:0042733 embryonic digit morphogenesis IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0043392 negative regulation of DNA binding IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048863 stem cell differentiation IEA
 biological_processGO:0050821 protein stabilization IEA
 biological_processGO:0051154 negative regulation of striated muscle cell differentiation IEA
 biological_processGO:0060021 roof of mouth development IEA
 biological_processGO:0060325 face morphogenesis IEA
 biological_processGO:0060349 bone morphogenesis IEA
 biological_processGO:0060536 cartilage morphogenesis IEA
 biological_processGO:0061180 mammary gland epithelium development IEA
 biological_processGO:0061312 BMP signaling pathway involved in heart development IEA
 biological_processGO:0090427 activation of meiosis IEA
 biological_processGO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator IEA
 biological_processGO:2000678 negative regulation of transcription regulatory region DNA binding IEA
 biological_processGO:2001055 positive regulation of mesenchymal cell apoptotic process IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0000982 transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0002039 p53 binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0035326 enhancer binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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