ENSDARG00000116118


Danio rerio

Features
Gene ID: ENSDARG00000116118
  
Biological name :msx1a
  
Synonyms : msx1a / muscle segment homeobox 1a
  
Possible biological names infered from orthology : Homeobox protein MSX-1 / msh homeobox 1 / MSX1 / P13297 / P28360
  
Species: Danio rerio
  
Chr. number: 14
Strand: -1
Band:
Gene start: 10909
Gene end: 12847
  
Corresponding Affymetrix probe sets: Dr.41.1.A1_at (Zebrafish Array)   NM_131273_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000147264
Ensembl peptide - ENSDARP00000145032
NCBI entrez gene - 30527     See in Manteia.
RefSeq - NM_131273
RefSeq Peptide - NP_571348
swissprot - B3DG59
swissprot - Q502Q5
ZFIN ID - ZDB-GENE-980526-312
Ensembl - ENSDARG00000116118
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MSX1ENSGALG00000015013Gallus gallus
 MSX1ENSG00000163132Homo sapiens
 Msx1ENSMUSG00000048450Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
msx2b / Q01704 / muscle segment homeobox 2b / MSX2* / P35548* / msh homeobox 2*ENSDARG0000010102352
msx3 / muscle segment homeobox 3 / P70354* / Mus musculus msh homeobox 3 (Msx3), transcript variant 2, mRNA.*ENSDARG0000001567451
msx2a / muscle segment homeobox 2aENSDARG0000010465150
msx1b / Q03356 / muscle segment homeobox 1b / Msx3* / P70354* / Mus musculus msh homeobox 3 (Msx3), transcript variant 2, mRNA.*ENSDARG0000000888649
dlx4a / Q98879 / distal-less homeobox 4a / DLX4* / P70436* / Q92988* / distal-less homeobox 4* / Homeobox protein DLX-4 *ENSDARG0000001195626
dlx1a / Q98875 / distal-less homeobox 1a / DLX1* / P56177* / distal-less homeobox 1*ENSDARG0000001312525
dlx3b / distal-less homeobox 3b / DLX3* / Q64205* / O60479* / distal-less homeobox 3* / Homeobox protein DLX-3 *ENSDARG0000001462624
dlx2b / Q98876 / distal-less homeobox 2bENSDARG0000001717424
dlx2a / distal-less homeobox 2a / DLX2* / Q07687* / distal-less homeobox 2*ENSDARG0000007996424
dlx6a / Q98877 / distal-less homeobox 6a / DLX6* / P56179* / P70397* / distal-less homeobox 6* / Homeobox protein DLX-6 *ENSDARG0000004229124
dlx4b / Q98878 / distal-less homeobox 4b / DLX4* / P70436* / Q92988* / distal-less homeobox 4* / Homeobox protein DLX-4 *ENSDARG0000007156023
dlx5a / distal-less homeobox 5a / DLX5* / P70396* / P56178* / distal-less homeobox 5* / Homeobox protein DLX-5 *ENSDARG0000004229622


Protein motifs (from Interpro)
Interpro ID Name
 IPR000047  Helix-turn-helix motif
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0043049 otic placode formation IGI
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000051 otic vesicle otic vesicle decreased size , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0000138 otic placode otic placode decreased size , abnormal
otic placode disorganized , abnormal
Show

 ZFA:0000295 trigeminal ganglion trigeminal ganglion decreased size , abnormal
Show

 ZFA:0001114 head head apoptotic , abnormal
Show

 ZFA:0001117 post-vent region post-vent region wholly ventralized , abnormal
post-vent region curved ventral , abnormal
Show

 ZFA:0001458 cranial cartilage cranial cartilage hypoplastic , abnormal
Show

 ZFA:0001460 pharyngeal arch cartilage pharyngeal arch cartilage malformed , abnormal
Show

 ZFA:0001461 chondrocranium cartilage chondrocranium cartilage malformed , abnormal
Show

 ZFA:0001516 ceratobranchial cartilage ceratobranchial cartilage curved , abnormal
ceratobranchial cartilage shortened , abnormal
Show

 ZFA:0009150 Rohon-Beard neuron Rohon-Beard neuron decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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