ENSDARG00000013125


Danio rerio

Features
Gene ID: ENSDARG00000013125
  
Biological name :dlx1a
  
Synonyms : distal-less homeobox 1a / dlx1a / Q98875
  
Possible biological names infered from orthology : distal-less homeobox 1 / DLX1 / Homeobox protein DLX-1 / P56177 / Q64317
  
Species: Danio rerio
  
Chr. number: 9
Strand: 1
Band:
Gene start: 3388099
Gene end: 3390109
  
Corresponding Affymetrix probe sets: Dr.128.1.S1_at (Zebrafish Array)   NM_131305_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000011033
NCBI entrez gene - 30568     See in Manteia.
RefSeq - NM_131305
RefSeq Peptide - NP_571380
swissprot - Q98875
ZFIN ID - ZDB-GENE-990415-48
Ensembl - ENSDARG00000013125
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DLX1ENSGALG00000018439Gallus gallus
 DLX1ENSG00000144355Homo sapiens
 Dlx1ENSMUSG00000041911Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
dlx6a / Q98877 / distal-less homeobox 6a / DLX6* / P56179* / P70397* / distal-less homeobox 6* / Homeobox protein DLX-6 *ENSDARG0000004229158
dlx4b / Q98878 / distal-less homeobox 4b / DLX4* / P70436* / Q92988* / distal-less homeobox 4* / Homeobox protein DLX-4 *ENSDARG0000007156051
dlx4a / Q98879 / distal-less homeobox 4a / DLX4* / P70436* / Q92988* / distal-less homeobox 4* / Homeobox protein DLX-4 *ENSDARG0000001195650
dlx2b / Q98876 / distal-less homeobox 2bENSDARG0000001717438
dlx5a / distal-less homeobox 5a / DLX5* / P70396* / P56178* / distal-less homeobox 5* / Homeobox protein DLX-5 *ENSDARG0000004229637
dlx3b / distal-less homeobox 3b / DLX3* / Q64205* / O60479* / distal-less homeobox 3* / Homeobox protein DLX-3 *ENSDARG0000001462635
dlx2a / distal-less homeobox 2a / DLX2* / Q07687* / distal-less homeobox 2*ENSDARG0000007996434
msx1a / muscle segment homeobox 1a / MSX1* / P28360* / msh homeobox 1*ENSDARG0000011611823
msx2b / Q01704 / muscle segment homeobox 2b / MSX2* / P35548* / msh homeobox 2*ENSDARG0000010102321
msx2a / muscle segment homeobox 2aENSDARG0000010465121
msx1b / Q03356 / muscle segment homeobox 1b / Msx3* / P70354* / Mus musculus msh homeobox 3 (Msx3), transcript variant 2, mRNA.*ENSDARG0000000888621
msx3 / muscle segment homeobox 3 / P70354* / Mus musculus msh homeobox 3 (Msx3), transcript variant 2, mRNA.*ENSDARG0000001567420


Protein motifs (from Interpro)
Interpro ID Name
 IPR000047  Helix-turn-helix motif
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0045597 positive regulation of cell differentiation ISS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISS
 biological_processGO:0046533 negative regulation of photoreceptor cell differentiation ISS
 biological_processGO:0048703 embryonic viscerocranium morphogenesis IGI
 biological_processGO:0051216 cartilage development IGI
 biological_processGO:1902871 positive regulation of amacrine cell differentiation ISS
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000032 hypothalamus hypothalamus morphology , abnormal
Show

 ZFA:0001114 head head apoptotic , abnormal
head decreased size , abnormal
Show

 ZFA:0001205 Meckel s cartilage Meckels cartilage deformed , abnormal
Show

 ZFA:0001399 palatoquadrate cartilage palatoquadrate cartilage deformed , abnormal
palatoquadrate cartilage morphology , abnormal
Show

 ZFA:0001400 ceratohyal cartilage ceratohyal cartilage deformed , abnormal
Show

 ZFA:0001405 ethmoid cartilage ethmoid cartilage decreased size , abnormal
Show

 ZFA:0001422 hyosymplectic cartilage hyosymplectic cartilage deformed , abnormal
hyosymplectic cartilage morphology , abnormal
Show

 ZFA:0001460 pharyngeal arch cartilage pharyngeal arch cartilage decreased size , abnormal
pharyngeal arch cartilage deformed , abnormal
pharyngeal arch cartilage chondrocyte decreased amount , abnormal
Show

 ZFA:0001507 trabecula cranii trabecula cranii decreased size , abnormal
Show

 ZFA:0001511 interhyal cartilage interhyal cartilage aplastic , abnormal
Show

 ZFA:0001516 ceratobranchial cartilage ceratobranchial cartilage deformed , abnormal
ceratobranchial cartilage chondrocyte decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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