ENSDARG00000042296


Danio rerio

Features
Gene ID: ENSDARG00000042296
  
Biological name :dlx5a
  
Synonyms : distal-less homeobox 5a / dlx5a
  
Possible biological names infered from orthology : distal-less homeobox 5 / DLX5 / Homeobox protein DLX-5 / P56178 / P70396
  
Species: Danio rerio
  
Chr. number: 19
Strand: -1
Band:
Gene start: 41470216
Gene end: 41472228
  
Corresponding Affymetrix probe sets: Dr.429.1.S1_at (Zebrafish Array)   NM_131306_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000100492
NCBI entrez gene - 30569     See in Manteia.
RefSeq - NM_131306
RefSeq Peptide - NP_571381
swissprot - Q5XJL9
ZFIN ID - ZDB-GENE-990415-49
Ensembl - ENSDARG00000042296
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DLX5ENSGALG00000009129Gallus gallus
 DLX5ENSG00000105880Homo sapiens
 Dlx5ENSMUSG00000029755Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
dlx3b / distal-less homeobox 3b / DLX3* / Q64205* / O60479* / distal-less homeobox 3* / Homeobox protein DLX-3 *ENSDARG0000001462652
dlx2a / distal-less homeobox 2a / DLX2* / Q07687* / distal-less homeobox 2*ENSDARG0000007996450
dlx2b / Q98876 / distal-less homeobox 2bENSDARG0000001717449
dlx6a / Q98877 / distal-less homeobox 6a / DLX6* / P56179* / P70397* / distal-less homeobox 6* / Homeobox protein DLX-6 *ENSDARG0000004229134
dlx1a / Q98875 / distal-less homeobox 1a / DLX1* / P56177* / distal-less homeobox 1*ENSDARG0000001312533
dlx4a / Q98879 / distal-less homeobox 4a / DLX4* / P70436* / Q92988* / distal-less homeobox 4* / Homeobox protein DLX-4 *ENSDARG0000001195633
dlx4b / Q98878 / distal-less homeobox 4b / DLX4* / P70436* / Q92988* / distal-less homeobox 4* / Homeobox protein DLX-4 *ENSDARG0000007156031
msx2a / muscle segment homeobox 2aENSDARG0000010465120
msx3 / muscle segment homeobox 3 / P70354* / Mus musculus msh homeobox 3 (Msx3), transcript variant 2, mRNA.*ENSDARG0000001567419
msx1b / Q03356 / muscle segment homeobox 1b / Msx3* / P70354* / Mus musculus msh homeobox 3 (Msx3), transcript variant 2, mRNA.*ENSDARG0000000888618
msx1a / muscle segment homeobox 1a / MSX1* / P28360* / msh homeobox 1*ENSDARG0000011611818
msx2b / Q01704 / muscle segment homeobox 2b / MSX2* / P35548* / msh homeobox 2*ENSDARG0000010102318


Protein motifs (from Interpro)
Interpro ID Name
 IPR000047  Helix-turn-helix motif
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR020479  Homeobox domain, metazoa
 IPR022135  Distal-less-like homeobox protein, N-terminal domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000040 median fin fold median fin fold decreased width , abnormal
median fin fold morphology , abnormal
median fin fold posterior region morphology , abnormal
Show

 ZFA:0000089 fin fold actinotrichium fin fold actinotrichium absent , abnormal
Show

 ZFA:0000135 notochord notochord increased size , abnormal
notochord undulate , abnormal
Show

 ZFA:0000141 pectoral fin bud pectoral fin bud absent , abnormal
pectoral fin bud hypoplastic , abnormal
Show

 ZFA:0000184 cleithrum cleithrum absent , abnormal
Show

 ZFA:0000249 cranial nerve I cranial nerve I axon mislocalised , abnormal
Show

 ZFA:0000250 opercle opercle decreased size , abnormal
Show

 ZFA:0000554 olfactory epithelium olfactory epithelium morphology , abnormal
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 ZFA:0000692 symplectic symplectic decreased length , abnormal
Show

 ZFA:0000694 ceratobranchial 5 tooth ceratobranchial 5 tooth decreased size , abnormal
ceratobranchial 5 tooth deformed , abnormal
Show

 ZFA:0000737 cranium cranium bone tissue mislocalised , abnormal
cranium malformed , abnormal
Show

 ZFA:0000912 mesenchyme median fin fold mesenchyme median fin fold disorganized , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased size , abnormal
Show

 ZFA:0001117 post-vent region post-vent region curled , abnormal
Show

 ZFA:0001227 mandibular arch skeleton mandibular arch skeleton joint absent , abnormal
Show

 ZFA:0001269 regenerating fin regenerating fin caudal fin lepidotrichium increased length , abnormal
Show

 ZFA:0001460 pharyngeal arch cartilage pharyngeal arch cartilage hypoplastic , abnormal
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 ZFA:0001521 ceratobranchial 5 cartilage ceratobranchial 5 cartilage absent , abnormal
Show

 ZFA:0001617 otolith otolith fused with otolith , abnormal
Show

 ZFA:0005473 interhyal-epihyal joint interhyal-epihyal joint absent , abnormal
Show

 ZFA:0005661 olfactory bulb glomerulus olfactory bulb glomerulus aplastic/hypoplastic , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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