| MP:0000029 | abnormal malleus morphology | "structural anomaly in the largest of the three auditory ossicles, which resembles a club or hammer " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi,Msx1tm1Bero/Msx1tm1Bero
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
|
| MP:0000031 | abnormal cochlea morphology | "any anomaly, deformity, malformation, impairment or dysfunction of the cochlea" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator, J:21484] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0000034 | abnormal vestibule morphology | "malformed cavity between the semicircular canals and the cochlea of the inner ear" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:1776] |
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Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
|
| MP:0000036 | absent semicircular canals | "missing organ of balance; consists of three bony tubes within which the semicircular ducts are located" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:23837] |
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Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0000039 | abnormal otic capsule morphology | "malformation of the cartilage or bony capsule surrounding the inner ear mechanism" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:23837] |
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Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi,Msx1tm1Bero/Msx1tm1Bero
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
|
| MP:0000041 | absent endolymphatic duct | "missing small membranous canal of the inner ear; connecting membranous labyrinth with the endolymphatic sac" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:1776] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
|
| MP:0000049 | abnormal middle ear morphology | "malformation or malfunction of any components of the tympanic cavity or its ossicles" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
|
| MP:0000060 | delayed bone ossification | "late onset of the formation of bone" [J:40203] |
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Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi,Msx1tm1Bero/Msx1tm1Bero
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
|
| MP:0000074 | abnormal neurocranium morphology | "malformed bones of the skull enclosing the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:55583] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
Allelic Composition: Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: Not Specified
Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi,Msx1tm1Bero/Msx1tm1Bero
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
|
| MP:0000077 | abnormal interparietal bone morphology | "malformed bone of the cranium; lies above and anterior to the occipital bone " [J:61509] |
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Allelic Composition: Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: Not Specified
|
| MP:0000079 | abnormal basioccipital bone morphology | "malformed basilar process of the occipital bone" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:55583] |
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Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi,Msx1tm1Bero/Msx1tm1Bero
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
|
| MP:0000084 | abnormal fontanelle morphology | "structural defect in the membranous interval at the margins of cranial bones in neonates" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:53370] |
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Allelic Composition: Msx1tm1Bero/Msx1tm1Bero
Genetic Background: B6.129P2-Msx1tm1Bero
|
| MP:0000085 | large anterior fontanelle | "enlarged diamond-shaped membranous interval at the junction of the coronal, sagittal and metopic sutures of the cranium" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:53370] |
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Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
|
| MP:0000088 | short mandible | "reduced length of the lower bony framework of the mouth where the inferior teeth are held" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
|
| MP:0000091 | short premaxilla | "reduced length of the anterior and interior portion of the maxilla" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:53370] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
|
| MP:0000094 | absent alveolar process | "missing projecting ridge on the inferior surface of the body of the maxilla containing the tooth sockets" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:17489] |
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Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi,Msx1tm1Bero/Msx1tm1Bero
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
|
| MP:0000097 | short maxilla | "reduced length of the upper jaw bone" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:53370] |
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Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
|
| MP:0000098 | abnormal vomer bone morphology | "missing triangular flat bone of the nasal septum" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
|
| MP:0000102 | abnormal nasal bone morphology | "malformed elongated rectangular bone that forms part of the nasal bridge" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:17489] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
Allelic Composition: Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: Not Specified
|
| MP:0000106 | abnormal basisphenoid bone morphology | "malformed base of the sphenoid bone" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:55583] |
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Allelic Composition: Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: Not Specified
Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi,Msx1tm1Bero/Msx1tm1Bero
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
|
| MP:0000107 | abnormal frontal bone morphology | "malformed bone forming the forehead and part of the eye orbit" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:17489] |
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Allelic Composition: Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: Not Specified
|
| MP:0000109 | abnormal parietal bone morphology | "malformed curved bone forming part of the vault of the cranium" [J:17489] |
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Allelic Composition: Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: Not Specified
|
| MP:0000150 | abnormal rib morphology | "malformed bones forming the bony wall of the chest" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:50311] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
|
| MP:0000350 | abnormal cell proliferation | "anomalous growth and reproduction of similar cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
|
| MP:0000431 | absent palatine shelf | "missing outgrowth of the palatine bone; normally fuses with maxillary shelf to form secondary palate " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:17489] |
Show
Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
|
| MP:0000438 | abnormal skull morphology | "anomalous structure or development of the cranium" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: KitW/KitW
Genetic Background: Not Specified
Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
|
| MP:0000443 | abnormal snout morphology | "anomalous structure or development of the anterior facial part of the muzzle" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Apoetm1Unc/Apoetm1Unc,Tg(APOC1)1Bres/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * CBA/J
|
| MP:0000445 | short snout | "reduced length of the anterior facial part of the muzzle" [J:53370] |
Show
Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
|
| MP:0000452 | abnormal mouth morphology | "anomalous structure or development of the oral cavity" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Apoetm1Unc/Apoetm1Unc,Tg(APOC1)1Bres/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * CBA/J
|
| MP:0000454 | abnormal jaw morphology | "malformation of the bony framework of the mouth where the teeth are held" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Apoetm1Unc/Apoetm1Unc,Tg(APOC1)1Bres/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * CBA/J
|
| MP:0000455 | abnormal maxilla morphology | "malformation of the upper bony framework of the mouth where the superior teeth are held" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: KitW/KitW
Genetic Background: Not Specified
Allelic Composition: Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: Not Specified
|
| MP:0000458 | abnormal mandible morphology | "malformation of the lower bony framework of the mouth where the inferior teeth are held" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: KitW/KitW
Genetic Background: Not Specified
|
| MP:0000556 | abnormal hindlimb morphology | "malformation of the entire posterior extremities" [MGI:tc] |
Show
Allelic Composition: Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: Not Specified
|
| MP:0000564 | syndactyly | "any degree of webbing or fusion of the digits, may involve only soft tissues or also can include bone" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: Not Specified
Allelic Composition: Dlx5tm1Levi/Dlx5/Dlx6tm1Levi,Trp63tm1Aam/Trp63tm1Aam
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Trp63tm1Aam/Trp63tm1Aam,Dlx5tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0000819 | abnormal olfactory bulb morphology | "malformation or absence of the forebrain region that coordinates neuronal signaling involved in the perception of smell; it receives input from the sensory neurons and outputs to the olfactory cortex" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, Principles of Neural Science:ISBN 0-8385-8034-3, J:16461] |
Show
Allelic Composition: Sox1tm1Vep/Sox1tm1Vep,Sox2tm1Vep/Sox2+
Genetic Background: involves: 129S/SvEv
|
| MP:0000913 | abnormal brain development | "malformed or incomplete differentiation of the brain" [MGI:cls, J:49840] |
Show
Allelic Composition: Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: Not Specified
|
| MP:0000914 | exencephaly | "neurocranial defects resulting in exposure or extrusion of the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840] |
Show
Allelic Composition: KitW/KitW
Genetic Background: Not Specified
Allelic Composition: Dlx5tm1Jlr/Dlx5+
Genetic Background: involves: 129X1/SvJ * C57BL/6J
Allelic Composition: Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: Not Specified
Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
|
| MP:0000929 | open neural tube | "incomplete invagination and fusion of the neuroepithelial layer in early development" [MGI:CLS, J:53370, J:62571] |
Show
Allelic Composition: KitW/KitW
Genetic Background: Not Specified
Allelic Composition: Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: Not Specified
|
| MP:0000968 | abnormal sensory neuron innervation | "defective or incomplete supply of nerve fibers to sensory termini or to spinal cord" [J:31622] |
Show
Allelic Composition: Sox1tm1Vep/Sox1tm1Vep,Sox2tm1Vep/Sox2+
Genetic Background: involves: 129S/SvEv
|
| MP:0001093 | small trigeminal ganglion | "reduced size of the trigeminal ganglion" [J:25565, J:17123] |
Show
Allelic Composition: KitW/KitW
Genetic Background: Not Specified
|
| MP:0001265 | reduced body size | "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170] |
Show
Allelic Composition: KitW/KitW
Genetic Background: Not Specified
|
| MP:0001270 | distended abdomen | "abdomen appears curved outward or swollen; can be due to skeletal axial defects, enlarged visceral organs or megacolon" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
|
| MP:0001402 | hypoactivity | "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289] |
Show
Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
|
| MP:0001436 | abnormal suckling behavior | "reduced ability or inability to exert suction by the mouth, or atypical suckling pattern" [J:16461] |
Show
Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
|
| MP:0001890 | anencephaly | "absence of the bones of the cranial vault and absent or rudimentary cerebral and cerebellar hemispheres, brainstem, and basal ganglia" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:31571] |
Show
Allelic Composition: Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: Not Specified
|
| MP:0001954 | respiratory distress | "physical difficulty or inability to breathe" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931] |
Show
Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
|
| MP:0002081 | perinatal lethality | "death anytime between E18.5 and postnatal day 1 " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Apoetm1Unc/Apoetm1Unc,Tg(APOC1)1Bres/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * CBA/J
|
| MP:0002098 | abnormal vibrissae morphology | "irregular or unusual structure, appearance, or alignment of the vibrissae" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Apoetm1Unc/Apoetm1Unc,Tg(APOC1)1Bres/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * CBA/J
|
| MP:0002110 | abnormal digit morphology | "abnormal development of the digits resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Apoetm1Unc/Apoetm1Unc,Tg(APOC1)1Bres/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * CBA/J
|
| MP:0002116 | abnormal craniofacial bone morphology | "abnormal development of cranial or facial bones resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Apoetm1Unc/Apoetm1Unc,Tg(APOC1)1Bres/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * CBA/J
|
| MP:0002169 | no phenotype detected | "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Dmrta1tm1.1Zark/Dmrta1+
Genetic Background: involves: 129S1/Sv * FVB/N
Allelic Composition: Dlx5tm1(cre/ERT2)Zjh/Dlx5+
Genetic Background: C57BL/6-Dlx5tm1(cre/ERT2)Zjh
Allelic Composition: Dlx5tm1(cre/ERT2)Zjh/Dlx5+
Genetic Background: involves: C57BL/6 * SJL
|
| MP:0002177 | abnormal outer ear morphology | "malformation or malfunction of any components of the auricles or external acoustic meatus" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: KitW/KitW
Genetic Background: Not Specified
|
| MP:0002238 | abnormal nasal mucosa morphology | "any structural anomaly of the mucous membrane that lines the nasal cavity" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: KitW/KitW
Genetic Background: Not Specified
|
| MP:0002249 | abnormal larynx morphology | "any structural anomaly of the most superior portion of the respiratory tract" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology , 2nd edition:ISBN 0-397-51047-0] |
Show
Allelic Composition: KitW/KitW
Genetic Background: Not Specified
|
| MP:0002260 | abnormal thyroid cartilage morphology | "any structural anomaly of the largest of the laryngeal cartilages " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology , 2nd edition:ISBN 0-397-51047-0] |
Show
Allelic Composition: KitW/KitW
Genetic Background: Not Specified
Allelic Composition: Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: Not Specified
Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
|
| MP:0002428 | abnormal semicircular canal | "anomaly of the organ of balance composed of three long bony tubes of the labyrinth" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
|
| MP:0002544 | brachydactyly | "abnormally short digits" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: Not Specified
|
| MP:0002566 | abnormal sexual interaction | "altered initiation, failure of initiation or incomplete mating behavior" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: KitW/KitW
Genetic Background: Not Specified
|
| MP:0002639 | micrognathia | "abnormally reduced size of the jaws, especially of the mandible" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
Show
Allelic Composition: KitW/KitW
Genetic Background: Not Specified
Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi,Msx1tm1Bero/Msx1tm1Bero
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
|
| MP:0002689 | abnormal molar morphology | "structural defect of the most posterior teeth located on either side of the jaw, and characterized by a large crown and broad chewing surface" [il:Ira Lu , Mouse Genome Informatics Curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: KitW/KitW
Genetic Background: Not Specified
|
| MP:0002741 | small olfactory bulb | "reduced size of the forebrain region that coordinates neuronal signaling involved in the perception of smell; it receives input from the sensory neurons and outputs to the olfactory cortex" [J:79871] |
Show
Allelic Composition: Sox1tm1Vep/Sox1tm1Vep,Sox2tm1Vep/Sox2+
Genetic Background: involves: 129S/SvEv
|
| MP:0002817 | abnormal tooth mineralization | "abnormalities in the process by which calcium salts are deposited into the dental enamel, dentin and cementum " [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: KitW/KitW
Genetic Background: Not Specified
|
| MP:0002820 | abnormal premaxilla morphology | "malformation or absence of the anterior and inner portion of the maxilla" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:76662] |
Show
Allelic Composition: KitW/KitW
Genetic Background: Not Specified
Allelic Composition: Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: Not Specified
|
| MP:0002884 | abnormal branchial arches | "malformation or anomaly in the transient structures of the embryo that develop into regions of the head, neck and ears" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: Not Specified
|
| MP:0003056 | abnormal hyoid bone | "anomalous structure of the U-shaped bone lying between the mandible and the larynx that supports the tongue muscles" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, hdene:Howard Dene, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: Not Specified
Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
|
| MP:0003072 | abnormal metatarsal bone morphology | "anomaly in the five bones of the hindpaws that articulate proximally with the cuneiform and cuboid bones of the tarsus and distally with the phlanges" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, Anatomy of the Rat:Greene, EC, Hafner Publishing Co, 1935] |
Show
Allelic Composition: Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: Not Specified
|
| MP:0003148 | reduced cochlear coiling | "a reduction in cochlear coiling or number of turns; in wild-type mice, the cochlea most commonly exhibits one and three-fourth turns" [J:56294, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator] |
Show
Allelic Composition: KitW/KitW
Genetic Background: Not Specified
Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0003162 | reduced size of lateral semicircular canal | |
Show
Allelic Composition: KitW/KitW
Genetic Background: Not Specified
Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
|
| MP:0003163 | absent posterior semicircular canal | |
Show
Allelic Composition: KitW/KitW
Genetic Background: Not Specified
Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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| MP:0003165 | absent superior semicircular canal | |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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| MP:0003168 | abnormal scala vestibuli morphology | "any malformation or absence of the division of the spiral canal of the cochlea lying on the apical side of the spiral lamina and vestibular membrane" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
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| MP:0003235 | abnormal alisphenoid bone morphology | "malformation in either of the broad curved winglike expanses on each side of the sphenoid bone" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:93183, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
Allelic Composition: Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: Not Specified
Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi,Msx1tm1Bero/Msx1tm1Bero
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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| MP:0003245 | abnormal GABA neuron morphology | "malformation or absence of the neurons that utilize gamma-aminobutyric acid as a neurotransmitter " [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3] |
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Allelic Composition: Sox1tm1Vep/Sox1tm1Vep,Sox2tm1Vep/Sox2+
Genetic Background: involves: 129S/SvEv
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| MP:0003651 | abnormal axon outgrowth | "defect/abnormality in the ability of an axon to extend from a neuron cell body" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator, J:96121] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
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| MP:0003755 | abnormal palate | "anomaly in the roof of the mouth in vertebrates formed anteriorly by a bony projection of the upper jaw (hard palate) and posteriorly by the fold of connective tissue (soft palate) " [ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: Not Specified
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| MP:0003800 | monodactyly | "having only one toe or digit on each extremity" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: Dlx5tm1Levi/Dlx5/Dlx6tm1Levi,Trp63tm1Aam/Trp63tm1Aam
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Trp63tm1Aam/Trp63tm1Aam,Dlx5tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: involves: 129P2/OlaHsd
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| MP:0003869 | ectopic cartilage | "positional abnormality of cartilage" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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| MP:0003931 | absent molars | "missing the most posterior teeth located on either side of the jaw, and characterized by a large crown and broad chewing surface" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi,Msx1tm1Bero/Msx1tm1Bero
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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| MP:0003932 | abnormal molar crown morphology | "defects in the upper part of the molar, which is normally covered with enamel " [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
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| MP:0003935 | abnormal craniofacial development | "anomaly in the process of forming the face and/or cranium" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: Not Specified
Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
Allelic Composition: Dlx5tm1Jlr/Dlx5tm1Jlr
Genetic Background: B6.129X1-Dlx5tm1Jlr
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| MP:0004136 | abnormal tongue muscle morphology | "anomalous structure or development of the muscular portion of the tongue" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
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| MP:0004204 | absent stapes | "absence of the smallest and innermost of the three auditory ossicles" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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| MP:0004237 | abnormal pterygoid muscle morphology | "any structural anomaly of the muscles descending from the sphenoid bone to the lower jaw including the internal, or medial, pterygoid muscle and external, or lateral, pterygoid muscle. Action of the former is closing the jaws and that of the latter is opening the jaws, protruding the mandible, and moving the mandible from side to side" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
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| MP:0004249 | abnormal crista ampullaris morphology | "anomaly in the elevation found on the inner surface of the ampullae of each semicircular duct; filaments of the vestibular nerve pass through the crista to reach hair cells on its surface; the hair cells are capped by the cupula, a gelatinous protein-polysaccharide mass" [J:60193, MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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| MP:0004279 | abnormal rostral migratory stream morphology | "any structural anomaly of the transient structure formed by neurons migrating from the subventricular zone into the olfactory bulbs" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Dlx5tm1Jlr/Dlx5tm1Jlr
Genetic Background: B6.129X1-Dlx5tm1Jlr
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| MP:0004311 | otic vesicle hypoplasia | "underdevelopment of the simple epithelial sac formed from the otic placode that gives rise to the structures of the inner ear, usually due to a reduction in cell number" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd
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| MP:0004330 | abnormal saccular macula morphology | "any structural abnormalities in the oval neuroepithelial sensory receptor in the anterior wall of the saccule; hair cells of the neuroepithelium support the statoconial membrane and have terminal arborizations of vestibular nerve fibers around their bodies" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd
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| MP:0004333 | abnormal utricular macula morphology | "any structural abnormalities in the neuroepithelial sensory receptor in the inferolateral wall of the utricle; hair cells of the neuroepithelium support the statoconial membrane and have terminal arborizations of vestibular nerve fibers around their bodies; normally sensitive to linear acceleration in the longitudinal axis of the body and to gravitational influences" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd
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| MP:0004335 | enlarged utricle | "increased size of the larger of the two sacs in the vestibule" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd
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| MP:0004384 | small interparietal bone | "reduced size of the bone of the cranium that lies above and anterior to the occipital bone in some mammals" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
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| MP:0004409 | abnormal neuroepithelium of ampullary crest | "any structural abnormality in the specialized sensory hair cells of the ampullary crest of the ampulla of each semicircular duct" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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| MP:0004418 | small parietal bone | "reduced size of the curved bone forming part of the vault of the cranium" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
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| MP:0004423 | abnormal squamosal bone morphology | "any structural anomaly of the thin, platelike part of the temporal bone" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
Allelic Composition: Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: Not Specified
Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi,Msx1tm1Bero/Msx1tm1Bero
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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| MP:0004439 | absent Meckel s cartilage | "absence of this cartilage bar in the mandibular arch that forms a temporary supporting structure in the embryonic mandible; gives rise to middle ear bones and sphenomandibular and anterior malleolar ligaments" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: Not Specified
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| MP:0004444 | small supraoccipital bone | "reduced size of the bone on the dorsal side of the great foramen of the skull, usually forming a part of the occipital in the adult, but distinct in the young" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
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| MP:0004452 | abnormal pterygoid process morphology | "any structural anomaly of the process projecting downward from either side of the sphenoid bone, in vertebrates divided into two plates, an inner and an outer (sometimes called the lateral and medial); the posterior nares pass through the space, called the pterygoid fossa, between the processes" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: Not Specified
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| MP:0004453 | abnormal pterygoid bone morphology | "any structural anomaly of the bone region which corresponds to the inner plate of the pterygoid process of the mammalian skull" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi,Msx1tm1Bero/Msx1tm1Bero
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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| MP:0004470 | small nasal bone | "reduced size of either of two rectangular bone plates forming the bridge of the nose" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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| MP:0004471 | short nasal bone | "reduced length of either of two rectangular bone plates forming the bridge of the nose" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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| MP:0004477 | turbinate hypoplasia | "underdevelopment or reduced size, usually due to a reduced number of cells, in the small curved bones that extends horizontally along the lateral wall of the nasal passage" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
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| MP:0004540 | small maxilla | "reduced size of the upper bony framework of the mouth where the superior teeth are held" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
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| MP:0004594 | abnormal mandibular coronoid process morphology | "any structural anomaly of the thin, flattened, triangular eminence that arises from the upper surface of the mandibular ramus (perpendicular portion); includes the attachment site to the temporal muscle" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
Allelic Composition: Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: Not Specified
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| MP:0004595 | abnormal mandibular condyloid process morphology | "any structural anomaly of the round bump of bone and constricted neck portion that arises from the upper surface of the mandibular ramus (perpendicular portion) and articulates with the articular disk of the temporomandibular joint" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
Allelic Composition: Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: Not Specified
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| MP:0004596 | abnormal mandibular angle morphology | "any structural anomaly of the portion of the mandible where the body of the mandible (horizontal portion) and the rami (perpendicular portions) meet; these normally unite nearly at right angles" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
Allelic Composition: Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: Not Specified
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| MP:0004665 | abnormal stapedial artery morphology | "any structural abnormality in the small artery that passes through the ring of the stapes; while the stapedial artery is a temporary artery thought to disappear at late embryonic stage in humans, the mouse stapedial artery is complete by E13 and persists into adulthood " [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
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| MP:0004726 | abnormal nasal capsule morphology | "any structural abnormality in the cartilage around the developing nasal cavity of the embryo" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
Allelic Composition: Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: Not Specified
Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi,Msx1tm1Bero/Msx1tm1Bero
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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| MP:0004912 | absent mandibular coronoid process | "absence of the thin, flattened, triangular eminence that arises from the upper surface of the mandibular ramus (perpendicular portion)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi,Msx1tm1Bero/Msx1tm1Bero
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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| MP:0005105 | abnormal middle ear ossicle morphology | "anomalous structure or development of the three small bones of the middle ear" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: Not Specified
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| MP:0005230 | ectrodactyly | "absence of the middle rays, i.e., the central digits of the paws; usually associated with cleft paws and may also include syndactyly or aplasia of remaining digits" [OMIM:Online Mendelian Inheritance in Man] |
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Allelic Composition: Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: Not Specified
Allelic Composition: Dlx5tm1Levi/Dlx5/Dlx6tm1Levi,Trp63tm1Aam/Trp63tm1Aam
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Trp63tm1Aam/Trp63tm1Aam,Dlx5tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: involves: 129P2/OlaHsd
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| MP:0005236 | abnormal olfactory nerve morphology | "anomalous structure of the first cranial nerve, which conveys the sense of smell" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Sox1tm1Vep/Sox1tm1Vep,Sox2tm1Vep/Sox2+
Genetic Background: involves: 129S/SvEv
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| MP:0005269 | abnormal occipital bone morphology | "anomalous structure of the bone at the lower, posterior part of the skull" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
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| MP:0005270 | abnormal zygomatic bone morphology | "anomalous structure of the bone that forms the prominence of the cheek" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: Not Specified
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| MP:0005271 | abnormal lacrimal bone morphology | "anomalous structure of the irregularly thin plate that forms part of the medial wall of the orbit behind the frontal process of the maxilla" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
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| MP:0005274 | abnormal viscerocranium morphology | "anomalous structure or formation of the part of the skull that comprises the facial bones " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: Not Specified
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| MP:0005306 | abnormal phalanx morphology | "aberrant structure of any of the long bones of the digits" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: Not Specified
Allelic Composition: Dlx5tm1Levi/Dlx5/Dlx6tm1Levi,Trp63tm1Aam/Trp63tm1Aam
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Trp63tm1Aam/Trp63tm1Aam,Dlx5tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: involves: 129P2/OlaHsd
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| MP:0005358 | abnormal incisor morphology | "structural defect of the long pointed teeth; most anterior and prominent in the jaw" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:85574] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
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| MP:0005587 | abnormal Meckel s cartilage morphology | "structural anomaly of this cartilage bar in the mandibular arch that forms a temporary supporting structure in the embryonic mandible; gives rise to middle ear bones and sphenomandibular and anterior malleolar ligaments" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:17694] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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| MP:0006020 | reduced size of tympanic ring | "smaller than average tympanic ring" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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| MP:0006033 | abnormal external auditory canal | "malformation of the canal that connects the outer and middle ear" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:57313] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
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| MP:0006089 | abnormal saccule morphology | "malformation in the smaller of the two sacs in the vestibule" [smb:Susan M Bello, Mouse Genome Informatics Curator, Taber s Cyclopedic Medical Dictionary:19th edition: ISBN N 0-8036-0655-99, J:92940] |
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Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd
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| MP:0006289 | otic capsule hypoplasia | "underdevelopment or reduced size, usually due to a reduced number of cells, of the cartilage or bony capsule surrounding the inner ear mechanism" [J:100584, MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
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| MP:0006306 | abnormal nasal pit morphology | "malformation of one or both of a pair of depressions formed in the developing face that give rise to the rostral portion of the nasal meatus" [J:119812, MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Dlx5tm1Jlr/Dlx5tm1Jlr
Genetic Background: B6.129X1-Dlx5tm1Jlr
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| MP:0006337 | abnormal first branchial arch morphology | "anomaly in the structure of the first arch which contributes to development of mastication muscles, maxilla, mandible, incus, malleus, Meckel s cartilage, trigeminal nerve, and maxillary artery" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: Not Specified
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| MP:0008023 | abnormal styloid process morphology | "any structural abnormality in the slender needle-like pointed projection that runs downward and slightly forward from the base of the inferior surface of the petrous portion of the temporal bone where it joins the tympanic portion; it gives attachment to the styloglossus, stylohyoid, and stylopharyngeus muscles and the stylohyoid and stylomandibular ligaments" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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| MP:0008065 | short endolymphatic duct | "length reduction or truncation of the small membranous canal which connects with both saccule and utricle of the membranous labyrinth, passes through the aqueduct of vestibule, and terminates in the endolymphatic sac" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd
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| MP:0008271 | abnormal bone ossification | "any anomaly in the formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance" [GO:0001503] |
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Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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| MP:0008378 | small malleal processus brevis | "reduced size of the projection extending from the base of the manubrium of the malleus which contacts the upper part of the tympanic membrane" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
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| MP:0008379 | absent head of malleus | "absence of the rounded portion of the malleus articulating with the body of the incus" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi,Msx1tm1Bero/Msx1tm1Bero
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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| MP:0008380 | abnormal gonial bone morphology | "any structural abnormality of the investing bone that lies on the surface of the malleus" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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| MP:0008395 | abnormal osteoblast differentiation | "atypical production of or inability to produce bone-forming cells, which normally form an osseous matrix (osteoid) in which they become enclosed as an osteocytes" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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| MP:0008789 | abnormal olfactory epithelium morphology | "any structural anomaly in the epithelial cells that line the interior of the nose" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Dlx5tm1Jlr/Dlx5tm1Jlr
Genetic Background: B6.129X1-Dlx5tm1Jlr
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| MP:0009247 | meteorism | "swelling of the abdomen resulting from gas in the intestinal or peritoneal cavity" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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| MP:0009546 | absent gastric milk in neonates | "failure of nursing offspring to ingest milk as indicated by stomach content" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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| MP:0009888 | palatal shelves fail to meet at midline | "polarized growth towards the midline following palatal shelf elevation does not occur" [PMID:16942766] |
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Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi,Msx1tm1Bero/Msx1tm1Bero
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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| MP:0009890 | cleft secondary palate | "congenital fissure of the tissues normally uniting to form the secondary palate" [PMID:16680722] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi,Msx1tm1Bero/Msx1tm1Bero
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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| MP:0009893 | cleft primary palate | "congenital fissure of the tissues normally uniting to form the primary palate" [PMID:16680722] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
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| MP:0009897 | decreased maxillary shelf size | "reduced size of the bony projection of the maxilla that normally fuses with palatine shelf to form secondary (hard) palate" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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| MP:0009901 | abnormal frontonasal prominence morphology | "any structural anomaly of an unpaired facial process in the embryo formed from the tissues surrounding the forebrain vesicle that develops into the forehead and bridge of the nose/snout" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Dlx5tm1Jlr/Dlx5tm1Jlr
Genetic Background: B6.129X1-Dlx5tm1Jlr
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| MP:0009902 | abnormal lateral nasal prominence morphology | "any structural anomaly of the lateral area of the two branches of a horseshoe-shaped mesenchymal swelling in the future nasal region of the embryo; it separates the olfactory pit from the developing eye and the ala of the nose/snout develops from it" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
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| MP:0009913 | abnormal hyoid bone greater horn morphology | "any structural anomaly of the larger and more lateral of the paired processes on either side of the hyoid bone" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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| MP:0009914 | abnormal hyoid bone lesser horn morphology | "any structural anomaly of shorter and more medial of the paired processes on either side of the hyoid bone" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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| MP:0009918 | abnormal stylohyoid ligament morphology | "any structrual anomaly of the fibrous cord that connects the tip of the styloid process of the temporal bone to the lesser horn of the hyoid bone" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: Not Specified
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| MP:0009942 | abnormal olfactory bulb granule cell morphology | "any structural anomaly of the main intrinsic GABAergic neuron in the granule cell layer of the main olfactory bulb; dendrites of these cells receive synaptic input from mitral and tufted cell lateral dendrites in the external plexiform layer, and have synaptic outputs on those dendrites through reciprocal dendrodendritic synapses" [NLX:nifext_123 "NeuroLex.org"] |
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Allelic Composition: Dlx5tm1Jlr/Dlx5tm1Jlr
Genetic Background: B6.129X1-Dlx5tm1Jlr
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| MP:0009943 | abnormal olfactory bulb periglomerular cell morphology | "any structural anomaly of the small neuron in the glomerular layer of the olfactory bulb whose dendrites arborize within a glomerulus, where it receives synaptic input from olfactory receptor cell axon terminals, and also engages in dendrodendritic interactions with mitral and tufted cell dendrites; uses both GABA and dopamine as a neurotransmitter" [NLX:nlx_cell_091202 "NeuroLex.org"] |
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Allelic Composition: Dlx5tm1Jlr/Dlx5tm1Jlr
Genetic Background: B6.129X1-Dlx5tm1Jlr
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| MP:0009954 | abnormal mitral cell morphology | "any structural anomaly of the large glutaminergic nerve cells whose dendrites synapse with axons of the olfactory receptor neurons in the glomerular layer of the olfactory bulb, and whose axons pass centrally in the olfactory tract to the olfactory cortex" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Dlx5tm1Jlr/Dlx5tm1Jlr
Genetic Background: B6.129X1-Dlx5tm1Jlr
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| MP:0010029 | abnormal basicranium morphology | "any structural anomaly of the sloping floor of the cranial cavity that is comprised of parts of the ethmoidal, occipital and sphenoid bones" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: Not Specified
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| MP:0010743 | delayed suture closure | "late onset of the fusion of the bones of the skull" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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| MP:0010939 | abnormal mandibular prominence morphology | |
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Allelic Composition: Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: Not Specified
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| MP:0011085 | complete postnatal lethality | "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
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Allelic Composition: Dmrta1tm1.1Zark/Dmrta1+
Genetic Background: involves: 129S1/Sv * FVB/N
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| MP:0011087 | complete neonatal lethality | "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith] |
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Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi,Msx1tm1Bero/Msx1tm1Bero
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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| MP:0011089 | complete perinatal lethality | "death of all organisms of a given genotype in a population within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
Allelic Composition: Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: Not Specified
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| MP:0011101 | partial prenatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
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| MP:0012176 | abnormal head development | "anomaly in the process in which the anatomical structures of the head are generated and organized" [GO:0060323] |
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Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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| MP:0013595 | absent vomeronasal organ | "lacking the tubular, crescent-sensory organ with a luminal epithelium that contains chemosensitive receptor cells with microvilli that are thought to detect pheromones and transmit signals to the remainder of the accessory olfactory system" [MGI:csmith] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
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| MP:0013597 | small vomeronasal organ | "reduced size of the tubular, crescent-sensory organ with a luminal epithelium that contains chemosensitive receptor cells with microvilli that are thought to detect pheromones and transmit signals to the remainder of the accessory olfactory system" [http://ctrgenpath.net/static/atlas/mousehistology/Windows/senses/jacobsonorgan.html, http://en.wikipedia.org/wiki/Vomeronasal_organ#Structure, MGI:csmith] |
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Allelic Composition: Dlx5tm1Jlr/Dlx5tm1Jlr
Genetic Background: B6.129X1-Dlx5tm1Jlr
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| MP:0013933 | short Meckel s cartilage | |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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| MP:0014155 | absent olfactory epithelium | "absence of the epithelial cells that line the interior of the nose" [MGI:csmith] |
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Allelic Composition: Dlx5tm1Jlr/Dlx5tm1Jlr
Genetic Background: B6.129X1-Dlx5tm1Jlr
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| MP:0014166 | ectopic cranial bone | "the appearance of an extra bone structure at an atypical location in or near the cranium" [MGI:csmith] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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| MP:0020137 | decreased bone mineralization | "decrease in the rate at which minerals are deposited into bone" [] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
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| MP:0020350 | fused pharyngeal arches | "failure of two or more arches to fully separate" [ORCID: orcid.org/0000-0003-4606-0597, PMID:22319578] |
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Allelic Composition: Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: Not Specified
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| MP:0030029 | wide cranial sutures | "an abnormally increased width of one or more cranial sutures for age-related norms, generally resulting from delayed suture closure" [HP:0010537] |
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Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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| MP:0030030 | Wormian bones | "presence of small extra bone segments, usually of irregular shape and variable size, arising in fontanelles and/or adjacent to or along the cranial sutures, and formed from additional and separate centers of ossification of the cranium; in humans, Wormian bones are most frequently located in the lambdoid or coronal suture, and have been seen in the fontanelles, particularly the posterior fontanelle" [https://www.kenhub.com/en/library/anatomy/accessory-bones-of-the-skull, PMID:23959948] |
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Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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| MP:0030055 | small lacrimal bone | "reduced size of the thin plate that forms part of the medial wall of the orbit behind the frontal process of the maxilla" [] {comment="MGI:anna"} |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
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| MP:0030089 | short lower incisors | "reduced length of the lower set of long teeth that are the most anterior and prominent in the jaw" [MGI:anna] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
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| MP:0030090 | short upper incisors | "reduced length of the upper set of long teeth that are the most anterior and prominent in the jaw" [MGI:anna] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
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| MP:0030148 | abnormal mylohyoid muscle morphology | "any structural anomaly of the flat and triangular paired muscle that runs from the mandible to the hyoid bone forming the muscular floor of the oral cavity of the mouth; it is a suprahyoid muscle derived from the first pharyngeal arch that is situated immediately superior to the anterior belly of the digastric muscle" [] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
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| MP:0030187 | abnormal epitympanic recess morphology | "any structural anomaly of the upper portion of the tympanic cavity located above the tympanic membrane; it contains the head of the malleus and the body of the incus" [https://radiopaedia.org/articles/middle-ear, https://www.drugs.com/dict/epitympanum.html] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
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| MP:0030199 | deviated nasal septum | "displacement of the nasal septum in which the top of the cartilaginous ridge leans to the left or the right, causing obstruction of the affected nasal passage; normally, the septum lies centrally, and thus the nasal passages are symmetrical" [HP:0004411, https://en.wikipedia.org/wiki/Nasal_septum_deviation] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
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| MP:0030203 | short nasal septum | "reduced length of the dividing wall that runs down the midline of the nose, separating the nasal cavity into the two nostrils" [MGI:anna] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
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| MP:0030208 | abnormal intrinsic tongue muscle morphology | "any structural anomaly of any of the four paired muscles that originate and insert within the tongue, running along its length; these muscles alter the shape of the tongue by lengthening and shortening it, curling and uncurling its apex and edges, and flattening and rounding its surface; they include the superior longitudinal muscle, the inferior longitudinal muscle, the vertical muscle, and the transverse muscle" [https://en.wikipedia.org/wiki/Tongue, https://www.imaios.com/en/e-Anatomy/Anatomical-Parts/Muscles-of-tongue, MGI:anna] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
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| MP:0030250 | frontonasal prominence hypoplasia | "underdevelopment or reduced size, usually due to a reduced number of cells, of the unpaired embryonic process that is formed from the tissues surrounding the forebrain vesicle and develops into the forehead and bridge of the nose/snout" [MGI:anna] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
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| MP:0030266 | small vomer bone | "reduced size of the triangular flat bone of the nasal septum" [MGI:anna] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
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| MP:0030299 | lower jaw to upper jaw transformation | "homeotic transformation of lower jaw (mandibular) elements into upper jaw-like (maxillary) structures" [MGI:anna, PMID:22560091] |
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Allelic Composition: Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: Not Specified
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| MP:0030321 | abnormal tegmen tympani morphology | "any structural anomaly of the thin plate of bone which separates the middle ear (tympanic) cavity from the dura of the middle cranial fossa and forms the roof of the middle ear cavity; it is formed in part by the petrous portion of the temporal bone, and the squamous portion of the temporal bone" [http://www.drtbalu.com/anat_middleear.html, https://medical-dictionary.thefreedictionary.com/tegmen+tympani] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
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| MP:0030323 | short styloid process | "length reduction or truncation of the slender needle-like pointed projection that runs downward and slightly forward from the base of the inferior surface of the petrous portion of the temporal bone where it joins the tympanic portion; it gives attachment to the styloglossus, stylohyoid, and stylopharyngeus muscles and the stylohyoid and stylomandibular ligaments" [MGI:anna] |
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Allelic Composition: Dlx5tm1Levi/Dlx5tm1Levi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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| MP:0030383 | small presphenoid bone | "reduced size of the anterior part of the body of the sphenoid bone in front of the basisphenoid; it is usually a separate bone in the young or fetus, but becomes a part of the sphenoid in the adult" [MGI:anna] |
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Allelic Composition: Dlx5/Dlx6tm1Levi/Dlx5/Dlx6tm1Levi
Genetic Background: Not Specified
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| MP:0030422 | abnormal outer ear cartilage morphology | "any structural anomaly of the elastic cartilage components of the auricles and/or external acoustic meatus" [MGI:anna] |
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Allelic Composition: KitW/KitW
Genetic Background: Not Specified
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