ENSGALG00000039615


Gallus gallus

Features
Gene ID: ENSGALG00000039615
  
Biological name :MSN
  
Synonyms : moesin / MSN
  
Possible biological names infered from orthology : P26038 / P26041
  
Species: Gallus gallus
  
Chr. number: 4
Strand: 1
Band:
Gene start: 132734
Gene end: 172589
  
Corresponding Affymetrix probe sets: Gga.3145.1.S1_x_at (Chicken Array)   Gga.3145.2.S1_a_at (Chicken Array)   Gga.3145.3.S1_at (Chicken Array)   Gga.3145.3.S1_a_at (Chicken Array)   GgaAffx.2921.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000045465
Ensembl peptide - ENSGALP00000057943
Ensembl peptide - ENSGALP00000057514
Ensembl peptide - ENSGALP00000053285
NCBI entrez gene - 422173     See in Manteia.
RefSeq - NM_001031112
RefSeq Peptide - NP_001026283
swissprot - A0A1D5PY94
swissprot - A0A1D5PX24
swissprot - A0A1D5PKC8
swissprot - Q5F347
Ensembl - ENSGALG00000039615
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 msnaENSDARG00000058128Danio rerio
 msnbENSDARG00000028740Danio rerio
 MSNENSG00000147065Homo sapiens
 MsnENSMUSG00000031207Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RDX / radixin / P26043* / P35241*ENSGALG0000001715381
EZRENSGALG0000001374272
NF2 / neurofibromin 2 / P35240* / P46662* / Merlin *ENSGALG0000000807345
FARP1 / FERM, ARH/RhoGEF and pleckstrin domain protein 1 / F8VPU2* / Q9Y4F1* / FERM, ARHGEF and pleckstrin domain-containing protein 1 *ENSGALG0000001688626
FARP2 / FERM, ARH/RhoGEF and pleckstrin domain protein 2 / O94887* / Q91VS8* / FERM, ARHGEF and pleckstrin domain-containing protein 2 *ENSGALG0000000578825
FRMD7 / FERM domain containing 7 / A2AD83* / Q6ZUT3* / FERM domain-containing protein 7 *ENSGALG0000002384319
MYLIP / myosin regulatory light chain interacting protein / Q8BM54* / Q8WY64* / E3 ubiquitin-protein ligase MYLIP *ENSGALG0000001270416
ENSGALG0000000236714


Protein motifs (from Interpro)
Interpro ID Name
 IPR000299  FERM domain
 IPR000798  Ezrin/radixin/moesin-like
 IPR008954  Moesin tail domain superfamily
 IPR011174  Ezrin/radixin/moesin
 IPR011259  Ezrin/radixin/moesin, C-terminal
 IPR011993  PH-like domain superfamily
 IPR014352  FERM/acyl-CoA-binding protein superfamily
 IPR018979  FERM, N-terminal
 IPR018980  FERM, C-terminal PH-like domain
 IPR019747  FERM conserved site
 IPR019748  FERM central domain
 IPR019749  Band 4.1 domain
 IPR029071  Ubiquitin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001771 immunological synapse formation IEA
 biological_processGO:0007159 leukocyte cell-cell adhesion IEA
 biological_processGO:0008360 regulation of cell shape IEA
 biological_processGO:0008361 regulation of cell size IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0022612 gland morphogenesis IEA
 biological_processGO:0022614 membrane to membrane docking IEA
 biological_processGO:0042098 T cell proliferation IEA
 biological_processGO:0045198 establishment of epithelial cell apical/basal polarity IEA
 biological_processGO:0050900 leukocyte migration IEA
 biological_processGO:0061028 establishment of endothelial barrier IEA
 biological_processGO:0070489 T cell aggregation IEA
 biological_processGO:0071394 cellular response to testosterone stimulus IEA
 biological_processGO:0071803 positive regulation of podosome assembly IEA
 biological_processGO:0072678 T cell migration IEA
 biological_processGO:1902115 regulation of organelle assembly IEA
 biological_processGO:1902966 positive regulation of protein localization to early endosome IEA
 biological_processGO:1903364 positive regulation of cellular protein catabolic process IEA
 biological_processGO:2000401 regulation of lymphocyte migration IEA
 biological_processGO:2000643 positive regulation of early endosome to late endosome transport IEA
 cellular_componentGO:0001931 uropod IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005902 microvillus IEA
 cellular_componentGO:0005925 focal adhesion IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016323 basolateral plasma membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0030175 filopodium IEA
 cellular_componentGO:0031143 pseudopodium IEA
 cellular_componentGO:0043209 myelin sheath IEA
 cellular_componentGO:0045177 apical part of cell IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:0071437 invadopodium IEA
 cellular_componentGO:0071944 cell periphery IEA
 molecular_functionGO:0003725 double-stranded RNA binding IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0008092 cytoskeletal protein binding IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0050839 cell adhesion molecule binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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