ENSGALG00000040368


Gallus gallus

Features
Gene ID: ENSGALG00000040368
  
Biological name :CALR
  
Synonyms : CALR / calreticulin
  
Possible biological names infered from orthology : P14211 / P27797
  
Species: Gallus gallus
  
Chr. number: 30
Strand: -1
Band:
Gene start: 10644
Gene end: 14298
  
Corresponding Affymetrix probe sets: Gga.11632.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000046274
Ensembl peptide - ENSGALP00000055824
NCBI entrez gene - 100859104     See in Manteia.
RefSeq - XM_015300202
swissprot - A0A1D5P0U5
swissprot - A0A1D5PSD8
Ensembl - ENSGALG00000040368
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 calrENSDARG00000076290Danio rerio
 CALRENSG00000179218Homo sapiens
 CalrENSMUSG00000003814Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CALR3 / calreticulin 3 / Q96L12* / Q9D9Q6*ENSGALG0000000391454
CANX / calnexin / P27824* / P35564*ENSGALG0000003214836
CLGN / calmegin / O14967* / P52194* / Mus musculus calmegin (Clgn), transcript variant 2, mRNA.*ENSGALG0000000982635


Protein motifs (from Interpro)
Interpro ID Name
 IPR001580  Calreticulin/calnexin
 IPR009033  Calreticulin/calnexin, P domain superfamily
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR018124  Calreticulin/calnexin, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0002502 peptide antigen assembly with MHC class I protein complex IEA
 biological_processGO:0006457 protein folding IEA
 biological_processGO:0006611 protein export from nucleus IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0010595 positive regulation of endothelial cell migration IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0017148 negative regulation of translation IEA
 biological_processGO:0030866 cortical actin cytoskeleton organization IEA
 biological_processGO:0033144 negative regulation of intracellular steroid hormone receptor signaling pathway IEA
 biological_processGO:0034504 protein localization to nucleus IEA
 biological_processGO:0040020 regulation of meiotic nuclear division IEA
 biological_processGO:0045665 negative regulation of neuron differentiation IEA
 biological_processGO:0045740 positive regulation of DNA replication IEA
 biological_processGO:0045787 positive regulation of cell cycle IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0048387 negative regulation of retinoic acid receptor signaling pathway IEA
 biological_processGO:0050766 positive regulation of phagocytosis IEA
 biological_processGO:0050821 protein stabilization IEA
 biological_processGO:0071157 negative regulation of cell cycle arrest IEA
 biological_processGO:0090398 cellular senescence IEA
 biological_processGO:1900026 positive regulation of substrate adhesion-dependent cell spreading IEA
 biological_processGO:1901164 negative regulation of trophoblast cell migration IEA
 biological_processGO:1901224 positive regulation of NIK/NF-kappaB signaling IEA
 biological_processGO:2000510 positive regulation of dendritic cell chemotaxis IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005635 nuclear envelope IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005788 endoplasmic reticulum lumen IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005844 polysome IEA
 cellular_componentGO:0009897 external side of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0042824 MHC class I peptide loading complex IEA
 cellular_componentGO:0044322 endoplasmic reticulum quality control compartment IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0003729 mRNA binding IEA
 molecular_functionGO:0005178 integrin binding IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0030246 carbohydrate binding IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA
 molecular_functionGO:0050681 androgen receptor binding IEA
 molecular_functionGO:0051082 unfolded protein binding IEA


Pathways (from Reactome)
Pathway description
ER-Phagosome pathway
Calnexin/calreticulin cycle
Antigen Presentation: Folding, assembly and peptide loading of class I MHC


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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