ENSGALG00000040606


Gallus gallus

Features
Gene ID: ENSGALG00000040606
  
Biological name :RAC3
  
Synonyms : RAC3 / Rac family small GTPase 3
  
Possible biological names infered from orthology : P60763 / P60764 / RAS-related C3 botulinum substrate 3
  
Species: Gallus gallus
  
Chr. number: 18
Strand: -1
Band:
Gene start: 5042896
Gene end: 5049375
  
Corresponding Affymetrix probe sets: Gga.2936.1.S1_at (Chicken Array)   Gga.2936.1.S2_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000045177
Ensembl peptide - ENSGALP00000064549
Ensembl peptide - ENSGALP00000062120
Ensembl peptide - ENSGALP00000059395
Ensembl peptide - ENSGALP00000058312
Ensembl peptide - ENSGALP00000051535
Ensembl peptide - ENSGALP00000050965
NCBI entrez gene - 395870     See in Manteia.
RefSeq - NM_205016
RefSeq Peptide - NP_990347
swissprot - A0A1L1RKV2
swissprot - A0A1D5PZA2
swissprot - A0A1D5PFH1
swissprot - A0A1D5PDW7
swissprot - A0A1L1S0B9
swissprot - O93466
swissprot - A0A1L1RTH8
Ensembl - ENSGALG00000040606
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rac3aENSDARG00000090062Danio rerio
 rac3bENSDARG00000020795Danio rerio
 RAC3ENSG00000169750Homo sapiens
 Rac3ENSMUSG00000018012Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RAC1 / Rac family small GTPase 1 / P63000* / P63001* / RAS-related C3 botulinum substrate 1*ENSGALG0000000713094
RAC2 / Rac family small GTPase 2 / P15153* / Q05144* / Ras-related C3 botulinum toxin substrate 2 *ENSGALG0000001245689
RHOGLENSGALG0000000547569
RHOG / ras homolog family member G / P84095* / P84096*ENSGALG0000002699568
CDC42 / Q90694 / Cell division control protein 42 homolog / P60766* / P60953* / cell division cycle 42* / Cell division control *ENSGALG0000000479668
RHOQ / rho-related GTP-binding protein RhoQ / P17081* / Q8R527* / ras homolog family member Q*ENSGALG0000001001063
RHOJ / rho-related GTP-binding protein RhoJ / Q9ER71* / Q9H4E5* / ras homolog family member J*ENSGALG0000001185560
RHOU* / Q7L0Q8* / Q9EQT3* / ras homolog family member U* / Rho-related GTP-binding protein RhoU *ENSGALG0000002573857
RHOV / ras homolog family member V / Q8VDU1* / Q96L33* / Rho-related GTP-binding protein RhoV *ENSGALG0000002804753
RHOBTB1 / Rho related BTB domain containing 1 / O94844* / Q9DAK3* / Rho-related BTB domain-containing protein 1 *ENSGALG0000000307344
RHOBTB2 / Rho related BTB domain containing 2 / Q91V93* / Q9BYZ6* / Rho-related BTB domain-containing protein 2 *ENSGALG0000003402043


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007264 small GTPase mediated signal transduction IEA
 biological_processGO:0014041 regulation of neuron maturation IEA
 biological_processGO:0021894 cerebral cortex GABAergic interneuron development IEA
 biological_processGO:0022604 regulation of cell morphogenesis IEA
 biological_processGO:0030031 cell projection assembly IEA
 biological_processGO:0030036 actin cytoskeleton organization IEA
 biological_processGO:0031175 neuron projection development IEA
 biological_processGO:0031532 actin cytoskeleton reorganization IMP
 biological_processGO:0033630 positive regulation of cell adhesion mediated by integrin IEA
 biological_processGO:0048812 neuron projection morphogenesis IMP
 biological_processGO:0048873 homeostasis of number of cells within a tissue IEA
 biological_processGO:0050885 neuromuscular process controlling balance IEA
 biological_processGO:0050905 neuromuscular process IEA
 biological_processGO:0051932 synaptic transmission, GABAergic IEA
 biological_processGO:1900026 positive regulation of substrate adhesion-dependent cell spreading IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0012505 endomembrane system IEA
 cellular_componentGO:0030426 growth cone IEA
 cellular_componentGO:0031941 filamentous actin IEA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:0070852 cell body fiber IDA
 cellular_componentGO:0071944 cell periphery IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0044877 protein-containing complex binding IDA
 molecular_functionGO:0048306 calcium-dependent protein binding IEA


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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