ENSGALG00000040908


Gallus gallus

Features
Gene ID: ENSGALG00000040908
  
Biological name :HIP1
  
Synonyms : HIP1 / huntingtin interacting protein 1
  
Possible biological names infered from orthology : O00291 / Q8VD75
  
Species: Gallus gallus
  
Chr. number: 19
Strand: -1
Band:
Gene start: 328871
Gene end: 345898
  
Corresponding Affymetrix probe sets: GgaAffx.22557.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000052993
NCBI entrez gene - 770683     See in Manteia.
RefSeq - XM_015295909
RefSeq - XM_015295912
RefSeq - XM_015295910
RefSeq - XM_015295911
swissprot - A0A1D5PJJ8
Ensembl - ENSGALG00000040908
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hip1ENSDARG00000062972Danio rerio
 HIP1ENSG00000127946Homo sapiens
 Hip1ENSMUSG00000039959Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HIP1R / huntingtin-interacting protein 1-related protein / O75146* / Q9JKY5* / huntingtin interacting protein 1 related*ENSGALG0000003151150
TLN1 / talin-1 / P26039* / Q9Y490*ENSGALG0000000254823
TLN2* / Q9Y4G6* / talin 2*ENSGALG0000000362812
TLN2* / Q9Y4G6* / talin 2*ENSGALG000000466182
TLN2* / Q9Y4G6* / talin 2*ENSGALG000000461551
TLN2* / Q9Y4G6* / talin 2*ENSGALG000000298161
TLN2* / Q9Y4G6* / talin 2*ENSGALG000000380780


Protein motifs (from Interpro)
Interpro ID Name
 IPR002558  I/LWEQ domain
 IPR011417  AP180 N-terminal homology (ANTH) domain
 IPR030224  Sla2 family
 IPR030554  Huntingtin-interacting protein 1
 IPR032422  Huntingtin-interacting protein 1, clathrin-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:0042981 regulation of apoptotic process IEA
 biological_processGO:0045742 positive regulation of epidermal growth factor receptor signaling pathway IEA
 biological_processGO:0048260 positive regulation of receptor-mediated endocytosis IEA
 biological_processGO:0048268 clathrin coat assembly IEA
 biological_processGO:0050821 protein stabilization IEA
 biological_processGO:0072583 clathrin-dependent endocytosis IEA
 biological_processGO:0097190 apoptotic signaling pathway IEA
 biological_processGO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0030122 AP-2 adaptor complex IEA
 cellular_componentGO:0030136 clathrin-coated vesicle IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 cellular_componentGO:0098793 presynapse IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005543 phospholipid binding IEA
 molecular_functionGO:0030276 clathrin binding IEA
 molecular_functionGO:0032051 clathrin light chain binding IEA
 molecular_functionGO:0032266 phosphatidylinositol-3-phosphate binding IEA
 molecular_functionGO:0035091 phosphatidylinositol binding IEA
 molecular_functionGO:0035612 AP-2 adaptor complex binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0043325 phosphatidylinositol-3,4-bisphosphate binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA
 molecular_functionGO:0051015 actin filament binding IEA
 molecular_functionGO:0080025 phosphatidylinositol-3,5-bisphosphate binding IEA


Pathways (from Reactome)
Pathway description
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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