ENSGALG00000041036


Gallus gallus

Features
Gene ID: ENSGALG00000041036
  
Biological name :FTO
  
Synonyms : alpha-ketoglutarate-dependent dioxygenase FTO / FTO
  
Possible biological names infered from orthology : FTO, alpha-ketoglutarate dependent dioxygenase / Q8BGW1 / Q9C0B1
  
Species: Gallus gallus
  
Chr. number: 11
Strand: -1
Band:
Gene start: 4752497
Gene end: 4974830
  
Corresponding Affymetrix probe sets: GgaAffx.2234.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000050045
Ensembl peptide - ENSGALP00000060549
Ensembl peptide - ENSGALP00000058672
Ensembl peptide - ENSGALP00000058232
Ensembl peptide - ENSGALP00000057593
NCBI entrez gene - 415718     See in Manteia.
RefSeq - NM_001185147
RefSeq Peptide - NP_001172076
swissprot - A0A1D5PZ24
swissprot - A0A1L1RP33
swissprot - A0A1D5PBB9
swissprot - A0A1D5PX99
swissprot - A0A1L1RIU9
Ensembl - ENSGALG00000041036
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ftoENSDARG00000044216Danio rerio
 FTOENSG00000140718Homo sapiens
 FtoENSMUSG00000055932Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR024366  Alpha-ketoglutarate-dependent dioxygenase FTO, C-terminal
 IPR024367  Alpha-ketoglutarate-dependent dioxygenase FTO, catalytic domain
 IPR032868  Alpha-ketoglutarate-dependent dioxygenase FTO


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001659 temperature homeostasis IEA
 biological_processGO:0006307 DNA dealkylation involved in DNA repair IEA
 biological_processGO:0010883 regulation of lipid storage IEA
 biological_processGO:0035552 oxidative single-stranded DNA demethylation IEA
 biological_processGO:0035553 oxidative single-stranded RNA demethylation IEA
 biological_processGO:0040014 regulation of multicellular organism growth IEA
 biological_processGO:0042245 RNA repair IEA
 biological_processGO:0044065 regulation of respiratory system process IEA
 biological_processGO:0060612 adipose tissue development IEA
 biological_processGO:0070350 regulation of white fat cell proliferation IEA
 biological_processGO:0070989 oxidative demethylation IEA
 biological_processGO:0080111 DNA demethylation IEA
 biological_processGO:0090335 regulation of brown fat cell differentiation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0016607 nuclear speck IEA
 molecular_functionGO:0008198 ferrous iron binding IEA
 molecular_functionGO:0035515 oxidative RNA demethylase activity IEA
 molecular_functionGO:0035516 oxidative DNA demethylase activity IEA
 molecular_functionGO:0043734 DNA-N1-methyladenine dioxygenase activity IEA
 molecular_functionGO:1990931 RNA N6-methyladenosine dioxygenase activity IEA


Pathways (from Reactome)
Pathway description
Reversal of alkylation damage by DNA dioxygenases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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