ENSGALG00000041192


Gallus gallus

Features
Gene ID: ENSGALG00000041192
  
Biological name :IFIH1
  
Synonyms : IFIH1 / interferon-induced helicase C domain-containing protein 1
  
Possible biological names infered from orthology : interferon induced with helicase C domain 1 / Q8R5F7 / Q9BYX4
  
Species: Gallus gallus
  
Chr. number: 7
Strand: 1
Band:
Gene start: 21157246
Gene end: 21184178
  
Corresponding Affymetrix probe sets: Gga.16457.1.S1_s_at (Chicken Array)   GgaAffx.23449.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000047949
NCBI entrez gene - 424185     See in Manteia.
RefSeq - NM_001193638
RefSeq Peptide - NP_001180567
swissprot - A0A1D5P5I0
Ensembl - ENSGALG00000041192
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ifih1ENSDARG00000018553Danio rerio
 IFIH1ENSG00000115267Homo sapiens
 Ifih1ENSMUSG00000026896Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DHX58 / Gallus gallus DExH-box helicase 58 (DHX58), mRNA. / Q96C10* / Q99J87* / DExH-box helicase 58* / Probable ATP-dependent RNA helicase DHX58 *ENSGALG0000002382128
DICER1 / endoribonuclease Dicer / Q9UPY3* / dicer 1, ribonuclease III*ENSGALG0000001099915
FANCM / A0A1D5PRR9 / Fanconi anemia group M protein / Q8BGE5* / Q8IYD8* / Fanconi anemia complementation group M* / Fanconi anemia group M protein homolog *ENSGALG0000003118213


Protein motifs (from Interpro)
Interpro ID Name
 IPR001650  Helicase, C-terminal
 IPR006935  Helicase/UvrB, N-terminal
 IPR011029  Death-like domain superfamily
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR016024  Armadillo-type fold
 IPR021673  RIG-I-like receptor, C-terminal regulatory domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR031964  Caspase recruitment domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009615 response to virus IEA
 biological_processGO:0016925 protein sumoylation IEA
 biological_processGO:0032727 positive regulation of interferon-alpha production IEA
 biological_processGO:0032728 positive regulation of interferon-beta production IEA
 biological_processGO:0035549 positive regulation of interferon-beta secretion IEA
 biological_processGO:0039530 MDA-5 signaling pathway IEA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0051607 defense response to virus IEA
 biological_processGO:0060760 positive regulation of response to cytokine stimulus IEA
 biological_processGO:0071360 cellular response to exogenous dsRNA IEA
 biological_processGO:1902741 positive regulation of interferon-alpha secretion IEA
 biological_processGO:1904469 positive regulation of tumor necrosis factor secretion IEA
 biological_processGO:2000778 positive regulation of interleukin-6 secretion IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003725 double-stranded RNA binding IEA
 molecular_functionGO:0003727 single-stranded RNA binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0043021 ribonucleoprotein complex binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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