ENSGALG00000010999


Gallus gallus

Features
Gene ID: ENSGALG00000010999
  
Biological name :DICER1
  
Synonyms : DICER1 / endoribonuclease Dicer
  
Possible biological names infered from orthology : dicer 1, ribonuclease III / Q9UPY3
  
Species: Gallus gallus
  
Chr. number: 5
Strand: -1
Band:
Gene start: 45907275
Gene end: 45950884
  
Corresponding Affymetrix probe sets: Gga.12004.1.S1_s_at (Chicken Array)   GgaAffx.23420.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000046917
Ensembl peptide - ENSGALP00000054782
Ensembl peptide - ENSGALP00000036777
NCBI entrez gene - 423437     See in Manteia.
RefSeq - NM_001040465
RefSeq Peptide - NP_001035555
swissprot - A0A1D5PPI2
swissprot - F1NJX0
Ensembl - ENSGALG00000010999
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dicer1ENSDARG00000001129Danio rerio
 DICER1ENSG00000100697Homo sapiens
 Dicer1ENSMUSG00000041415Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FANCM / A0A1D5PRR9 / Fanconi anemia group M protein / Q8BGE5* / Q8IYD8* / Fanconi anemia complementation group M* / Fanconi anemia group M protein homolog *ENSGALG0000003118211
IFIH1 / interferon-induced helicase C domain-containing protein 1 / Q8R5F7* / Q9BYX4* / interferon induced with helicase C domain 1*ENSGALG000000411929
DHX58 / Gallus gallus DExH-box helicase 58 (DHX58), mRNA. / Q96C10* / Q99J87* / DExH-box helicase 58* / Probable ATP-dependent RNA helicase DHX58 *ENSGALG000000238218


Protein motifs (from Interpro)
Interpro ID Name
 IPR000999  Ribonuclease III domain
 IPR001650  Helicase, C-terminal
 IPR003100  PAZ domain
 IPR005034  Dicer dimerisation domain
 IPR011545  DEAD/DEAH box helicase domain
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR014720  Double-stranded RNA-binding domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006396 RNA processing IEA
 biological_processGO:0030422 production of siRNA involved in RNA interference IEA
 biological_processGO:0030423 targeting of mRNA for destruction involved in RNA interference IEA
 biological_processGO:0031047 gene silencing by RNA IEA
 biological_processGO:0031054 pre-miRNA processing IEA
 biological_processGO:0033168 conversion of ds siRNA to ss siRNA involved in RNA interference IEA
 biological_processGO:0035087 siRNA loading onto RISC involved in RNA interference IEA
 biological_processGO:0035196 production of miRNAs involved in gene silencing by miRNA IEA
 biological_processGO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA IEA
 biological_processGO:0036404 conversion of ds siRNA to ss siRNA IEA
 biological_processGO:0090501 RNA phosphodiester bond hydrolysis IEA
 biological_processGO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic IEA
 cellular_componentGO:0035068 micro-ribonucleoprotein complex IEA
 cellular_componentGO:0070062 extracellular exosome IEA
 cellular_componentGO:0070578 RISC-loading complex IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003725 double-stranded RNA binding IEA
 molecular_functionGO:0004521 endoribonuclease activity IEA
 molecular_functionGO:0004525 ribonuclease III activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016891 endoribonuclease activity, producing 5"-phosphomonoesters IEA
 molecular_functionGO:0019904 protein domain specific binding IEA
 molecular_functionGO:0035197 siRNA binding IEA
 molecular_functionGO:0070883 pre-miRNA binding IEA


Pathways (from Reactome)
Pathway description
MicroRNA (miRNA) biogenesis
Small interfering RNA (siRNA) biogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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