ENSGALG00000041299


Gallus gallus

Features
Gene ID: ENSGALG00000041299
  
Biological name :E2F8
  
Synonyms : E2F8 / E2F transcription factor 8
  
Possible biological names infered from orthology : A0AVK6 / Q58FA4 / Transcription factor E2F8
  
Species: Gallus gallus
  
Chr. number: 5
Strand: -1
Band:
Gene start: 1667059
Gene end: 1676014
  
Corresponding Affymetrix probe sets: Gga.10825.1.S1_s_at (Chicken Array)   Gga.16057.1.S1_s_at (Chicken Array)   GgaAffx.2488.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000053725
Ensembl peptide - ENSGALP00000055120
NCBI entrez gene - 422978     See in Manteia.
RefSeq - XM_015286250
RefSeq - XM_015286249
swissprot - A0A1D5PQF7
swissprot - A0A1D5PLK8
Ensembl - ENSGALG00000041299
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 e2f8ENSDARG00000057323Danio rerio
 E2F8ENSG00000129173Homo sapiens
 E2f8ENSMUSG00000046179Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
E2F7 / E2F transcription factor 7 / Q6S7F2* / Q96AV8* / Mus musculus E2F transcription factor 7 (E2f7), transcript variant 2, mRNA.*ENSGALG0000003134030


Protein motifs (from Interpro)
Interpro ID Name
 IPR003316  E2F/DP family, winged-helix DNA-binding domain
 IPR011991  ArsR-like helix-turn-helix domain
 IPR015633  E2F Family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001890 placenta development IEA
 biological_processGO:0002040 sprouting angiogenesis IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0008283 cell proliferation IEA
 biological_processGO:0032466 negative regulation of cytokinesis IEA
 biological_processGO:0032877 positive regulation of DNA endoreduplication IEA
 biological_processGO:0033301 cell cycle comprising mitosis without cytokinesis IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0060707 trophoblast giant cell differentiation IEA
 biological_processGO:0060718 chorionic trophoblast cell differentiation IEA
 biological_processGO:0070365 hepatocyte differentiation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005667 transcription factor complex IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001047 core promoter binding IEA
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003714 transcription corepressor activity IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA


Pathways (from Reactome)
Pathway description
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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