ENSGALG00000041454


Gallus gallus

Features
Gene ID: ENSGALG00000041454
  
Biological name :DNMT3A
  
Synonyms : DNA (cytosine-5)-methyltransferase 3A / DNMT3A
  
Possible biological names infered from orthology : DNA methyltransferase 3 alpha / O88508 / Q9Y6K1
  
Species: Gallus gallus
  
Chr. number: 3
Strand: -1
Band:
Gene start: 105053765
Gene end: 105065491
  
Corresponding Affymetrix probe sets: Gga.6002.1.S1_a_at (Chicken Array)   GgaAffx.10574.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000043719
Ensembl peptide - ENSGALP00000063087
Ensembl peptide - ENSGALP00000048074
NCBI entrez gene - 421991     See in Manteia.
RefSeq - NM_001024832
RefSeq Peptide - NP_001020003
swissprot - A0A1L1RW76
swissprot - A0A1D5P5V1
swissprot - A0A1D5NTR2
Ensembl - ENSGALG00000041454
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dnmt3aaENSDARG00000005394Danio rerio
 dnmt3abENSDARG00000015566Danio rerio
 DNMT3AENSG00000119772Homo sapiens
 Dnmt3aENSMUSG00000020661Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DNMT3B / DNA methyltransferase 3 beta / Dnmt3c* / Q9UBC3* / O88509* / DNA (cytosine-5)-methyltransferase 3B *ENSGALG0000004146142


Protein motifs (from Interpro)
Interpro ID Name
 IPR000313  PWWP domain
 IPR001525  C-5 cytosine methyltransferase
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR018117  DNA methylase, C-5 cytosine-specific, active site
 IPR025766  ADD domain
 IPR029063  S-adenosyl-L-methionine-dependent methyltransferase
 IPR030487  DNA (cytosine-5)-methyltransferase 3A


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006306 DNA methylation IEA
 biological_processGO:0006346 methylation-dependent chromatin silencing IEA
 biological_processGO:0006349 regulation of gene expression by genetic imprinting IEA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0032259 methylation IEA
 biological_processGO:0043045 DNA methylation involved in embryo development IEA
 biological_processGO:0043046 DNA methylation involved in gamete generation IEA
 biological_processGO:0071230 cellular response to amino acid stimulus IEA
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0000791 euchromatin IEA
 cellular_componentGO:0000792 heterochromatin IEA
 cellular_componentGO:0001741 XY body IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005720 nuclear heterochromatin IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016363 nuclear matrix IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003886 DNA (cytosine-5-)-methyltransferase activity IEA
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0009008 DNA-methyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
PRC2 methylates histones and DNA
RMTs methylate histone arginines


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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