ENSGALG00000041708


Gallus gallus

Features
Gene ID: ENSGALG00000041708
  
Biological name :WNT4
  
Synonyms : P49337 / Protein Wnt-4 / WNT4
  
Possible biological names infered from orthology : P22724 / P56705 / wingless-type MMTV integration site family, member 4 / Wnt family member 4
  
Species: Gallus gallus
  
Chr. number: 21
Strand: 1
Band:
Gene start: 6322863
Gene end: 6334599
  
Corresponding Affymetrix probe sets: Gga.305.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000046583
NCBI entrez gene - 395561     See in Manteia.
RefSeq - NM_204783
RefSeq Peptide - NP_990114
swissprot - P49337
Ensembl - ENSGALG00000041708
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 wnt4aENSDARG00000071208Danio rerio
 WNT4ENSG00000162552Homo sapiens
 Wnt4ENSMUSG00000036856Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
WNT2B / O70283* / Q93097* / Wnt family member 2B* / wingless-type MMTV integration site family, member 2B*ENSGALG0000003419648
WNT5B / protein Wnt-5b precursor / Q9H1J7* / P22726* / Wnt family member 5B* / wingless-type MMTV integration site family, member 5B*ENSGALG0000001299848
WNT5A / Wnt family member 5A / P22725* / P41221* / wingless-type MMTV integration site family, member 5A*ENSGALG0000003416848
WNT2 / Wnt family member 2 / P09544* / P21552* / wingless-type MMTV integration site family, member 2*ENSGALG0000003017347
WNT7B / Q3L254 / Protein Wnt-7b / P56706* / P28047* / Wnt family member 7B* / wingless-type MMTV integration site family, member 7B*ENSGALG0000003625546
WNT3 / Wnt family member 3 / P17553* / P56703* / wingless-type MMTV integration site family, member 3*ENSGALG0000000107945
WNT7A / Wnt family member 7A / O00755* / P24383* / wingless-type MMTV integration site family, member 7A*ENSGALG0000000512345
WNT3A / Q2LMP1 / Protein Wnt-3a / P56704* / P27467* / Wnt family member 3A* / wingless-type MMTV integration site family, member 3A*ENSGALG0000004265744
WNT6 / protein Wnt-6 / Q9Y6F9* / P22727* / Wnt family member 6* / wingless-type MMTV integration site family, member 6*ENSGALG0000001135842
WNT11 / P49339 / Protein Wnt-11 / P48615* / O96014* / Wnt family member 11* / wingless-type MMTV integration site family, member 11*ENSGALG0000000083940
WNT16 / Wnt family member 16 / Q9QYS1* / Q9UBV4* / wingless-type MMTV integration site family, member 16*ENSGALG0000002806940
WNT11BENSGALG0000000440139


Protein motifs (from Interpro)
Interpro ID Name
 IPR005817  Wnt
 IPR009142  Wnt-4 protein
 IPR018161  Wnt protein, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001656 metanephros development IEA
 biological_processGO:0001658 branching involved in ureteric bud morphogenesis IEA
 biological_processGO:0001822 kidney development IEA
 biological_processGO:0001823 mesonephros development IEA
 biological_processGO:0001837 epithelial to mesenchymal transition IEA
 biological_processGO:0001838 embryonic epithelial tube formation IEA
 biological_processGO:0001889 liver development IEA
 biological_processGO:0006702 androgen biosynthetic process IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007276 gamete generation IEA
 biological_processGO:0007548 sex differentiation IEA
 biological_processGO:0008584 male gonad development IEA
 biological_processGO:0008585 female gonad development IEA
 biological_processGO:0009267 cellular response to starvation IEA
 biological_processGO:0010629 negative regulation of gene expression IEA
 biological_processGO:0010894 negative regulation of steroid biosynthetic process IEA
 biological_processGO:0014858 positive regulation of skeletal muscle cell proliferation IMP
 biological_processGO:0016055 Wnt signaling pathway IBA
 biological_processGO:0022407 regulation of cell-cell adhesion IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030182 neuron differentiation IBA
 biological_processGO:0030237 female sex determination IEA
 biological_processGO:0030325 adrenal gland development IEA
 biological_processGO:0030336 negative regulation of cell migration IEA
 biological_processGO:0030501 positive regulation of bone mineralization IEA
 biological_processGO:0032349 positive regulation of aldosterone biosynthetic process IEA
 biological_processGO:0032967 positive regulation of collagen biosynthetic process IEA
 biological_processGO:0033077 T cell differentiation in thymus IEA
 biological_processGO:0033080 immature T cell proliferation in thymus IEA
 biological_processGO:0035239 tube morphogenesis IEA
 biological_processGO:0035567 non-canonical Wnt signaling pathway IEA
 biological_processGO:0038030 non-canonical Wnt signaling pathway via MAPK cascade IEA
 biological_processGO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway IEA
 biological_processGO:0042445 hormone metabolic process IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0045165 cell fate commitment IEA
 biological_processGO:0045596 negative regulation of cell differentiation IEA
 biological_processGO:0045669 positive regulation of osteoblast differentiation IEA
 biological_processGO:0045836 positive regulation of meiotic nuclear division IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0048599 oocyte development IEA
 biological_processGO:0048754 branching morphogenesis of an epithelial tube IEA
 biological_processGO:0048856 anatomical structure development IEA
 biological_processGO:0051145 smooth muscle cell differentiation IEA
 biological_processGO:0051496 positive regulation of stress fiber assembly IEA
 biological_processGO:0051894 positive regulation of focal adhesion assembly IEA
 biological_processGO:0060070 canonical Wnt signaling pathway IEA
 biological_processGO:0060126 somatotropin secreting cell differentiation IEA
 biological_processGO:0060129 thyroid-stimulating hormone-secreting cell differentiation IEA
 biological_processGO:0060231 mesenchymal to epithelial transition IEA
 biological_processGO:0060748 tertiary branching involved in mammary gland duct morphogenesis IEA
 biological_processGO:0060993 kidney morphogenesis IEA
 biological_processGO:0061036 positive regulation of cartilage development TAS
 biological_processGO:0061045 negative regulation of wound healing IEA
 biological_processGO:0061180 mammary gland epithelium development IEA
 biological_processGO:0061184 positive regulation of dermatome development IEA
 biological_processGO:0061205 paramesonephric duct development IEA
 biological_processGO:0061369 negative regulation of testicular blood vessel morphogenesis IEA
 biological_processGO:0071560 cellular response to transforming growth factor beta stimulus IEA
 biological_processGO:0072006 nephron development IEA
 biological_processGO:0072033 renal vesicle formation IEA
 biological_processGO:0072034 renal vesicle induction IEA
 biological_processGO:0072164 mesonephric tubule development IEA
 biological_processGO:0072174 metanephric tubule formation IEA
 biological_processGO:0072210 metanephric nephron development IEA
 biological_processGO:0072273 metanephric nephron morphogenesis IEA
 biological_processGO:0072659 protein localization to plasma membrane IEA
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway IEA
 biological_processGO:0090263 positive regulation of canonical Wnt signaling pathway IEA
 biological_processGO:1902811 positive regulation of skeletal muscle fiber differentiation IMP
 biological_processGO:2000019 negative regulation of male gonad development IEA
 biological_processGO:2000066 positive regulation of cortisol biosynthetic process IEA
 biological_processGO:2000225 negative regulation of testosterone biosynthetic process IEA
 biological_processGO:2001234 negative regulation of apoptotic signaling pathway IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0009986 cell surface IEA
 molecular_functionGO:0003714 transcription corepressor activity IEA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0005109 frizzled binding IEA


Pathways (from Reactome)
Pathway description
WNT ligand biogenesis and trafficking


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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