ENSGALG00000041722


Gallus gallus

Features
Gene ID: ENSGALG00000041722
  
Biological name :STX1A
  
Synonyms : STX1A / syntaxin 1A
  
Possible biological names infered from orthology : O35526 / Q16623 / syntaxin 1A (brain)
  
Species: Gallus gallus
  
Chr. number: 19
Strand: -1
Band:
Gene start: 94035
Gene end: 139377
  
Corresponding Affymetrix probe sets: Gga.16839.1.S1_at (Chicken Array)   GgaAffx.24445.1.S1_s_at (Chicken Array)   GgaAffx.25299.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000044709
Ensembl peptide - ENSGALP00000056136
Ensembl peptide - ENSGALP00000049478
NCBI entrez gene - 100857565     See in Manteia.
RefSeq - XM_015295897
RefSeq - XM_015295898
swissprot - A0A1D5PT93
swissprot - A0A1D5P9S0
swissprot - A0A1D5NWG9
Ensembl - ENSGALG00000041722
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 stx1aENSDARG00000058994Danio rerio
 STX1AENSG00000106089Homo sapiens
 Stx1aENSMUSG00000007207Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
STX2 / syntaxin 2 / P32856*ENSGALG0000000253666
STX11* / O75558* / syntaxin 11*ENSGALG0000001167333
STX19 / syntaxin 19 / Q8N4C7* / Q8R1Q0*ENSGALG0000001541328


Protein motifs (from Interpro)
Interpro ID Name
 IPR000727  Target SNARE coiled-coil homology domain
 IPR006011  Syntaxin, N-terminal domain
 IPR006012  Syntaxin/epimorphin, conserved site
 IPR010989  SNARE
 IPR028669  Syntaxin 1A


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001956 positive regulation of neurotransmitter secretion IEA
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0010807 regulation of synaptic vesicle priming IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0017156 calcium ion regulated exocytosis IEA
 biological_processGO:0017157 regulation of exocytosis IEA
 biological_processGO:0032940 secretion by cell IEA
 biological_processGO:0061025 membrane fusion IEA
 biological_processGO:2000463 positive regulation of excitatory postsynaptic potential IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0008021 synaptic vesicle IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0030672 synaptic vesicle membrane IEA
 cellular_componentGO:0031201 SNARE complex IEA
 cellular_componentGO:0031965 nuclear membrane IEA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex IEA
 molecular_functionGO:0000149 SNARE binding IEA
 molecular_functionGO:0005484 SNAP receptor activity IEA
 molecular_functionGO:0019855 calcium channel inhibitor activity IEA
 molecular_functionGO:0019869 chloride channel inhibitor activity IEA
 molecular_functionGO:0019900 kinase binding IEA


Pathways (from Reactome)
Pathway description
Norepinephrine Neurotransmitter Release Cycle
Glutamate Neurotransmitter Release Cycle
Acetylcholine Neurotransmitter Release Cycle
Other interleukin signaling
LGI-ADAM interactions
GABA synthesis, release, reuptake and degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000009003 SNAP25 / P60878 / Synaptosomal-associated protein 25 / P60880* / P60879* / synaptosome associated protein 25* / Mus musculus synaptosomal-associated protein 25 (Snap25), transcript variant 4, mRNA.*  / complex






 

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