ENSGALG00000041988


Gallus gallus

Features
Gene ID: ENSGALG00000041988
  
Biological name :SIK1
  
Synonyms : serine/threonine-protein kinase SIK2 / SIK1
  
Possible biological names infered from orthology : P57059 / Q60670 / salt inducible kinase 1 / salt inducible kinase 1B (putative) / Serine/threonine-protein kinase SIK1 / SIK1B
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 109907383
Gene end: 109920133
  
Corresponding Affymetrix probe sets: Gga.2833.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000053588
NCBI entrez gene - 395417     See in Manteia.
RefSeq - NM_204682
RefSeq Peptide - NP_990013
swissprot - A0A1D5PL73
Ensembl - ENSGALG00000041988
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sik1ENSDARG00000058606Danio rerio
 SIK1ENSG00000142178Homo sapiens
 SIK1BENSG00000275993Homo sapiens
 Sik1ENSMUSG00000024042Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SIK2 / salt inducible kinase 2 / Q9H0K1*ENSGALG0000003687347
SIK3 / SIK family kinase 3ENSGALG0000000714435
MARK3 / microtubule affinity regulating kinase 3 / P27448* / Q03141* / MAP/microtubule affinity-regulating kinase 3 *ENSGALG0000001150529
MARK1 / microtubule affinity regulating kinase 1 / Q8VHJ5* / Q9P0L2* / Serine/threonine-protein kinase MARK1 *ENSGALG0000000948328
SNRK / SNF related kinase / Q8VDU5* / Q9NRH2* / Mus musculus SNF related kinase (Snrk), transcript variant 5, mRNA.*ENSGALG0000003992023
ENSGALG0000002604319
NIM1KZ / NIM1K* / Q8IY84* / Q8BHI9* / NIM1 serine/threonine protein kinase* / Serine/threonine-protein kinase NIM1 *ENSGALG0000001486116


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR015940  Ubiquitin-associated domain
 IPR017090  Serine/threonine-protein kinase, SIK1/2
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007346 regulation of mitotic cell cycle IEA
 biological_processGO:0010830 regulation of myotube differentiation IEA
 biological_processGO:0010868 negative regulation of triglyceride biosynthetic process IEA
 biological_processGO:0032792 negative regulation of CREB transcription factor activity IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0043153 entrainment of circadian clock by photoperiod IEA
 biological_processGO:0043276 anoikis IEA
 biological_processGO:0045595 regulation of cell differentiation IEA
 biological_processGO:0045721 negative regulation of gluconeogenesis IEA
 biological_processGO:0055007 cardiac muscle cell differentiation IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008140 cAMP response element binding protein binding IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0042826 histone deacetylase binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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