ENSG00000275993


Homo sapiens

Features
Gene ID: ENSG00000275993
  
Biological name :SIK1B
  
Synonyms : salt inducible kinase 1B (putative) / SIK1B
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 21
Strand: 1
Band: p12
Gene start: 6111134
Gene end: 6123739
  
Corresponding Affymetrix probe sets: 208078_s_at (Human Genome U133 Plus 2.0 Array)   232470_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000482829
NCBI entrez gene - 102724428     See in Manteia.
RefSeq - NM_001320643
RefSeq - XM_017028208
RefSeq Peptide - NP_001307572
swissprot - A0A0B4J2F2
Ensembl - ENSG00000275993
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sik1ENSDARG00000058606Danio rerio
 SIK1ENSGALG00000041988Gallus gallus
 Sik1ENSMUSG00000024042Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SIK1 / P57059 / salt inducible kinase 1ENSG00000142178100
SIK2 / Q9H0K1 / salt inducible kinase 2ENSG0000017014549
SIK3 / SIK family kinase 3ENSG0000016058438
MARK4 / Q96L34 / microtubule affinity regulating kinase 4ENSG0000000704729
MARK3 / P27448 / microtubule affinity regulating kinase 3ENSG0000007541329
MARK1 / Q9P0L2 / microtubule affinity regulating kinase 1ENSG0000011614128
MARK2 / Q7KZI7 / microtubule affinity regulating kinase 2ENSG0000007251828
SNRK / Q9NRH2 / SNF related kinaseENSG0000016378822
NIM1K / Q8IY84 / NIM1 serine/threonine protein kinaseENSG0000017745317


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR015940  Ubiquitin-associated domain
 IPR017090  Serine/threonine-protein kinase, SIK1/2
 IPR017441  Protein kinase, ATP binding site
 IPR034672  Salt-Inducible kinase, catalytic domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IBA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0032870 cellular response to hormone stimulus IBA
 biological_processGO:0035556 intracellular signal transduction IBA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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