ENSGALG00000042986


Gallus gallus

Features
Gene ID: ENSGALG00000042986
  
Biological name :RNASEL
  
Synonyms : 2-5A-dependent ribonuclease / RNASEL
  
Possible biological names infered from orthology : Q05823 / Q05921 / ribonuclease L / ribonuclease L (2, 5-oligoisoadenylate synthetase-dependent)
  
Species: Gallus gallus
  
Chr. number: 8
Strand: 1
Band:
Gene start: 5622614
Gene end: 5628060
  
Corresponding Affymetrix probe sets: GgaAffx.2291.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000050610
NCBI entrez gene - 424410     See in Manteia.
RefSeq - XM_015290279
RefSeq - NM_001031267
RefSeq - XM_015290276
RefSeq - XM_015290278
RefSeq Peptide - NP_001026438
swissprot - A0A1D5PCW9
Ensembl - ENSGALG00000042986
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q05823ENSG00000135828Homo sapiens
 Q05921ENSMUSG00000066800Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ANKHD1 / Q8IWZ3* / ANKHD1-EIF4EBP3* / ANKHD1-EIF4EBP3 readthrough* / ankyrin repeat and KH domain containing 1*ENSGALG0000000109918
ANKRD17 / ankyrin repeat domain 17 / O75179* / Q99NH0* / Ankyrin repeat domain-containing protein 17 *ENSGALG0000001164218
ANKRD50 / ankyrin repeat domain 50 / Q9ULJ7*ENSGALG0000001183115
ANKS6 / ankyrin repeat and sterile alpha motif domain containing 6 / Q68DC2* / Q6GQX6* / Ankyrin repeat and SAM domain-containing protein 6 *ENSGALG0000001319614
TANC1 / tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 / Q0VGY8* / Q9C0D5* / Protein TANC1 *ENSGALG0000001257014
TANC2* / A2A690* / Q9HCD6* / Protein TANC2 * / tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2*ENSGALG0000000047813
ANKRD29 / ankyrin repeat domain 29 / Q8N6D5*ENSGALG000000150349
KIDINS220 / kinase D interacting substrate 220 / Q9ULH0*ENSGALG000000164093
TANC2* / A2A690* / Q9HCD6* / Protein TANC2 * / tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2*ENSGALG000000458050


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR002110  Ankyrin repeat
 IPR010513  KEN domain
 IPR011009  Protein kinase-like domain superfamily
 IPR020683  Ankyrin repeat-containing domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0043488 regulation of mRNA stability IEA
 biological_processGO:0045071 negative regulation of viral genome replication IEA
 biological_processGO:0045444 fat cell differentiation IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0051607 defense response to virus IEA
 biological_processGO:0090501 RNA phosphodiester bond hydrolysis IEA
 biological_processGO:2001275 positive regulation of glucose import in response to insulin stimulus IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0004540 ribonuclease activity IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0043021 ribonucleoprotein complex binding IEA


Pathways (from Reactome)
Pathway description
Interferon alpha/beta signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000042986 RNASEL / 2-5A-dependent ribonuclease / Q05921* / Q05823* / ribonuclease L* / ribonuclease L (2, 5-oligoisoadenylate synthetase-dependent)*  / complex






 

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