ENSMUSG00000003437


Mus musculus

Features
Gene ID: ENSMUSG00000003437
  
Biological name :Paf1
  
Synonyms : Paf1 / Q8K2T8 / RNA polymerase II-associated factor 1 homolog
  
Possible biological names infered from orthology : PAF1 homolog, Paf1/RNA polymerase II complex component / Q8N7H5
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: B1
Gene start: 28392951
Gene end: 28399388
  
Corresponding Affymetrix probe sets: 10551496 (MoGene1.0st)   1416874_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000003529
NCBI entrez gene - 54624     See in Manteia.
MGI - MGI:1923988
RefSeq - NM_019458
RefSeq Peptide - NP_062331
swissprot - Q8K2T8
Ensembl - ENSMUSG00000003437
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 paf1ENSDARG00000098432Danio rerio
 PAF1ENSGALG00000037879Gallus gallus
 PAF1ENSG00000006712Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007133  RNA polymerase II associated factor Paf1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IMP
 biological_processGO:0001711 endodermal cell fate commitment IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006368 transcription elongation from RNA polymerase II promoter IEA
 biological_processGO:0006378 mRNA polyadenylation IEA
 biological_processGO:0010390 histone monoubiquitination IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0016570 histone modification IEA
 biological_processGO:0016584 nucleosome positioning IEA
 biological_processGO:0019827 stem cell population maintenance IMP
 biological_processGO:0031062 positive regulation of histone methylation IEA
 biological_processGO:0031442 positive regulation of mRNA 3"-end processing IEA
 biological_processGO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter IEA
 biological_processGO:0033523 histone H2B ubiquitination IEA
 biological_processGO:0034504 protein localization to nucleus IEA
 biological_processGO:0045638 negative regulation of myeloid cell differentiation IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0071222 cellular response to lipopolysaccharide IDA
 biological_processGO:1902808 positive regulation of cell cycle G1/S phase transition IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016593 Cdc73/Paf1 complex ISO
 cellular_componentGO:0030054 cell junction IEA
 molecular_functionGO:0000993 RNA polymerase II core binding IEA
 molecular_functionGO:0003682 chromatin binding IDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Formation of RNA Pol II elongation complex
RNA Polymerase II Pre-transcription Events
RNA Polymerase II Transcription Elongation
E3 ubiquitin ligases ubiquitinate target proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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