ENSMUSG00000003746


Mus musculus

Features
Gene ID: ENSMUSG00000003746
  
Biological name :Man1a
  
Synonyms : Man1a / mannosidase 1, alpha / P45700
  
Possible biological names infered from orthology : MAN1A1 / mannosidase alpha class 1A member 1 / P33908
  
Species: Mus musculus
  
Chr. number: 10
Strand: -1
Band: B3
Gene start: 53904785
Gene end: 54076609
  
Corresponding Affymetrix probe sets: 10369154 (MoGene1.0st)   1417110_at (Mouse Genome 430 2.0 Array)   1417111_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000151328
Ensembl peptide - ENSMUSP00000151568
Ensembl peptide - ENSMUSP00000003843
Ensembl peptide - ENSMUSP00000101110
NCBI entrez gene - 17155     See in Manteia.
MGI - MGI:104677
RefSeq - XM_006512568
RefSeq - XM_006512569
RefSeq - XM_011243136
RefSeq - NM_008548
RefSeq Peptide - NP_032574
swissprot - P45700
swissprot - A0A1W2P6N0
swissprot - A0A1W2P788
swissprot - Q544T7
Ensembl - ENSMUSG00000003746
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 man1a1ENSDARG00000005652Danio rerio
 MAN1A1ENSGALG00000014878Gallus gallus
 MAN1A1ENSG00000111885Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Man1a2 / P39098 / Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB / O60476* / mannosidase alpha class 1A member 2*ENSMUSG0000000876361
Man1c1 / mannosidase alpha class 1C member 1 / Q9NR34*ENSMUSG0000003730651
A2AJ15 / Man1b1 / Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase / Q9UKM7* / mannosidase alpha class 1B member 1*ENSMUSG0000003664631


Protein motifs (from Interpro)
Interpro ID Name
 IPR001382  Glycoside hydrolase family 47
 IPR036026  Seven-hairpin glycosidases


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006486 protein glycosylation IEA
 biological_processGO:0006491 N-glycan processing IBA
 biological_processGO:0008152 metabolic process IEA
 cellular_componentGO:0000139 Golgi membrane IDA
 cellular_componentGO:0005783 endoplasmic reticulum IBA
 cellular_componentGO:0005793 endoplasmic reticulum-Golgi intermediate compartment ISO
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016798 hydrolase activity, acting on glycosyl bonds IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Intra-Golgi traffic
Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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