ENSMUSG00000037306


Mus musculus

Features
Gene ID: ENSMUSG00000037306
  
Biological name :Man1c1
  
Synonyms : Man1c1 / mannosidase alpha class 1C member 1
  
Possible biological names infered from orthology : Q9NR34
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: D3
Gene start: 134561690
Gene end: 134704290
  
Corresponding Affymetrix probe sets: 10517287 (MoGene1.0st)   1436193_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000037949
Ensembl peptide - ENSMUSP00000050979
NCBI entrez gene - 230815     See in Manteia.
MGI - MGI:2446214
RefSeq - XM_011250232
RefSeq - NM_207237
RefSeq - XM_006538757
RefSeq Peptide - NP_997120
swissprot - Q6NXK9
Ensembl - ENSMUSG00000037306
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MAN1C1ENSDARG00000067912Danio rerio
 MAN1C1ENSGALG00000001038Gallus gallus
 MAN1C1ENSG00000117643Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Man1a / P45700 / mannosidase 1, alpha / P33908* / MAN1A1* / mannosidase alpha class 1A member 1*ENSMUSG0000000374654
Man1a2 / P39098 / Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB / O60476* / mannosidase alpha class 1A member 2*ENSMUSG0000000876351
A2AJ15 / Man1b1 / Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase / Q9UKM7* / mannosidase alpha class 1B member 1*ENSMUSG0000003664630


Protein motifs (from Interpro)
Interpro ID Name
 IPR001382  Glycoside hydrolase family 47
 IPR036026  Seven-hairpin glycosidases


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006013 mannose metabolic process ISO
 biological_processGO:0006491 N-glycan processing IBA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0030166 proteoglycan biosynthetic process ISO
 cellular_componentGO:0000139 Golgi membrane IBA
 cellular_componentGO:0005783 endoplasmic reticulum IBA
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity IBA
 molecular_functionGO:0005509 calcium ion binding ISO
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016798 hydrolase activity, acting on glycosyl bonds IEA


Pathways (from Reactome)
Pathway description
Intra-Golgi traffic
Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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