ENSMUSG00000004651


Mus musculus

Features
Gene ID: ENSMUSG00000004651
  
Biological name :Tyr
  
Synonyms : P11344 / Tyr / tyrosinase
  
Possible biological names infered from orthology : P14679
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: D3
Gene start: 87424771
Gene end: 87493512
  
Corresponding Affymetrix probe sets: 10565422 (MoGene1.0st)   1417717_a_at (Mouse Genome 430 2.0 Array)   1448821_at (Mouse Genome 430 2.0 Array)   1456095_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000004770
Ensembl peptide - ENSMUSP00000146757
NCBI entrez gene - 22173     See in Manteia.
MGI - MGI:98880
RefSeq - NM_001317397
RefSeq - NM_011661
RefSeq Peptide - NP_001304326
RefSeq Peptide - NP_035791
swissprot - Q91XK0
swissprot - P11344
swissprot - A0A140LIB9
Ensembl - ENSMUSG00000004651
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tyrENSDARG00000039077Danio rerio
 TYRENSGALG00000017237Gallus gallus
 TYRENSG00000077498Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Dct / P29812 / L-dopachrome tautomerase / P40126* / dopachrome tautomerase*ENSMUSG0000002212938
Tyrp1 / P07147 / tyrosinase-related protein 1 / P17643*ENSMUSG0000000599438


Protein motifs (from Interpro)
Interpro ID Name
 IPR002227  Tyrosinase copper-binding domain
 IPR008922  Uncharacterised domain, di-copper centre


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0008283 cell proliferation IMP
 biological_processGO:0009411 response to UV IEA
 biological_processGO:0033280 response to vitamin D IEA
 biological_processGO:0042438 melanin biosynthetic process ISO
 biological_processGO:0043473 pigmentation IEA
 biological_processGO:0048538 thymus development IMP
 biological_processGO:0051591 response to cAMP IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane TAS
 cellular_componentGO:0033162 melanosome membrane IEA
 cellular_componentGO:0042470 melanosome ISO
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0004497 monooxygenase activity IEA
 molecular_functionGO:0004503 monophenol monooxygenase activity ISO
 molecular_functionGO:0005507 copper ion binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IDA


Pathways (from Reactome)
Pathway description
Melanin biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000358 abnormal cell content/ morphology "structural anomalies of the minute protoplasmic masses that make up organized tissues and which are the fundamental structural and functional units of living organisms" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Rfngtm2.1Tfv/Rfngtm2.1Tfv
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac

 MP:0000371 diluted coat color "a coat color that appears lighter in intensity or paler than normal" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Chrnb2tm1Mdb/Chrnb2tm1Mdb,Chrnb4tm1Mdb/Chrnb4tm1Mdb
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

Allelic Composition: a/a,Tyrc-i/Tyrc-i
Genetic Background: involves: STOCK Tyrc-r

Allelic Composition: Tyrc-h/Tyrc-25H
Genetic Background: STOCK Tyrc-h/Tyrc-25H

Allelic Composition: Tyrc-112K/Tyrc-ch
Genetic Background: involves: 101/R1 * C3Hf/R1 * St.2A

Allelic Composition: Tyrc-ch/Tyrc-ch
Genetic Background: involves: C57BL/6

Allelic Composition: Tyrc-h/Tyrc-h
Genetic Background: involves: C57BL/6

Allelic Composition: Tyrc-p/Tyrc-p
Genetic Background: involves: C57BL/6

Allelic Composition: Tyrc-36FrS/Tyrc-36FrS
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-36FrS/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-8FrS/Tyrc-8FrS
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-8FrS/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-h/Tyrc-h
Genetic Background: involves: AKR/J * DBA/2J

Allelic Composition: Tyrc-h/Tyrc
Genetic Background: involves: AKR/J * DBA/2J

Allelic Composition: Tyrc-ch/Del(7)Tyrc-3H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Tyrc-ch/Del(7)Tyrc-6H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Tyrm3Btlr/Tyrm3Btlr
Genetic Background: involves: C57BL/6J

Allelic Composition: Tyrc-ch62H/Tyrc-ch62H
Genetic Background: involves: BALB/c * C3H/HeH

Allelic Composition: Tyrc/Tyrc-ch62H
Genetic Background: involves: BALB/c * C3H/HeH

Allelic Composition: Tyrc-ch83R/Tyrc-ch83R
Genetic Background: involves: 101/Rl * C3H/Rl * T-stock

Allelic Composition: Tyrc/Tyrc-ch83R
Genetic Background: involves: 101/Rl * C3H/Rl * T-stock

Allelic Composition: Tyrc-em/Tyrc-em
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Tyrc-ch37H/Tyrc-ch37H
Genetic Background: involves: 101/H

Allelic Composition: Tyrc-ch38H/Tyrc-ch38H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Tyrc-ch/Tyrc-ch38H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Tyrc-40H/Tyrc-ch
Genetic Background: involves: C3H/HeH

Allelic Composition: Tyrc-42H/Tyrc-ch
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Tyrc-ch54H/Tyrc-ch54H
Genetic Background: involves: 101/H

Allelic Composition: Tyrc-h/Tyrc-h
Genetic Background: B6.Cg-Tyrc-h/J

Allelic Composition: Tyrm4Btlr/Tyrm4Btlr
Genetic Background: C57BL/6J-Tyrm4Btlr

Allelic Composition: Tyrm5Btlr/Tyrm5Btlr
Genetic Background: C57BL/6J-Tyrm5Btlr

Allelic Composition: A/?,Tyrem1Ove/Tyrem1Ove
Genetic Background: involves: C57BL/6 * FVB

Allelic Composition: A/?,Tyrc/Tyrem1Ove
Genetic Background: involves: C57BL/6 * FVB

Allelic Composition: a/a,Tyrem2Ove/Tyrem2Ove
Genetic Background: involves: C57BL/6 * FVB

Allelic Composition: Tyrem3Ove/Tyrem3Ove
Genetic Background: involves: C57BL/6 * FVB

Allelic Composition: a/a,Tyrem4Ove/Tyrem4Ove
Genetic Background: involves: C57BL/6 * FVB

Allelic Composition: a/a,Tyrc/Tyrem4Ove
Genetic Background: involves: C57BL/6 * FVB

Allelic Composition: Tyrem5Ove/Tyrem5Ove
Genetic Background: involves: C57BL/6 * FVB

Allelic Composition: Tyrem6Ove/Tyrem6Ove
Genetic Background: involves: C57BL/6 * FVB

Allelic Composition: A/?,Tyrc/Tyrem6Ove
Genetic Background: involves: C57BL/6 * FVB

Allelic Composition: A/?,Tyrem7Ove/Tyrem7Ove
Genetic Background: involves: C57BL/6 * FVB

Allelic Composition: A/?,Tyrc/Tyrem7Ove
Genetic Background: involves: C57BL/6 * FVB

Allelic Composition: A/?,Tyrem8Ove/Tyrem8Ove
Genetic Background: involves: C57BL/6 * FVB

Allelic Composition: Tyrc/Tyrem8Ove
Genetic Background: involves: C57BL/6 * FVB

Allelic Composition: A/?,Tyrem9Ove/Tyrem9Ove
Genetic Background: involves: C57BL/6 * FVB

Allelic Composition: a/a,Tyrc/Tyrem9Ove
Genetic Background: involves: C57BL/6 * FVB

Allelic Composition: A/?,Tyrem12Ove/Tyrem12Ove
Genetic Background: involves: C57BL/6 * FVB

Allelic Composition: a/a,Tyrem14Ove/Tyrem14Ove
Genetic Background: involves: C57BL/6 * FVB

Allelic Composition: a/a,Tyrc/Tyrem14Ove
Genetic Background: involves: C57BL/6 * FVB

Allelic Composition: A/a,Tyrem15Ove/Tyrem15Ove
Genetic Background: involves: C57BL/6 * FVB

Allelic Composition: a/a,Tyrc/Tyrem2Ove
Genetic Background: involves: C57BL/6 * FVB

Allelic Composition: A/?,Tyrc/Tyrem12Ove
Genetic Background: involves: C57BL/6 * FVB

 MP:0000372 irregular coat pigmentation "uneven coloration of the hair" [J:65030]
Show

Allelic Composition: Tyrc-m/Tyrc-m
Genetic Background: involves: 101/H * C3H/HeH

 MP:0000373 belly spot "the appearance of a round area of white fur on the belly" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Tyrc-ch49H/Tyrc-ch49H
Genetic Background: involves: C3H/HeH

 MP:0000394 absent melanin granules in hair follicle "missing pigment polymers in the hair follicles" [J:18378]
Show

Allelic Composition: Tyrc-2J/Tyrc-2J
Genetic Background: B6(Cg)-Tyrc-2J/J

Allelic Composition: Tyrcm1OR/Tyrcm1OR
Genetic Background: C3H/Rl

 MP:0000411 shiny fur "fur with a glossy or glistening appearance" [J:45065]
Show

Allelic Composition: Tyrc-p/Tyrc-p
Genetic Background: involves: AKR/J * DBA/2J

 MP:0000421 mottled coat "coat has spots, streaks, and/or blotches of a different color" [J:17194]
Show

Allelic Composition: Tyrcm1OR/Tyrcm1OR
Genetic Background: C3H/Rl

Allelic Composition: Tyrcm1OR/Tyrc
Genetic Background: involves: C3H/Rl

Allelic Composition: Tyrcm1OR/Tyrc-ch
Genetic Background: involves: C3H/Rl

Allelic Composition: Tyrc-ch49H/Tyrc-ch49H
Genetic Background: involves: C3H/HeH

Allelic Composition: Tyrc/Tyrc-ch49H
Genetic Background: involves: C3H/HeH

 MP:0001004 abnormal photoreceptor morphology "structural or developmental anomaly of the receptors sensitive to light " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Tyrc-2J/Tyrc-2J
Genetic Background: B6(Cg)-Tyrc-2J/J

 MP:0001189 absent skin pigmentation "lack of pigmentation of the skin" [J:53370]
Show

Allelic Composition: Ptstm1Thny/Ptstm1Thny
Genetic Background: involves: 129/Sv * C57BL/6

Allelic Composition: Tyrc-2J/Tyrc-2J
Genetic Background: B6(Cg)-Tyrc-2J/J

Allelic Composition: Tyrc-Brd/Tyrc-Brd
Genetic Background: C57BL/6Brd-Tyrc-Brd

Allelic Composition: Tyrc-2J/Tyrc-2J
Genetic Background: involves: C57BL/6

Allelic Composition: Tyrc-19J/Tyrc-19J
Genetic Background: 129P1/ReJ-Tyrc-19J

Allelic Composition: Tyrc-18J/Tyrc-18J
Genetic Background: C57BL/6J H2bm3/EgJ-Tyrc-18J

Allelic Composition: Mlanatm1.2Bee/Mlanatm1.2Bee,Tyrc/Tyrc
Genetic Background: involves: 129S/SvEv * C57BL/6 * FVB/N * SJL

Allelic Composition: Tyrem3J/Tyrem3J
Genetic Background: Not Specified

 MP:0001224 abnormal keratinocyte apoptosis "aberrant programmed cell death of keratin producing cells of the epidermis" [J:64948]
Show

Allelic Composition: Tyrc-2J/Tyrc-2J
Genetic Background: B6(Cg)-Tyrc-2J/J

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
Show

Allelic Composition: Tenm4l7Rn3-1R/Tenm4l7Rn3-1R
Genetic Background: FRCH.Cg-Tenm4l7Rn3-2R

Allelic Composition: Lgi1tm1.1Jkc/Lgi1tm1.1Jkc,Tyrc-Brd/Tyrc-Brd
Genetic Background: B6.Cg-Tyrc-Brd Lgi1tm1.1Jkc

 MP:0001303 abnormal lens morphology "malformed transparent structure of the eye responsible for focusing light rays" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:40203]
Show

Allelic Composition: Foxn1nu/Foxn1+
Genetic Background: C.Cg-Foxn1nu

 MP:0001304 cataracts "complete or partial opacity of the lens" [J:65031]
Show

Allelic Composition: Foxn1nu/Foxn1+
Genetic Background: C.Cg-Foxn1nu

 MP:0001324 abnormal eye pigmentation "change in the normal black pigmentation of the eye to another color, or lack of color" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Tyrc/Tyrc-a
Genetic Background: involves: C3H/HeJ

Allelic Composition: Lgi1tm1.1Jkc/Lgi1tm1.1Jkc,Tyrc-Brd/Tyrc-Brd
Genetic Background: B6.Cg-Tyrc-Brd Lgi1tm1.1Jkc

Allelic Composition: Lgi1tm1.1Jkc/Lgi1+,Tyrc-Brd/Tyrc-Brd
Genetic Background: B6.Cg-Tyrc-Brd Lgi1tm1.1Jkc

Allelic Composition: Tyrc-44H/Tyrc-44H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Tyrc/Tyrc-44H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Tyrc-em/Tyrc-em
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: a/a,Tyrem2Ove/Tyrem2Ove
Genetic Background: involves: C57BL/6 * FVB

Allelic Composition: a/a,Tyrem4Ove/Tyrem4Ove
Genetic Background: involves: C57BL/6 * FVB

Allelic Composition: a/a,Tyrc/Tyrem4Ove
Genetic Background: involves: C57BL/6 * FVB

Allelic Composition: A/?,Tyrem7Ove/Tyrem7Ove
Genetic Background: involves: C57BL/6 * FVB

 MP:0001325 abnormal retina morphology "structural or developmental anomaly of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Tyrc-2J/Tyrc-2J
Genetic Background: B6(Cg)-Tyrc-2J/J

 MP:0001326 retinal degeneration "pathological change in the thin layer of neural tissue lining the back of the eyeball, which contains visual receptors and can result in the impairment or cessation of retinal neural function" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, NMF:Stephanie Pretel, Neuroscience Mutagenesis Facility Curator]
Show

Allelic Composition: Tyrc-2J/Tyrc-2J
Genetic Background: B6(Cg)-Tyrc-2J/J

 MP:0001327 reduced retinal photoreceptor cell number "fewer than the expected number of rods and/or cones" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Tyrc-2J/Tyrc-2J
Genetic Background: B6(Cg)-Tyrc-2J/J

 MP:0001392 abnormal locomotor activity "altered ability or inability to move from place to place" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Mecp2em1Dkatz/Mecp2+,Tyrc-ch/Tyrc-ch
Genetic Background: FVB.Cg-Pde6b+ Tyrc-ch Mecp2em1Dkatz/J

 MP:0001510 abnormal coat appearance "coat that looks different from the usual state " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Tyrc-h/Tyrc-h
Genetic Background: involves: AKR/J * DBA/2J

Allelic Composition: Tyrc-h/Tyrc
Genetic Background: involves: AKR/J * DBA/2J

Allelic Composition: A/A,Tyrc-ch/Tyrc-ch
Genetic Background: Not Specified

 MP:0001622 abnormal vasculogenesis "aberrant process of the initial establishment of the vascular network " [J:67296, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Tenm4l7Rn3-4R/Tyrc-26DVT
Genetic Background: involves: 101/Rl * BALB/cRl * C3H/Rl * C57BL/10Rl * T-stock

 MP:0001683 absent mesoderm "missing or failure to differentiate the middle primary germ layer " [J:40594]
Show

Allelic Composition: Mesdtm2.1Bch/Tyrc-3YPSd
Genetic Background: involves: 101/Rl * C3H/Rl * C57BL/6 * C57BL/6J

 MP:0001696 failure to gastrulate "inability to differentiate and invaginate the primary germ layers" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:34458]
Show

Allelic Composition: Mesdtm1Bch/Mesdtm2.1Bch
Genetic Background: involves: 129 * C57BL/6 * C57BL/6J

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Tyrc/Tyrc-43H
Genetic Background: involves: 101/H * C3H/HeH

 MP:0001926 female infertility "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193]
Show

Allelic Composition: Mecp2em1Dkatz/Mecp2+,Tyrc-ch/Tyrc-ch
Genetic Background: FVB.Cg-Pde6b+ Tyrc-ch Mecp2em1Dkatz/J

 MP:0002064 seizures "sudden and often acute manifestation of epileptic attack, sometimes convulsive" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Sh3pxd2bGt(GST_1527_E5)Lex/Sh3pxd2bGt(GST_1527_E5)Lex
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0002075 abnormal coat color "irregular or unusual pigmentation pattern of the hair in relation to control animals" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: a/a,Tyrc-i/Tyrc-i
Genetic Background: involves: STOCK Tyrc-r

Allelic Composition: Oca2p/Oca2p,Tyrc-i/Tyrc-i
Genetic Background: involves: STOCK Tyrc-r

Allelic Composition: Tyrskc35/Tyrskc35
Genetic Background: Not Specified

Allelic Composition: Tyrc-h/Tyrc-25H
Genetic Background: STOCK Tyrc-h/Tyrc-25H

Allelic Composition: Tyrc-a/Tyrc-a
Genetic Background: C3H/HeJ-Tyrc-a/J

Allelic Composition: Tyrc-p/Tyrc-p
Genetic Background: involves: AKR/J * DBA/2J

Allelic Composition: Tyrc/Tyrc-a
Genetic Background: involves: C3H/HeJ

Allelic Composition: Tyrc-a/Tyrc-ch
Genetic Background: involves: C3H/HeJ

Allelic Composition: Tyrc-a/Tyrc-e
Genetic Background: involves: C3H/HeJ

Allelic Composition: Tyrc-a/Tyrc-h
Genetic Background: involves: C3H/HeJ

Allelic Composition: Tyrc-Bc/Tyrc
Genetic Background: involves: SELH/Bc * SWV/Bc

Allelic Composition: Tyrc-h/Tyrc-h
Genetic Background: involves: AKR/J * DBA/2J

Allelic Composition: Tyrc-h/Tyrc
Genetic Background: involves: AKR/J * DBA/2J

Allelic Composition: Tyrc-p/Tyrc
Genetic Background: Not Specified

Allelic Composition: Tyrcm1OR/Tyrcm1OR
Genetic Background: C3H/Rl

Allelic Composition: Tyrcm1OR/Tyrc
Genetic Background: involves: C3H/Rl

Allelic Composition: Tyrcm1OR/Tyrc-ch
Genetic Background: involves: C3H/Rl

Allelic Composition: Tyrc-ch/Del(7)Tyrc-3H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Lgi1tm1.1Jkc/Lgi1tm1.1Jkc,Tyrc-Brd/Tyrc-Brd
Genetic Background: B6.Cg-Tyrc-Brd Lgi1tm1.1Jkc

Allelic Composition: Tyrc-Bc2/Tyrc-Bc2
Genetic Background: SELH/Bc

Allelic Composition: Tyrc-Bc3/Tyrc-Bc3
Genetic Background: SELH/Bc

Allelic Composition: Tyrc-10J/Tyrc-10J
Genetic Background: CBA/J

Allelic Composition: Tyrc-11J/Tyrc-11J
Genetic Background: C57BL/10SnJ

Allelic Composition: Tyrc-9J/Tyrc-9J
Genetic Background: C3H/HeJ-Tyrc-9J/J

Allelic Composition: Tyrc-44H/Tyrc-44H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Tyrc-m/Tyrc-m
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Tyrc-ch/Del(7)Tyrc-6H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: A/A,Tyrc-ch/Tyrc-ch
Genetic Background: Not Specified

 MP:0002080 prenatal lethality "death anytime between fertilization and E18.5" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ppargtm1Tka/Pparg+
Genetic Background: involves: C57BL/6 * CBA * ICR

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Tyrc-202G/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Gt(ROSA)26Sortm2Thl/Gt(ROSA)26Sor+,Ptentm1Hwu/Ptentm1Hwu,Tyrc-Brd/Tyrc-Brd
Genetic Background: involves: 129/Sv * 129S4/SvJae * C57BL/6

Allelic Composition: Gt(ROSA)26Sortm2Thl/Gt(ROSA)26Sor+,Ptentm1Hwu/Ptentm1Hwu,Trp53tm1Thl/Trp53tm1Thl,Tyrc-Brd/Tyrc-Brd
Genetic Background: involves: 129/Sv * 129S4/SvJae * C57BL/6

Allelic Composition: Mecp2em1Dkatz/Y,Tyrc-ch/Tyrc-ch
Genetic Background: FVB.Cg-Pde6b+ Tyrc-ch Mecp2em1Dkatz/J

 MP:0002090 abnormal vision "inability or decreased ability to see " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Tyrc-2J/Tyrc-2J
Genetic Background: B6(Cg)-Tyrc-2J/J

 MP:0002095 abnormal skin pigmentation "variation of skin color or complexion" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Tyrcm1OR/Tyrcm1OR
Genetic Background: C3H/Rl

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Axin1Fu/Axin1+
Genetic Background: involves: M. m. bactrianus

Allelic Composition: Tyrc-ch83R/Tyr+
Genetic Background: involves: 101/Rl * C3H/Rl * T-stock

Allelic Composition: Tyrc-40H/Tyrc-40H
Genetic Background: involves: C3H/HeH

Allelic Composition: Ltftm1(icre)Tdku/Ltftm1(icre)Tdku,Tyrc-2J/Tyrc-2J
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0002411 decreased susceptibility to bacterial infection "reduced likelihood that an organism will develop ill effects from a bacterial infection or from components of or toxins produced by bacteria " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Gt(ROSA)26Sortm3(NOTCH3*R1031C)Sat/Gt(ROSA)26Sor+,Tg(Tagln-cre)1Her/0
Genetic Background: involves: 129S2/SvEv * 129S6/SvEvTac * C57BL/6 * SJL

 MP:0003111 abnormal nucleus morphology "abnormalities in the nucleus and/or its surrounding membrane" [J:91473, smb:Susan M. Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Rfngtm2.1Tfv/Rfngtm2.1Tfv
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac

 MP:0003136 yellow coat color "amount and distribution of yellow pigment (phaeomelanin) relative to black or brown pigment (eumelanin) is increased compared to wild-type agouti" [llw2:Linda L. Washburn, Mouse Genome Informatics Curator]
Show

Allelic Composition: Foxn1nu/Foxn1+
Genetic Background: C.Cg-Foxn1nu

 MP:0003234 enhanced NMDA-mediated synaptic currents "increase in the measured amplitude or duration of response to stimulation of NMDA receptors" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Lgi1tm1.1Jkc/Lgi1tm1.1Jkc,Tyrc-Brd/Tyrc-Brd
Genetic Background: B6.Cg-Tyrc-Brd Lgi1tm1.1Jkc

 MP:0003400 kinked neural tube "twists or kinks in the embryonic neural tube" [J:66514, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
Show

Allelic Composition: Tenm4l7Rn3-4R/Tyrc-26DVT
Genetic Background: involves: 101/Rl * BALB/cRl * C3H/Rl * C57BL/10Rl * T-stock

 MP:0003406 failure of zygotic cell division "inability of a fertilized oocyte to initiate or complete early cell divisions" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Rfngtm2.1Tfv/Rfngtm2.1Tfv
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac

 MP:0003604 single kidney 
Show

Allelic Composition: Tyrc/Tyrc-43H
Genetic Background: involves: 101/H * C3H/HeH

 MP:0003642 absent seminal gland "absence of the two folded, sac shaped, glands that is a diverticulum of the ductus deferens " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Tyrc/Tyrc-43H
Genetic Background: involves: 101/H * C3H/HeH

 MP:0003702 abnormal chromosome morphology "anomalies in the structure of the compact, intertwined molecules of DNA found in the nucleus which carry genetic information " [hdene:Howard Dene , Mouse Genome Informatics Curator]
Show

Allelic Composition: Slc6a3tm1(cre)Xz/Slc6a3+
Genetic Background: involves: 129S1/Sv * C57BL/6 * SJL

 MP:0003721 increased tumor growth/size "greater than expected development of tumorous growth when compared to controls" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Gt(ROSA)26Sortm2Thl/Gt(ROSA)26Sor+,Ptentm1Hwu/Ptentm1Hwu,Trp53tm1Thl/Trp53tm1Thl,Tyrc-Brd/Tyrc-Brd
Genetic Background: involves: 129/Sv * 129S4/SvJae * C57BL/6

 MP:0003962 abnormal adrenaline level "aberrant concentration in the blood or tissues of this catacholamine hormone that stimulates the adrenergic receptors and that causes systemic vasoconstriction and gastrointestinal relaxation, stimulates the heart, and dilates bronchi and cerebral vessels" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Thtm1Srt/Thtm1Srt,Tyrc/Tyrc
Genetic Background: involves: 129S2/SvPas * C57BL/6J * ICR

 MP:0003964 abnormal noradrenaline level "aberrant concentration of this precursor of epinephrine that is a widespread central and autonomic neurotransmitter" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Thtm1Srt/Thtm1Srt,Tyrc/Tyrc
Genetic Background: involves: 129S2/SvPas * C57BL/6J * ICR

 MP:0003984 embryonic growth retardation "slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Tenm4l7Rn3-4R/Tyrc-26DVT
Genetic Background: involves: 101/Rl * BALB/cRl * C3H/Rl * C57BL/10Rl * T-stock

 MP:0003996 clonic seizures "increased number or decreased threshold for the induction of a seizure characterized by unilateral or bilateral rhythmic jerking movements of the arms and legs caused by alternating contraction and relaxation of muscle" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Lgi1tm1.1Jkc/Lgi1tm1.1Jkc,Tyrc-Brd/Tyrc-Brd
Genetic Background: B6.Cg-Tyrc-Brd Lgi1tm1.1Jkc

 MP:0004028 chromosome breakage "chromosome instability in the from of increased frequency of spontaneous breakage with or without rearrangements" [llw2:Linda Washburn , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ldlrtm1Her/Ldlrtm1Her
Genetic Background: involves: 129S7/SvEvBrd

 MP:0004030 induced chromosome breakage "chromosome breakage following treatment with a DNA-damaging agent " [llw2:Linda Washburn , Mouse Genome Informatics Curator]
Show

Allelic Composition: Slc6a3tm1(cre)Xz/Slc6a3+
Genetic Background: involves: 129S1/Sv * C57BL/6 * SJL

Allelic Composition: Tyrc-25H/Tyr+
Genetic Background: involves: SM/J * STOCK Tyrc-h/Tyrc-25H

 MP:0004221 abnormal iridocorneal angle "any structural abnormality of the acute angle occurring between the iris and the cornea at the periphery of the anterior chamber of the eye" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cyp1b1tm1Gonz/Cyp1b1tm1Gonz,Tyrc-2J/Tyrc-2J
Genetic Background: B6.Cg-Tyrc-2J Cyp1b1tm1Gonz

 MP:0004222 synechia "an adhesion of parts, especially involving the iris e.g. attachments of the iris to the trabecular meshwork and peripheral cornea" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Foxc1tm1Blh/Foxc1+,Tyrc-2J/Tyrc-2J
Genetic Background: B6.Cg-Tyrc-2J Foxc1tm1Blh

 MP:0004226 absent Schlemm s canal "absence of the vascular structure encircling the anterior chamber of the eye, through which the aqueous humor is returned to the blood circulation" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cyp1b1tm1Gonz/Cyp1b1tm1Gonz,Tyrc-2J/Tyrc-2J
Genetic Background: B6.Cg-Tyrc-2J Cyp1b1tm1Gonz

Allelic Composition: Foxc1tm1Blh/Foxc1+,Tyrc-2J/Tyrc-2J
Genetic Background: B6.Cg-Tyrc-2J Foxc1tm1Blh

 MP:0004227 increased cellular sensitivity to ionizing radiation "increased incidence of cell death following exposure to high levels of ionizing radiation" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tyrc-2J/Tyrc-2J
Genetic Background: B6(Cg)-Tyrc-2J/J

 MP:0004244 abnormal spontaneous abortion rate "change in frequency of a natural or accidental termination of a pregnancy at a stage where the embryo or the fetus is incapable of surviving independently of the mother" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tyrc/Tyrc-43H
Genetic Background: involves: 101/H * C3H/HeH

 MP:0004381 abnormal hair follicle melanocyte morphology "any structural anomaly of the cells that produce pigment in the hair follicles" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Mlanatm1.2Bee/Mlanatm1.2Bee,Tyrc/Tyrc
Genetic Background: involves: 129S/SvEv * C57BL/6 * FVB/N * SJL

 MP:0004382 abnormal hair follicle melanogenesis "failure of or anomaly in the biosynthetic pathway of melanin formation in hair follicles" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tyrc-p/Tyrc-p
Genetic Background: involves: C57BL/6

 MP:0004608 abnormal cervical axis morphology "any structural anomaly of the second cervical vertebra (C2) which forms the pivot upon which the first cervical (atlas, C1) vertebra rotates" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tenm4l7Rn3-4R/Tyrc-26DVT
Genetic Background: involves: 101/Rl * BALB/cRl * C3H/Rl * C57BL/10Rl * T-stock

 MP:0004621 lumbar vertebral fusion "the union of one or more lumbar vertebrae into a single structure" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tenm4l7Rn3-4R/Tyrc-26DVT
Genetic Background: involves: 101/Rl * BALB/cRl * C3H/Rl * C57BL/10Rl * T-stock

 MP:0004623 thoracic vertebral fusion "the union of one or more thoracic vertebrae into a single structure" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tenm4l7Rn3-4R/Tyrc-26DVT
Genetic Background: involves: 101/Rl * BALB/cRl * C3H/Rl * C57BL/10Rl * T-stock

 MP:0004753 abnormal miniature excitatory postsynaptic currents "defect in the size or duration of spontaneous currents detected in postsynaptic cells that occur in the absence of an excitatory impulse" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Lgi1tm1.1Jkc/Lgi1tm1.1Jkc,Tyrc-Brd/Tyrc-Brd
Genetic Background: B6.Cg-Tyrc-Brd Lgi1tm1.1Jkc

 MP:0005075 abnormal melanosome morphology "anomalous structure of these tissue-specific cytoplasmic organelles within which melanin pigments are synthesized and stored" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:5346]
Show

Allelic Composition: Tyrc-2J/Tyrc-2J
Genetic Background: B6(Cg)-Tyrc-2J/J

Allelic Composition: a/a,Lystbg/Lystbg,Tyrc/Tyrc
Genetic Background: involves: C3H/Rl * C57BL/6J

 MP:0005077 abnormal melanogenesis "failure of or anomaly in the biosynthetic pathway of melanin formation in cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:5346]
Show

Allelic Composition: Lfngtm1Rjo/Lfngtm1Rjo,Mesp2tm15.1(Lfng)Ysa/Mesp2+
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: a/a,Lystbg/Lystbg,Tyrc/Tyrc
Genetic Background: involves: C3H/Rl * C57BL/6J

 MP:0005102 abnormal iris pigmentation "anomalous coloring of the adjustable membrane, composed of the stroma and pigmented epithelium, located just in front of the crystalline lens within the eye" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Tyrc-h/Tyrc-h
Genetic Background: B6.Cg-Tyrc-h/J

 MP:0005171 lack of coat pigmentation "fur is devoid of coloration and appears white " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:83500]
Show

Allelic Composition: Ptstm1Thny/Ptstm1Thny
Genetic Background: involves: 129/Sv * C57BL/6

Allelic Composition: Tyrc-2J/Tyrc-2J
Genetic Background: B6(Cg)-Tyrc-2J/J

Allelic Composition: Tyrc-Brd/Tyrc-Brd
Genetic Background: C57BL/6Brd-Tyrc-Brd

Allelic Composition: Tyrc-Btlr/Tyrc-Btlr
Genetic Background: C57BL/6J-Tyrc-Btlr

Allelic Composition: Tyrc-10FR60L/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-10R75M/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-112K/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-11DSD/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-12FR60Hb/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-12HATh/Tyrc-12HATh
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-12HATh/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-146G/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-14CoS/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-14FR60Hb/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-15DSD/Tyrc-15DSD
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-15DSD/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-15R145M/Tyrc-15R145M
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-15R145M/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-15R60L/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-16DFiOD/Tyrc-16DFiOD
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-16DFiOD/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-16HATh/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-177G/Tyrc-177G
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-177G/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-17UThc/Tyrc-17UThc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-17UThc/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-19DTR/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-1DThWb/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-1FAFyh/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-1FATw/Tyrc-1FATw
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-1FATw/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-1FDFoHrc/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-1FR60Hb/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-202G/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-20FATw/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-222THO-I/Tyrc-222THO-I
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-222THO-I/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-23DVT/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-24R145L/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-24R75M/Tyrc-24R75M
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-24R75M/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-27FrThc/Tyrc-27FrThc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-27FrThc/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-2CHLb/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-2MLPm/Tyrc-2MLPm
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-2MLPm/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-2R145L/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-2YPSj/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-3YPSd/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-68G/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-7R250H/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-4PB/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-39SAS/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-3R60L/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-3R145L/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-9FR60Hb/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-AL/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-4FR60Hd/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-5FR60Hg/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-LA/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-65K/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-31HATh/Tyrc-31HATh
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-31HATh/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-32DSD/Tyrc-32DSD
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-32DSD/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-38R145L/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-38R145L/Tyrc-38R145L
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-3FAFyh/Tyrc-3FAFyh
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-3FAFyh/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-3FDFoHrd/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-3FDFoHrd/Tyrc-3FDFoHrd
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-3FR60Hb/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-3FR60Hb/Tyrc-3FR60Hb
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-45DSD/Tyrc-45DSD
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-45DSD/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-4CFO/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-4CFO/Tyrc-4CFO
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-51DTD/Tyrc-51DTD
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-51DTD/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-62DSD/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-62DSD/Tyrc-62DSD
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-65G/Tyrc-65G
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-65G/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-6THO-IV/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-6THO-IV/Tyrc-6THO-IV
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-76UT/Tyrc-76UT
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-76UT/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-77HATh/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-77HATh/Tyrc-77HATh
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-7THO-II/Tyrc-7THO-II
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-7THO-II/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-9Pub/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-9Pub/Tyrc-9Pub
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-3DENb/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-19J/Tyrc-19J
Genetic Background: 129P1/ReJ-Tyrc-19J

Allelic Composition: Tyrc-18J/Tyrc-18J
Genetic Background: C57BL/6J H2bm3/EgJ-Tyrc-18J

Allelic Composition: Tyrc-4J/Tyrc-4J
Genetic Background: B10.D2/nSn-Tyrc-4J/J

Allelic Composition: Tyrc-45H/Tyrc-45H
Genetic Background: Not Specified

Allelic Composition: Tyrc-46H/Tyrc-46H
Genetic Background: Not Specified

Allelic Composition: Tyrc-Bc/Tyrc
Genetic Background: involves: SELH/Bc * SWV/Bc

Allelic Composition: Tyrc/Del(7)Tyrc-3H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Lgi1tm1.1Jkc/Lgi1+,Tyrc-Brd/Tyrc-Brd
Genetic Background: B6.Cg-Tyrc-Brd Lgi1tm1.1Jkc

Allelic Composition: Tyrc-2Btlr/Tyrc-2Btlr
Genetic Background: C57BL/6J-Tyrc-2Btlr

Allelic Composition: Tyrc-Bc2/Tyrc-Bc2
Genetic Background: SELH/Bc

Allelic Composition: Tyrc-Bc3/Tyrc-Bc3
Genetic Background: SELH/Bc

Allelic Composition: Tyrc-10J/Tyrc-10J
Genetic Background: CBA/J

Allelic Composition: Tyrc-11J/Tyrc-11J
Genetic Background: C57BL/10SnJ

Allelic Composition: Tyrc-9J/Tyrc-9J
Genetic Background: C3H/HeJ-Tyrc-9J/J

Allelic Composition: Tyrc-44H/Tyrc-44H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Tyrc/Tyrc-44H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Tyrc/Tyrc-26DVT
Genetic Background: involves: 101/Rl * C3H/Rl * T-stock

Allelic Composition: Tyrc-43H/Tyrc-ch
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Tyrc/Tyrc-43H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Tyrc-50H/Tyrc-50H
Genetic Background: involves: 101/H

Allelic Composition: Tyrc-51H/Tyrc-51H
Genetic Background: involves: 101/H

Allelic Composition: Tyrc-17J/Tyrc-17J
Genetic Background: involves: C57BLKS/J

Allelic Composition: Tyrc/Tyrc-13J
Genetic Background: (C57BL/6J x SJL/J)F1

Allelic Composition: Tyrc-Wtsi/Tyrc-Wtsi
Genetic Background: C57BL/6N-Tyrc-Wtsi/Wtsi

Allelic Composition: Tyrem3J/Tyrem3J
Genetic Background: Not Specified

Allelic Composition: Tyrem2Utr/Tyrem1Utr
Genetic Background: involves: C57BL/6J

Allelic Composition: Tyrem2Utr/Tyrem2Utr
Genetic Background: involves: C57BL/6J

Allelic Composition: Tyrtm1Arte/Tyrtm1Arte
Genetic Background: C57BL/6NTac-Tyrtm1Arte

Allelic Composition: Atm1.1Arte/Atm1.1Arte,Tyrtm1Arte/Tyrtm1Arte
Genetic Background: C57BL/6NTac-Atm1.1Arte Tyrtm1Arte

Allelic Composition: Tyrc/Tyrem3Ove
Genetic Background: involves: C57BL/6 * FVB

Allelic Composition: Tyrem11Ove/Tyrem11Ove
Genetic Background: involves: C57BL/6 * FVB

 MP:0005172 lack of eye pigmentation "visual organs are devoid of coloring pigment in relation to control animals, usually resulting in a red or pink color" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:83500]
Show

Allelic Composition: Ptstm1Thny/Ptstm1Thny
Genetic Background: involves: 129/Sv * C57BL/6

Allelic Composition: Tyrc-Brd/Tyrc-Brd
Genetic Background: C57BL/6Brd-Tyrc-Brd

Allelic Composition: Tyrc-h/Tyrc-h
Genetic Background: involves: AKR/J * DBA/2J

Allelic Composition: Tyrc-h/Tyrc
Genetic Background: involves: AKR/J * DBA/2J

Allelic Composition: Tyrc-44H/Tyrc-44H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Tyrm3Btlr/Tyrm3Btlr
Genetic Background: involves: C57BL/6J

Allelic Composition: Tyrc/Tyrc-ch62H
Genetic Background: involves: BALB/c * C3H/HeH

Allelic Composition: A/?,Tyrc/Tyrem1Ove
Genetic Background: involves: C57BL/6 * FVB

Allelic Composition: Tyrc/Tyrem8Ove
Genetic Background: involves: C57BL/6 * FVB

Allelic Composition: A/?,Tyrem9Ove/Tyrem9Ove
Genetic Background: involves: C57BL/6 * FVB

Allelic Composition: A/?,Tyrem12Ove/Tyrem12Ove
Genetic Background: involves: C57BL/6 * FVB

Allelic Composition: a/a,Tyrc/Tyrem2Ove
Genetic Background: involves: C57BL/6 * FVB

 MP:0005174 abnormal tail pigmentation "anomalous color of the tail in relation to control animals" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: a/a,Tyrem2Ove/Tyrem2Ove
Genetic Background: involves: C57BL/6 * FVB

 MP:0005198 abnormal aqueous drainage system morphology "anomalies in the structures associated with drainage of the aqueous humor from the eye, these include the trabecular meshwork, Schlemm s canal, the uveoscleral network, and the aqueous veins " [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Tyrc-2J/Tyrc-2J
Genetic Background: B6(Cg)-Tyrc-2J/J

Allelic Composition: Foxc1tm1Blh/Foxc1+,Tyrc-2J/Tyrc-2J
Genetic Background: B6.Cg-Tyrc-2J Foxc1tm1Blh

 MP:0005203 abnormal trabecular meshwork morphology "structural anomaly in the porelike structure surrounding the entire circumference of the anterior chamber through which aqueous humor circulates" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Cyp1b1tm1Gonz/Cyp1b1tm1Gonz,Tyrc-2J/Tyrc-2J
Genetic Background: B6.Cg-Tyrc-2J Cyp1b1tm1Gonz

Allelic Composition: Foxc1tm1Blh/Foxc1+,Tyrc-2J/Tyrc-2J
Genetic Background: B6.Cg-Tyrc-2J Foxc1tm1Blh

 MP:0005241 abnormal retinal ganglion layer morphology "anomalous structure of the innermost nuclear layer of the retina, which projects axons through the optic nerve to the brain " [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Tyrc-2J/Tyrc-2J
Genetic Background: B6(Cg)-Tyrc-2J/J

 MP:0005253 abnormal eye physiology "anomalous function and/or activity of the ocular system or any of its parts" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Tyrc-2J/Tyrc-2J
Genetic Background: B6(Cg)-Tyrc-2J/J

 MP:0005257 abnormal intraocular pressure "anomaly in the amount of force per unit area exerted by the intraocular fluid within the eye" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Tyrc-2J/Tyrc-2J
Genetic Background: B6(Cg)-Tyrc-2J/J

 MP:0005366 variegated coat color "dappled coloration of the fur; mosaic" [llw2:Linda Washburn , Mouse Genome Informatics Curator]
Show

Allelic Composition: Tyrc-em/Tyrc-em
Genetic Background: involves: 101/H * C3H/HeH

 MP:0005408 hypopigmentation "dilution of the pigment in the body" [llw2:Linda Washburn , Mouse Genome Informatics Curator]
Show

Allelic Composition: Tyrc-p/Tyrc-p
Genetic Background: involves: AKR/J * DBA/2J

Allelic Composition: Tyrc/Tyrc-ch62H
Genetic Background: involves: BALB/c * C3H/HeH

 MP:0005643 decreased dopamine level "less than the normal concentration of this catecholamine neurotransmitter, dervied from tyrosine and the precursor to norepinephrine and epinephrine" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, J:88298]
Show

Allelic Composition: Thtm1Srt/Thtm1Srt,Tyrc/Tyrc
Genetic Background: involves: 129S2/SvPas * C57BL/6J * ICR

 MP:0005650 abnormal limb bud morphology "aberrant structure or development of any of the swellings on the trunk of the embryo that become limbs" [hdene:Howard Dene , Mouse Genome Informatics Curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003, J:61460]
Show

Allelic Composition: Tenm4l7Rn3-4R/Tyrc-26DVT
Genetic Background: involves: 101/Rl * BALB/cRl * C3H/Rl * C57BL/10Rl * T-stock

 MP:0006159 ocular albinism "absence of melanin production in the eye only" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Tyrc-2J/Tyrc-2J
Genetic Background: B6(Cg)-Tyrc-2J/J

Allelic Composition: Tyrcm1OR/Tyrcm1OR
Genetic Background: C3H/Rl

Allelic Composition: Tyrc-10J/Tyrc-10J
Genetic Background: CBA/J

Allelic Composition: Tyrc-11J/Tyrc-11J
Genetic Background: C57BL/10SnJ

Allelic Composition: Tyrc-9J/Tyrc-9J
Genetic Background: C3H/HeJ-Tyrc-9J/J

Allelic Composition: Tyrc-h/Tyrc-h
Genetic Background: B6.Cg-Tyrc-h/J

Allelic Composition: Tyrc-Wtsi/Tyrc-Wtsi
Genetic Background: C57BL/6N-Tyrc-Wtsi/Wtsi

 MP:0006370 abnormal phaeomelanin content "anomaly in the amount or distribution of yellow pigment in the hair" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: A/A,Tyrc-ch/Tyrc-ch
Genetic Background: Not Specified

 MP:0008480 absent eye pigmentation "absence of melanin (pigment) in the eye either due to absent melanocytes or failure of melanin synthesis" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tyrc-Btlr/Tyrc-Btlr
Genetic Background: C57BL/6J-Tyrc-Btlr

Allelic Composition: Tyrc-112K/Tyrc-112K
Genetic Background: involves: 101/R1 * C3Hf/R1 * St.2A

Allelic Composition: Tyrc-p/Tyrc-p
Genetic Background: involves: AKR/J * DBA/2J

Allelic Composition: Tyrc-Bc/Tyrc
Genetic Background: involves: SELH/Bc * SWV/Bc

Allelic Composition: Tyrc-h/Tyrc-h
Genetic Background: involves: AKR/J * DBA/2J

Allelic Composition: Tyrcm1OR/Tyrcm1OR
Genetic Background: C3H/Rl

Allelic Composition: Tyrc-2Btlr/Tyrc-2Btlr
Genetic Background: C57BL/6J-Tyrc-2Btlr

Allelic Composition: Tyrc-Bc2/Tyrc-Bc2
Genetic Background: SELH/Bc

Allelic Composition: Tyrc-Bc3/Tyrc-Bc3
Genetic Background: SELH/Bc

Allelic Composition: Tyrc-43H/Tyrc-ch
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Tyrc/Tyrc-43H
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Tyrc-17J/Tyrc-17J
Genetic Background: involves: C57BLKS/J

Allelic Composition: Tyrc/Tyrc-13J
Genetic Background: (C57BL/6J x SJL/J)F1

Allelic Composition: Tyrem3J/Tyrem3J
Genetic Background: Not Specified

Allelic Composition: Tyrem2Utr/Tyrem1Utr
Genetic Background: involves: C57BL/6J

Allelic Composition: Tyrtm1Arte/Tyrtm1Arte
Genetic Background: C57BL/6NTac-Tyrtm1Arte

Allelic Composition: Atm1.1Arte/Atm1.1Arte,Tyrtm1Arte/Tyrtm1Arte
Genetic Background: C57BL/6NTac-Atm1.1Arte Tyrtm1Arte

Allelic Composition: Tyrem11Ove/Tyrem11Ove
Genetic Background: involves: C57BL/6 * FVB

 MP:0008574 decreased circulating interferon-alpha level "reduction in the amount in the blood of one of the type I interferons produced by peripheral blood leukocytes or lymphoblastoid cells that has antiviral activity and activates natural killer cells and B cells" [MESH:D12.644.276.374.440.890.250]
Show

Allelic Composition: Ifnb1tm2.1Lien/Ifnb1tm2.1Lien,Tyrc-2J/Tyrc-2J,Lyz2tm1(cre)Ifo/Lyz2+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0008576 decreased circulating interferon-beta level "reduction in the amount in the blood of one of the type I interferons produced by fibroblasts in response to stimulation by live or inactivated virus or by double-stranded RNA with antiviral, antiproliferative, and immunomodulating activity" [MESH:D12.644.276.374.440.890.275]
Show

Allelic Composition: Ifnb1tm2.1Lien/Ifnb1tm2.1Lien,Tyrc-2J/Tyrc-2J,Lyz2tm1(cre)Ifo/Lyz2+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0008770 decreased survivor rate "a smaller percentage of organisms than expected survive to adulthood and have a lifespan similar to controls" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tyrc-2MLPm/Tyrc-2MLPm
Genetic Background: involves: 101/Rl * C3H/Rl

 MP:0008872 abnormal response to xenobiotics "any anomaly in the physiological or morphological changes induced by a foreign compound, such as changes in blood pressure, changes in hormone or protein levels or hypertrophy or hypotrophy of an organ" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Grid2ho/Grid2ho
Genetic Background: involves: C57BLKS/J

 MP:0008874 decreased sensitivity to xenobiotics "increase in the dose or concentration of a foreign compound required to induce a specific level of response" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Grid2ho/Grid2ho
Genetic Background: involves: C57BLKS/J

 MP:0010192 abnormal retinal melanin granule morphology "any structural anomaly of the pigment particles in the retina" [ISBN-13:978-1-4051-2034-0 "The Pigmentary System, Second Edition"]
Show

Allelic Composition: a/a,Lystbg/Lystbg,Tyrc/Tyrc
Genetic Background: involves: C3H/Rl * C57BL/6J

 MP:0010193 abnormal choroid melanin granule morphology "any structural anomaly of the pigment particles in the choroid" [ISBN-13:978-1-4051-2034-0 "The Pigmentary System, Second Edition"]
Show

Allelic Composition: a/a,Lystbg/Lystbg,Tyrc/Tyrc
Genetic Background: involves: C3H/Rl * C57BL/6J

 MP:0010231 transverse fur striping "presence of stripes of pigmented hair, usually black, of variable degree and location in the coat" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tyrc-m/Tyrc-m
Genetic Background: involves: 101/H * C3H/HeH

 MP:0010727 increased glioblastoma incidence "greater than the expected number of a fast-growing type of central nervous system tumor that forms from glial tissue of the brain and spinal cord and has cells that look very different from normal cells; glioblastoma usually occurs in adults and affects the brain more often than the spinal cord" [NCI:CDRID45698 "http://www.cancer.gov/dictionary/?CdrID=45698"]
Show

Allelic Composition: Gt(ROSA)26Sortm2Thl/Gt(ROSA)26Sor+,Ptentm1Hwu/Ptentm1Hwu,Tyrc-Brd/Tyrc-Brd
Genetic Background: involves: 129/Sv * 129S4/SvJae * C57BL/6

Allelic Composition: Gt(ROSA)26Sortm2Thl/Gt(ROSA)26Sor+,Ptentm1Hwu/Ptentm1Hwu,Trp53tm1Thl/Trp53tm1Thl,Tyrc-Brd/Tyrc-Brd
Genetic Background: involves: 129/Sv * 129S4/SvJae * C57BL/6

 MP:0010769 abnormal survival "deviation from the expected viability or life span of an organism" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tyrc-42H/Tyrc-ch
Genetic Background: involves: 101/H * C3H/HeH

 MP:0011002 enhanced AMPA-mediated synaptic currents "increase in the measured amplitude, current density or duration of response to stimulation of AMPA receptors" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Lgi1tm1.1Jkc/Lgi1tm1.1Jkc,Tyrc-Brd/Tyrc-Brd
Genetic Background: B6.Cg-Tyrc-Brd Lgi1tm1.1Jkc

 MP:0011085 complete postnatal lethality "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Lgi1tm1.1Jkc/Lgi1tm1.1Jkc,Tyrc-Brd/Tyrc-Brd
Genetic Background: B6.Cg-Tyrc-Brd Lgi1tm1.1Jkc

 MP:0011087 complete neonatal lethality "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]
Show

Allelic Composition: Atg5tm1Myok/Atg5tm1Myok,Tg(Vil1-cre)997Gum/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL

Allelic Composition: Tyrc-112K/Tyrc-112K
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-14CoS/Tyrc-14CoS
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-15R60L/Tyrc-15R60L
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-16HATh/Tyrc-16HATh
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-1FAFyh/Tyrc-1FAFyh
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-LA/Tyrc-LA
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-65K/Tyrc-65K
Genetic Background: involves: 101/Rl * C3H/Rl

 MP:0011089 complete perinatal lethality "death of all organisms of a given genotype in a population within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]
Show

Allelic Composition: Tyrc-112K/Tyrc-112K
Genetic Background: involves: 101/R1 * C3Hf/R1 * St.2A

Allelic Composition: Tyrc-10R75M/Tyrc-10R75M
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-112K/Tyrc-112K
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-55H/Tyrc-55H
Genetic Background: involves: 101/H * C3H/HeH

 MP:0011091 complete prenatal lethality "death of all organisms of a given genotype in a population between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
Show

Allelic Composition: Thtm1Srt/Thtm1Srt,Tyrc/Tyrc
Genetic Background: involves: 129S2/SvPas * C57BL/6J * ICR

Allelic Composition: Tenm4l7Rn3-4R/Tyrc-26DVT
Genetic Background: involves: 101/Rl * BALB/cRl * C3H/Rl * C57BL/10Rl * T-stock

Allelic Composition: Tyrc-2CHLb/Tyrc-2CHLb
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-2CHLb/Tyrc-202G
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-3DENb/Tyrc-3DENb
Genetic Background: involves: 101/Rl * C3H/Rl

 MP:0011092 complete embryonic lethality "death of all organisms of a given genotype in a population within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith]
Show

Allelic Composition: Ptgs2tm1Unc/Ptgs2+
Genetic Background: B6.129P2-Ptgs2tm1Unc

 MP:0011093 complete embryonic lethality at implantation "death of all organisms of a given genotype in a population at the point of implantation (Mus: E4.5)" [MGI:csmith]
Show

Allelic Composition: Tyrc-112K/Tyrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-19DTR/Tyrc-19DTR
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-1DThWb/Tyrc-1DThWb
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-202G/Tyrc-202G
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-23DVT/Tyrc-23DVT
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-24R145L/Tyrc-24R145L
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-2YPSj/Tyrc-2YPSj
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-3YPSd/Tyrc-3YPSd
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-68G/Tyrc-68G
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-7R250H/Tyrc-7R250H
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-AL/Tyrc-AL
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-4FR60Hd/Tyrc-4FR60Hd
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-5FR60Hg/Tyrc-5FR60Hg
Genetic Background: involves: 101/Rl * C3H/Rl

 MP:0011094 complete embryonic lethality before implantation "death of all organisms of a given genotype in a population between fertilization and implantation (Mus: E0 to less than E4.5)" [MGI:csmith]
Show

Allelic Composition: Rfngtm2.1Tfv/Rfngtm2.1Tfv
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac

Allelic Composition: Tyrc-10FR60L/Tyrc-10FR60L
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-12FR60Hb/Tyrc-12FR60Hb
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-146G/Tyrc-146G
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-14FR60Hb/Tyrc-14FR60Hb
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-1FDFoHrc/Tyrc-1FDFoHrc
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-1FR60Hb/Tyrc-1FR60Hb
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-26DVT/Tyrc-26DVT
Genetic Background: involves: 101/Rl * C3H/Rl * T-stock

Allelic Composition: Tyrc-2R145L/Tyrc-2R145L
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-4PB/Tyrc-4PB
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-39SAS/Tyrc-39SAS
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-3R60L/Tyrc-3R60L
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-3R145L/Tyrc-3R145L
Genetic Background: involves: 101/Rl * C3H/Rl

Allelic Composition: Tyrc-9FR60Hb/Tyrc-9FR60Hb
Genetic Background: involves: 101/Rl * C3H/Rl

 MP:0011189 small embryonic epiblast "reduced size of the tissue derived from the inner cell mass that gives rise to the ectoderm, endoderm and mesoderm of the embryo proper and to the extraembryonic mesoderm" [PMID:21123814]
Show

Allelic Composition: Mesdtm2.1Bch/Tyrc-3YPSd
Genetic Background: involves: 101/Rl * C3H/Rl * C57BL/6 * C57BL/6J

 MP:0011233 abnormal vitamin A metabolism "altered ability to metabolize any of the vitamin A compounds, retinol, retinal (retinaldehyde) and retinoic acid; animals can not synthesize vitamin A de novo, but form it through oxidative cleavage of carotenoids supplied in the diet" [GO:0035238]
Show

Allelic Composition: Plin2tm1Itl/Plin2tm1Itl,Rpe65tm1Tmr/Rpe65tm1Tmr,Tyrc-2J/Tyrc-2J
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * BALB/c * C57BL/6

 MP:0011277 decreased tail pigmentation "visually detectable dilution of pigment present on the tail surface" [MGI:csmith]
Show

Allelic Composition: a/a,Tyrem4Ove/Tyrem4Ove
Genetic Background: involves: C57BL/6 * FVB

Allelic Composition: A/?,Tyrem8Ove/Tyrem8Ove
Genetic Background: involves: C57BL/6 * FVB

Allelic Composition: A/a,Tyrem15Ove/Tyrem15Ove
Genetic Background: involves: C57BL/6 * FVB

 MP:0011279 decreased ear pigmentation "visually detectable dilution of pigment present in the outer ear" [MGI:csmith]
Show

Allelic Composition: Tyrem5Ove/Tyrem5Ove
Genetic Background: involves: C57BL/6 * FVB

Allelic Composition: Tyrc/Tyrem5Ove
Genetic Background: involves: C57BL/6 * FVB

Allelic Composition: A/?,Tyrem8Ove/Tyrem8Ove
Genetic Background: involves: C57BL/6 * FVB

 MP:0011481 anterior iris synechia "adhesion of the iris to the cornea" [MGI:anna]
Show

Allelic Composition: Cyp1b1tm1Gonz/Cyp1b1tm1Gonz,Tyrc-2J/Tyrc-2J
Genetic Background: B6.Cg-Tyrc-2J Cyp1b1tm1Gonz

 MP:0011551 variegated eye pigmentation pattern "an irregular and random patchwork of two or more colors in the eye" [MGI:llw2]
Show

Allelic Composition: Tyrem3Ove/Tyrem3Ove
Genetic Background: involves: C57BL/6 * FVB

Allelic Composition: Tyrc/Tyrem3Ove
Genetic Background: involves: C57BL/6 * FVB

Allelic Composition: Tyrem5Ove/Tyrem5Ove
Genetic Background: involves: C57BL/6 * FVB

Allelic Composition: Tyrc/Tyrem5Ove
Genetic Background: involves: C57BL/6 * FVB

Allelic Composition: Tyrem6Ove/Tyrem6Ove
Genetic Background: involves: C57BL/6 * FVB

Allelic Composition: A/?,Tyrc/Tyrem6Ove
Genetic Background: involves: C57BL/6 * FVB

Allelic Composition: A/?,Tyrem8Ove/Tyrem8Ove
Genetic Background: involves: C57BL/6 * FVB

 MP:0012143 decreased a wave amplitude "reduction in the size (height or maximum displacement) of the a wave as measured in the electroretinogram" [MGI:csmith]
Show

Allelic Composition: Tyrc-2J/Tyrc-2J
Genetic Background: B6(Cg)-Tyrc-2J/J

 MP:0012144 decreased b wave amplitude "reduction in the size (height or maximum displacement) of the b wave as measured in the electroretinogram" [MGI:csmith]
Show

Allelic Composition: Tyrc-2J/Tyrc-2J
Genetic Background: B6(Cg)-Tyrc-2J/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   


© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr