ENSMUSG00000005506


Mus musculus

Features
Gene ID: ENSMUSG00000005506
  
Biological name :Celf1
  
Synonyms : Celf1 / CUGBP Elav-like family member 1 / P28659
  
Possible biological names infered from orthology : Q92879
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: E1
Gene start: 90940382
Gene end: 91019497
  
Corresponding Affymetrix probe sets: 10473760 (MoGene1.0st)   10473779 (MoGene1.0st)   1423932_at (Mouse Genome 430 2.0 Array)   1425932_a_at (Mouse Genome 430 2.0 Array)   1426407_at (Mouse Genome 430 2.0 Array)   1426408_at (Mouse Genome 430 2.0 Array)   1427413_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000136109
Ensembl peptide - ENSMUSP00000107079
Ensembl peptide - ENSMUSP00000107082
Ensembl peptide - ENSMUSP00000005643
Ensembl peptide - ENSMUSP00000064323
Ensembl peptide - ENSMUSP00000070438
Ensembl peptide - ENSMUSP00000107075
Ensembl peptide - ENSMUSP00000107076
Ensembl peptide - ENSMUSP00000107078
NCBI entrez gene - 13046     See in Manteia.
MGI - MGI:1342295
RefSeq - XM_017315297
RefSeq - NM_001244891
RefSeq - NM_001244903
RefSeq - NM_017368
RefSeq - NM_198683
RefSeq - XM_006498664
RefSeq - XM_006498665
RefSeq - XM_006498667
RefSeq - XM_006498668
RefSeq - XM_006498669
RefSeq - XM_017315295
RefSeq - XM_006498661
RefSeq - XM_006498662
RefSeq - XM_006498663
RefSeq Peptide - NP_001231820
RefSeq Peptide - NP_001231832
RefSeq Peptide - NP_059064
RefSeq Peptide - NP_941955
swissprot - P28659
swissprot - A0A0R4J0T5
Ensembl - ENSMUSG00000005506
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 celf1ENSDARG00000005315Danio rerio
 CELF1ENSGALG00000008097Gallus gallus
 CELF1ENSG00000149187Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Celf2 / Q9Z0H4 / CUGBP Elav-like family member 2 / O95319*ENSMUSG0000000210776
Celf4 / Q7TSY6 / CUGBP Elav-like family member 4 / Q9BZC1*ENSMUSG0000002426845
Celf3 / Q8CIN6 / Mus musculus CUGBP, Elav-like family member 3 (Celf3), transcript variant 8, mRNA. / Q5SZQ8* / CUGBP Elav-like family member 3*ENSMUSG0000002813742
Celf6 / Q7TN33 / CUGBP Elav-like family member 6 / Q96J87* / AC009690.3*ENSMUSG0000003229742
Celf5 / CUGBP, Elav-like family member 5 / Q8N6W0*ENSMUSG0000003481831


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR034196  CELF1/2, RNA recognition motif 1
 IPR034198  CELF1/2, RNA recognition motif 2
 IPR034199  CELF1/2, RNA recognition motif 3
 IPR035979  RNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006376 mRNA splice site selection IDA
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0007286 spermatid development IMP
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0040018 positive regulation of multicellular organism growth IMP
 biological_processGO:0043484 regulation of RNA splicing ISS
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding ISS
 molecular_functionGO:0031369 translation initiation factor binding IDA
 molecular_functionGO:0042835 BRE binding ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001155 arrest of spermatogenesis "block of the process by which spermatogonial stem cells divide and differentiate into spermatozoa" [J:62271]
Show

Allelic Composition: Rdh12tm1.1Cahb/Rdh12tm1.1Cahb
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
Show

Allelic Composition: Rdh12tm1.1Cahb/Rdh12tm1.1Cahb
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0001922 reduced male fertility "reduced ability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61340]
Show

Allelic Composition: Rdh12tm1.1Cahb/Rdh12tm1.1Cahb
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0001923 reduced female fertility "reduced ability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Rdh12tm1.1Cahb/Rdh12tm1.1Cahb
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Rdh12tm1.1Cahb/Rdh12tm1.1Cahb
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0001935 reduced litter size "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Rdh12tm1.1Cahb/Rdh12tm1.1Cahb
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0004201 fetal growth retardation "slow or limited development during the fetal period (sensu Mus: from E14 through birth)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Rdh12tm1.1Cahb/Rdh12tm1.1Cahb
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0004884 abnormal testicular physiology "anomaly or loss either the production of male germ cells or the endocrine cells for the production testosterone" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Rdh12tm1.1Cahb/Rdh12tm1.1Cahb
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0004921 decreased placenta weight "reduction in the weight of the organ of metabolic interchange between fetus and mother" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Rdh12tm1.1Cahb/Rdh12tm1.1Cahb
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0008489 postnatal slow weight gain "the weight gain over a span of postnatal developmental time is slower than controls, with or without ever attaining a similar weight to controls as adults" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Rdh12tm1.1Cahb/Rdh12tm1.1Cahb
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Rdh12tm1.1Cahb/Rdh12tm1.1Cahb
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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