MP:0000063 | reduced bone density | "decreased mineral content of bone; indicator of bone strength" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:57315] |
Show
Allelic Composition: Cyp27b1tm1Star/Cyp27b1tm1Star Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Cyp27b1tm1b(EUCOMM)Hmgu/Cyp27b1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Cyp27b1tm1b(EUCOMM)Hmgu/Tcp
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MP:0000132 | thickened epiphysis | "wider than normal part of the long bones that initially develops from a distinct ossification center than the shaft" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61295] |
Show
Allelic Composition: Cyp19a1tm1Sih/Cyp19a1tm1Sih Genetic Background: involves: 129S/SvEv
|
MP:0000133 | abnormal long bone metaphysis morphology | "malformed conical section of bone between the epiphysis and diaphysis of the long bones" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:61295] |
Show
Allelic Composition: Pcyt1btm1Mkar/Pcyt1b+ Genetic Background: involves: 129S1/Sv * C57BL/6J
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MP:0000137 | abnormal vertebrae morphology | "malformed bony segment of the spinal column" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Cyb561tm1b(EUCOMM)Wtsi/Cyb561tm1b(EUCOMM)Wtsi Genetic Background: C57BL/6N-Cyb561tm1b(EUCOMM)Wtsi/H
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MP:0000149 | abnormal scapula morphology | "malformation of either or both of the large, flat bones of the back part of the shoulder" [J:13049] |
Show
Allelic Composition: Cyb561tm1b(EUCOMM)Wtsi/Cyb561tm1b(EUCOMM)Wtsi Genetic Background: C57BL/6N-Cyb561tm1b(EUCOMM)Wtsi/H
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MP:0000150 | abnormal rib morphology | "malformed bones forming the bony wall of the chest" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:50311] |
Show
Allelic Composition: Cyb561tm1b(EUCOMM)Wtsi/Cyb561tm1b(EUCOMM)Wtsi Genetic Background: C57BL/6N-Cyb561tm1b(EUCOMM)Wtsi/H
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MP:0000186 | decreased circulating HDL cholesterol level | "lower than average level of high density lipoprotein in blood; this molecule transports cholesterol to the liver for excretion in bile" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Cyp27b1tm1b(EUCOMM)Hmgu/Cyp27b1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Cyp27b1tm1b(EUCOMM)Hmgu/Tcp
|
MP:0000195 | hypocalcemia | "subnormal concentrations of calcium ions in the circulating blood " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Cyp19a1tm1Sih/Cyp19a1tm1Sih Genetic Background: involves: 129S/SvEv
Allelic Composition: Cyp27b1tm1Star/Cyp27b1tm1Star Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Cyp27b1tm1b(EUCOMM)Hmgu/Cyp27b1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Cyp27b1tm1b(EUCOMM)Hmgu/Tcp
|
MP:0000198 | hypophosphatemia | "abnormally low concentrations of phosphates in the circulating blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Cyp19a1tm1Sih/Cyp19a1tm1Sih Genetic Background: involves: 129S/SvEv
Allelic Composition: Cyp27b1tm1Star/Cyp27b1tm1Star Genetic Background: involves: 129S1/Sv * 129X1/SvJ
|
MP:0000221 | decreased WBC count | "fewer than normal numbers of WBCs" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: Cyp27b1tm1b(EUCOMM)Hmgu/Cyp27b1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Cyp27b1tm1b(EUCOMM)Hmgu/Tcp
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MP:0000438 | abnormal skull morphology | "anomalous structure or development of the cranium" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Cyb561tm1b(EUCOMM)Wtsi/Cyb561tm1b(EUCOMM)Wtsi Genetic Background: C57BL/6N-Cyb561tm1b(EUCOMM)Wtsi/H
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MP:0000552 | abnormal radius morphology | "malformation of the short bone of the lateral forearm" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Cyp27b1tm1b(EUCOMM)Hmgu/Cyp27b1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Cyp27b1tm1b(EUCOMM)Hmgu/Tcp
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MP:0000558 | abnormal tibia morphology | "atructural anomaly of the medial and larger of the two bones of the lower leg" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Cyp27b1tm1b(EUCOMM)Hmgu/Cyp27b1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Cyp27b1tm1b(EUCOMM)Hmgu/Tcp
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MP:0000559 | abnormal femur morphology | "structural anomaly of the long bone of the thigh" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Dnmt1tm1Enl/Dnmt1tm1Enl Genetic Background: involves: 129S4/SvJae * C57BL/6
Allelic Composition: Cyp27b1tm1b(EUCOMM)Hmgu/Cyp27b1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Cyp27b1tm1b(EUCOMM)Hmgu/Tcp
|
MP:0000629 | absent mammary gland | "missing milk-secreting glands of the breast" [J:18378] |
Show
Allelic Composition: Cyb561tm1b(EUCOMM)Wtsi/Cyb561tm1b(EUCOMM)Wtsi Genetic Background: C57BL/6N-Cyb561tm1b(EUCOMM)Wtsi/H
|
MP:0000692 | small spleen | "decreased spleen size" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Cyp27b1tm1b(EUCOMM)Hmgu/Cyp27b1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Cyp27b1tm1b(EUCOMM)Hmgu/Tcp
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MP:0000702 | enlarged lymph nodes | "lymph nodes of increased size" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Cyp19a1tm1Sih/Cyp19a1tm1Sih Genetic Background: involves: 129S/SvEv
|
MP:0001127 | small ovary | "reduced size of the female reproductive gland containing the germ cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782] |
Show
Allelic Composition: Cyp19a1tm1Sih/Cyp19a1tm1Sih Genetic Background: involves: 129S/SvEv
Allelic Composition: Cyp27b1tm1b(EUCOMM)Hmgu/Cyp27b1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Cyp27b1tm1b(EUCOMM)Hmgu/Tcp
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MP:0001130 | abnormal ovarian folliculogenesis | "atypical formation or failure to form the spherical ovum in the ovary" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:35782] |
Show
Allelic Composition: Cyp19a1tm1Sih/Cyp19a1tm1Sih Genetic Background: involves: 129S/SvEv
|
MP:0001132 | absent mature ovarian follicles | "failure of ovarian follicle differentiation" [J:35782] |
Show
Allelic Composition: Cyp19a1tm1Sih/Cyp19a1tm1Sih Genetic Background: involves: 129S/SvEv
|
MP:0001134 | absent corpora lutea | "missing yellow endocrine body formed in the ovary after follicle rupture" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782] |
Show
Allelic Composition: Cyp19a1tm1Sih/Cyp19a1tm1Sih Genetic Background: involves: 129S/SvEv
|
MP:0001199 | thin skin | "reduced thickness of the outer protective layer of the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49471] |
Show
Allelic Composition: Cyp27b1tm1b(EUCOMM)Hmgu/Cyp27b1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Cyp27b1tm1b(EUCOMM)Hmgu/Tcp
|
MP:0001258 | decreased body length | "decreased crown to tail distance compared to controls" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Cyb561tm1b(EUCOMM)Wtsi/Cyb561tm1b(EUCOMM)Wtsi Genetic Background: C57BL/6N-Cyb561tm1b(EUCOMM)Wtsi/H
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MP:0001262 | decreased body weight | "lower than normal average weight " [J:61295] |
Show
Allelic Composition: Cyp19a1tm1Sih/Cyp19a1tm1Sih Genetic Background: involves: 129S/SvEv
|
MP:0001265 | reduced body size | "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170] |
Show
Allelic Composition: Pcyt1btm1Mkar/Pcyt1b+ Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: Cyp27b1tm1Star/Cyp27b1tm1Star Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
MP:0001402 | hypoactivity | "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289] |
Show
Allelic Composition: Cyb561tm1b(EUCOMM)Wtsi/Cyb561tm1b(EUCOMM)Wtsi Genetic Background: C57BL/6N-Cyb561tm1b(EUCOMM)Wtsi/H
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MP:0001732 | postnatal growth retardation | "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Cyp19a1tm1Sih/Cyp19a1tm1Sih Genetic Background: involves: 129S/SvEv
Allelic Composition: Cyp27b1tm1Star/Cyp27b1tm1Star Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Cyp27b1tm1Star/Cyp27b1tm1Star Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0001926 | female infertility | "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193] |
Show
Allelic Composition: Cyp19a1tm1Sih/Cyp19a1tm1Sih Genetic Background: involves: 129S/SvEv
|
MP:0002187 | abnormal fibula morphology | "malformation of the lateral and smaller bone of the lower limb" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Cyp27b1tm1b(EUCOMM)Hmgu/Cyp27b1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Cyp27b1tm1b(EUCOMM)Hmgu/Tcp
|
MP:0002188 | small heart | "reduced size of the heart relative to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:67044] |
Show
Allelic Composition: Cyp27b1tm1b(EUCOMM)Hmgu/Cyp27b1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Cyp27b1tm1b(EUCOMM)Hmgu/Tcp
|
MP:0002637 | small uterus | "reduced size of the female muscular organ of gestation" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Cyp19a1tm1Sih/Cyp19a1tm1Sih Genetic Background: involves: 129S/SvEv
Allelic Composition: Cyp27b1tm1b(EUCOMM)Hmgu/Cyp27b1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Cyp27b1tm1b(EUCOMM)Hmgu/Tcp
|
MP:0002656 | abnormal keratinocyte differentiation | "developmental anomaly of the cells of the epidermis that produce keratin in the process of differentiating into the dead and fully keratinized cells of the stratum corneum
" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Cyp27b1tm1Star/Cyp27b1tm1Star Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
MP:0002757 | reduced vertical activity | "lesser than average time spent jumping or rearing" [J:82829, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Cyp27b1tm1b(EUCOMM)Hmgu/Cyp27b1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Cyp27b1tm1b(EUCOMM)Hmgu/Tcp
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MP:0002764 | short tibia | " reduced length of the medial and larger bone of the lower leg" [J:12736, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Cyp27b1tm1b(EUCOMM)Hmgu/Cyp27b1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Cyp27b1tm1b(EUCOMM)Hmgu/Tcp
|
MP:0002796 | impaired skin barrier function | "impaired ability of the skin to regulate water loss; frequently leads to dehydration" [J:56641] |
Show
Allelic Composition: Cyp27b1tm1Star/Cyp27b1tm1Star Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
MP:0002834 | decreased heart weight | "less than average weight of the heart compared to the average for a particular strain" [RGD:Rat Genome Database submission] |
Show
Allelic Composition: Cyp27b1tm1b(EUCOMM)Hmgu/Cyp27b1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Cyp27b1tm1b(EUCOMM)Hmgu/Tcp
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MP:0002896 | abnormal bone mineralization | "defect in the process by which minerals are deposited into bone" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Cyp27b1tm1Star/Cyp27b1tm1Star Genetic Background: involves: 129S1/Sv * 129X1/SvJ
|
MP:0002901 | hyperphosphaturia | "an increase of excretion of phosphates in the urine" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Cyp19a1tm1Sih/Cyp19a1tm1Sih Genetic Background: involves: 129S/SvEv
|
MP:0002904 | increased circulating parathyroid hormone level | "greater than expected blood concentration of this regulator of calcium and phosphorous concentration" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Cyp19a1tm1Sih/Cyp19a1tm1Sih Genetic Background: involves: 129S/SvEv
Allelic Composition: Cyp27b1tm1Star/Cyp27b1tm1Star Genetic Background: involves: 129S1/Sv * 129X1/SvJ
|
MP:0002932 | abnormal joint | "defect in the articulation point of two or more bones" [RGD:Rat Genome Database submission, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: Cyp27b1tm1b(EUCOMM)Hmgu/Cyp27b1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Cyp27b1tm1b(EUCOMM)Hmgu/Tcp
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MP:0002968 | increased circulating alkaline phosphatase level | "elevated activity of this enzyme, which hydrolyzes orthophosphoric monoesters, found in the blood" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Cyp19a1tm1Sih/Cyp19a1tm1Sih Genetic Background: involves: 129S/SvEv
Allelic Composition: Cyp27b1tm1Star/Cyp27b1tm1Star Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Cyp27b1tm1b(EUCOMM)Hmgu/Cyp27b1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Cyp27b1tm1b(EUCOMM)Hmgu/Tcp
|
MP:0002989 | small kidney | "reduced physical bulk one or both of the organs responsible for urine secretion" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Cyp27b1tm1b(EUCOMM)Hmgu/Cyp27b1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Cyp27b1tm1b(EUCOMM)Hmgu/Tcp
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MP:0003112 | enlarged parathyroid gland | |
Show
Allelic Composition: Cyp27b1tm1Star/Cyp27b1tm1Star Genetic Background: involves: 129S1/Sv * 129X1/SvJ
|
MP:0003116 | rickets | "overproduction and deficient calcification of osteoid tissue due to vitamin D deficiency; can lead to skeletal deformities, growth defects, hypocalcemia, and sometimes tetany; skeletal fractures occur frequently" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Cyp27b1tm1Star/Cyp27b1tm1Star Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Cyp27b1tm1Hfd/Cyp27b1tm1Hfd Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Cyp27b1tm1.1Star/Cyp27b1tm1.1Star Genetic Background: involves: 129S1/Sv * 129X1/SvJ
|
MP:0003131 | increased erythrocyte count | "greater number of the cells in the blood that carry oxygen, red blood cells, per unit" [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Cyp27b1tm1b(EUCOMM)Hmgu/Cyp27b1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Cyp27b1tm1b(EUCOMM)Hmgu/Tcp
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MP:0003795 | abnormal bone structure | |
Show
Allelic Composition: Cyp27b1tm1b(EUCOMM)Hmgu/Cyp27b1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Cyp27b1tm1b(EUCOMM)Hmgu/Tcp
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MP:0003961 | decreased lean body mass | "less than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator] |
Show
Allelic Composition: Cyp27b1tm1b(EUCOMM)Hmgu/Cyp27b1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Cyp27b1tm1b(EUCOMM)Hmgu/Tcp
|
MP:0004509 | abnormal pelvic girdle bone morphology | "any structural anomaly of the bones of the pelvis by which the limbs attach to the axial skeleton " [MGI:cwg "Carroll-Ann W. Goldsmith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Cyp27b1tm1b(EUCOMM)Hmgu/Cyp27b1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Cyp27b1tm1b(EUCOMM)Hmgu/Tcp
|
MP:0004819 | decreased skeletal muscle mass | "reduction in the physical bulk, or total amount of matter contained within skeletal muscle" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Cyp27b1tm1b(EUCOMM)Hmgu/Cyp27b1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Cyp27b1tm1b(EUCOMM)Hmgu/Tcp
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MP:0004924 | abnormal behavior | "anomalies in the actions, reactions, or performance of an organism in response to external or internal stimuli compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Cyp27b1tm1b(EUCOMM)Hmgu/Cyp27b1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Cyp27b1tm1b(EUCOMM)Hmgu/Tcp
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MP:0004985 | decreased osteoclast cell number | "reduced number of the bone resorpting cells that remove bone tissue by degrading the mineralized matrix" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Cyp19a1tm1Sih/Cyp19a1tm1Sih Genetic Background: involves: 129S/SvEv
|
MP:0005018 | decreased T cell number | "fewer than normal T cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Cyp19a1tm1Sih/Cyp19a1tm1Sih Genetic Background: involves: 129S/SvEv
|
MP:0005108 | abnormal ulna morphology | "malformation of the medial and larger of the two bones of the forearm" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:83132] |
Show
Allelic Composition: Cyp27b1tm1b(EUCOMM)Hmgu/Cyp27b1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Cyp27b1tm1b(EUCOMM)Hmgu/Tcp
|
MP:0005179 | decreased total circulating cholesterol level | "less than the normal concentration in the blood of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Cyp27b1tm1b(EUCOMM)Hmgu/Cyp27b1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Cyp27b1tm1b(EUCOMM)Hmgu/Tcp
|
MP:0005296 | abnormal humerus morphology | "malformation of the bone of the forelimb that articulates with the scapula above and the radius and ulna below" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Cyp27b1tm1b(EUCOMM)Hmgu/Cyp27b1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Cyp27b1tm1b(EUCOMM)Hmgu/Tcp
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MP:0005298 | abnormal clavicle morphology | "malformation of the doubly curved long bone that forms part of the shoulder girdle and articulates with the sternum and the scapula" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Cyp27b1tm1b(EUCOMM)Hmgu/Cyp27b1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Cyp27b1tm1b(EUCOMM)Hmgu/Tcp
|
MP:0005344 | increased circulating bilirubin level | "greater than the normal concentration in the blood of this yellow heme breakdown product" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:85204] |
Show
Allelic Composition: Cyp27b1tm1b(EUCOMM)Hmgu/Cyp27b1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Cyp27b1tm1b(EUCOMM)Hmgu/Tcp
|
MP:0005560 | decreased circulating glucose level | "less than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Cyp27b1tm1b(EUCOMM)Hmgu/Cyp27b1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Cyp27b1tm1b(EUCOMM)Hmgu/Tcp
|
MP:0006397 | disorganized long bone epiphyseal plate | "a lack of the regular arrangement of the cells or zones of the epiphyseal plate" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Cyp27b1tm1Star/Cyp27b1tm1Star Genetic Background: involves: 129S1/Sv * 129X1/SvJ
|
MP:0006398 | increased long bone epiphyseal plate size | "greater than the normal size of the cartilaginous center of ossification on the long bones permitting growth of the bone in both directions during development" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Cyp27b1tm1Star/Cyp27b1tm1Star Genetic Background: involves: 129S1/Sv * 129X1/SvJ
|
MP:0008489 | postnatal slow weight gain | "the weight gain over a span of postnatal developmental time is slower than controls, with or without ever attaining a similar weight to controls as adults" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Cyp27b1tm1Star/Cyp27b1tm1Star Genetic Background: involves: 129S1/Sv * 129X1/SvJ
|
MP:0008869 | anovulation | "complete failure of ovum to be released from an ovarian follicle" [MESH:C13.351.500.056.630.050, MGI:mnk "Michelle Knowlton, Mouse Genome Informatics Curator"] |
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Allelic Composition: Cyp19a1tm1Sih/Cyp19a1tm1Sih Genetic Background: involves: 129S/SvEv
|
MP:0009009 | absent estrous cycle | "failure of female animals to enter or progress through their sexual cycle" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Cyp19a1tm1Sih/Cyp19a1tm1Sih Genetic Background: involves: 129S/SvEv
|
MP:0009091 | endometrium hypoplasia | "underdevelopment or reduced size, usually due to a reduced number of cells, of the glandular mucous membrane lining of the uterine cavity that is hormonally responsive during the estrous/menstrual cycle and during pregnancy" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Cyp19a1tm1Sih/Cyp19a1tm1Sih Genetic Background: involves: 129S/SvEv
|
MP:0009445 | osteomalacia | "gradual softening and bending of the bones due to failure of osteoid tissue to calcify as a result of vitamin D deficiency or renal tubular dysfunction" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Cyp27b1tm1Star/Cyp27b1tm1Star Genetic Background: involves: 129S1/Sv * 129X1/SvJ
|
MP:0009642 | abnormal blood homeostasis | "anomaly in the processes involved in the maintenance of an internal equilibrium of various functions or chemical or protein composition of the blood" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Cyp19a1tm1Sih/Cyp19a1tm1Sih Genetic Background: involves: 129S/SvEv
Allelic Composition: Cyp27b1tm1Star/Cyp27b1tm1Star Genetic Background: involves: 129S1/Sv * 129X1/SvJ
|
MP:0010025 | decreased total body fat amount | "less than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Cyp27b1tm1b(EUCOMM)Hmgu/Cyp27b1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Cyp27b1tm1b(EUCOMM)Hmgu/Tcp
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MP:0010053 | decreased grip strength | "reduced ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"] |
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Allelic Composition: Cyp27b1tm1b(EUCOMM)Hmgu/Cyp27b1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Cyp27b1tm1b(EUCOMM)Hmgu/Tcp
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MP:0010124 | decreased bone mineral content | "reduction in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Cyp27b1tm1b(EUCOMM)Hmgu/Cyp27b1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Cyp27b1tm1b(EUCOMM)Hmgu/Tcp
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MP:0010378 | increased respiratory quotient | "increase in the ratio of the volume of carbon dioxide released to oxygen consumed by a body tissue or an organism compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Cyp27b1tm1b(EUCOMM)Hmgu/Cyp27b1tm1b(EUCOMM)Hmgu Genetic Background: C57BL/6N-Cyp27b1tm1b(EUCOMM)Hmgu/Tcp
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MP:0020137 | decreased bone mineralization | "decrease in the rate at which minerals are deposited into bone" [] |
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Allelic Composition: Cyp19a1tm1Sih/Cyp19a1tm1Sih Genetic Background: involves: 129S/SvEv
Allelic Composition: Cyp27b1tm1Star/Cyp27b1tm1Star Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Cyp27b1tm1.1Star/Cyp27b1tm1.1Star Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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