ENSMUSG00000008435


Mus musculus

Features
Gene ID: ENSMUSG00000008435
  
Biological name :Rdh13
  
Synonyms : Q8CEE7 / Rdh13 / Retinol dehydrogenase 13
  
Possible biological names infered from orthology : Q8NBN7
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: A1
Gene start: 4424770
Gene end: 4445649
  
Corresponding Affymetrix probe sets: 10559516 (MoGene1.0st)   1433799_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000114390
Ensembl peptide - ENSMUSP00000008579
Ensembl peptide - ENSMUSP00000113433
NCBI entrez gene - 108841     See in Manteia.
MGI - MGI:1918732
RefSeq - XM_011250412
RefSeq - NM_001290409
RefSeq - NM_001290411
RefSeq - NM_175372
RefSeq - XM_006539464
RefSeq Peptide - NP_001277338
RefSeq Peptide - NP_001277340
RefSeq Peptide - NP_780581
swissprot - D3YVJ8
swissprot - Q8CEE7
swissprot - A0A0R4J1N8
Ensembl - ENSMUSG00000008435
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch211-107o10.3ENSDARG00000008491Danio rerio
 si:dkey-23o4.6ENSDARG00000034577Danio rerio
 zgc:153441ENSDARG00000054797Danio rerio
 RDH13ENSG00000160439Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rdh12 / Q8BYK4 / Retinol dehydrogenase 12 / Q96NR8* / retinol dehydrogenase 12 (all-trans/9-cis/11-cis)*ENSMUSG0000002112346
Rdh11 / Q9QYF1 / Retinol dehydrogenase 11 / Q8TC12* / retinol dehydrogenase 11 (all-trans/9-cis/11-cis)*ENSMUSG0000006644146
Rdh14 / Q9ERI6 / Retinol dehydrogenase 14 / Q9HBH5*ENSMUSG0000002062145
Dhrs13 / Q5SS80 / Dehydrogenase/reductase SDR family member 13 / Q6UX07* / dehydrogenase/reductase 13*ENSMUSG0000002083440
Wwox / Q91WL8 / WW domain-containing oxidoreductase / Q9NZC7*ENSMUSG0000000463737


Protein motifs (from Interpro)
Interpro ID Name
 IPR002347  Short-chain dehydrogenase/reductase SDR
 IPR020904  Short-chain dehydrogenase/reductase, conserved site
 IPR036291  NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009644 response to high light intensity IMP
 biological_processGO:0010842 retina layer formation IMP
 biological_processGO:0042462 eye photoreceptor cell development IMP
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005739 mitochondrion IDA
 molecular_functionGO:0016491 oxidoreductase activity IEA


Pathways (from Reactome)
Pathway description
RA biosynthesis pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0003312 abnormal locomotor coordination "reduced ability of an animal to maintain skillful and effective interaction of movements while engaging in locomotor activity" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cwc27tm1Lex/Cwc27tm1Lex
Genetic Background: B6;129S5-Cwc27tm1Lex/Mmucd

 MP:0003728 abnormal photoreceptor layer "malformation/anomalous structure of the photoreceptor layer" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Ric8atm1.1Zhua/Ric8atm1.1Zhua,Tg(Nes-cre)1Kln/0
Genetic Background: involves: C57BL/6 * SJL

 MP:0003730 abnormal photoreceptor inner segments "malformation/anomalous structure of the photoreceptor layer which contains the machinery of the cell (mitochondria, golgi, endoplasmic reticulum, etc)" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Ric8atm1.1Zhua/Ric8atm1.1Zhua,Tg(Nes-cre)1Kln/0
Genetic Background: involves: C57BL/6 * SJL

 MP:0004021 abnormal rod electrophysiology "anomaly in the function of dark adapted vision mediated by the rods" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Ric8atm1.1Zhua/Ric8atm1.1Zhua,Tg(Nes-cre)1Kln/0
Genetic Background: involves: C57BL/6 * SJL

 MP:0005165 increased susceptibility to injury "greater than the normal reaction to trauma, especially that by physical means" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Ric8atm1.1Zhua/Ric8atm1.1Zhua,Tg(Nes-cre)1Kln/0
Genetic Background: involves: C57BL/6 * SJL

 MP:0008515 thin retinal outer nuclear layer "reduced thickness of the retinal layer that contains the nuclei and cell bodies of rods and cones" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ric8atm1.1Zhua/Ric8atm1.1Zhua,Tg(Nes-cre)1Kln/0
Genetic Background: involves: C57BL/6 * SJL

 MP:0008518 retinal outer nuclear layer degeneration "a retrogressive impairment or destruction of the retinal layer that contains the nuclei and cell bodies of rods and cones" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ric8atm1.1Zhua/Ric8atm1.1Zhua,Tg(Nes-cre)1Kln/0
Genetic Background: involves: C57BL/6 * SJL

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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