ENSMUSG00000008540


Mus musculus

Features
Gene ID: ENSMUSG00000008540
  
Biological name :Mgst1
  
Synonyms : Mgst1 / Microsomal glutathione S-transferase 1 / Q91VS7
  
Possible biological names infered from orthology : P10620
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: G1
Gene start: 138140316
Gene end: 138156755
  
Corresponding Affymetrix probe sets: 10542470 (MoGene1.0st)   1415897_a_at (Mouse Genome 430 2.0 Array)   1415898_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000112923
Ensembl peptide - ENSMUSP00000145306
Ensembl peptide - ENSMUSP00000144912
Ensembl peptide - ENSMUSP00000114222
Ensembl peptide - ENSMUSP00000113859
Ensembl peptide - ENSMUSP00000113257
Ensembl peptide - ENSMUSP00000008684
Ensembl peptide - ENSMUSP00000112646
NCBI entrez gene - 56615     See in Manteia.
MGI - MGI:1913850
RefSeq - XM_006506418
RefSeq - NM_019946
RefSeq Peptide - NP_064330
RefSeq Peptide - NP_001334418
swissprot - D3YVR3
swissprot - E9QJW0
swissprot - Q53ZD4
swissprot - Q91VS7
swissprot - A0A0N4SVZ0
swissprot - D3YU60
swissprot - A0A0N4SV17
Ensembl - ENSMUSG00000008540
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mgst1.1ENSDARG00000032618Danio rerio
 mgst1.2ENSDARG00000022165Danio rerio
 MGST1ENSGALG00000013098Gallus gallus
 MGST1ENSG00000008394Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ptges / Q9JM51 / Prostaglandin E synthase / O14684*ENSMUSG0000005073724


Protein motifs (from Interpro)
Interpro ID Name
 IPR001129  Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein
 IPR023352  Membrane associated eicosanoid/glutathione metabolism-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006749 glutathione metabolic process IDA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0070207 protein homotrimerization ISS
 biological_processGO:0071449 cellular response to lipid hydroperoxide IEA
 biological_processGO:0098869 cellular oxidant detoxification IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005741 mitochondrial outer membrane IEA
 cellular_componentGO:0005743 mitochondrial inner membrane IDA
 cellular_componentGO:0005783 endoplasmic reticulum ISS
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane ISS
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0004364 glutathione transferase activity IEA
 molecular_functionGO:0004602 glutathione peroxidase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Glutathione conjugation
Aflatoxin activation and detoxification
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000008540 Mgst1 / Q91VS7 / Microsomal glutathione S-transferase 1 / P10620*  / complex






 

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contact: otassy@igbmc.fr