ENSMUSG00000010080


Mus musculus

Features
Gene ID: ENSMUSG00000010080
  
Biological name :Epn3
  
Synonyms : Epn3 / Epsin-3 / Q91W69
  
Possible biological names infered from orthology : Q9H201
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: D
Gene start: 94489599
Gene end: 94499974
  
Corresponding Affymetrix probe sets: 10389990 (MoGene1.0st)   1424960_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000121390
NCBI entrez gene - 71889     See in Manteia.
MGI - MGI:1919139
RefSeq - XM_006534267
RefSeq - NM_027984
RefSeq - XM_006534266
RefSeq Peptide - NP_082260
swissprot - Q91W69
Ensembl - ENSMUSG00000010080
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 epn3aENSDARG00000078953Danio rerio
 epn3bENSDARG00000004633Danio rerio
 EPN3ENSGALG00000023279Gallus gallus
 EPN3ENSG00000049283Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Epn1 / Q80VP1 / Epsin-1 / Q9Y6I3*ENSMUSG0000003520344
Epn2 / Q8CHU3 / Epsin-2 / O95208*ENSMUSG0000000103643
Clint1 / Mus musculus clathrin interactor 1 (Clint1), transcript variant 2, mRNA. / Q14677* / clathrin interactor 1*ENSMUSG0000000616924
Enthd1 / ENTH domain containing 1 / Q8IYW4*ENSMUSG0000005043923


Protein motifs (from Interpro)
Interpro ID Name
 IPR003903  Ubiquitin interacting motif
 IPR008942  ENTH/VHS
 IPR013809  ENTH domain
 IPR027318  Epsin-3, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005905 clathrin-coated pit IDA
 cellular_componentGO:0005938 cell cortex IEA
 cellular_componentGO:0019897 extrinsic component of plasma membrane IEA
 cellular_componentGO:0030136 clathrin-coated vesicle ISO
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:1990175 EH domain binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Esr1tm1.2Awo/Esr1tm1.2Awo,Kiss1tm1.1(cre)Uboe/Kiss1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * SJL

 MP:0011967 increased or absent threshold for auditory brainstem response "increase in the value at which one or more sound frequencies or broadband clicks first elicits a recordable response generated by electrical activity of neurons in the ascending auditory system, or complete lack of a recordable response at any frequency or broadband click" [MGI:csmith]
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Allelic Composition: Clrn1tm1.1(KOMP)Vlcg/Clrn1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Clrn1tm1.1(KOMP)Vlcg/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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