MP:0000280 | thin ventricular wall | "decreased depth of the cardiac wall of the heart ventricles" [J:45302] |
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Allelic Composition: Dync2h1mmi/Dync2h1mmi,Tg(Hlxb9-GFP)1Tmj/? Genetic Background: involves: C57BL/6J * FVB/N
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MP:0000929 | open neural tube | "incomplete invagination and fusion of the neuroepithelial layer in early development" [MGI:CLS, J:53370, J:62571] |
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Allelic Composition: Dync2h1mmi/Dync2h1mmi,Tg(Hlxb9-GFP)1Tmj/? Genetic Background: involves: C57BL/6J * FVB/N
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MP:0001614 | abnormal vasculature | "anomalies in the structure of development of the network of tubes that carries blood through the body" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Dync2h1mmi/Dync2h1mmi,Tg(Hlxb9-GFP)1Tmj/? Genetic Background: involves: C57BL/6J * FVB/N
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MP:0001688 | abnormal somite development | "anomalous formation of any of the paired, metamerically arranged cell masses formed in the embryonic paraxial mesoderm" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Dync2h1mmi/Dync2h1mmi,Tg(Hlxb9-GFP)1Tmj/? Genetic Background: involves: C57BL/6J * FVB/N
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MP:0001689 | incomplete somite formation | "arrest of differentiation or patterning of the somites" [J:62882] |
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Allelic Composition: Dync2h1mmi/Dync2h1mmi,Tg(Hlxb9-GFP)1Tmj/? Genetic Background: involves: C57BL/6J * FVB/N
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MP:0001691 | abnormal somite shape | "atypical characteristic surface configuration of a segmental mass along the notochord of the developing embryo" [J:37888] |
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Allelic Composition: Dync2h1mmi/Dync2h1mmi,Tg(Hlxb9-GFP)1Tmj/? Genetic Background: involves: C57BL/6J * FVB/N
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MP:0001698 | reduced embryo size | "smaller proportions of embryo compared to littermates" [J:61790] |
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Allelic Composition: Dync2h1mmi/Dync2h1mmi,Tg(Hlxb9-GFP)1Tmj/? Genetic Background: involves: C57BL/6J * FVB/N
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MP:0001700 | abnormal embryo turning | "atypical axial rotation of the germ layers of the embryo during the primitive streak/early somite stage (Mus:E8.5-E9.5) such that the curvature of the entire trunk region is reversed and the neural ectoderm moves to the convex region and the midgut region becomes located in the concave region" [The Atlas of Mouse Development:ISBN 0-12-402035-6, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Dync2h1mmi/Dync2h1mmi,Tg(Hlxb9-GFP)1Tmj/? Genetic Background: involves: C57BL/6J * FVB/N
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MP:0001730 | embryonic growth arrest | "the cessation of development beyond a particular stage" [J:17509] |
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Allelic Composition: Dync2h1mmi/Dync2h1mmi,Tg(Hlxb9-GFP)1Tmj/? Genetic Background: involves: C57BL/6J * FVB/N
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MP:0001921 | reduced fertility | "diminished ability to produce live offspring" [J:65030] |
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Allelic Composition: Epn1tm1Ocr/Epn1tm1Ocr,Epn2tm1Ocr/Epn2+ Genetic Background: B6.129X1-Epn1tm1Ocr Epn2tm1Ocr
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MP:0002083 | premature death | "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Dync2h1mmi/Dync2h1mmi,Tg(Hlxb9-GFP)1Tmj/? Genetic Background: involves: C57BL/6J * FVB/N
Allelic Composition: Epn1tm1Ocr/Epn1tm1Ocr,Epn2tm1Ocr/Epn2+ Genetic Background: B6.129X1-Epn1tm1Ocr Epn2tm1Ocr
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MP:0002151 | abnormal neural tube morphology/development | "anomalous structure of or development of the embryonic neural tube resulting in structural anomaly" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Dync2h1mmi/Dync2h1mmi,Tg(Hlxb9-GFP)1Tmj/? Genetic Background: involves: C57BL/6J * FVB/N
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MP:0002169 | no phenotype detected | "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Dync2h1mmi/Dync2h1mmi,Tg(Hlxb9-GFP)1Tmj/? Genetic Background: involves: C57BL/6J * FVB/N
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MP:0003070 | increased vascular permeability | "greater or faster ability of the blood vessels to permit the passage of substances such as fluid, heat, or gases" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Ogg1tm1Skmi/Ogg1tm1Skmi Genetic Background: involves: 129S/SvEv * C57BL/6JJcl
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MP:0003403 | absent placental labyrinth | "malformed structure where embryonic blood vessels are surrounded by trophoblast cells and maternal blood" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:73417] |
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Allelic Composition: Dync2h1mmi/Dync2h1mmi,Tg(Hlxb9-GFP)1Tmj/? Genetic Background: involves: C57BL/6J * FVB/N
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MP:0003447 | reduced tumor growth/size | "less than expected development of tumorous growth when compared to controls" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:65383] |
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Allelic Composition: Ogg1tm1Skmi/Ogg1tm1Skmi Genetic Background: involves: 129S/SvEv * C57BL/6JJcl
Allelic Composition: Epn1tm1.1Wami/Epn1tm1.1Wami,Epn2tm1Ocr/Epn2tm1Ocr,Tg(Cdh5-cre/ERT2)CIVE23Mlia/0,Tg(TRAMP)8247Ng/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * C57BL/6J
Allelic Composition: Epn1tm1.1Wami/Epn1tm1.1Wami,Epn2tm1Ocr/Epn2tm1Ocr,Tg(Cdh5-cre)7Mlia/0 Genetic Background: involves: C57BL/6J * FVB/N
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MP:0003544 | abnormal vascular endothelial cell migration | "anomaly in the movement of endothelial cell or their precursors to the appropriate location in the body" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:95387] |
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Allelic Composition: Ogg1tm1Skmi/Ogg1tm1Skmi Genetic Background: involves: 129S/SvEv * C57BL/6JJcl
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MP:0004003 | abnormal vascular endothelial cell physiology | "anomaly in the function of the cells that line the vasculature" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Ogg1tm1Skmi/Ogg1tm1Skmi Genetic Background: involves: 129S/SvEv * C57BL/6JJcl
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MP:0004076 | abnormal vitelline vascular remodelling | "anomaly in the conversion of the primary (honeycomb-like) vascular plexus of the yolk sac into a mature vascular network" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Dync2h1mmi/Dync2h1mmi,Tg(Hlxb9-GFP)1Tmj/? Genetic Background: involves: C57BL/6J * FVB/N
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MP:0004502 | decreased incidence of chemically-induced tumors | "lower than normal frequency of tumor incidence induced by one or more chemical carcinogens or mutagens" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ogg1tm1Skmi/Ogg1tm1Skmi Genetic Background: involves: 129S/SvEv * C57BL/6JJcl
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MP:0004950 | abnormal brain vasculature | "any structural anomaly of the blood vessel network of the brain" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Dync2h1mmi/Dync2h1mmi,Tg(Hlxb9-GFP)1Tmj/? Genetic Background: involves: C57BL/6J * FVB/N
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MP:0005222 | abnormal somite size | "atypical size of any of the segmental masses along the notochord of the developing embryo" [J:72325] |
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Allelic Composition: Dync2h1mmi/Dync2h1mmi,Tg(Hlxb9-GFP)1Tmj/? Genetic Background: involves: C57BL/6J * FVB/N
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MP:0008489 | postnatal slow weight gain | "the weight gain over a span of postnatal developmental time is slower than controls, with or without ever attaining a similar weight to controls as adults" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Dync2h1mmi/Dync2h1mmi,Tg(Hlxb9-GFP)1Tmj/? Genetic Background: involves: C57BL/6J * FVB/N
Allelic Composition: Epn1tm1Ocr/Epn1tm1Ocr,Epn2tm1Ocr/Epn2+ Genetic Background: B6.129X1-Epn1tm1Ocr Epn2tm1Ocr
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MP:0008770 | decreased survivor rate | "a smaller percentage of organisms than expected survive to adulthood and have a lifespan similar to controls" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Dync2h1mmi/Dync2h1mmi,Tg(Hlxb9-GFP)1Tmj/? Genetic Background: involves: C57BL/6J * FVB/N
Allelic Composition: Epn1tm1Ocr/Epn1tm1Ocr,Epn2tm1Ocr/Epn2+ Genetic Background: B6.129X1-Epn1tm1Ocr Epn2tm1Ocr
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MP:0009577 | abnormal developmental vascular remodeling | "any anomaly in the process by which existing vessels are reorganized during development" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Dync2h1mmi/Dync2h1mmi,Tg(Hlxb9-GFP)1Tmj/? Genetic Background: involves: C57BL/6J * FVB/N
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MP:0009764 | decreased sensitivity to induced morbidity/mortality | "increase in the amount of an external agent required to cause death or diseased state" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ogg1tm1Skmi/Ogg1tm1Skmi Genetic Background: involves: 129S/SvEv * C57BL/6JJcl
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MP:0010144 | abnormal tumor vascularization | "aberrant process of blood vessel formation and the subsequent remodeling process within and/or around tumors" [MGI:mnk "Michelle Knowlton, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ogg1tm1Skmi/Ogg1tm1Skmi Genetic Background: involves: 129S/SvEv * C57BL/6JJcl
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MP:0010769 | abnormal survival | "deviation from the expected viability or life span of an organism" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Epn1tm1.1Wami/Epn1tm1.1Wami,Epn2tm1Ocr/Epn2tm1Ocr,Tg(Cdh5-cre/ERT2)CIVE23Mlia/0,Tg(TRAMP)8247Ng/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * C57BL/6J
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MP:0011098 | complete embryonic lethality during organogenesis | "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith] |
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Allelic Composition: Dync2h1mmi/Dync2h1mmi,Tg(Hlxb9-GFP)1Tmj/? Genetic Background: involves: C57BL/6J * FVB/N
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MP:0020161 | increased vascular endothelial cell proliferation | "increase in the expansion rate of any vascular endothelial cell population by cell division" [ORCID: orcid.org/0000-0003-4606-0597] |
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Allelic Composition: Ogg1tm1Skmi/Ogg1tm1Skmi Genetic Background: involves: 129S/SvEv * C57BL/6JJcl
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