ENSMUSG00000050148


Mus musculus

Features
Gene ID: ENSMUSG00000050148
  
Biological name :Ubqln2
  
Synonyms : Q9QZM0 / ubiquilin 2 / Ubqln2
  
Possible biological names infered from orthology : Q9UHD9
  
Species: Mus musculus
  
Chr. number: X
Strand: 1
Band: F3
Gene start: 153498227
Gene end: 153501570
  
Corresponding Affymetrix probe sets: 10602716 (MoGene1.0st)   1420844_at (Mouse Genome 430 2.0 Array)   1450021_at (Mouse Genome 430 2.0 Array)   1456627_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000056888
NCBI entrez gene - 54609     See in Manteia.
MGI - MGI:1860283
RefSeq - NM_018798
RefSeq Peptide - NP_061268
swissprot - Q9QZM0
Ensembl - ENSMUSG00000050148
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000012585Gallus gallus
 Q9UHD9ENSG00000188021Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8R317 / Ubqln1 / ubiquilin 1 / Q9UMX0*ENSMUSG0000000531268
Q99NB8 / Ubqln4 / ubiquilin 4 / Q9NRR5*ENSMUSG0000000860454
Q8C5U9 / Ubqln3 / ubiquilin 3 / Q9H347*ENSMUSG0000005161840
Q14DL0 / Ubqlnl / ubiquilin-like / Q8IYU4*ENSMUSG0000005143730
Ubqln5 / ubiquilin 5ENSMUSG0000005564326


Protein motifs (from Interpro)
Interpro ID Name
 IPR000626  Ubiquitin domain
 IPR006636  Heat shock chaperonin-binding
 IPR009060  UBA-like superfamily
 IPR015496  Ubiquilin
 IPR015940  Ubiquitin-associated domain
 IPR016024  Armadillo-type fold
 IPR028430  Ubiquilin-2
 IPR029071  Ubiquitin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0016241 regulation of macroautophagy IEA
 biological_processGO:0030433 ubiquitin-dependent ERAD pathway IEA
 biological_processGO:1900186 negative regulation of clathrin-dependent endocytosis IEA
 biological_processGO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process IEA
 biological_processGO:1904021 negative regulation of G-protein coupled receptor internalization IEA
 biological_processGO:2000785 regulation of autophagosome assembly IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005776 autophagosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Cargo recognition for clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000001036 Epn2 / Q8CHU3 / Epsin-2 / O95208*  / reaction / complex
 ENSMUSG00000028552 Eps15 / P42567 / Epidermal growth factor receptor substrate 15 / P42566* / epidermal growth factor receptor pathway substrate 15*  / complex / reaction
 ENSMUSG00000035203 Epn1 / Q80VP1 / Epsin-1 / Q9Y6I3*  / reaction / complex






 

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