ENSDARG00000010411


Danio rerio

Features
Gene ID: ENSDARG00000010411
  
Biological name :epn1
  
Synonyms : epn1 / epsin 1
  
Possible biological names infered from orthology : Q80VP1 / Q9Y6I3
  
Species: Danio rerio
  
Chr. number: 16
Strand: 1
Band:
Gene start: 12730311
Gene end: 12756528
  
Corresponding Affymetrix probe sets: Dr.7146.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000123038
Ensembl peptide - ENSDARP00000138794
Ensembl peptide - ENSDARP00000105117
NCBI entrez gene - 406671     See in Manteia.
RefSeq - NM_001328116
RefSeq - XM_009292094
RefSeq Peptide - NP_001315045
swissprot - F1Q5Z9
swissprot - A0A0R4IUB6
swissprot - F1QH06
ZFIN ID - ZDB-GENE-040426-2680
Ensembl - ENSDARG00000010411
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 EPN1ENSG00000063245Homo sapiens
 Epn1ENSMUSG00000035203Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
epn2 / epsin 2 / O95208* / Q8CHU3*ENSDARG0000000837742
epn3a / epsin 3a / EPN3* / Q9H201* / Q91W69* / epsin 3*ENSDARG0000007895339
epn3b / epsin 3b / EPN3* / Q9H201* / Q91W69* / epsin 3*ENSDARG0000000463335
zgc:194578ENSDARG0000007984728
clint1a / clathrin interactor 1a / CLINT1* / Q14677* / clathrin interactor 1* / Mus musculus clathrin interactor 1 (Clint1), transcript variant 2, mRNA.*ENSDARG0000002553520
clint1b / clathrin interactor 1b / CLINT1* / Q14677* / clathrin interactor 1*ENSDARG0000008991419


Protein motifs (from Interpro)
Interpro ID Name
 IPR003903  Ubiquitin interacting motif
 IPR008942  ENTH/VHS
 IPR013809  ENTH domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
EGFR downregulation
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000052739 egf / epidermal growth factor / P01132* / P01133* / Mus musculus epidermal growth factor (Egf), transcript variant 3, mRNA.*  / complex / reaction
 ENSDARG00000038059 grb2b / growth factor receptor-bound protein 2b / GRB2* / Q60631* / P62993* / growth factor receptor bound protein 2*  / complex / reaction
 ENSDARG00000076768 reps2 / RALBP1 associated Eps domain containing 2 / Q8NFH8*  / reaction / complex
 ENSDARG00000105276 grb2a / growth factor receptor-bound protein 2a / GRB2* / Q60631* / P62993* / growth factor receptor bound protein 2*  / reaction / complex






 

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