ENSDARG00000008377


Danio rerio

Features
Gene ID: ENSDARG00000008377
  
Biological name :epn2
  
Synonyms : epn2 / epsin 2
  
Possible biological names infered from orthology : O95208 / Q8CHU3
  
Species: Danio rerio
  
Chr. number: 3
Strand: 1
Band:
Gene start: 39656188
Gene end: 39690218
  
Corresponding Affymetrix probe sets: Dr.25123.1.A1_at (Zebrafish Array)   Dr.25123.2.S1_at (Zebrafish Array)   Dr.5456.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000153575
Ensembl peptide - ENSDARP00000156149
Ensembl peptide - ENSDARP00000127680
Ensembl peptide - ENSDARP00000128983
Ensembl peptide - ENSDARP00000146318
Ensembl peptide - ENSDARP00000153173
NCBI entrez gene - 560542     See in Manteia.
RefSeq - XM_009299683
RefSeq - XM_681373
swissprot - E7EYW2
swissprot - X1WBT8
ZFIN ID - ZDB-GENE-071212-1
Ensembl - ENSDARG00000008377
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 EPN2ENSGALG00000035919Gallus gallus
 EPN2ENSG00000072134Homo sapiens
 Epn2ENSMUSG00000001036Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
epn1 / epsin 1 / Q80VP1* / Q9Y6I3*ENSDARG0000001041146
epn3a / epsin 3a / EPN3* / Q9H201* / Q91W69* / epsin 3*ENSDARG0000007895343
epn3b / epsin 3b / EPN3* / Q9H201* / Q91W69* / epsin 3*ENSDARG0000000463340
zgc:194578ENSDARG0000007984729
clint1b / clathrin interactor 1b / CLINT1* / Q14677* / clathrin interactor 1*ENSDARG0000008991423
clint1a / clathrin interactor 1a / CLINT1* / Q14677* / clathrin interactor 1* / Mus musculus clathrin interactor 1 (Clint1), transcript variant 2, mRNA.*ENSDARG0000002553523


Protein motifs (from Interpro)
Interpro ID Name
 IPR003903  Ubiquitin interacting motif
 IPR008942  ENTH/VHS
 IPR013809  ENTH domain
 IPR027319  Epsin-2, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006897 endocytosis IEA
 cellular_componentGO:0030128 clathrin coat of endocytic vesicle IEA


Pathways (from Reactome)
Pathway description
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000052739 egf / epidermal growth factor / P01132* / P01133* / Mus musculus epidermal growth factor (Egf), transcript variant 3, mRNA.*  / reaction / complex
 ENSDARG00000038059 grb2b / growth factor receptor-bound protein 2b / GRB2* / Q60631* / P62993* / growth factor receptor bound protein 2*  / reaction / complex
 ENSDARG00000076768 reps2 / RALBP1 associated Eps domain containing 2 / Q8NFH8*  / complex / reaction
 ENSDARG00000105276 grb2a / growth factor receptor-bound protein 2a / GRB2* / Q60631* / P62993* / growth factor receptor bound protein 2*  / reaction / complex






 

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