ENSGALG00000035919


Gallus gallus

Features
Gene ID: ENSGALG00000035919
  
Biological name :EPN2
  
Synonyms : EPN2 / epsin-2
  
Possible biological names infered from orthology : O95208 / Q8CHU3
  
Species: Gallus gallus
  
Chr. number: 14
Strand: 1
Band:
Gene start: 5208548
Gene end: 5245591
  
Corresponding Affymetrix probe sets: Gga.16726.1.S1_at (Chicken Array)   Gga.16726.1.S1_s_at (Chicken Array)   GgaAffx.11530.1.S1_at (Chicken Array)   GgaAffx.20180.1.S1_s_at (Chicken Array)   GgaAffx.26415.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000046068
NCBI entrez gene - 416524     See in Manteia.
RefSeq - XM_015294190
RefSeq - NM_001012788
RefSeq - XM_015294188
RefSeq - XM_015294189
RefSeq - XM_015294184
RefSeq - XM_015294185
RefSeq - XM_015294186
RefSeq - XM_015294187
RefSeq Peptide - NP_001012806
swissprot - A0A1D5P094
Ensembl - ENSGALG00000035919
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 epn2ENSDARG00000008377Danio rerio
 EPN2ENSG00000072134Homo sapiens
 Epn2ENSMUSG00000001036Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
EPN3 / epsin 3 / Q91W69* / Q9H201*ENSGALG0000002327941
CLINT1 / clathrin interactor 1 / Q14677* / Mus musculus clathrin interactor 1 (Clint1), transcript variant 2, mRNA.*ENSGALG0000000370226


Protein motifs (from Interpro)
Interpro ID Name
 IPR003903  Ubiquitin interacting motif
 IPR008942  ENTH/VHS
 IPR013809  ENTH domain
 IPR027319  Epsin-2, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway IEA
 biological_processGO:0045747 positive regulation of Notch signaling pathway IEA
 biological_processGO:1903671 negative regulation of sprouting angiogenesis IEA
 cellular_componentGO:0030128 clathrin coat of endocytic vesicle IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0045296 cadherin binding IEA


Pathways (from Reactome)
Pathway description
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000008016 GRB2 / growth factor receptor-bound protein 2 / P62993* / Q60631*  / complex / reaction
 ENSGALG00000012585 Q8R317* / Q9QZM0* / Q9UHD9* / Q9UMX0* / UBQLN2* / UBQLN1* / ubiquilin 1* / ubiquilin 2*  / complex / reaction
 ENSGALG00000037716 UBA52 / ubiquitin A-52 residue ribosomal protein fusion product 1 / P62984* / P62987* / Gm5239* / Gm11808* / predicted gene 11808*  / reaction / complex
 ENSGALG00000038089 EGFR / epidermal growth factor receptor / P00533* / Q01279*  / reaction / complex
 ENSGALG00000036790 P79781 / RPS27A / Ubiquitin-40S ribosomal protein S27a Ubiquitin 40S ribosomal protein S27a / P62983* / P62979* / AL136454.1* / ribosomal protein S27a*  / complex / reaction






 

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