ENSDARG00000076768


Danio rerio

Features
Gene ID: ENSDARG00000076768
  
Biological name :reps2
  
Synonyms : RALBP1 associated Eps domain containing 2 / reps2
  
Possible biological names infered from orthology : Q8NFH8 / RALBP1 associated Eps domain containing protein 2
  
Species: Danio rerio
  
Chr. number: 23
Strand: 1
Band:
Gene start: 40951443
Gene end: 40996780
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000098730
swissprot - E7FBC4
ZFIN ID - ZDB-GENE-130415-3
Ensembl - ENSDARG00000076768
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 REPS2ENSGALG00000016545Gallus gallus
 REPS2ENSG00000169891Homo sapiens
 Reps2ENSMUSG00000040855Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
reps1 / RALBP1 associated Eps domain containing 1 / O54916* / Q96D71* / RalBP1-associated Eps domain-containing protein 1 *ENSDARG0000000287738
itsn1 / intersectin 1 (SH3 domain protein) / Q15811* / Q9Z0R4* / intersectin 1*ENSDARG0000000008623
itsn2a / intersectin 2a / ITSN2* / Q9NZM3* / intersectin 2*ENSDARG0000000016120
itsn2b / intersectin 2b / ITSN2* / Q9NZM3* / intersectin 2*ENSDARG0000005497318
eps15 / epidermal growth factor receptor pathway substrate 15 / P42566* / P42567* / Epidermal growth factor receptor substrate 15 *ENSDARG0000007821618
eps15l1a / epidermal growth factor receptor pathway substrate 15-like 1a / Q9UBC2* / Q60902* / EPS15L1* / Epidermal growth factor receptor substrate 15-like 1 * / epidermal growth factor re...ENSDARG0000004267018
ehd4 / EH-domain containing 4 / Q9EQP2* / Q9H223* / EH domain-containing protein 4 *ENSDARG000000543028
ehd2a / EH-domain containing 2a / EHD2* / Q9NZN4* / Q8BH64* / EH domain containing 2* / EH domain-containing protein 2 *ENSDARG000000351378
CABZ01066725.1 / Q9UBC2* / EPS15L1* / epidermal growth factor receptor pathway substrate 15 like 1*ENSDARG000001007008
ehd2b / EH-domain containing 2b / EHD2* / Q9NZN4* / Q8BH64* / EH domain containing 2* / EH domain-containing protein 2 *ENSDARG000000403627
ehd1b / EH-domain containing 1b / EHD1* / Q9WVK4* / Q9H4M9* / EH domain containing 1* / EH domain-containing protein 1 *ENSDARG000000147937
ehd1a / EH-domain containing 1a / EHD1* / Q9WVK4* / Q9H4M9* / EH domain containing 1* / EH domain-containing protein 1 *ENSDARG000000988537
ehd3 / EH-domain containing 3 / Q9NZN3*ENSDARG000000078696
srl / sarcalumenin / Q86TD4*ENSDARG000001045874
CABZ01072309.1 / SRL* / Q86TD4* / sarcalumenin*ENSDARG000001129593
LO017845.1 / REPS2* / Q8NFH8* / RALBP1 associated Eps domain containing 2*ENSDARG000001150130


Protein motifs (from Interpro)
Interpro ID Name
 IPR000261  EH domain
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 molecular_functionGO:0005509 calcium ion binding IEA


Pathways (from Reactome)
Pathway description
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000105276 grb2a / growth factor receptor-bound protein 2a / GRB2* / Q60631* / P62993* / growth factor receptor bound protein 2*  / complex
 ENSDARG00000078216 eps15 / epidermal growth factor receptor pathway substrate 15 / P42566* / P42567* / Epidermal growth factor receptor substrate 15 *  / complex / reaction
 ENSDARG00000038059 grb2b / growth factor receptor-bound protein 2b / GRB2* / Q60631* / P62993* / growth factor receptor bound protein 2*  / complex
 ENSDARG00000052739 egf / epidermal growth factor / P01132* / P01133* / Mus musculus epidermal growth factor (Egf), transcript variant 3, mRNA.*  / complex
 ENSDARG00000008377 epn2 / epsin 2 / O95208* / Q8CHU3*  / reaction / complex
 ENSDARG00000010411 epn1 / epsin 1 / Q80VP1* / Q9Y6I3*  / complex / reaction






 

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