ENSDARG00000040362


Danio rerio

Features
Gene ID: ENSDARG00000040362
  
Biological name :ehd2b
  
Synonyms : ehd2b / EH-domain containing 2b
  
Possible biological names infered from orthology : EHD2 / EH domain containing 2 / EH domain-containing protein 2 / Q8BH64 / Q9NZN4
  
Species: Danio rerio
  
Chr. number: 18
Strand: 1
Band:
Gene start: 44649804
Gene end: 44663244
  
Corresponding Affymetrix probe sets: Dr.6603.1.A1_at (Zebrafish Array)   NM_200063_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000059062
NCBI entrez gene - 337401     See in Manteia.
RefSeq - NM_200063
RefSeq Peptide - NP_956357
swissprot - Q6P3J7
ZFIN ID - ZDB-GENE-030131-9347
Ensembl - ENSDARG00000040362
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 EHD2ENSG00000024422Homo sapiens
 Ehd2ENSMUSG00000074364Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ehd2a / EH-domain containing 2a / EHD2* / Q9NZN4* / Q8BH64* / EH domain containing 2* / EH domain-containing protein 2 *ENSDARG0000003513772
ehd3 / EH-domain containing 3 / Q9NZN3*ENSDARG0000000786970
ehd1b / EH-domain containing 1b / EHD1* / Q9WVK4* / Q9H4M9* / EH domain containing 1* / EH domain-containing protein 1 *ENSDARG0000001479369
ehd1a / EH-domain containing 1a / EHD1* / Q9WVK4* / Q9H4M9* / EH domain containing 1* / EH domain-containing protein 1 *ENSDARG0000009885368
ehd4 / EH-domain containing 4 / Q9EQP2* / Q9H223* / EH domain-containing protein 4 *ENSDARG0000005430265
srl / sarcalumenin / Q86TD4*ENSDARG0000010458724
CABZ01072309.1 / SRL* / Q86TD4* / sarcalumenin*ENSDARG0000011295921
itsn1 / intersectin 1 (SH3 domain protein) / Q15811* / Q9Z0R4* / intersectin 1*ENSDARG0000000008616
itsn2a / intersectin 2a / ITSN2* / Q9NZM3* / intersectin 2*ENSDARG0000000016115
eps15l1a / epidermal growth factor receptor pathway substrate 15-like 1a / Q9UBC2* / Q60902* / EPS15L1* / Epidermal growth factor receptor substrate 15-like 1 * / epidermal growth factor re...ENSDARG0000004267015
itsn2b / intersectin 2b / ITSN2* / Q9NZM3* / intersectin 2*ENSDARG0000005497315
eps15 / epidermal growth factor receptor pathway substrate 15 / P42566* / P42567* / Epidermal growth factor receptor substrate 15 *ENSDARG0000007821614
reps1 / RALBP1 associated Eps domain containing 1 / O54916* / Q96D71* / RalBP1-associated Eps domain-containing protein 1 *ENSDARG0000000287710
CABZ01066725.1 / Q9UBC2* / EPS15L1* / epidermal growth factor receptor pathway substrate 15 like 1*ENSDARG000001007009
reps2 / RALBP1 associated Eps domain containing 2 / Q8NFH8*ENSDARG000000767685
LO017845.1 / REPS2* / Q8NFH8* / RALBP1 associated Eps domain containing 2*ENSDARG000001150130


Protein motifs (from Interpro)
Interpro ID Name
 IPR000261  EH domain
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site
 IPR022812  Dynamin superfamily
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR029945  EH domain-containing protein 2
 IPR030381  Dynamin-type guanine nucleotide-binding (G) domain
 IPR031692  EH domain-containing protein, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030036 actin cytoskeleton organization IEA
 biological_processGO:0032456 endocytic recycling IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
Factors involved in megakaryocyte development and platelet production


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000078215 rbsn / rabenosyn, RAB effector / Q80Y56* / Q9H1K0* / Rabenosyn-5 *  / complex / reaction






 

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