ENSDARG00000098853


Danio rerio

Features
Gene ID: ENSDARG00000098853
  
Biological name :ehd1a
  
Synonyms : ehd1a / EH-domain containing 1a
  
Possible biological names infered from orthology : EHD1 / EH domain containing 1 / EH domain-containing protein 1 / Q9H4M9 / Q9WVK4
  
Species: Danio rerio
  
Chr. number: 14
Strand: -1
Band:
Gene start: 45434680
Gene end: 45464112
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000142374
NCBI entrez gene - 405810     See in Manteia.
swissprot - Q6NY81
ZFIN ID - ZDB-GENE-040426-2518
Ensembl - ENSDARG00000098853
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 EHD1ENSG00000110047Homo sapiens
 Ehd1ENSMUSG00000024772Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ehd1b / EH-domain containing 1b / EHD1* / Q9WVK4* / Q9H4M9* / EH domain containing 1* / EH domain-containing protein 1 *ENSDARG0000001479388
ehd3 / EH-domain containing 3 / Q9NZN3*ENSDARG0000000786983
ehd4 / EH-domain containing 4 / Q9EQP2* / Q9H223* / EH domain-containing protein 4 *ENSDARG0000005430274
ehd2b / EH-domain containing 2b / EHD2* / Q9NZN4* / Q8BH64* / EH domain containing 2* / EH domain-containing protein 2 *ENSDARG0000004036269
ehd2a / EH-domain containing 2a / EHD2* / Q9NZN4* / Q8BH64* / EH domain containing 2* / EH domain-containing protein 2 *ENSDARG0000003513762
srl / sarcalumenin / Q86TD4*ENSDARG0000010458723
CABZ01072309.1 / SRL* / Q86TD4* / sarcalumenin*ENSDARG0000011295921
itsn1 / intersectin 1 (SH3 domain protein) / Q15811* / Q9Z0R4* / intersectin 1*ENSDARG0000000008616
itsn2a / intersectin 2a / ITSN2* / Q9NZM3* / intersectin 2*ENSDARG0000000016116
eps15l1a / epidermal growth factor receptor pathway substrate 15-like 1a / Q9UBC2* / Q60902* / EPS15L1* / Epidermal growth factor receptor substrate 15-like 1 * / epidermal growth factor re...ENSDARG0000004267015
itsn2b / intersectin 2b / ITSN2* / Q9NZM3* / intersectin 2*ENSDARG0000005497315
eps15 / epidermal growth factor receptor pathway substrate 15 / P42566* / P42567* / Epidermal growth factor receptor substrate 15 *ENSDARG0000007821614
reps1 / RALBP1 associated Eps domain containing 1 / O54916* / Q96D71* / RalBP1-associated Eps domain-containing protein 1 *ENSDARG0000000287710
CABZ01066725.1 / Q9UBC2* / EPS15L1* / epidermal growth factor receptor pathway substrate 15 like 1*ENSDARG000001007009
reps2 / RALBP1 associated Eps domain containing 2 / Q8NFH8*ENSDARG000000767685
LO017845.1 / REPS2* / Q8NFH8* / RALBP1 associated Eps domain containing 2*ENSDARG000001150131


Protein motifs (from Interpro)
Interpro ID Name
 IPR000261  EH domain
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site
 IPR022812  Dynamin superfamily
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR030381  Dynamin-type guanine nucleotide-binding (G) domain
 IPR031692  EH domain-containing protein, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0060271 cilium assembly IMP
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
Factors involved in megakaryocyte development and platelet production


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000051 otic vesicle otic vesicle kinocilium absent , abnormal
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 ZFA:0001466 photoreceptor outer segment layer photoreceptor outer segment layer decreased amount , abnormal
Show

 ZFA:0009367 neuromast hair cell neuromast hair cell cilium morphology , abnormal
neuromast hair cell cilium decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000078215 rbsn / rabenosyn, RAB effector / Q80Y56* / Q9H1K0* / Rabenosyn-5 *  / complex / reaction






 

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