ENSMUSG00000019261


Mus musculus

Features
Gene ID: ENSMUSG00000019261
  
Biological name :Map1s
  
Synonyms : Map1s / Microtubule-associated protein 1S MAP1S heavy chain MAP1S light chain / Q8C052
  
Possible biological names infered from orthology : microtubule associated protein 1S / Q66K74
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: B3.3
Gene start: 70905932
Gene end: 70917529
  
Corresponding Affymetrix probe sets: 10572516 (MoGene1.0st)   1454732_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000019405
Ensembl peptide - ENSMUSP00000148822
Ensembl peptide - ENSMUSP00000148773
Ensembl peptide - ENSMUSP00000148752
Ensembl peptide - ENSMUSP00000148554
NCBI entrez gene - 270058     See in Manteia.
MGI - MGI:2443304
RefSeq - XM_011242305
RefSeq - NM_173013
RefSeq Peptide - NP_766601
swissprot - A0A1D5RLY6
swissprot - A0A1D5RMG7
swissprot - A0A1D5RML0
swissprot - Q8C052
swissprot - A0A1D5RMF1
Ensembl - ENSMUSG00000019261
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 map1saENSDARG00000060805Danio rerio
 map1sbENSDARG00000060326Danio rerio
 MAP1SENSGALG00000039108Gallus gallus
 MAP1SENSG00000130479Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Map1b / P14873 / microtubule-associated protein 1B / P46821*ENSMUSG0000005272742
Map1a / Q9QYR6 / Microtubule-associated protein 1A MAP1A heavy chain MAP1 light chain LC2 / P78559* / microtubule associated protein 1A*ENSMUSG0000002725440


Protein motifs (from Interpro)
Interpro ID Name
 IPR026074  Microtubule associated protein 1
 IPR027322  Microtubule-associated protein 1S
 IPR036866  Ribonuclease Z/Hydroxyacylglutathione hydrolase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000226 microtubule cytoskeleton organization IEA
 biological_processGO:0001578 microtubule bundle formation IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007399 nervous system development IEP
 biological_processGO:0007420 brain development IEP
 biological_processGO:0010848 regulation of chromatin disassembly ISS
 biological_processGO:0048812 neuron projection morphogenesis ISS
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005819 spindle IEA
 cellular_componentGO:0005829 cytosol ISS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0015630 microtubule cytoskeleton IDA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030425 dendrite IDA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043025 neuronal cell body IDA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0003677 DNA binding ISS
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0015631 tubulin binding IEA
 molecular_functionGO:0042802 identical protein binding IDA
 molecular_functionGO:0048487 beta-tubulin binding IEA
 molecular_functionGO:0051015 actin filament binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000278 abnormal myocardial fiber morphology "malformed or poorly developed cardiac muscle fibers, the multinucleated muscle cells of the heart" [J:18048]
Show

Allelic Composition: Pkd2lrm4/Pkd2lrm4
Genetic Background: C3.CAnN-Pkd2lrm4

 MP:0008260 abnormal autophagy "abnormal catabolic process involving the degradation of a cell s own components through the lysosomal machinery" [MGI:honda "Hiraoki Onda, Mouse Genome Informatics Curator"]
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Allelic Composition: Pkd2lrm4/Pkd2lrm4
Genetic Background: C3.CAnN-Pkd2lrm4

Allelic Composition: Map1stm1.1Lliu/Map1stm1.1Lliu,Tg(CAG-EGFP/Map1lc3b)53Nmz/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6 * C57BL/6NCrj

 MP:0009763 increased sensitivity to induced morbidity/mortality "decrease in the amount of an external agent required to cause death or diseased state" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Map1stm1.1Lliu/Map1stm1.1Lliu,Tg(CAG-EGFP/Map1lc3b)53Nmz/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6 * C57BL/6NCrj

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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