MP:0000422 | delayed hair appearance | "late onset of the first appearance of the fur" [J:17792] |
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Allelic Composition: Liftm1Cgre/Liftm1Cgre Genetic Background: involves: MF1
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MP:0000556 | abnormal hindlimb morphology | "malformation of the entire posterior extremities" [MGI:tc] |
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Allelic Composition: Map1btm1Rak/Map1b+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
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MP:0000745 | tremors | "repetitive, cyclical movements of the body or a body part; usually involuntary, but can also manifest in response to an attempt at movement" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Map1btm1Rak/Map1b+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
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MP:0000755 | hindlimb paralysis | "loss of power of voluntary movement in the muscles of the hindlimb through injury or disease of it or its nerve supply" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Map1btm1Rak/Map1b+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
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MP:0000780 | abnormal corpus callosum morphology | "malformation or absence of a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres; it consists of contralateral axon projections that provides communications between the right and left cerebral hemispheres" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Gpx1tm1Ysh/Gpx1tm1Ysh Genetic Background: B6.129-Gpx1tm1Ysh
Allelic Composition: Map1btm1Noh/Map1btm1Noh,Map2tm1Noh/Map2tm1Noh Genetic Background: involves: C57BL/6
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MP:0000781 | reduced size of corpus callosum | "smaller commissural plate interconnecting the cortical hemispheres of the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:38857] |
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Allelic Composition: Liftm1Cgre/Liftm1Cgre Genetic Background: involves: MF1
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MP:0000788 | abnormal cerebral cortex morphology | "malformed gray cellular mantle covering the surface of the brain" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:38857] |
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Allelic Composition: Gpx1tm1Ysh/Gpx1tm1Ysh Genetic Background: B6.129-Gpx1tm1Ysh
Allelic Composition: Map1btm1Noh/Map1btm1Noh,Map2tm1Noh/Map2tm1Noh Genetic Background: involves: C57BL/6
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MP:0000790 | abnormal stratification in cerebral cortex | "abnormal formation or pattern of the layers of the cerebral cortex " [J:64289, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Map1btm1Noh/Map1btm1Noh,Map2tm1Noh/Map2tm1Noh Genetic Background: involves: C57BL/6
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MP:0000794 | abnormal parietal lobe morphology | "malformation or absence of the upper central part of the cerebral hemisphere" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Map1btm1Prop/Map1btm1Prop Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0000807 | abnormal hippocampus morphology | "absent or malformed deep lying structure of the cerebrum involved with memory storage and spatial navigation" [The Atlas of Mouse Development:ISBN 0-12-402035-6, MGI:Cls, J:38857] |
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Allelic Composition: Gpx1tm1Ysh/Gpx1tm1Ysh Genetic Background: B6.129-Gpx1tm1Ysh
Allelic Composition: Map1btm1Prop/Map1btm1Prop Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Map1btm1Rak/Map1b+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
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MP:0000812 | abnormal dentate gyrus morphology | "absence or malformation of one of two interlocking gyri of the hippocampus that contains granule cells, which project to the pyramidal cells and interneurons of the CA3 region of the ammon gyrus" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:38857] |
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Allelic Composition: Gpx1tm1Ysh/Gpx1tm1Ysh Genetic Background: B6.129-Gpx1tm1Ysh
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MP:0000813 | abnormal hippocampal laminar structure | "malformed or missing layers of the laminar structure of the hippocampus" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:38857] |
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Allelic Composition: Map1btm1Noh/Map1btm1Noh,Map2tm1Noh/Map2tm1Noh Genetic Background: involves: C57BL/6
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MP:0000819 | abnormal olfactory bulb morphology | "malformation or absence of the forebrain region that coordinates neuronal signaling involved in the perception of smell; it receives input from the sensory neurons and outputs to the olfactory cortex" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, Principles of Neural Science:ISBN 0-8385-8034-3, J:16461] |
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Allelic Composition: Gpx1tm1Ysh/Gpx1tm1Ysh Genetic Background: B6.129-Gpx1tm1Ysh
Allelic Composition: Map1btm1Rak/Map1b+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
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MP:0000849 | abnormal cerebellum morphology | "any malformation or absence of the part of the metencephalon that lies in the posterior cranial fossa dorsal to the pons and medulla that is concerned with the coordination of movement and learning of motor skills" [J:50311, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3] |
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Allelic Composition: Gpx1tm1Ysh/Gpx1tm1Ysh Genetic Background: B6.129-Gpx1tm1Ysh
Allelic Composition: Map1btm1Rak/Map1b+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
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MP:0000857 | abnormal cerebellar foliation | "malformation of small offshoots of the cerebellar lobules" [Principles of Neural Science:ISBN 0-8385-8034-3, J:52951] |
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Allelic Composition: Gpx1tm1Ysh/Gpx1tm1Ysh Genetic Background: B6.129-Gpx1tm1Ysh
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MP:0000877 | abnormal Purkinje cell | "any structural anomaly of the neurons located at the interface of the molecular and internal granule layers of the cerebellar cortex; these inhibitory neurons provide the output of the cerebellar cortex through axons that project into the white matter, and extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells" [J:46140, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3] |
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Allelic Composition: Map1btm1Rak/Map1b+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
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MP:0000920 | abnormal myelination | "atypical or altered myelination in axon sheaths" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Liftm1Cgre/Liftm1Cgre Genetic Background: involves: MF1
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MP:0001262 | decreased body weight | "lower than normal average weight " [J:61295] |
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Allelic Composition: Liftm1Cgre/Liftm1Cgre Genetic Background: involves: MF1
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MP:0001265 | reduced body size | "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170] |
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Allelic Composition: Wnt9btm1.1Amc/Wnt9btm1.1Amc Genetic Background: involves: 129/Sv * 129X1/SvJ * C57BL/6J
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MP:0001286 | abnormal eye development | "malformation or arrest of differentiation of the visual organ" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:49840] |
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Allelic Composition: Map1btm1Rak/Map1b+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
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MP:0001290 | delayed eyelid opening | "late average time for the first postnatal eye opening" [J:17792] |
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Allelic Composition: Liftm1Cgre/Liftm1Cgre Genetic Background: involves: MF1
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MP:0001393 | ataxia | "inability to coordinate voluntary muscular movements" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:67231] |
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Allelic Composition: Map1btm1Rak/Map1b+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
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MP:0001406 | abnormal gait | "unusual or distinctive way of walking" [J:65038] |
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Allelic Composition: Map1btm1Rak/Map1b+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
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MP:0001417 | decreased exploration in new environment | "less amount of time spent investigating a new location" [J:79870] |
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Allelic Composition: Liftm1Cgre/Liftm1Cgre Genetic Background: involves: MF1
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MP:0001429 | dehydration | "excessive water loss from the body or from an organ or bodily part" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:50053] |
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Allelic Composition: Liftm1Cgre/Liftm1Cgre Genetic Background: involves: MF1
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MP:0001491 | unresponsive to tactile stimuli | "absence of reflex action normally induced by touch or pain" [J:43515, J:47439] |
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Allelic Composition: Gpx1tm1Ysh/Gpx1tm1Ysh Genetic Background: B6.129-Gpx1tm1Ysh
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MP:0001921 | reduced fertility | "diminished ability to produce live offspring" [J:65030] |
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Allelic Composition: Liftm1Cgre/Liftm1Cgre Genetic Background: involves: MF1
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MP:0002083 | premature death | "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Map1btm1Rak/Map1b+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
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MP:0002090 | abnormal vision | "inability or decreased ability to see " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Map1btm1Rak/Map1b+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
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MP:0002092 | abnormal eye morphology | "abnormal development of the eye tissues resulting in morphological abnormality or abnormal structure of the visual system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Liftm1Cgre/Liftm1Cgre Genetic Background: involves: MF1
Allelic Composition: Map1btm1Rak/Map1b+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
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MP:0002196 | acallosal | "absence of the commissural plate interconnecting the cortical hemispheres of the brain" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Liftm1Cgre/Liftm1Cgre Genetic Background: involves: MF1
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MP:0002199 | abnormal brain commissure morphology | "absent or defective structure in a bundle of nerve fibers connecting the two brain hemispheres" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Nfe2l1tm1Jefc/Nfe2l1tm1Ywk,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ Genetic Background: involves: 129X1/SvJ * C57BL/6J
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MP:0002882 | abnormal neuron | "anomaly in the functional cells of the nervous system that receive, conduct, and transmit impulses " [MeSH:National Library of Medicine - Medical Subject Headings, 2003] |
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Allelic Composition: Map1btm1Noh/Map1btm1Noh,Map2tm1Noh/Map2tm1Noh Genetic Background: involves: C57BL/6
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MP:0003651 | abnormal axon outgrowth | "defect/abnormality in the ability of an axon to extend from a neuron cell body" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator, J:96121] |
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Allelic Composition: Map1btm1Prop/Map1btm1Prop Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0003684 | abnormal inferior olivary complex | "any structural abnormality in the capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids; neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex and have been implicated in various functions, such as learning and timing of movements" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3] |
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Allelic Composition: Map1btm1Noh/Map1btm1Noh,Map2tm1Noh/Map2tm1Noh Genetic Background: involves: C57BL/6
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MP:0003732 | abnormal outer plexiform layer morphology | "malformation/anomalous structure of the retinal layer that is the site of synapses between the rods and cones (axons) and the horizontal and bipolar cells (dendrites)" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: Map1btm1Rak/Map1b+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
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MP:0003861 | abnormal nervous system development | "impaired or altered growth of the components of the nervous system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Map1btm1Noh/Map1btm1Noh,Map2tm1Noh/Map2tm1Noh Genetic Background: involves: C57BL/6
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MP:0004167 | abnormal cingulate gyrus morphology | "any malformation or absence of the ridge in the cerebral cortex located dorsal to the corpus callosum that controls autonomic functions regulating heart rate and blood pressure as well as cognitive and attentional processing" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Map1btm1Prop/Map1btm1Prop Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0004263 | abnormal limb posture | "atypical position of the limbs compared to the normal carriage of the body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Gpx1tm1Ysh/Gpx1tm1Ysh Genetic Background: B6.129-Gpx1tm1Ysh
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MP:0005202 | lethargy | "mild impairment of consciousness resulting in reduced alertness and awareness; ultimately due to generalized brain dysfunction" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Map1btm1Rak/Map1b+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
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MP:0005403 | abnormal nerve conduction | "anomaly in the act of transmitting electricity along a single nerve" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Map1btm1Prop/Map1btm1Prop Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0005404 | abnormal axon morphology | "anomaly in the structure of the single process of a nerve cell that normally conducts impulses away from the cell body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Map1btm1Prop/Map1btm1Prop Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0008223 | absent hippocampal commissure | "absence of the triangular subcallosal plate of commissural fibers resulting from the converging of the right and left fornix bundles which exchange numerous fibers and which curve back in the contralateral fornix to end in the hippocampus of the opposite side" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Map1btm1Prop/Map1btm1Prop Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0008226 | decreased anterior commissure size | "reduced size of a round bundle of nerve fibers that crosses the midline of the brain near the anterior limit of the third ventricle" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Map1btm1Noh/Map1btm1Noh,Map2tm1Noh/Map2tm1Noh Genetic Background: involves: C57BL/6
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MP:0008443 | absent subplate | "absence of the transient outer neural tube region that contains the first generated post-mitotic neurons that receive synaptic input from thalamic axons and in turn project axons to the developing cortical plate" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", PMID:8210173] |
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Allelic Composition: Gpx1tm1Ysh/Gpx1tm1Ysh Genetic Background: B6.129-Gpx1tm1Ysh
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MP:0008512 | disorganized retinal inner nuclear layer | "derangement of the normal pattern of the retinal layer which contains the cell bodies of bipolar, horizontal, and amacrine cells" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"] |
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Allelic Composition: Map1btm1Rak/Map1b+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
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MP:0008516 | disorganized retinal outer nuclear layer | "derangement of the normal pattern of the retinal layer that contains the nuclei and cell bodies of rods and cones" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"] |
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Allelic Composition: Map1btm1Rak/Map1b+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
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MP:0008535 | enlarged lateral ventricles | "increased size of the cavity in each of the cerebral hemispheres derived from the cavity of the embryonic neural tube; they are separated from each other by the septum pellucidum, and each communicates with the third ventricle by the foramen of Monro, through which also the choroid plexuses of the lateral ventricles become continuous with that of the third ventricle" [MESH:A08.186.211.276.650, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Gpx1tm1Ysh/Gpx1tm1Ysh Genetic Background: B6.129-Gpx1tm1Ysh
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MP:0008536 | enlarged third ventricle | "increased size of the narrow cleft inferior to the corpus callosum, within the diencephalon, between the paired thalami; its floor is formed by the hypothalamus, its anterior wall by the lamina terminalis, and its roof by ependyma; it communicates with the fourth ventricle by the cerebral aqueduct, and with the lateral ventricles by the interventricular foramina" [MESH:A08.186.211.276.840, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Gpx1tm1Ysh/Gpx1tm1Ysh Genetic Background: B6.129-Gpx1tm1Ysh
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MP:0008572 | abnormal Purkinje cell dendrite morphology | "any strucutral anomaly of the Purkinje cell body projections with hundreds of parallel spiny branches reaching up into the molecular layer" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Map1btm1Rak/Map1b+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
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MP:0011086 | partial postnatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
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Allelic Composition: Map1btm1Prop/Map1btm1Prop Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0011087 | complete neonatal lethality | "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith] |
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Allelic Composition: Gpx1tm1Ysh/Gpx1tm1Ysh Genetic Background: B6.129-Gpx1tm1Ysh
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MP:0011089 | complete perinatal lethality | "death of all organisms of a given genotype in a population within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith] |
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Allelic Composition: Map1btm1Noh/Map1btm1Noh,Map2tm1Noh/Map2tm1Noh Genetic Background: involves: C57BL/6
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MP:0011097 | complete embryonic lethality before turning of embryo | "death of all organisms of a given genotype in a population between somite formation and the initiation of embryo turning (Mus: E8 to less than E9)" [MGI:csmith] |
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Allelic Composition: Wnt9btm1.1Amc/Wnt9btm1.1Amc Genetic Background: involves: 129/Sv * 129X1/SvJ * C57BL/6J
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