ENSMUSG00000019278


Mus musculus

Features
Gene ID: ENSMUSG00000019278
  
Biological name :Dpep1
  
Synonyms : Dipeptidase 1 / Dpep1 / P31428
  
Possible biological names infered from orthology : P16444
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: E1
Gene start: 123186242
Gene end: 123201812
  
Corresponding Affymetrix probe sets: 10576235 (MoGene1.0st)   1419674_a_at (Mouse Genome 430 2.0 Array)   1435943_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000019422
Ensembl peptide - ENSMUSP00000148823
Ensembl peptide - ENSMUSP00000148609
NCBI entrez gene - 13479     See in Manteia.
MGI - MGI:94917
RefSeq - NM_007876
RefSeq - XM_017312558
RefSeq Peptide - NP_031902
swissprot - A0A1D5RML1
swissprot - P31428
swissprot - A0A1D5RM32
Ensembl - ENSMUSG00000019278
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dpep1ENSDARG00000068181Danio rerio
 DPEP1ENSGALG00000006175Gallus gallus
 DPEP1ENSG00000015413Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Dpep2 / Q8C255 / Dipeptidase 2 / Q9H4A9*ENSMUSG0000005368745
Dpep2 / Q8C255 / Dipeptidase 2 / Q9H4A9*ENSMUSG0000011506744
Dpep3 / Q9DA79 / Dipeptidase 3 / Q9H4B8*ENSMUSG0000003189844


Protein motifs (from Interpro)
Interpro ID Name
 IPR000180  Membrane dipeptidase, active site
 IPR008257  Peptidase M19
 IPR028536  Dipeptidase 1
 IPR032466  Metal-dependent hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0016999 antibiotic metabolic process IEA
 biological_processGO:0030336 negative regulation of cell migration IEA
 biological_processGO:0035690 cellular response to drug IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:0050667 homocysteine metabolic process IEA
 biological_processGO:0071277 cellular response to calcium ion ISS
 biological_processGO:0071732 cellular response to nitric oxide ISS
 cellular_componentGO:0005615 extracellular space ISS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0031225 anchored component of membrane IEA
 cellular_componentGO:0031528 microvillus membrane IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0045177 apical part of cell IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008235 metalloexopeptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0008239 dipeptidyl-peptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016805 dipeptidase activity IEA
 molecular_functionGO:0034235 GPI anchor binding ISS
 molecular_functionGO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070573 metallodipeptidase activity IEA
 molecular_functionGO:0072341 modified amino acid binding IEA


Pathways (from Reactome)
Pathway description
Synthesis of Leukotrienes (LT) and Eoxins (EX)
Aflatoxin activation and detoxification


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Pax3Sp/Pax3+
Genetic Background: involves: C3HeB * C57BL * C57BL/6J * SWV

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000019278 Dpep1 / P31428 / Dipeptidase 1 / P16444*  / complex






 

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