ENSMUSG00000019732


Mus musculus

Features
Gene ID: ENSMUSG00000019732
  
Biological name :Calr3
  
Synonyms : Calr3 / Calreticulin-3 / Q9D9Q6
  
Possible biological names infered from orthology : Q96L12
  
Species: Mus musculus
  
Chr. number: 8
Strand: -1
Band: B3.3
Gene start: 72424176
Gene end: 72443870
  
Corresponding Affymetrix probe sets: 10579691 (MoGene1.0st)   1431255_at (Mouse Genome 430 2.0 Array)   1453232_at (Mouse Genome 430 2.0 Array)   1453233_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000019876
Ensembl peptide - ENSMUSP00000105601
NCBI entrez gene - 73316     See in Manteia.
MGI - MGI:1920566
RefSeq - XM_006509761
RefSeq - NM_028500
RefSeq - NM_029782
RefSeq Peptide - NP_084058
RefSeq Peptide - NP_082776
swissprot - Q8BL82
swissprot - Q9D9Q6
Ensembl - ENSMUSG00000019732
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CALR3ENSGALG00000003914Gallus gallus
 CALR3ENSG00000269058Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Calr / P14211 / Calreticulin / P27797*ENSMUSG0000000381449
Calr4 / calreticulin 4ENSMUSG0000002855842
Canx / P35564 / Calnexin / P27824*ENSMUSG0000002036831
Clgn / P52194 / Mus musculus calmegin (Clgn), transcript variant 2, mRNA. / O14967* / calmegin*ENSMUSG0000000219029


Protein motifs (from Interpro)
Interpro ID Name
 IPR001580  Calreticulin/calnexin
 IPR009033  Calreticulin/calnexin, P domain superfamily
 IPR009169  Calreticulin
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR018124  Calreticulin/calnexin, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006457 protein folding IEA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0030154 cell differentiation IEA
 cellular_componentGO:0005635 nuclear envelope IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005788 endoplasmic reticulum lumen ISO
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0044183 protein binding involved in protein folding IMP
 molecular_functionGO:0051082 unfolded protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000242 impaired fertilization "defect or reduced ability in the process beginning with penetration of the secondary oocyte by the spermatozoon and completed by fusion of the male and female pronucei" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Xrcc1tm1Pmc/Xrcc1tm1Pmc,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S1/Sv * FVB/N

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
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Allelic Composition: Xrcc1tm1Pmc/Xrcc1tm1Pmc,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S1/Sv * FVB/N

 MP:0004543 abnormal sperm physiology "anomaly in the normal function of spermatozoa" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
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Allelic Composition: Xrcc1tm1Pmc/Xrcc1tm1Pmc,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S1/Sv * FVB/N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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