ENSMUSG00000002190


Mus musculus

Features
Gene ID: ENSMUSG00000002190
  
Biological name :Clgn
  
Synonyms : Clgn / Mus musculus calmegin (Clgn), transcript variant 2, mRNA. / P52194
  
Possible biological names infered from orthology : calmegin / O14967
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: C2
Gene start: 83389867
Gene end: 83428552
  
Corresponding Affymetrix probe sets: 10573172 (MoGene1.0st)   1418617_x_at (Mouse Genome 430 2.0 Array)   1430240_a_at (Mouse Genome 430 2.0 Array)   1457829_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000002259
Ensembl peptide - ENSMUSP00000105457
NCBI entrez gene - 12745     See in Manteia.
MGI - MGI:107472
RefSeq - XM_017312554
RefSeq - NM_001329627
RefSeq - NM_009904
RefSeq - XM_011248296
RefSeq - XM_011248297
RefSeq - XM_011248298
RefSeq - XM_006530635
RefSeq - XM_006530636
RefSeq Peptide - NP_034034
RefSeq Peptide - NP_001316556
swissprot - P52194
Ensembl - ENSMUSG00000002190
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 clgnENSDARG00000009315Danio rerio
 CLGNENSGALG00000009826Gallus gallus
 CLGNENSG00000153132Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Canx / P35564 / Calnexin / P27824*ENSMUSG0000002036855
Calr / P14211 / Calreticulin / P27797*ENSMUSG0000000381427
Calr4 / calreticulin 4ENSMUSG0000002855824
Calr3 / Q9D9Q6 / Calreticulin-3 / Q96L12*ENSMUSG0000001973218


Protein motifs (from Interpro)
Interpro ID Name
 IPR001580  Calreticulin/calnexin
 IPR009033  Calreticulin/calnexin, P domain superfamily
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR018124  Calreticulin/calnexin, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006457 protein folding IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0007338 single fertilization IGI
 biological_processGO:0007339 binding of sperm to zona pellucida IMP
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0051321 meiotic cell cycle IEA
 cellular_componentGO:0005635 nuclear envelope IDA
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005509 calcium ion binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0044183 protein binding involved in protein folding IMP
 molecular_functionGO:0051082 unfolded protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000242 impaired fertilization "defect or reduced ability in the process beginning with penetration of the secondary oocyte by the spermatozoon and completed by fusion of the male and female pronucei" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Foxg1tm1(tTA)Lai/Foxg1tm1M,Tg(tetO-Foxg1)1Lai/0
Genetic Background: involves: 129S1/Sv * C57BL/6

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Foxg1tm1(tTA)Lai/Foxg1tm1M,Tg(tetO-Foxg1)1Lai/0
Genetic Background: involves: 129S1/Sv * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr